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The map label for this gene is dsbE [H]

Identifier: 225851637

GI number: 225851637

Start: 102418

End: 103029

Strand: Direct

Name: dsbE [H]

Synonym: BMEA_A0103

Alternate gene names: 225851637

Gene position: 102418-103029 (Clockwise)

Preceding gene: 225851636

Following gene: 225851639

Centisome position: 4.82

GC content: 59.31

Gene sequence:

>612_bases
ATGACCGAAACAACCGAAAAACCCGCCGCGCAGAAAAAGCGCGCAAGCTGGGTGGCCCTCCTGCCATTGCTGATTTTCGT
AGGGCTGGCCGCGGTTTTCGCGGTACAGCTTCTGTCGGGCAAGGATAACAGCATCATTCCGTCGGTATTGATCGGCAAGC
AGGCGCCGTTGACCAATCTGCCGCCCGTGGAAGGGCTGATGCGCGATGGCGCGCCAGTTTCGGGCTTCAACAGCGAAGAC
CTGAAAACGGGGCCGGGGGGCAAGCTTACCCTGGTCAATGTCTGGGGTTCGTGGTGCGTGCCCTGCCGTCAGGAGCACCC
GCTCCTGATGGAAATCGCCAAGGACGAGCGCATCCGCGTGGTTGGCATCAATTACAAGGACCAACCGGAAAATGCGCGTC
GTTTTCTGGGTGATCTCGGCAATCCGTTTGCCGCCGTTGGCGCCGACCGCGCCGGACGCTCCGCCATCGAATGGGGCGTC
TATGGCGTACCGGAAACCTTCCTCGTCGATCAGACTGGCAAGATCGTCTACAAGCATGTCGGCCCATTTACGCCGGAATC
GGTGAAAAACGATCTGCTGCCTGCTGTGGAAAAGGCTCTTCAACAACGATAG

Upstream 100 bases:

>100_bases
GCTGGATATTGATTGACCAGCGCATCCAGAAAAACGAGCTGAAGCGGCTTGAGGCGCAGGGCGTGCGCCGCCGTTCTGCA
AAAGCCCCCGGTAAGGCACA

Downstream 100 bases:

>100_bases
AGCATTTTCGAGCCAAAAGTGTGAAACGCCTACGCGGGGAAATCAGTCCACTGGACTGATTTCTGATCCCGCTTCGATAC
GTAGGATAATGCGATAAAAC

Product: periplasmic protein thiol:disulfide oxidoreductase

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CycY [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTETTEKPAAQKKRASWVALLPLLIFVGLAAVFAVQLLSGKDNSIIPSVLIGKQAPLTNLPPVEGLMRDGAPVSGFNSED
LKTGPGGKLTLVNVWGSWCVPCRQEHPLLMEIAKDERIRVVGINYKDQPENARRFLGDLGNPFAAVGADRAGRSAIEWGV
YGVPETFLVDQTGKIVYKHVGPFTPESVKNDLLPAVEKALQQR

Sequences:

>Translated_203_residues
MTETTEKPAAQKKRASWVALLPLLIFVGLAAVFAVQLLSGKDNSIIPSVLIGKQAPLTNLPPVEGLMRDGAPVSGFNSED
LKTGPGGKLTLVNVWGSWCVPCRQEHPLLMEIAKDERIRVVGINYKDQPENARRFLGDLGNPFAAVGADRAGRSAIEWGV
YGVPETFLVDQTGKIVYKHVGPFTPESVKNDLLPAVEKALQQR
>Mature_202_residues
TETTEKPAAQKKRASWVALLPLLIFVGLAAVFAVQLLSGKDNSIIPSVLIGKQAPLTNLPPVEGLMRDGAPVSGFNSEDL
KTGPGGKLTLVNVWGSWCVPCRQEHPLLMEIAKDERIRVVGINYKDQPENARRFLGDLGNPFAAVGADRAGRSAIEWGVY
GVPETFLVDQTGKIVYKHVGPFTPESVKNDLLPAVEKALQQR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=184, Percent_Identity=40.7608695652174, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 22010; Mature: 21879

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTEKPAAQKKRASWVALLPLLIFVGLAAVFAVQLLSGKDNSIIPSVLIGKQAPLTNL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCC
PPVEGLMRDGAPVSGFNSEDLKTGPGGKLTLVNVWGSWCVPCRQEHPLLMEIAKDERIRV
CCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCEEEE
VGINYKDQPENARRFLGDLGNPFAAVGADRAGRSAIEWGVYGVPETFLVDQTGKIVYKHV
EECCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCCEEEECC
GPFTPESVKNDLLPAVEKALQQR
CCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TETTEKPAAQKKRASWVALLPLLIFVGLAAVFAVQLLSGKDNSIIPSVLIGKQAPLTNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCC
PPVEGLMRDGAPVSGFNSEDLKTGPGGKLTLVNVWGSWCVPCRQEHPLLMEIAKDERIRV
CCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCEEEE
VGINYKDQPENARRFLGDLGNPFAAVGADRAGRSAIEWGVYGVPETFLVDQTGKIVYKHV
EECCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCCEEEECC
GPFTPESVKNDLLPAVEKALQQR
CCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]