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The map label for this gene is xerC [H]

Identifier: 225630477

GI number: 225630477

Start: 784436

End: 785356

Strand: Reverse

Name: xerC [H]

Synonym: WRi_007250

Alternate gene names: 225630477

Gene position: 785356-784436 (Counterclockwise)

Preceding gene: 225630478

Following gene: 225630475

Centisome position: 54.32

GC content: 36.05

Gene sequence:

>921_bases
GTGGACCTCGGTTCAATCATTGAAAAATGGTATGAGTGGCTGAGGTGCAACAGATCTTATTCACCAAATACTTTAGAGTC
ATACATGAGGGACTTGAAGGATCTTATAAGTTTCCTAAATACTCACATTGGCGGAGAAGTAAATGTTGGTACTCTGAAAA
ATTTAAGCATACCTGAGTTAAGAAGTTGGCTTACCTCTCGTTACGCAAGAGGTGTAAACGCAAGATCCAACACTCGAGCA
CTCTCAGTAATCAGAAATTTCTTCAAGTACATAAAAAATAACCACAATATAGACAATGAAGCTGTATTTTCCTTATCAAG
GCCAATTCAGAGAAGAACTCTGCCCAAAGCATTATCAATACCTAATATAAAAACTTTATTGAAAGAAATGAAACTATCCG
ACCTGGGTGAACCTTGGGTGGTAAAAAGAGAAATTGCGATTATCGTCCTGCTATATGGTACAGGCTTAAGAATCAGTGAA
GCGTTGAACCTTAGGGTTAGTGATATTAACAATGAAAGTTTAATAGTAACAGGTAAAGGAGATAAACAAAGGCAGGTATT
CATTCTCCCCGTAGTAAAAAAATGTATACAAGAGTATATAAAAGCTTGCCCTTACCTTGATGAAGCACAACATCTTTTTG
TGGGAGTAAGAGGAAAAAAATTGGGAAGAACTTATGTGGCCAATCGTTTGCAGAAAATAAGGAGAATGTTAAATTTACCA
GAAATTTTATCTCCACATGCATTTCGTCATAGTTTTGCTACTCATTTGCTTCAGGAAGATATTGACATAAGATCAATACA
ACAACTGCTTGGTCACTCAAGCCTGGAAACTACTCAAATTTACACTCACCTCAATTATCAAGATGTTTTTAACATGTACA
AAAATTTTCAGCAGGGCCTGGAGAAGAAATCAAAACTTTAA

Upstream 100 bases:

>100_bases
GCGCAGCAGCAGAGGATATATACAGAATTTGTCACTCTCATCCTGATATAAATGAAGCCTTTCGAGATGCGTGCATCGAT
GCTTTCTTTAAAAAATAATT

Downstream 100 bases:

>100_bases
CTTCGTTCTAAACCACCAAGCTGAGTGCTTTCAACATCACTAAGTATTGTGTTTGCTTTATATAAATTACAACATCCTAA
TAAAAAAAAAGCCAGTGCAA

Product: site-specific recombinase, phage integrase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDLGSIIEKWYEWLRCNRSYSPNTLESYMRDLKDLISFLNTHIGGEVNVGTLKNLSIPELRSWLTSRYARGVNARSNTRA
LSVIRNFFKYIKNNHNIDNEAVFSLSRPIQRRTLPKALSIPNIKTLLKEMKLSDLGEPWVVKREIAIIVLLYGTGLRISE
ALNLRVSDINNESLIVTGKGDKQRQVFILPVVKKCIQEYIKACPYLDEAQHLFVGVRGKKLGRTYVANRLQKIRRMLNLP
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQIYTHLNYQDVFNMYKNFQQGLEKKSKL

Sequences:

>Translated_306_residues
MDLGSIIEKWYEWLRCNRSYSPNTLESYMRDLKDLISFLNTHIGGEVNVGTLKNLSIPELRSWLTSRYARGVNARSNTRA
LSVIRNFFKYIKNNHNIDNEAVFSLSRPIQRRTLPKALSIPNIKTLLKEMKLSDLGEPWVVKREIAIIVLLYGTGLRISE
ALNLRVSDINNESLIVTGKGDKQRQVFILPVVKKCIQEYIKACPYLDEAQHLFVGVRGKKLGRTYVANRLQKIRRMLNLP
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQIYTHLNYQDVFNMYKNFQQGLEKKSKL
>Mature_306_residues
MDLGSIIEKWYEWLRCNRSYSPNTLESYMRDLKDLISFLNTHIGGEVNVGTLKNLSIPELRSWLTSRYARGVNARSNTRA
LSVIRNFFKYIKNNHNIDNEAVFSLSRPIQRRTLPKALSIPNIKTLLKEMKLSDLGEPWVVKREIAIIVLLYGTGLRISE
ALNLRVSDINNESLIVTGKGDKQRQVFILPVVKKCIQEYIKACPYLDEAQHLFVGVRGKKLGRTYVANRLQKIRRMLNLP
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQIYTHLNYQDVFNMYKNFQQGLEKKSKL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=30.8474576271186, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=32.0945945945946, Blast_Score=131, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35443; Mature: 35443

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGSIIEKWYEWLRCNRSYSPNTLESYMRDLKDLISFLNTHIGGEVNVGTLKNLSIPEL
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
RSWLTSRYARGVNARSNTRALSVIRNFFKYIKNNHNIDNEAVFSLSRPIQRRTLPKALSI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHCCCHHCCC
PNIKTLLKEMKLSDLGEPWVVKREIAIIVLLYGTGLRISEALNLRVSDINNESLIVTGKG
CCHHHHHHHHHHHHCCCCCEEEHHEEEEEEEECCCCEEHHHHEEEEEECCCCEEEEECCC
DKQRQVFILPVVKKCIQEYIKACPYLDEAQHLFVGVRGKKLGRTYVANRLQKIRRMLNLP
CCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHCCH
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQIYTHLNYQDVFNMYKNFQQGL
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
EKKSKL
HHHCCC
>Mature Secondary Structure
MDLGSIIEKWYEWLRCNRSYSPNTLESYMRDLKDLISFLNTHIGGEVNVGTLKNLSIPEL
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
RSWLTSRYARGVNARSNTRALSVIRNFFKYIKNNHNIDNEAVFSLSRPIQRRTLPKALSI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHCCCHHCCC
PNIKTLLKEMKLSDLGEPWVVKREIAIIVLLYGTGLRISEALNLRVSDINNESLIVTGKG
CCHHHHHHHHHHHHCCCCCEEEHHEEEEEEEECCCCEEHHHHEEEEEECCCCEEEEECCC
DKQRQVFILPVVKKCIQEYIKACPYLDEAQHLFVGVRGKKLGRTYVANRLQKIRRMLNLP
CCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHCCH
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQIYTHLNYQDVFNMYKNFQQGL
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
EKKSKL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]