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The map label for this gene is gpsA [H]

Identifier: 225630494

GI number: 225630494

Start: 808255

End: 809238

Strand: Direct

Name: gpsA [H]

Synonym: WRi_007450

Alternate gene names: 225630494

Gene position: 808255-809238 (Clockwise)

Preceding gene: 225630492

Following gene: 225630495

Centisome position: 55.9

GC content: 35.87

Gene sequence:

>984_bases
GTGGCAATATCAATTTTAGGTGCTGGTGCATGGGGTACAGCAATCGCAATTTCATTAGGTAGTAAGAAAGATGTGATTTT
GTGGACTCGCAATGAAACTACATTTGAATCAATCAACGGGAAAAGAGAAAGTGACAAGCTACCCGGTTGTCGAATTTCTG
ATAATGTGTCAGTAAAATTGGCTATTGAAGACACAATTAATGCTTCAGTAACAATCCTCGCTGTTCCCACTCAGTCTCTG
AGGAAGGTATGTCAGCAATTGCATAATTGTAATCTGAAAAAAGATGTAGCAATAATTTTAGCTTGTAAGGGAATAGAAAA
GTCTACATTAAAATTACCTAGTGAAATAGTAAATGAAATTTTACCTAACAATCCTATTGCTATTTTTTCAGGTCCTAGCT
TTGCTGTAGAAGTTGCAAGAAAATTACCCTATTCAATGGTTCTTGCATGCCAAAATAACACATTAGGTTCAAAGCTAGTA
TCAGAGCTGCAACAAGAAAATGTTAAATTGGAGTTTAGTAACGACATTATAGGAGTACAGATTTGTGCAGCGTTAAAGAA
CGTTTTTGCTATAGCGTGTGGGATTGTTCTAGGTAGTAAACTTGGGTTTAATGCTCATGCAGCATTGATTACGAAAAGTA
TGAGCGAAATTAAGGCTTTATACTCAGCAAAAATTGGTGACGGTAGTGTGGATATAAATACACTACTTGGGCCAGCATGT
CTGGGTGACCTAATTATGACATGCACATCCTTGAATTCAAGAAACTTATCTTTTGGGTTTAAAATAGGTAATAGTGACAA
TGGCTTTAATGTTCAGCAGATTTTGTCAGAAGGCAAGTCAGTGATTGAAGGTTTTAGCACTGCTGAGTCCATATTTAATT
TAGCAGGAAAGCTAAAGATAAAAATGCCTATATGTGAAGCGGTCTATAGATTATTGTATGAAAGCGCCTCTATAGAGGAT
ACTATTTCTGTTCTTATAAGTTAA

Upstream 100 bases:

>100_bases
TCGGTTAATAAATATTTAACTATTCTATATGTCTGTGTTATATTTTTAATTTACTTATCCTACTATTTTAAAGTATAAGT
AATATTTTCAGGAATATTGT

Downstream 100 bases:

>100_bases
TTTTGTATTTGGATATATTGTGAAATTTTTATATAAATTAATATCAACGTGGTGGCTGTCTGGAACAGTAAAAAAAATGC
CAGGTACTGTGGGTAGTTTG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAISILGAGAWGTAIAISLGSKKDVILWTRNETTFESINGKRESDKLPGCRISDNVSVKLAIEDTINASVTILAVPTQSL
RKVCQQLHNCNLKKDVAIILACKGIEKSTLKLPSEIVNEILPNNPIAIFSGPSFAVEVARKLPYSMVLACQNNTLGSKLV
SELQQENVKLEFSNDIIGVQICAALKNVFAIACGIVLGSKLGFNAHAALITKSMSEIKALYSAKIGDGSVDINTLLGPAC
LGDLIMTCTSLNSRNLSFGFKIGNSDNGFNVQQILSEGKSVIEGFSTAESIFNLAGKLKIKMPICEAVYRLLYESASIED
TISVLIS

Sequences:

>Translated_327_residues
MAISILGAGAWGTAIAISLGSKKDVILWTRNETTFESINGKRESDKLPGCRISDNVSVKLAIEDTINASVTILAVPTQSL
RKVCQQLHNCNLKKDVAIILACKGIEKSTLKLPSEIVNEILPNNPIAIFSGPSFAVEVARKLPYSMVLACQNNTLGSKLV
SELQQENVKLEFSNDIIGVQICAALKNVFAIACGIVLGSKLGFNAHAALITKSMSEIKALYSAKIGDGSVDINTLLGPAC
LGDLIMTCTSLNSRNLSFGFKIGNSDNGFNVQQILSEGKSVIEGFSTAESIFNLAGKLKIKMPICEAVYRLLYESASIED
TISVLIS
>Mature_326_residues
AISILGAGAWGTAIAISLGSKKDVILWTRNETTFESINGKRESDKLPGCRISDNVSVKLAIEDTINASVTILAVPTQSLR
KVCQQLHNCNLKKDVAIILACKGIEKSTLKLPSEIVNEILPNNPIAIFSGPSFAVEVARKLPYSMVLACQNNTLGSKLVS
ELQQENVKLEFSNDIIGVQICAALKNVFAIACGIVLGSKLGFNAHAALITKSMSEIKALYSAKIGDGSVDINTLLGPACL
GDLIMTCTSLNSRNLSFGFKIGNSDNGFNVQQILSEGKSVIEGFSTAESIFNLAGKLKIKMPICEAVYRLLYESASIEDT
ISVLIS

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=344, Percent_Identity=29.0697674418605, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI24307999, Length=359, Percent_Identity=27.0194986072423, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1790037, Length=317, Percent_Identity=33.7539432176656, Blast_Score=171, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17507425, Length=342, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32564399, Length=332, Percent_Identity=29.2168674698795, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=341, Percent_Identity=28.7390029325513, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI193210136, Length=341, Percent_Identity=28.7390029325513, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI193210134, Length=328, Percent_Identity=26.219512195122, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324513, Length=355, Percent_Identity=25.9154929577465, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17136204, Length=345, Percent_Identity=26.9565217391304, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17136200, Length=345, Percent_Identity=26.9565217391304, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17136202, Length=345, Percent_Identity=26.9565217391304, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362270, Length=234, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45551945, Length=234, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648969, Length=193, Percent_Identity=27.979274611399, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 34930; Mature: 34799

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISILGAGAWGTAIAISLGSKKDVILWTRNETTFESINGKRESDKLPGCRISDNVSVKL
CEEEEEECCCCCEEEEEEECCCCCEEEEECCCCHHHHCCCCCCCCCCCCCEECCCCEEEE
AIEDTINASVTILAVPTQSLRKVCQQLHNCNLKKDVAIILACKGIEKSTLKLPSEIVNEI
EEECCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHCCCHHHHHHH
LPNNPIAIFSGPSFAVEVARKLPYSMVLACQNNTLGSKLVSELQQENVKLEFSNDIIGVQ
CCCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCHHHH
ICAALKNVFAIACGIVLGSKLGFNAHAALITKSMSEIKALYSAKIGDGSVDINTLLGPAC
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHH
LGDLIMTCTSLNSRNLSFGFKIGNSDNGFNVQQILSEGKSVIEGFSTAESIFNLAGKLKI
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCEEE
KMPICEAVYRLLYESASIEDTISVLIS
ECHHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
AISILGAGAWGTAIAISLGSKKDVILWTRNETTFESINGKRESDKLPGCRISDNVSVKL
EEEEEECCCCCEEEEEEECCCCCEEEEECCCCHHHHCCCCCCCCCCCCCEECCCCEEEE
AIEDTINASVTILAVPTQSLRKVCQQLHNCNLKKDVAIILACKGIEKSTLKLPSEIVNEI
EEECCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHCCCHHHHHHH
LPNNPIAIFSGPSFAVEVARKLPYSMVLACQNNTLGSKLVSELQQENVKLEFSNDIIGVQ
CCCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCHHHH
ICAALKNVFAIACGIVLGSKLGFNAHAALITKSMSEIKALYSAKIGDGSVDINTLLGPAC
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHH
LGDLIMTCTSLNSRNLSFGFKIGNSDNGFNVQQILSEGKSVIEGFSTAESIFNLAGKLKI
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCEEE
KMPICEAVYRLLYESASIEDTISVLIS
ECHHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA