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The map label for this gene is pdxH [H]

Identifier: 225630829

GI number: 225630829

Start: 1223032

End: 1223625

Strand: Direct

Name: pdxH [H]

Synonym: WRi_011340

Alternate gene names: 225630829

Gene position: 1223032-1223625 (Clockwise)

Preceding gene: 225630828

Following gene: 225630830

Centisome position: 84.59

GC content: 35.19

Gene sequence:

>594_bases
ATGATATTTTCATCTGAAAAAGATCCGATTGATTTATTTTCAAAGTGGTATAAAGAAGTACTCAATTCGTCATATAGAGA
ACCAACTGCAATGACGCTAGCAACGTGTAGCAAAGACTGCATTCCATCTGCAAGAGTAGTATTACTAAAGGAATATAGTA
AAGAAGGTTTTGTGTTCTTCACTAACATAAATAGTAGAAAAGGAAAAGAATTGACCGAGAACCCTAAAGCTGCATTAGTG
TTTCACTGGATAGAATTTTCTAGGCAGGTAAGAATTGAAGGAGAGGTTAAACTCCTAAACAGTAAAAAAGCTGATGAATA
TTTCTCTTCTCGAGCACGTGATAGTCAAATTAGCGCATGGTGCTCAAAACAATCGAGCATTCTGAAAGATTGGCAAGATT
TTGAGCAAGCTATAAAATTAAAGGAAAAAGAATTTCACAATACACAAGTTTCTCGTCCTGACTTTTGGGTGGGATTTTGC
GTAATCCCAAAAGTAATTGAATTTTGGCAAGAAGGTGAATATAGGAAGCATATTAGATTTAGATACACTCTTGTTGAGGG
AAGCGATTGGAAAGTGGAACAACTATATCCTTAA

Upstream 100 bases:

>100_bases
CCTTGCAAGATTTGCAATAATATCATAACACTTATACGACAAAATGGCCGTAGCACTTATTTTTGCAACGCGTGCCAGAA
TTAAGATTTTATTTTTTGAT

Downstream 100 bases:

>100_bases
AAATGGTTGCGGGAGTAGGATTTGAACCTACGACCTTCAGGTTATGAGCCTGACGAGCTACCGAGCTGCTCCATCCCGCG
TCGTTGCTTATTTAGTTATT

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIFSSEKDPIDLFSKWYKEVLNSSYREPTAMTLATCSKDCIPSARVVLLKEYSKEGFVFFTNINSRKGKELTENPKAALV
FHWIEFSRQVRIEGEVKLLNSKKADEYFSSRARDSQISAWCSKQSSILKDWQDFEQAIKLKEKEFHNTQVSRPDFWVGFC
VIPKVIEFWQEGEYRKHIRFRYTLVEGSDWKVEQLYP

Sequences:

>Translated_197_residues
MIFSSEKDPIDLFSKWYKEVLNSSYREPTAMTLATCSKDCIPSARVVLLKEYSKEGFVFFTNINSRKGKELTENPKAALV
FHWIEFSRQVRIEGEVKLLNSKKADEYFSSRARDSQISAWCSKQSSILKDWQDFEQAIKLKEKEFHNTQVSRPDFWVGFC
VIPKVIEFWQEGEYRKHIRFRYTLVEGSDWKVEQLYP
>Mature_197_residues
MIFSSEKDPIDLFSKWYKEVLNSSYREPTAMTLATCSKDCIPSARVVLLKEYSKEGFVFFTNINSRKGKELTENPKAALV
FHWIEFSRQVRIEGEVKLLNSKKADEYFSSRARDSQISAWCSKQSSILKDWQDFEQAIKLKEKEFHNTQVSRPDFWVGFC
VIPKVIEFWQEGEYRKHIRFRYTLVEGSDWKVEQLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=205, Percent_Identity=42.4390243902439, Blast_Score=158, Evalue=4e-39,
Organism=Escherichia coli, GI1787926, Length=191, Percent_Identity=42.4083769633508, Blast_Score=155, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17553712, Length=179, Percent_Identity=38.5474860335196, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6319509, Length=199, Percent_Identity=37.6884422110553, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI45551845, Length=191, Percent_Identity=38.7434554973822, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24644901, Length=191, Percent_Identity=38.7434554973822, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24644903, Length=192, Percent_Identity=25, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 23320; Mature: 23320

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSSEKDPIDLFSKWYKEVLNSSYREPTAMTLATCSKDCIPSARVVLLKEYSKEGFVFF
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHEEEEEECCCCCEEEE
TNINSRKGKELTENPKAALVFHWIEFSRQVRIEGEVKLLNSKKADEYFSSRARDSQISAW
EECCCCCCCCCCCCCCCEEEEEEEHHCCEEEECCEEEEECCCCHHHHHHHHCCCHHHHHH
CSKQSSILKDWQDFEQAIKLKEKEFHNTQVSRPDFWVGFCVIPKVIEFWQEGEYRKHIRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
RYTLVEGSDWKVEQLYP
EEEEEECCCCCCCCCCC
>Mature Secondary Structure
MIFSSEKDPIDLFSKWYKEVLNSSYREPTAMTLATCSKDCIPSARVVLLKEYSKEGFVFF
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHEEEEEECCCCCEEEE
TNINSRKGKELTENPKAALVFHWIEFSRQVRIEGEVKLLNSKKADEYFSSRARDSQISAW
EECCCCCCCCCCCCCCCEEEEEEEHHCCEEEECCEEEEECCCCHHHHHHHHCCCHHHHHH
CSKQSSILKDWQDFEQAIKLKEKEFHNTQVSRPDFWVGFCVIPKVIEFWQEGEYRKHIRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
RYTLVEGSDWKVEQLYP
EEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA