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The map label for this gene is nuoC [H]

Identifier: 225630973

GI number: 225630973

Start: 1382788

End: 1383360

Strand: Reverse

Name: nuoC [H]

Synonym: WRi_012950

Alternate gene names: 225630973

Gene position: 1383360-1382788 (Counterclockwise)

Preceding gene: 225630974

Following gene: 225630972

Centisome position: 95.68

GC content: 34.73

Gene sequence:

>573_bases
ATGGATAAAACTGCAAAGTATATACAAAAAAAGACCAAATGCGAGTGCATTCAAAAAGATGATGGCATTATTGTAATATA
TTCAACTTTAGATGAAATTGAAAAGCACCTATTCTTTCTACGTGATGATGAAAAGTGTAGGTTTGAACTATTAGTTGATA
TTTTTGGGGTTGACTATCCAAATAGAGAGAAGCGTTTCGAGCTAATATACAATCTGCTCAGCATTGTGCATAATATTAGA
GTACACATAAAGCTTCAGTTATGTGAAAGCGACATGCCTCCAAGTGTAGCGAAGATATTTAGTACGGCTTTGTGGTTTGA
GCGTGAAGTGTTTGATATGTATGGAATAGAGTTTTCTGATCACCCTGATTTGCGTAGGATTCTAACAGACTATGGATTCA
AAGGTCATCCAATGTTAAAAGATTTCCCTCTCACTGGTTATGAGGAAGTAAGATATGATATAGAGACAAAAAAGGTTGTG
TATAATCCTATAGATTTACCGCAAGATTTTCGTATGTTTGATAGCTTATCGCCTTGGGAAGGTAAAACCATAAAAGTAAA
TACAAAGGAGTAG

Upstream 100 bases:

>100_bases
ATTGTGCCAGTTGACGTGTATGTCCCTGGATGCCCACCAACCGCTGAGGCGTTGCTATATGGAATGCTATGCCTACAAAA
CAAAATAAAACGGACTCGGA

Downstream 100 bases:

>100_bases
AAAATGACAGTACAAAGAAAAAAAATATCTTTAATCGGTGCAGGAAATATCGGTGGAACTCTCACCCATATGATTGCACT
AAGGGAACTCGGTGATGTTG

Product: NADH dehydrogenase I, C subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MDKTAKYIQKKTKCECIQKDDGIIVIYSTLDEIEKHLFFLRDDEKCRFELLVDIFGVDYPNREKRFELIYNLLSIVHNIR
VHIKLQLCESDMPPSVAKIFSTALWFEREVFDMYGIEFSDHPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIETKKVV
YNPIDLPQDFRMFDSLSPWEGKTIKVNTKE

Sequences:

>Translated_190_residues
MDKTAKYIQKKTKCECIQKDDGIIVIYSTLDEIEKHLFFLRDDEKCRFELLVDIFGVDYPNREKRFELIYNLLSIVHNIR
VHIKLQLCESDMPPSVAKIFSTALWFEREVFDMYGIEFSDHPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIETKKVV
YNPIDLPQDFRMFDSLSPWEGKTIKVNTKE
>Mature_190_residues
MDKTAKYIQKKTKCECIQKDDGIIVIYSTLDEIEKHLFFLRDDEKCRFELLVDIFGVDYPNREKRFELIYNLLSIVHNIR
VHIKLQLCESDMPPSVAKIFSTALWFEREVFDMYGIEFSDHPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIETKKVV
YNPIDLPQDFRMFDSLSPWEGKTIKVNTKE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=181, Percent_Identity=47.5138121546961, Blast_Score=171, Evalue=4e-43,
Organism=Escherichia coli, GI145693162, Length=131, Percent_Identity=34.3511450381679, Blast_Score=87, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=144, Percent_Identity=52.7777777777778, Blast_Score=162, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32563621, Length=144, Percent_Identity=52.7777777777778, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24656494, Length=180, Percent_Identity=46.1111111111111, Blast_Score=166, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22647; Mature: 22647

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTAKYIQKKTKCECIQKDDGIIVIYSTLDEIEKHLFFLRDDEKCRFELLVDIFGVDYP
CCHHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCC
NREKRFELIYNLLSIVHNIRVHIKLQLCESDMPPSVAKIFSTALWFEREVFDMYGIEFSD
CHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
HPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIETKKVVYNPIDLPQDFRMFDSLSPWE
CHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEECCCCCEEEECCCCCCHHHHHHCCCCCCC
GKTIKVNTKE
CCEEEEECCC
>Mature Secondary Structure
MDKTAKYIQKKTKCECIQKDDGIIVIYSTLDEIEKHLFFLRDDEKCRFELLVDIFGVDYP
CCHHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCC
NREKRFELIYNLLSIVHNIRVHIKLQLCESDMPPSVAKIFSTALWFEREVFDMYGIEFSD
CHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
HPDLRRILTDYGFKGHPMLKDFPLTGYEEVRYDIETKKVVYNPIDLPQDFRMFDSLSPWE
CHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEECCCCCEEEECCCCCCHHHHHHCCCCCCC
GKTIKVNTKE
CCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA