| Definition | Wolbachia sp. wRi, complete genome. |
|---|---|
| Accession | NC_012416 |
| Length | 1,445,873 |
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The map label for this gene is polA [H]
Identifier: 225630667
GI number: 225630667
Start: 1023292
End: 1025868
Strand: Reverse
Name: polA [H]
Synonym: WRi_009520
Alternate gene names: 225630667
Gene position: 1025868-1023292 (Counterclockwise)
Preceding gene: 225630668
Following gene: 225630666
Centisome position: 70.95
GC content: 34.58
Gene sequence:
>2577_bases ATGAAAGAAAAAACTTTCACAATCATCGATGGCTATGGTTTTCTTTTCAGAGCTTACTATGTACTACCTCATTTAATTAC CACAACAGGAATGCCAATAGGTGGTGTATATGGCTTTCTGAATATGGTTCTTAAGTACATTGCCCATTCGGACTATTTAA CTATAGCACTTGATGCAGGAAAAAAGAATTTTAGGCACGATTTATATCCTGAGTACAAAGCGAACAGAGTAACGCCTCCT GAGGATCTAACTCCACAGTTTACCATACTGAGGGAAGCGGTAGAAGCTTTTAACCTCAGCTATGAAGAGATTGAAGGTTA TGAAGCAGATGATATAATCGCAACACTAGCTGCAAAATACGCCAACCACCAAGACTTTAAAGTGGTAGTCGTTTCATCAG ATAAAGATTTGTTCCAGCTTTTGAATTACAATATTCTAATATTTGATCCTATTAAAAATATATACATAGATGAAAAACAA ATAGTAGAAAAATTTGGTGTAAATTCAAACAAGCTTCTTGATTTATTTTCTCTAACTGGTGATGCATCTGATAACATTCC AGGCGTTCCAGGAATAGGCCCAAAAACTGCCACTAAATTATTAGATGAATTTGATTCATTGAATAATATTATAGAGAACA TTGATAACATCGAGCAAACGAGGATTCGTAATATTCTTGCTGAACATAAGGAAAAAGCGCTAATTTCAAGAGAACTTTTA TCACTATGCGAAAAAGTAGACCTTCAACATGATATTGCAAAATGTGAAGTTCGCCCTCCAAATATGGAAAAACTATTATC CTTTTTAAAGAAGTATGAATTCAATTCTTTAATAGGTAAAATGGAAAAGCTTTTTTCCTATAATGGGTCTAGCACAAAAG AGAAAATAGAATATAGTAGTGAAGAGTTAGAGAAATTTTTGGAGCATTGTAGATATGAAGGCAAAATTGCAATTCATTAC CACCTTGAAAACAATGTATTAAGTCTATCTTATAGCGAAAGTAATATTTTTTATATAGAGCAAGACAGCATACAAGATGC ACTTATTACAATTAACTCAACTTTACTCTCAAATGGAGTGCTTAAAATAATACATAACATTAAAGAGATCAGGAAAATCT TCCCTGCAACAGAGAAGATGTTAGATTCAGTTGATGATTTGATGATAATGTCGTATAGCTTGGATACAGGAAAACACGAT CACAGTATTCCAAACATAGTTGCGCATAATTTGAGTGAAAATGCAGAAATTTTCTCGGCAAAAACTTTAATAGCAATTCA TGAAAAGCTAAAGCAAAGGTTATTTCAGGAAAAATTGTTCACAATTTACGAGCGCTTCGATAAGCCACTTATGAAAGTAA TATTTGATATGGAGAAAAATGGGATATTACTGAACATACAAAAATTACAGGAGCTGTCCGATAAATTTCAGCAGGTAATT GCCGTGCTTGAAGATGAGATATATAATTTGGCAGGAGAAAGATTTAATATTGCTTCGCCAAAACAATTAAGTGATGTTTT ATTCAACAAAATGGGGCTTAATAAAAAGAAAAAGTCAAAAAAATCTGGATCGTATAGCACCAATTATGAAGTTCTAGAGG CACTCGAAGAAGAAGGGGTAGAAATCGCAAGTAAAATCTTAAATTGGCGACATTTAAGTAAATTAAAAGGCACCTACACT GATGCATTAATAAAGCAAGTTGATCCACTTGATGGTAGAATACACACAAGCTTTTCAACGACTGCAACTGCAACTGGAAG GCTGAGCTCCAGCAATCCTAATTTACAGAATATTCCTATCAGAAGCGAAGAGGGAAATCTTATCAGACAAGCATTTATTG CGCCAAAAGGGCATAAGATAATTTCTGCTGACTATTCACAAATAGAATTGAGACTCCTGGCACACGTTGCAAACGTTGCA GCATTTAAAGAAGCTTTTGCAAACGAACAAGATATTCACGATATCACCGCTAGGCAAGTTTTTGGAGTGCAAGAAATAGA TGAGCAATTAAGACGCAAAGCAAAATCCATTAATTTTGGAATTATATATGGCATTAGCCCATTTGGTCTTGCAAAGCGGC TTGGAATTACCATTGCGGAGGCTGCTGAATACATTAATTACTATTTTTCCTGTTACCCAGAAATAAAGGTCTATATGGAA AAAGCAGTGTCTATCGCAAGATTGCATGGTTATGTAGAAACTTTGTTTGGCAGGAGATGCTTTGTGAGAGACATAAATAA TACAATTCCTTATGTAAGACAATTTGCAGAAAGGGCAGCAATAAACGCACCACTGCAAGGCACCGCCGCTGATATAATAA AACGTGCGACGATTCAGCTTTTTGACCAATTAAAAGTAGGTAAAATAATCCTCCAGGTTCACGATGAACTACTGGTTGAA GTAGAAGACGAAAAGGTACAAGAAACAGCAAAACTTATGAAAGATATAATGGAAAATGCAATAGAAATTTCTGTACCACT TGAAGTAGAAATAAAAGTTGGCGACAACTGGGGTCTAAATTCCCTTAATTATGACTTAAACATCGTGAATTCTAGGAGTA TAAATCATTTGAACTAA
Upstream 100 bases:
>100_bases TTTTCGGTAAAATCTCTTACAACGCTCAAAAGCAGAAAAACAAAAACTTGATTTTCTCAGCTAAATAGTGGACCATCAAA AGCACGCATAAATATCTACA
Downstream 100 bases:
>100_bases TACGAAAAATATGTTAGAATAGAACATAGCAAATGCAAATAGGTCAGCCATGACAGGCCCACAAGTAAAAAGTTCAAAAC CTCCAAAGTTACCTACTCAG
Product: DNA polymerase I
Products: NA
Alternate protein names: POL I [H]
Number of amino acids: Translated: 858; Mature: 858
Protein sequence:
>858_residues MKEKTFTIIDGYGFLFRAYYVLPHLITTTGMPIGGVYGFLNMVLKYIAHSDYLTIALDAGKKNFRHDLYPEYKANRVTPP EDLTPQFTILREAVEAFNLSYEEIEGYEADDIIATLAAKYANHQDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYIDEKQ IVEKFGVNSNKLLDLFSLTGDASDNIPGVPGIGPKTATKLLDEFDSLNNIIENIDNIEQTRIRNILAEHKEKALISRELL SLCEKVDLQHDIAKCEVRPPNMEKLLSFLKKYEFNSLIGKMEKLFSYNGSSTKEKIEYSSEELEKFLEHCRYEGKIAIHY HLENNVLSLSYSESNIFYIEQDSIQDALITINSTLLSNGVLKIIHNIKEIRKIFPATEKMLDSVDDLMIMSYSLDTGKHD HSIPNIVAHNLSENAEIFSAKTLIAIHEKLKQRLFQEKLFTIYERFDKPLMKVIFDMEKNGILLNIQKLQELSDKFQQVI AVLEDEIYNLAGERFNIASPKQLSDVLFNKMGLNKKKKSKKSGSYSTNYEVLEALEEEGVEIASKILNWRHLSKLKGTYT DALIKQVDPLDGRIHTSFSTTATATGRLSSSNPNLQNIPIRSEEGNLIRQAFIAPKGHKIISADYSQIELRLLAHVANVA AFKEAFANEQDIHDITARQVFGVQEIDEQLRRKAKSINFGIIYGISPFGLAKRLGITIAEAAEYINYYFSCYPEIKVYME KAVSIARLHGYVETLFGRRCFVRDINNTIPYVRQFAERAAINAPLQGTAADIIKRATIQLFDQLKVGKIILQVHDELLVE VEDEKVQETAKLMKDIMENAIEISVPLEVEIKVGDNWGLNSLNYDLNIVNSRSINHLN
Sequences:
>Translated_858_residues MKEKTFTIIDGYGFLFRAYYVLPHLITTTGMPIGGVYGFLNMVLKYIAHSDYLTIALDAGKKNFRHDLYPEYKANRVTPP EDLTPQFTILREAVEAFNLSYEEIEGYEADDIIATLAAKYANHQDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYIDEKQ IVEKFGVNSNKLLDLFSLTGDASDNIPGVPGIGPKTATKLLDEFDSLNNIIENIDNIEQTRIRNILAEHKEKALISRELL SLCEKVDLQHDIAKCEVRPPNMEKLLSFLKKYEFNSLIGKMEKLFSYNGSSTKEKIEYSSEELEKFLEHCRYEGKIAIHY HLENNVLSLSYSESNIFYIEQDSIQDALITINSTLLSNGVLKIIHNIKEIRKIFPATEKMLDSVDDLMIMSYSLDTGKHD HSIPNIVAHNLSENAEIFSAKTLIAIHEKLKQRLFQEKLFTIYERFDKPLMKVIFDMEKNGILLNIQKLQELSDKFQQVI AVLEDEIYNLAGERFNIASPKQLSDVLFNKMGLNKKKKSKKSGSYSTNYEVLEALEEEGVEIASKILNWRHLSKLKGTYT DALIKQVDPLDGRIHTSFSTTATATGRLSSSNPNLQNIPIRSEEGNLIRQAFIAPKGHKIISADYSQIELRLLAHVANVA AFKEAFANEQDIHDITARQVFGVQEIDEQLRRKAKSINFGIIYGISPFGLAKRLGITIAEAAEYINYYFSCYPEIKVYME KAVSIARLHGYVETLFGRRCFVRDINNTIPYVRQFAERAAINAPLQGTAADIIKRATIQLFDQLKVGKIILQVHDELLVE VEDEKVQETAKLMKDIMENAIEISVPLEVEIKVGDNWGLNSLNYDLNIVNSRSINHLN >Mature_858_residues MKEKTFTIIDGYGFLFRAYYVLPHLITTTGMPIGGVYGFLNMVLKYIAHSDYLTIALDAGKKNFRHDLYPEYKANRVTPP EDLTPQFTILREAVEAFNLSYEEIEGYEADDIIATLAAKYANHQDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYIDEKQ IVEKFGVNSNKLLDLFSLTGDASDNIPGVPGIGPKTATKLLDEFDSLNNIIENIDNIEQTRIRNILAEHKEKALISRELL SLCEKVDLQHDIAKCEVRPPNMEKLLSFLKKYEFNSLIGKMEKLFSYNGSSTKEKIEYSSEELEKFLEHCRYEGKIAIHY HLENNVLSLSYSESNIFYIEQDSIQDALITINSTLLSNGVLKIIHNIKEIRKIFPATEKMLDSVDDLMIMSYSLDTGKHD HSIPNIVAHNLSENAEIFSAKTLIAIHEKLKQRLFQEKLFTIYERFDKPLMKVIFDMEKNGILLNIQKLQELSDKFQQVI AVLEDEIYNLAGERFNIASPKQLSDVLFNKMGLNKKKKSKKSGSYSTNYEVLEALEEEGVEIASKILNWRHLSKLKGTYT DALIKQVDPLDGRIHTSFSTTATATGRLSSSNPNLQNIPIRSEEGNLIRQAFIAPKGHKIISADYSQIELRLLAHVANVA AFKEAFANEQDIHDITARQVFGVQEIDEQLRRKAKSINFGIIYGISPFGLAKRLGITIAEAAEYINYYFSCYPEIKVYME KAVSIARLHGYVETLFGRRCFVRDINNTIPYVRQFAERAAINAPLQGTAADIIKRATIQLFDQLKVGKIILQVHDELLVE VEDEKVQETAKLMKDIMENAIEISVPLEVEIKVGDNWGLNSLNYDLNIVNSRSINHLN
Specific function: In addition to polymerase activity, this DNA polymerase 5' to 3' exonuclease activity [H]
COG id: COG0749
COG function: function code L; DNA polymerase I - 3'-5' exonuclease and polymerase domains
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 5'-3' exonuclease domain [H]
Homologues:
Organism=Homo sapiens, GI112420958, Length=471, Percent_Identity=30.5732484076433, Blast_Score=208, Evalue=2e-53, Organism=Homo sapiens, GI139394648, Length=534, Percent_Identity=27.1535580524345, Blast_Score=175, Evalue=2e-43, Organism=Escherichia coli, GI1790294, Length=924, Percent_Identity=35.8225108225108, Blast_Score=502, Evalue=1e-143, Organism=Escherichia coli, GI226510970, Length=190, Percent_Identity=40.5263157894737, Blast_Score=124, Evalue=3e-29, Organism=Caenorhabditis elegans, GI86563272, Length=399, Percent_Identity=30.3258145363409, Blast_Score=166, Evalue=4e-41, Organism=Drosophila melanogaster, GI17933644, Length=432, Percent_Identity=31.9444444444444, Blast_Score=206, Evalue=4e-53,
Paralogues:
None
Copy number: 400 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020046 - InterPro: IPR020045 - InterPro: IPR002421 - InterPro: IPR020047 - InterPro: IPR019760 - InterPro: IPR001098 - InterPro: IPR018320 - InterPro: IPR002298 - InterPro: IPR008918 - InterPro: IPR012337 [H]
Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; PF00476 DNA_pol_A [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 97707; Mature: 97707
Theoretical pI: Translated: 5.91; Mature: 5.91
Prosite motif: PS00447 DNA_POLYMERASE_A
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKEKTFTIIDGYGFLFRAYYVLPHLITTTGMPIGGVYGFLNMVLKYIAHSDYLTIALDAG CCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECC KKNFRHDLYPEYKANRVTPPEDLTPQFTILREAVEAFNLSYEEIEGYEADDIIATLAAKY CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHH ANHQDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYIDEKQIVEKFGVNSNKLLDLFSLTG CCCCCEEEEEEECCHHHHHHHCCCEEEECCCCHHCCCHHHHHHHHCCCCCHHHHHHHHCC DASDNIPGVPGIGPKTATKLLDEFDSLNNIIENIDNIEQTRIRNILAEHKEKALISRELL CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SLCEKVDLQHDIAKCEVRPPNMEKLLSFLKKYEFNSLIGKMEKLFSYNGSSTKEKIEYSS HHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCH EELEKFLEHCRYEGKIAIHYHLENNVLSLSYSESNIFYIEQDSIQDALITINSTLLSNGV HHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHH LKIIHNIKEIRKIFPATEKMLDSVDDLMIMSYSLDTGKHDHSIPNIVAHNLSENAEIFSA HHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHH KTLIAIHEKLKQRLFQEKLFTIYERFDKPLMKVIFDMEKNGILLNIQKLQELSDKFQQVI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH AVLEDEIYNLAGERFNIASPKQLSDVLFNKMGLNKKKKSKKSGSYSTNYEVLEALEEEGV HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHCCH EIASKILNWRHLSKLKGTYTDALIKQVDPLDGRIHTSFSTTATATGRLSSSNPNLQNIPI HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCC RSEEGNLIRQAFIAPKGHKIISADYSQIELRLLAHVANVAAFKEAFANEQDIHDITARQV CCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH FGVQEIDEQLRRKAKSINFGIIYGISPFGLAKRLGITIAEAAEYINYYFSCYPEIKVYME HCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHH KAVSIARLHGYVETLFGRRCFVRDINNTIPYVRQFAERAAINAPLQGTAADIIKRATIQL HHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH FDQLKVGKIILQVHDELLVEVEDEKVQETAKLMKDIMENAIEISVPLEVEIKVGDNWGLN HHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCEEEECCEEEEEEECCCCCCC SLNYDLNIVNSRSINHLN CCCCEEEEECCCCCCCCC >Mature Secondary Structure MKEKTFTIIDGYGFLFRAYYVLPHLITTTGMPIGGVYGFLNMVLKYIAHSDYLTIALDAG CCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECC KKNFRHDLYPEYKANRVTPPEDLTPQFTILREAVEAFNLSYEEIEGYEADDIIATLAAKY CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHH ANHQDFKVVVVSSDKDLFQLLNYNILIFDPIKNIYIDEKQIVEKFGVNSNKLLDLFSLTG CCCCCEEEEEEECCHHHHHHHCCCEEEECCCCHHCCCHHHHHHHHCCCCCHHHHHHHHCC DASDNIPGVPGIGPKTATKLLDEFDSLNNIIENIDNIEQTRIRNILAEHKEKALISRELL CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SLCEKVDLQHDIAKCEVRPPNMEKLLSFLKKYEFNSLIGKMEKLFSYNGSSTKEKIEYSS HHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCH EELEKFLEHCRYEGKIAIHYHLENNVLSLSYSESNIFYIEQDSIQDALITINSTLLSNGV HHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHH LKIIHNIKEIRKIFPATEKMLDSVDDLMIMSYSLDTGKHDHSIPNIVAHNLSENAEIFSA HHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHH KTLIAIHEKLKQRLFQEKLFTIYERFDKPLMKVIFDMEKNGILLNIQKLQELSDKFQQVI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH AVLEDEIYNLAGERFNIASPKQLSDVLFNKMGLNKKKKSKKSGSYSTNYEVLEALEEEGV HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHCCH EIASKILNWRHLSKLKGTYTDALIKQVDPLDGRIHTSFSTTATATGRLSSSNPNLQNIPI HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCC RSEEGNLIRQAFIAPKGHKIISADYSQIELRLLAHVANVAAFKEAFANEQDIHDITARQV CCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH FGVQEIDEQLRRKAKSINFGIIYGISPFGLAKRLGITIAEAAEYINYYFSCYPEIKVYME HCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHH KAVSIARLHGYVETLFGRRCFVRDINNTIPYVRQFAERAAINAPLQGTAADIIKRATIQL HHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH FDQLKVGKIILQVHDELLVEVEDEKVQETAKLMKDIMENAIEISVPLEVEIKVGDNWGLN HHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCEEEECCEEEEEEECCCCCCC SLNYDLNIVNSRSINHLN CCCCEEEEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA