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The map label for this gene is aroA [H]

Identifier: 225851569

GI number: 225851569

Start: 29375

End: 30727

Strand: Direct

Name: aroA [H]

Synonym: BMEA_A0026

Alternate gene names: 225851569

Gene position: 29375-30727 (Clockwise)

Preceding gene: 225851561

Following gene: 225851570

Centisome position: 1.38

GC content: 61.12

Gene sequence:

>1353_bases
ATGTCCCATTCCGCATGCCCGAAACCAGCAACCGCCCGCCATTCGCAGGCACTTACGGGCGAAATCCGCATTCCGGGCGA
TAAATCCATTTCCCACCGCTCCTTCATGTTTGGTGGCCTTGCATCGGGTAAAACCCGCATCACCGGCCTGCTTGAGGGCG
AAGACGTTATCAACACCGGGCGTGCCATGCAGGCCATGGGTGCCAGGATTCGCAAGGAAGGCGATGTCTGGATCATCAAT
GGTGTCGGCAATGGCTGCCTGTTGCAGCCCGAAGCGCCGCTTGATTTCGGCAATGCCGGAACCGGCGCGCGCCTGACCAT
GGGCCTCGTCGGCACGTATGATATGAAGACGTCTTTTATCGGCGATGCCTCGCTTTCCAAGCGCCCGATGGGCCGCGTGC
TGAACCCGCTGCGTGAAATGGGTGTTCAGGTTGAGGCCGCCGAAGGCGACCGGATGCCGCTGACGCTGATTGGCCCAAGG
ACGGCCAACCCGATCGCCTATCGCGTGCCGATGGCTTCCGCACAGGTGAAATCCGCCGTTCTGCTCGCTGGTCTTAACAC
CCCGGGCGTCACCACCGTGATCGAGCCGGTCATGACGCGCGATCATACGGAAAAGATGCTGCAAGGCTTTGGCGCAGACC
TGACGGTTGAAACCGATAAGGATGGTGTGCGCCATATCCGTATTGTCGGCCAGGGCAAGCTTACCGGCCAGACCATCGAC
GTGCCGGGTGATCCCTCGTCAACGGCTTTTCCGCTGGTGGCCGCCCTTCTGGTCGAAGGTTCGGACGTCACCATCCGCAA
TGTGCTGATGAACCCGACCCGCACCGGCCTGATCCTGACGTTGCAGGAAATGGGGGCGGATATCGAGATCATCGATCCAC
GCCTTGCCGGCGGCGAGGATGTCGCCGATCTGCGCGTCAAGGCCTCGAAGCTGAAAGGCGTTGTCGTTCCGCCGGAACGT
GCGCCTTCGATGATCGATGAATATCCGGTTCTGGCCATTGCCGCGTCTTTTGCGGAAGGCGAAACCGTGATGGACGGTCT
CGATGAACTGCGCGTCAAGGAATCGGATCGTCTGGCGGCCGTTGCGCGCGGCCTTGAAGCCAATGGTGTCGATTGTACCG
AAGGCGAGATGTCGCTGACGGTTCGTGGCCGCCCCGGCGGCAAGGGGCTGGGCGGTGGCACGGTTGCAACCCACCTCGAC
CACCGCATCGCGATGAGTTTCCTCGTCATGGGCCTTGCATCGGAAAAGCCGGTTACGGTGGATGACAGCACCATGATCGC
CACCTCTTTCCCGGAATTCATGGGCATGATGGCGGGGCTGGGGGCGAAGATTGCCGAAAGCGGTGCAGAATGA

Upstream 100 bases:

>100_bases
TTATTCACGGATGACCACACAATATTACTATGCTAGGAAGACTGCGCTTATCTCTCAATCCCGGCGCGTGTCCGCGCCAA
AATGTGACTGTGAAAAATCC

Downstream 100 bases:

>100_bases
AATCGTTCGTCGTCGCCCCGTTCATTGTCGCCATTGACGGACCGGCCGCCTCGGGCAAGGGAACCCTTGCCCGGCGGATC
GCGACACATTACGGGATGCC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSHSACPKPATARHSQALTGEIRIPGDKSISHRSFMFGGLASGKTRITGLLEGEDVINTGRAMQAMGARIRKEGDVWIIN
GVGNGCLLQPEAPLDFGNAGTGARLTMGLVGTYDMKTSFIGDASLSKRPMGRVLNPLREMGVQVEAAEGDRMPLTLIGPR
TANPIAYRVPMASAQVKSAVLLAGLNTPGVTTVIEPVMTRDHTEKMLQGFGADLTVETDKDGVRHIRIVGQGKLTGQTID
VPGDPSSTAFPLVAALLVEGSDVTIRNVLMNPTRTGLILTLQEMGADIEIIDPRLAGGEDVADLRVKASKLKGVVVPPER
APSMIDEYPVLAIAASFAEGETVMDGLDELRVKESDRLAAVARGLEANGVDCTEGEMSLTVRGRPGGKGLGGGTVATHLD
HRIAMSFLVMGLASEKPVTVDDSTMIATSFPEFMGMMAGLGAKIAESGAE

Sequences:

>Translated_450_residues
MSHSACPKPATARHSQALTGEIRIPGDKSISHRSFMFGGLASGKTRITGLLEGEDVINTGRAMQAMGARIRKEGDVWIIN
GVGNGCLLQPEAPLDFGNAGTGARLTMGLVGTYDMKTSFIGDASLSKRPMGRVLNPLREMGVQVEAAEGDRMPLTLIGPR
TANPIAYRVPMASAQVKSAVLLAGLNTPGVTTVIEPVMTRDHTEKMLQGFGADLTVETDKDGVRHIRIVGQGKLTGQTID
VPGDPSSTAFPLVAALLVEGSDVTIRNVLMNPTRTGLILTLQEMGADIEIIDPRLAGGEDVADLRVKASKLKGVVVPPER
APSMIDEYPVLAIAASFAEGETVMDGLDELRVKESDRLAAVARGLEANGVDCTEGEMSLTVRGRPGGKGLGGGTVATHLD
HRIAMSFLVMGLASEKPVTVDDSTMIATSFPEFMGMMAGLGAKIAESGAE
>Mature_449_residues
SHSACPKPATARHSQALTGEIRIPGDKSISHRSFMFGGLASGKTRITGLLEGEDVINTGRAMQAMGARIRKEGDVWIING
VGNGCLLQPEAPLDFGNAGTGARLTMGLVGTYDMKTSFIGDASLSKRPMGRVLNPLREMGVQVEAAEGDRMPLTLIGPRT
ANPIAYRVPMASAQVKSAVLLAGLNTPGVTTVIEPVMTRDHTEKMLQGFGADLTVETDKDGVRHIRIVGQGKLTGQTIDV
PGDPSSTAFPLVAALLVEGSDVTIRNVLMNPTRTGLILTLQEMGADIEIIDPRLAGGEDVADLRVKASKLKGVVVPPERA
PSMIDEYPVLAIAASFAEGETVMDGLDELRVKESDRLAAVARGLEANGVDCTEGEMSLTVRGRPGGKGLGGGTVATHLDH
RIAMSFLVMGLASEKPVTVDDSTMIATSFPEFMGMMAGLGAKIAESGAE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=436, Percent_Identity=30.5045871559633, Blast_Score=121, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6320332, Length=476, Percent_Identity=26.2605042016807, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 47222; Mature: 47091

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSACPKPATARHSQALTGEIRIPGDKSISHRSFMFGGLASGKTRITGLLEGEDVINTG
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHHHCC
RAMQAMGARIRKEGDVWIINGVGNGCLLQPEAPLDFGNAGTGARLTMGLVGTYDMKTSFI
HHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCEEEEEEEEEECCCHHCC
GDASLSKRPMGRVLNPLREMGVQVEAAEGDRMPLTLIGPRTANPIAYRVPMASAQVKSAV
CCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCEEEEECCCHHHHCCEE
LLAGLNTPGVTTVIEPVMTRDHTEKMLQGFGADLTVETDKDGVRHIRIVGQGKLTGQTID
EEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCEEE
VPGDPSSTAFPLVAALLVEGSDVTIRNVLMNPTRTGLILTLQEMGADIEIIDPRLAGGED
CCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEHHHHCCCEEEECCCCCCCCC
VADLRVKASKLKGVVVPPERAPSMIDEYPVLAIAASFAEGETVMDGLDELRVKESDRLAA
HHHHEEEHHHCCEEEECCCCCCHHHHCCCEEEEEEHHCCCHHHHHHHHHHHCCCCCHHHH
VARGLEANGVDCTEGEMSLTVRGRPGGKGLGGGTVATHLDHRIAMSFLVMGLASEKPVTV
HHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
DDSTMIATSFPEFMGMMAGLGAKIAESGAE
CCCEEEEECCHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure 
SHSACPKPATARHSQALTGEIRIPGDKSISHRSFMFGGLASGKTRITGLLEGEDVINTG
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHHHCC
RAMQAMGARIRKEGDVWIINGVGNGCLLQPEAPLDFGNAGTGARLTMGLVGTYDMKTSFI
HHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCEEEEEEEEEECCCHHCC
GDASLSKRPMGRVLNPLREMGVQVEAAEGDRMPLTLIGPRTANPIAYRVPMASAQVKSAV
CCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCEEEEECCCHHHHCCEE
LLAGLNTPGVTTVIEPVMTRDHTEKMLQGFGADLTVETDKDGVRHIRIVGQGKLTGQTID
EEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCEEE
VPGDPSSTAFPLVAALLVEGSDVTIRNVLMNPTRTGLILTLQEMGADIEIIDPRLAGGED
CCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEHHHHCCCEEEECCCCCCCCC
VADLRVKASKLKGVVVPPERAPSMIDEYPVLAIAASFAEGETVMDGLDELRVKESDRLAA
HHHHEEEHHHCCEEEECCCCCCHHHHCCCEEEEEEHHCCCHHHHHHHHHHHCCCCCHHHH
VARGLEANGVDCTEGEMSLTVRGRPGGKGLGGGTVATHLDHRIAMSFLVMGLASEKPVTV
HHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
DDSTMIATSFPEFMGMMAGLGAKIAESGAE
CCCEEEEECCHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA