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The map label for this gene is sucD [H]

Identifier: 225630875

GI number: 225630875

Start: 1278317

End: 1279192

Strand: Reverse

Name: sucD [H]

Synonym: WRi_011870

Alternate gene names: 225630875

Gene position: 1279192-1278317 (Counterclockwise)

Preceding gene: 225630876

Following gene: 225630872

Centisome position: 88.47

GC content: 41.78

Gene sequence:

>876_bases
ATGTCCGTTTTAGTAAACAAAGATACAAGATTAATATGCCAGGGTTTTACTGGTGCACAAGGCACATTTCATTCAGAGCA
AGCAATTGATTACGGAACGAAAATGGTGGGAGGTGTAACTCCTGGAAAGGGTGGTAGCACTCACCTTAATTTACCGGTTT
TTAATACTGTAGCAGAAGCCAAAGAAAAAACCGGTGCAAATGCTACAGTTATATATGTACCTGCTAAATTTGCTGCTGCT
GCAATACTTGAAGCAATAGATGCAAAAATAGAATTGATAATTTGTATTACAGAGGGCATTCCTATACTTGATATGGTGAA
AGTTAAGCGTGCGCTTATCGGCTCAAAAAGTCGATTGATTGGTCCCAACTGCCCGGGAATTATTACACCTGAAGAATGCA
AAATAGGAATTATGCCTGGCCATATCCATAAGCGTGGACACATAGGAATTATGTCTCGCTCCGGAACTTTAACTTACGAG
GCAGTAGCACAAACAACCGCTGTTGGTCTTGGTCAATCCACGTGTATCGGAATTGGGGGGGATCCAATTCATGGTATGAC
ATTTGTCGACTGTATGGAGCTCTTTTTAAAAGATAACGATACTCATGGTATTGTAGTTATTGGTGAAATAGGTGGAAACG
AAGAAGAAGATGTATCACATTTTGTGAAAGCAGAAAAAACTAAAAAGCCAATCGTTGGTTTTGTAGCAGGCCAAACGGCA
CCTCCAGGAAGACGTATGGGACACGCTGGAGCAATCATTTCTTCCAGCGGTGGAAGTGCTGGTGCAAAACTAGAAGTTAT
GCGGAGTGCCGGGATTGCAATTGCTGAAACCCCTGCAGTAATTGGTAAGAAGGTATTGGAAGTAATGCATCACTAG

Upstream 100 bases:

>100_bases
AGAAGGAAAAAAAATCTTAGAAGAGTCAGGATTAAATATTATTGCTGCAGATGAACTGGGTGATGCTGCACAAAAGATAG
TAAAAGAGGTAAAATAAAGC

Downstream 100 bases:

>100_bases
AATTAGGGTCACAAAAACCCTATATCACCGGTCATGAATACGTTATTTGCCCATTCGATTAATAACTTCCCTCCTGGTAA
ATTTACTGAAGTCTGTTGGA

Product: succinyl-CoA synthetase, alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEAKEKTGANATVIYVPAKFAAA
AILEAIDAKIELIICITEGIPILDMVKVKRALIGSKSRLIGPNCPGIITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYE
AVAQTTAVGLGQSTCIGIGGDPIHGMTFVDCMELFLKDNDTHGIVVIGEIGGNEEEDVSHFVKAEKTKKPIVGFVAGQTA
PPGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMHH

Sequences:

>Translated_291_residues
MSVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEAKEKTGANATVIYVPAKFAAA
AILEAIDAKIELIICITEGIPILDMVKVKRALIGSKSRLIGPNCPGIITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYE
AVAQTTAVGLGQSTCIGIGGDPIHGMTFVDCMELFLKDNDTHGIVVIGEIGGNEEEDVSHFVKAEKTKKPIVGFVAGQTA
PPGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMHH
>Mature_290_residues
SVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEAKEKTGANATVIYVPAKFAAAA
ILEAIDAKIELIICITEGIPILDMVKVKRALIGSKSRLIGPNCPGIITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYEA
VAQTTAVGLGQSTCIGIGGDPIHGMTFVDCMELFLKDNDTHGIVVIGEIGGNEEEDVSHFVKAEKTKKPIVGFVAGQTAP
PGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMHH

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=289, Percent_Identity=64.7058823529412, Blast_Score=337, Evalue=6e-93,
Organism=Homo sapiens, GI38569423, Length=260, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI38569421, Length=260, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=63.6678200692042, Blast_Score=368, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17553126, Length=285, Percent_Identity=62.8070175438596, Blast_Score=350, Evalue=5e-97,
Organism=Caenorhabditis elegans, GI17550194, Length=285, Percent_Identity=60, Blast_Score=342, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17557344, Length=259, Percent_Identity=27.7992277992278, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=259, Percent_Identity=27.7992277992278, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=49.3197278911565, Blast_Score=279, Evalue=3e-76,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=56.8493150684932, Blast_Score=339, Evalue=1e-93,
Organism=Drosophila melanogaster, GI28574296, Length=292, Percent_Identity=61.986301369863, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI281363477, Length=264, Percent_Identity=28.7878787878788, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281363475, Length=264, Percent_Identity=28.7878787878788, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281363473, Length=264, Percent_Identity=28.7878787878788, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30284; Mature: 30152

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEA
CCEEECCCCEEEEECCCCCCCCCCCHHHHHHCCHHHCCCCCCCCCCEEEECCHHHHHHHH
KEKTGANATVIYVPAKFAAAAILEAIDAKIELIICITEGIPILDMVKVKRALIGSKSRLI
HHHCCCCEEEEEECHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCC
GPNCPGIITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYEAVAQTTAVGLGQSTCIGIGG
CCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPIHGMTFVDCMELFLKDNDTHGIVVIGEIGGNEEEDVSHFVKAEKTKKPIVGFVAGQTA
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCC
PPGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMHH
CCCCCCCCCCEEEECCCCCCCCEEEEEHHCCEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEA
CEEECCCCEEEEECCCCCCCCCCCHHHHHHCCHHHCCCCCCCCCCEEEECCHHHHHHHH
KEKTGANATVIYVPAKFAAAAILEAIDAKIELIICITEGIPILDMVKVKRALIGSKSRLI
HHHCCCCEEEEEECHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCC
GPNCPGIITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYEAVAQTTAVGLGQSTCIGIGG
CCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPIHGMTFVDCMELFLKDNDTHGIVVIGEIGGNEEEDVSHFVKAEKTKKPIVGFVAGQTA
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCC
PPGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMHH
CCCCCCCCCCEEEECCCCCCCCEEEEEHHCCEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]