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The map label for this gene is dapD [H]

Identifier: 225630420

GI number: 225630420

Start: 706974

End: 707804

Strand: Direct

Name: dapD [H]

Synonym: WRi_006550

Alternate gene names: 225630420

Gene position: 706974-707804 (Clockwise)

Preceding gene: 225630417

Following gene: 225630423

Centisome position: 48.9

GC content: 36.58

Gene sequence:

>831_bases
ATGGAAGGTTTGCAACTAAAAAAAACACAGAGTGAGATAAAAGATATTTGGAAAAATAGAGAAAAATTTAATGACTGTAA
TCTAAAGAAAACAGCAAGAATAGCAATTAAAGAGGTAATTGAGCTCCTTGATAGTGGCAAAATTAGAGTAGCAGAAAAGC
TATCAAGTGGAGAATGGGTAGTACATAAGTGGATAAAGCAGGCAATATTATTACATTTTCTCACCGAAGAAAATAAAATA
ATAGATAATACTAATTGCTGGTTTGATAAGATCGGTAACAAGTTTAGTGAATGGAATGAGGAGAAATTTCGCCGGTTAAA
AATTAGAGCAGTTCCTGGGTGTTTTGTTCGCCGATCTGCTTATATAGGTACAAATGTTGTTCTAATGCCAAGTTTTATCA
ACGTTGGTGCATATGTTGATTCAGGAACAATGATAGATACCTGGTCAACGATTGGTAGCTGTGCGCAAATAGGAAAAAAC
TGTCATATTTCCGGTGGAGTGGGAATAGGTGGAGTTCTTGAGCCTATTCAAGCTTCACCTGTCATTATAGAAGATAATTG
CTTTATTGGAGCACGTAGCGAAGTGGCCGAGGGTGTGGTAGTGAGAGAAGGATCAGTCCTTGGCATAGGCGTGTTTATTG
GGGCATCAACAAAGATTATTGATAGAGAAACTAGCAAGGTATTTTACGGCGAAGTGCCACCTTATTCTGTAGTGGTACCA
GGGTCTATTCCATCTAAAAATAATATTTCAACCTATTGTGCAGTCATAGTAAAAAAAGTGGATGAAAAGACGAGATCGAA
AATCTCTATAAATGAAATATTGAGGGATTAA

Upstream 100 bases:

>100_bases
TACAATTATAACATTGTATTTTCATAGTACTTACGTATAAAGTAGTAACAAGCTTAAATGATACAGAGCTACAAATTTAA
TATCAATATATATATAACAA

Downstream 100 bases:

>100_bases
ACTATCTCACTGCTTGTCGTCACTTTTTTTATCATTATTACTAACCACAGTAATGGCATAAGCGCATAACTCTGAGAAAG
AGACTCCATTTTCTTGAGAT

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MEGLQLKKTQSEIKDIWKNREKFNDCNLKKTARIAIKEVIELLDSGKIRVAEKLSSGEWVVHKWIKQAILLHFLTEENKI
IDNTNCWFDKIGNKFSEWNEEKFRRLKIRAVPGCFVRRSAYIGTNVVLMPSFINVGAYVDSGTMIDTWSTIGSCAQIGKN
CHISGGVGIGGVLEPIQASPVIIEDNCFIGARSEVAEGVVVREGSVLGIGVFIGASTKIIDRETSKVFYGEVPPYSVVVP
GSIPSKNNISTYCAVIVKKVDEKTRSKISINEILRD

Sequences:

>Translated_276_residues
MEGLQLKKTQSEIKDIWKNREKFNDCNLKKTARIAIKEVIELLDSGKIRVAEKLSSGEWVVHKWIKQAILLHFLTEENKI
IDNTNCWFDKIGNKFSEWNEEKFRRLKIRAVPGCFVRRSAYIGTNVVLMPSFINVGAYVDSGTMIDTWSTIGSCAQIGKN
CHISGGVGIGGVLEPIQASPVIIEDNCFIGARSEVAEGVVVREGSVLGIGVFIGASTKIIDRETSKVFYGEVPPYSVVVP
GSIPSKNNISTYCAVIVKKVDEKTRSKISINEILRD
>Mature_276_residues
MEGLQLKKTQSEIKDIWKNREKFNDCNLKKTARIAIKEVIELLDSGKIRVAEKLSSGEWVVHKWIKQAILLHFLTEENKI
IDNTNCWFDKIGNKFSEWNEEKFRRLKIRAVPGCFVRRSAYIGTNVVLMPSFINVGAYVDSGTMIDTWSTIGSCAQIGKN
CHISGGVGIGGVLEPIQASPVIIEDNCFIGARSEVAEGVVVREGSVLGIGVFIGASTKIIDRETSKVFYGEVPPYSVVVP
GSIPSKNNISTYCAVIVKKVDEKTRSKISINEILRD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=272, Percent_Identity=56.25, Blast_Score=304, Evalue=3e-84,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005664
- InterPro:   IPR023180
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.117 [H]

Molecular weight: Translated: 30652; Mature: 30652

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGLQLKKTQSEIKDIWKNREKFNDCNLKKTARIAIKEVIELLDSGKIRVAEKLSSGEWV
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
VHKWIKQAILLHFLTEENKIIDNTNCWFDKIGNKFSEWNEEKFRRLKIRAVPGCFVRRSA
HHHHHHHHHHHHHHHCCCCEECCCCCHHHHHCCHHHHCCHHHHHEEEEEECCCHHHHHHH
YIGTNVVLMPSFINVGAYVDSGTMIDTWSTIGSCAQIGKNCHISGGVGIGGVLEPIQASP
HCCCCEEEECCHHCCCEEECCCCEEECHHHHHHHHHHCCCEEECCCCCCCCHHCCCCCCC
VIIEDNCFIGARSEVAEGVVVREGSVLGIGVFIGASTKIIDRETSKVFYGEVPPYSVVVP
EEEECCCEECCHHHHHCCEEEECCCEEEEEEEECCCEEEEECCCCEEEECCCCCEEEEEC
GSIPSKNNISTYCAVIVKKVDEKTRSKISINEILRD
CCCCCCCCHHHHHHHHHHHHHHHHHHCEEHHHHHCC
>Mature Secondary Structure
MEGLQLKKTQSEIKDIWKNREKFNDCNLKKTARIAIKEVIELLDSGKIRVAEKLSSGEWV
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
VHKWIKQAILLHFLTEENKIIDNTNCWFDKIGNKFSEWNEEKFRRLKIRAVPGCFVRRSA
HHHHHHHHHHHHHHHCCCCEECCCCCHHHHHCCHHHHCCHHHHHEEEEEECCCHHHHHHH
YIGTNVVLMPSFINVGAYVDSGTMIDTWSTIGSCAQIGKNCHISGGVGIGGVLEPIQASP
HCCCCEEEECCHHCCCEEECCCCEEECHHHHHHHHHHCCCEEECCCCCCCCHHCCCCCCC
VIIEDNCFIGARSEVAEGVVVREGSVLGIGVFIGASTKIIDRETSKVFYGEVPPYSVVVP
EEEECCCEECCHHHHHCCEEEECCCEEEEEEEECCCEEEEECCCCEEEECCCCCEEEEEC
GSIPSKNNISTYCAVIVKKVDEKTRSKISINEILRD
CCCCCCCCHHHHHHHHHHHHHHHHHHCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA