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The map label for this gene is ribD [H]

Identifier: 225630417

GI number: 225630417

Start: 702984

End: 704066

Strand: Direct

Name: ribD [H]

Synonym: WRi_006500

Alternate gene names: 225630417

Gene position: 702984-704066 (Clockwise)

Preceding gene: 225630416

Following gene: 225630420

Centisome position: 48.62

GC content: 37.58

Gene sequence:

>1083_bases
ATGACTGATGATCATTTCATGTCAATTGCATTAAGGCTTGCAGAAAAAAATCTTGGAAATGTTGCACCAAATCCTGCTGT
CGGGTGTGTTATTGTAAAGGATGGTACAATTGTTAGTGAGGGATACACAGGGATTGGTGGGCGTCCGCATGCGGAGGTAG
TCGCTTTGCAAAACGCTAAAGATTCAACTCATGGCGCAACTATATATATCACTCTTGAGCCATGTTGTCATCACGGAGTC
ACGGGGCCTTGCACTGCAAAAATCATAAAAGCTAGCATAAAAAGAGTAGTAATTGCAACTATTGACCCAGATAGTAGAGT
TTCAGGCAGAGGCATGAAAGCTCTGAAAGAAGCAGGAATTGAAGTTGAGCAAGGTATTATGCAAAAAGAGGCAAAAGAAC
TGAATGTCGGTTTTTTCACCACTAAAGAATTACATAGACCATTTATAGCTTGCAAAGTCGCAACAACTCTTGACGGAAAA
ATCGCAACATTTACAGGCGATAGCAAATGGATAACAAGTGAAAATACGAGAAACTGGGTGCATGAGCTCAGAACGAAATA
TGATGCAATTATGATCGGCAGCAATACTCTTATTAATGATGATCCACTCTTAACTTGCAGATTACCAGGACTTGGAAGTA
GATCGCCAATAAGGCTAATTATAGATAGCCAAGGGAGATTAAAGGAAGAGCATAACATTGCAAAGACTGCAGACAAAGTA
ATAACTTGGGTCATCACAAATAAAGAAGTAGAGAAAAAAATAAAAAACATTAACTACTTAGTAGTTAATTCAAGCAACGC
AGGTAAGGTTTGCCTAAAGGACATGGCATTAAAACTTGTTTCAGAAATTGGTATAACAAGATTATTAGTTGAAGGTGGAG
GAGTGTTAATCACAGAACTATTAAAGTGTAATTTAATCGACAGGTTGATAATATGCCGCAGTGGTAAAATTTTAGGCAAT
GATGCCACTCCTTTTGTAGGAGATTTAGGGATTCAATTCATTAACAACTGTTATCAGTTTAAAAAAACAAAGATAATAGA
GTTTAGTGAGGATATAGTTGAGGTTTGGGATAGGTCGTCATAA

Upstream 100 bases:

>100_bases
CAGTAATAATATGTGACTATATCTCAGGTATGACAGATAGATTTGCTATACACGAGCACAGAAGAATTTTTGATACCTCA
TACGAAATGACTTCTTTCTA

Downstream 100 bases:

>100_bases
TCCTTACATACTCAAACAGTAAAAAAAAGGTATCCGTTCAGCGGAGCGGTAAAATAAAAAGTAGACAAGGAGTGCTAAAA
ACATAATATCACAAGTAGTA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTDDHFMSIALRLAEKNLGNVAPNPAVGCVIVKDGTIVSEGYTGIGGRPHAEVVALQNAKDSTHGATIYITLEPCCHHGV
TGPCTAKIIKASIKRVVIATIDPDSRVSGRGMKALKEAGIEVEQGIMQKEAKELNVGFFTTKELHRPFIACKVATTLDGK
IATFTGDSKWITSENTRNWVHELRTKYDAIMIGSNTLINDDPLLTCRLPGLGSRSPIRLIIDSQGRLKEEHNIAKTADKV
ITWVITNKEVEKKIKNINYLVVNSSNAGKVCLKDMALKLVSEIGITRLLVEGGGVLITELLKCNLIDRLIICRSGKILGN
DATPFVGDLGIQFINNCYQFKKTKIIEFSEDIVEVWDRSS

Sequences:

>Translated_360_residues
MTDDHFMSIALRLAEKNLGNVAPNPAVGCVIVKDGTIVSEGYTGIGGRPHAEVVALQNAKDSTHGATIYITLEPCCHHGV
TGPCTAKIIKASIKRVVIATIDPDSRVSGRGMKALKEAGIEVEQGIMQKEAKELNVGFFTTKELHRPFIACKVATTLDGK
IATFTGDSKWITSENTRNWVHELRTKYDAIMIGSNTLINDDPLLTCRLPGLGSRSPIRLIIDSQGRLKEEHNIAKTADKV
ITWVITNKEVEKKIKNINYLVVNSSNAGKVCLKDMALKLVSEIGITRLLVEGGGVLITELLKCNLIDRLIICRSGKILGN
DATPFVGDLGIQFINNCYQFKKTKIIEFSEDIVEVWDRSS
>Mature_359_residues
TDDHFMSIALRLAEKNLGNVAPNPAVGCVIVKDGTIVSEGYTGIGGRPHAEVVALQNAKDSTHGATIYITLEPCCHHGVT
GPCTAKIIKASIKRVVIATIDPDSRVSGRGMKALKEAGIEVEQGIMQKEAKELNVGFFTTKELHRPFIACKVATTLDGKI
ATFTGDSKWITSENTRNWVHELRTKYDAIMIGSNTLINDDPLLTCRLPGLGSRSPIRLIIDSQGRLKEEHNIAKTADKVI
TWVITNKEVEKKIKNINYLVVNSSNAGKVCLKDMALKLVSEIGITRLLVEGGGVLITELLKCNLIDRLIICRSGKILGND
ATPFVGDLGIQFINNCYQFKKTKIIEFSEDIVEVWDRSS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=363, Percent_Identity=38.2920110192837, Blast_Score=254, Evalue=5e-69,
Organism=Saccharomyces cerevisiae, GI6319629, Length=186, Percent_Identity=27.9569892473118, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39411; Mature: 39280

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDHFMSIALRLAEKNLGNVAPNPAVGCVIVKDGTIVSEGYTGIGGRPHAEVVALQNAK
CCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEEEEECCC
DSTHGATIYITLEPCCHHGVTGPCTAKIIKASIKRVVIATIDPDSRVSGRGMKALKEAGI
CCCCCEEEEEEECHHHCCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHCCC
EVEQGIMQKEAKELNVGFFTTKELHRPFIACKVATTLDGKIATFTGDSKWITSENTRNWV
HHHHHHHHHHHHHCCCCEEEHHHHCCCEEEEEEEEECCCEEEEEECCCCEEECCCHHHHH
HELRTKYDAIMIGSNTLINDDPLLTCRLPGLGSRSPIRLIIDSQGRLKEEHNIAKTADKV
HHHHHHHCEEEECCCCEECCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHE
ITWVITNKEVEKKIKNINYLVVNSSNAGKVCLKDMALKLVSEIGITRLLVEGGGVLITEL
EEEEEECHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
LKCNLIDRLIICRSGKILGNDATPFVGDLGIQFINNCYQFKKTKIIEFSEDIVEVWDRSS
HHHHHHHHEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHCCCC
>Mature Secondary Structure 
TDDHFMSIALRLAEKNLGNVAPNPAVGCVIVKDGTIVSEGYTGIGGRPHAEVVALQNAK
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEEEEECCC
DSTHGATIYITLEPCCHHGVTGPCTAKIIKASIKRVVIATIDPDSRVSGRGMKALKEAGI
CCCCCEEEEEEECHHHCCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHCCC
EVEQGIMQKEAKELNVGFFTTKELHRPFIACKVATTLDGKIATFTGDSKWITSENTRNWV
HHHHHHHHHHHHHCCCCEEEHHHHCCCEEEEEEEEECCCEEEEEECCCCEEECCCHHHHH
HELRTKYDAIMIGSNTLINDDPLLTCRLPGLGSRSPIRLIIDSQGRLKEEHNIAKTADKV
HHHHHHHCEEEECCCCEECCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHE
ITWVITNKEVEKKIKNINYLVVNSSNAGKVCLKDMALKLVSEIGITRLLVEGGGVLITEL
EEEEEECHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
LKCNLIDRLIICRSGKILGNDATPFVGDLGIQFINNCYQFKKTKIIEFSEDIVEVWDRSS
HHHHHHHHEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]