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The map label for this gene is sucC [H]

Identifier: 225630876

GI number: 225630876

Start: 1279196

End: 1280347

Strand: Reverse

Name: sucC [H]

Synonym: WRi_011880

Alternate gene names: 225630876

Gene position: 1280347-1279196 (Counterclockwise)

Preceding gene: 225630877

Following gene: 225630875

Centisome position: 88.55

GC content: 36.81

Gene sequence:

>1152_bases
ATGAATATTCACGAATATCAAGCGAAAGAAGTTTTACATAAATTTAATGTCTCAGTGCCAAAAGGTTTTGTTGCTACATC
TGCGGAAGAAGTAAAGACTCAAGTAAGTCAATTAAAATCTGACGTGTTTGTAGTTAAAGCTCAAATTCATGCAGGTGGTA
GGGGTAAAGCCGGTGGCGTAAAGCTAGCAAAGTCAGCTGAAGAAGCTCAACAGTTTGTAAAGGACATGATTGGTATGACT
TTAGTTACTCATCAAACAGGGCCAAGCGGGCAGCAAGTAAGAAAAGTGTACGTTGAAGAAGGCTCAAGCATTAAGAAAGA
GTATTATTTAAGCCTGGTAATCGACCCGAAGCTCAGTAGGCCAATATTCATATTTTCCTCAGAAGGTGGAATGGACATTG
AAGAAGTGGCGAAAAATTCTCCCGCAAAAATTGTGAAATTTGATATTGATTCTGCTACAAGTTTTGATAGCAGCAAGTTA
AGCAGCAGTTTTCATTTGAGTCCAGAACAAATAGAAAAAATAACAAATGTTGCAAAAAATATATATGATGCGTTTATTGC
AACTGATGCGAGCCAAATTGAAATTAATCCACTGGTTGAAACAAGTTCTGGAGATTTTATTGCGCTCGATGCGAAAATTA
ATTTCGATGATAATGCTTTATATCGTCACCCAGAAATTATGGAACTTCGTGATTATGATGAAGAAGTGAAAGAAGAGATA
GAGGCTTCAAAGTATGGGCTCAGTTACATCAAAATGGATGGCAGTATTGGTTGCATGGTAAATGGTGCAGGTCTTGCTAT
GGCAACAATGGATATAATAAAATACTACGGAGCAGAGCCTGCTAACTTTTTGGATGTTGGTGGTGGAGCGAGTAAAGAAA
CTGTAACTGAAGCATTTAAAATCATATTGTCTGATAGCAACGTAAAAGGAATTCTGGTTAACATATTTGGTGGTATAATG
CGTTGCGATATTATCGCAAGTGGAATTGTTGCGGCTGCAAAAGAAATGAGCATTAAAGTTCCTCTAGTGGTTAGATTATC
AGGTACTAATTTTGAAGAAGGAAAAAAAATCTTAGAAGAGTCAGGATTAAATATTATTGCTGCAGATGAACTGGGTGATG
CTGCACAAAAGATAGTAAAAGAGGTAAAATAA

Upstream 100 bases:

>100_bases
AAAGCTGAAGCTAAAAAAAAGAGGTACCAACAAGAGTGCAGAAGGCAGCGTTATGGTTGGTAGTTTGTACTCAAGTTAAT
AGTTTATCATTGGTTATTTT

Downstream 100 bases:

>100_bases
AGCATGTCCGTTTTAGTAAACAAAGATACAAGATTAATATGCCAGGGTTTTACTGGTGCACAAGGCACATTTCATTCAGA
GCAAGCAATTGATTACGGAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MNIHEYQAKEVLHKFNVSVPKGFVATSAEEVKTQVSQLKSDVFVVKAQIHAGGRGKAGGVKLAKSAEEAQQFVKDMIGMT
LVTHQTGPSGQQVRKVYVEEGSSIKKEYYLSLVIDPKLSRPIFIFSSEGGMDIEEVAKNSPAKIVKFDIDSATSFDSSKL
SSSFHLSPEQIEKITNVAKNIYDAFIATDASQIEINPLVETSSGDFIALDAKINFDDNALYRHPEIMELRDYDEEVKEEI
EASKYGLSYIKMDGSIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFKIILSDSNVKGILVNIFGGIM
RCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKILEESGLNIIAADELGDAAQKIVKEVK

Sequences:

>Translated_383_residues
MNIHEYQAKEVLHKFNVSVPKGFVATSAEEVKTQVSQLKSDVFVVKAQIHAGGRGKAGGVKLAKSAEEAQQFVKDMIGMT
LVTHQTGPSGQQVRKVYVEEGSSIKKEYYLSLVIDPKLSRPIFIFSSEGGMDIEEVAKNSPAKIVKFDIDSATSFDSSKL
SSSFHLSPEQIEKITNVAKNIYDAFIATDASQIEINPLVETSSGDFIALDAKINFDDNALYRHPEIMELRDYDEEVKEEI
EASKYGLSYIKMDGSIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFKIILSDSNVKGILVNIFGGIM
RCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKILEESGLNIIAADELGDAAQKIVKEVK
>Mature_383_residues
MNIHEYQAKEVLHKFNVSVPKGFVATSAEEVKTQVSQLKSDVFVVKAQIHAGGRGKAGGVKLAKSAEEAQQFVKDMIGMT
LVTHQTGPSGQQVRKVYVEEGSSIKKEYYLSLVIDPKLSRPIFIFSSEGGMDIEEVAKNSPAKIVKFDIDSATSFDSSKL
SSSFHLSPEQIEKITNVAKNIYDAFIATDASQIEINPLVETSSGDFIALDAKINFDDNALYRHPEIMELRDYDEEVKEEI
EASKYGLSYIKMDGSIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFKIILSDSNVKGILVNIFGGIM
RCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKILEESGLNIIAADELGDAAQKIVKEVK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=47.1794871794872, Blast_Score=354, Evalue=9e-98,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=44.9612403100775, Blast_Score=313, Evalue=1e-85,
Organism=Homo sapiens, GI294862256, Length=367, Percent_Identity=44.4141689373297, Blast_Score=295, Evalue=7e-80,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=48.9637305699482, Blast_Score=374, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17539378, Length=391, Percent_Identity=45.0127877237852, Blast_Score=336, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=43.7017994858612, Blast_Score=326, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=42.7480916030534, Blast_Score=341, Evalue=1e-94,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=45.974025974026, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=45.974025974026, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=46.3730569948187, Blast_Score=345, Evalue=4e-95,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=46.3730569948187, Blast_Score=345, Evalue=4e-95,
Organism=Drosophila melanogaster, GI21356231, Length=390, Percent_Identity=45.3846153846154, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI281363475, Length=340, Percent_Identity=25.2941176470588, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI281363473, Length=340, Percent_Identity=25.2941176470588, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI281363477, Length=340, Percent_Identity=25.2941176470588, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41555; Mature: 41555

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEVLHKFNVSVPKGFVATSAEEVKTQVSQLKSDVFVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCC
KLAKSAEEAQQFVKDMIGMTLVTHQTGPSGQQVRKVYVEEGSSIKKEYYLSLVIDPKLSR
HHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCC
PIFIFSSEGGMDIEEVAKNSPAKIVKFDIDSATSFDSSKLSSSFHLSPEQIEKITNVAKN
CEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
IYDAFIATDASQIEINPLVETSSGDFIALDAKINFDDNALYRHPEIMELRDYDEEVKEEI
HHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCEECCCCHHHHHCCHHHHHHHH
EASKYGLSYIKMDGSIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFK
HHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHH
IILSDSNVKGILVNIFGGIMRCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKILEE
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCHHHHHHHHHH
SGLNIIAADELGDAAQKIVKEVK
CCCEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKEVLHKFNVSVPKGFVATSAEEVKTQVSQLKSDVFVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCC
KLAKSAEEAQQFVKDMIGMTLVTHQTGPSGQQVRKVYVEEGSSIKKEYYLSLVIDPKLSR
HHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCC
PIFIFSSEGGMDIEEVAKNSPAKIVKFDIDSATSFDSSKLSSSFHLSPEQIEKITNVAKN
CEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
IYDAFIATDASQIEINPLVETSSGDFIALDAKINFDDNALYRHPEIMELRDYDEEVKEEI
HHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCEECCCCHHHHHCCHHHHHHHH
EASKYGLSYIKMDGSIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFK
HHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHH
IILSDSNVKGILVNIFGGIMRCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKILEE
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCHHHHHHHHHH
SGLNIIAADELGDAAQKIVKEVK
CCCEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA