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The map label for this gene is 225851621

Identifier: 225851621

GI number: 225851621

Start: 87507

End: 87800

Strand: Reverse

Name: 225851621

Synonym: BMEA_A0085

Alternate gene names: NA

Gene position: 87800-87507 (Counterclockwise)

Preceding gene: 225851622

Following gene: 225851620

Centisome position: 4.13

GC content: 54.76

Gene sequence:

>294_bases
ATGGCACGCAACCGATTGACGGAAAGCGAAATGAACGAGGCGCTCAGGGCGCTGGACGGCTGGCAGAAAGTTGATGGGCG
CGAGGCAATCACTCGCAGCTTCAAATTCAAGGATTTCAGCACCGCCTTCGGTTTCATGGCGCAGGCAGCACTTTACGCAG
AAAAGCTCGACCATCACCCCGAATGGTTCAATGCCTATAACCGTGTGGACGTAACACTTGCGACCCACAGCGAAAACGGG
GTTACAGAACTGGATATCAAGATGGCGCGCAAGATGAACGCGATCGCCGGTTGA

Upstream 100 bases:

>100_bases
TACCAAACCACAAGTTAATCCGTCACTACAGCCTGGTATAATCACGGAACTCTCACGGCTTTGGTCGGTTGATATAAACC
CGCAACATAGGCGAAAGACG

Downstream 100 bases:

>100_bases
GGCAAAAACTTGCGAAGCGGGGCGATAATCCCCATTTTCTGGTCTTGTGCGCGGTTTGAGAGCCTGCGCGACAGGAGTTG
AACCAGGATGGATGACGTCA

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MARNRLTESEMNEALRALDGWQKVDGREAITRSFKFKDFSTAFGFMAQAALYAEKLDHHPEWFNAYNRVDVTLATHSENG
VTELDIKMARKMNAIAG

Sequences:

>Translated_97_residues
MARNRLTESEMNEALRALDGWQKVDGREAITRSFKFKDFSTAFGFMAQAALYAEKLDHHPEWFNAYNRVDVTLATHSENG
VTELDIKMARKMNAIAG
>Mature_96_residues
ARNRLTESEMNEALRALDGWQKVDGREAITRSFKFKDFSTAFGFMAQAALYAEKLDHHPEWFNAYNRVDVTLATHSENGV
TELDIKMARKMNAIAG

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI4557831, Length=95, Percent_Identity=50.5263157894737, Blast_Score=103, Evalue=4e-23,
Organism=Homo sapiens, GI134133240, Length=89, Percent_Identity=47.1910112359551, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115533705, Length=93, Percent_Identity=53.763440860215, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45549100, Length=94, Percent_Identity=52.1276595744681, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_BRUA1 (B2S7X9)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001934107.1
- ProteinModelPortal:   B2S7X9
- SMR:   B2S7X9
- GeneID:   6328021
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I00730
- HOGENOM:   HBG705804
- OMA:   SEERKTR
- ProtClustDB:   PRK00823
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11055; Mature: 10923

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNRLTESEMNEALRALDGWQKVDGREAITRSFKFKDFSTAFGFMAQAALYAEKLDHHP
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
EWFNAYNRVDVTLATHSENGVTELDIKMARKMNAIAG
HHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARNRLTESEMNEALRALDGWQKVDGREAITRSFKFKDFSTAFGFMAQAALYAEKLDHHP
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
EWFNAYNRVDVTLATHSENGVTELDIKMARKMNAIAG
HHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA