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The map label for this gene is udg [H]

Identifier: 225630359

GI number: 225630359

Start: 625749

End: 627056

Strand: Reverse

Name: udg [H]

Synonym: WRi_005820

Alternate gene names: 225630359

Gene position: 627056-625749 (Counterclockwise)

Preceding gene: 225630360

Following gene: 225630349

Centisome position: 43.37

GC content: 33.18

Gene sequence:

>1308_bases
ATGTATATAACCATTATAGGAATAGGGTATGTAGGTTTAGTATCTTGTGCAATGTTATCAGAGCAGGGTCATAACGTTGA
TTGCATTGACATAAATACTAAGAAGATTGAGTTATTGAAATTAGGAAAAATTCCTATATATGAGCCTGGATTAGCAGACT
ATTTAGAGAATAATATAAAGTTACAAAGGATAAGATTCTTCGATTCGTATTCTCAAATAAATCCCAACACAGAAGTAGTG
TTTGTAACTGTAGATACTCCATCAGACTCCCTAGGAAATGCAAATTTACAGAATGTATATAATGCAGTAAGTGAAGTTTC
TGAGAGAGTTAATCAAGATTGCTTAATAGTGATAAAGTCAACTGTTCCTCCTGGTACTGCAGAAAATATATATAATTATT
TATCTAATAAGGGCTATAACTTTGATTTGGGGGTTAATCCAGAGTTTCTCAAGCAAGGCTCTGCAGTATCAGATTTTTTA
TACCCAGATAGGATAATAATAGGAGTAAAAACTAAGCTAGCTAGAGCAAAACTAGAAGTTATATATAGATCATTTATAGA
TAAGAATATTCCGTTAATAGTCACTGATACAGTTACTGCTGAAATGATTAAATATGCTTCTAATGCTTTTCTAGCAACAA
AGGTTGCTTTTATCAATGAGATGGCAGGTTTATGTGAGCTATTAGGAGCAGACATTGACCTTTTAGCTAACAGTATGGGA
ATGGACCATAGAATAGGTAAGGAATTTCTCAAAGCTGGTCCAGGATTTGGAGGATCATGTTTTCCTAAAGATTTGTCAGC
TTTAATAAGGCTTGCTGAAGATCACAATGTCAAGCTACAAATTTTAAATTCAGTTAAGGAATCTAACTATAATCATATAA
CAAACATTGCTAAAAAGGTAGAATATGTATTAAATGGAGTCCAAAATAAAAAAATAGCAATATGGGGGCTAACTTTTAAG
TCTGGTACTGATGATGTAAGAAATAGCCCAGCTATAGATATTGCACAATTGTTAGTGAATAACAAGGCTAAAATTACTGC
ATATGACCCAATGGGGATGGATAATGCTAGGCAAGTTCTAAAGGATATAGAATACGCGGACAATGCTATAGGGGCTGCAA
GGGACGCGGAAGCCTTGTTATTGTTAACGGAGTGGAAAGAATTTAAAAATCAAGATTTTGCAAGTTTAAAGAGTATTATG
GCTGCACCTAATGTTTTTGATTTCCGTAATTTATTAGATAGCGAGCTATTACTAAGATATGGTTACCATGTTTATTCCTT
GGGTAAAAAATCTATCTACAAAGTTTAA

Upstream 100 bases:

>100_bases
AACGCTAGAGTAAAAATTTATGACTCTAATTGTTAATGATGTTCTTTTTAAATGTTTAAGCAGTTGAGCTACATTAGGAT
ATTTTTAAGGTGATGACAAG

Downstream 100 bases:

>100_bases
CTGTTGAGAAATTTTTTTTACACCGCTTTACTTAGTTTTTTTAGATCTTTGCTTGATAGTATGGAAAAGCAAACGAGTGC
AACAACAGAGCAAATGGAAA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MYITIIGIGYVGLVSCAMLSEQGHNVDCIDINTKKIELLKLGKIPIYEPGLADYLENNIKLQRIRFFDSYSQINPNTEVV
FVTVDTPSDSLGNANLQNVYNAVSEVSERVNQDCLIVIKSTVPPGTAENIYNYLSNKGYNFDLGVNPEFLKQGSAVSDFL
YPDRIIIGVKTKLARAKLEVIYRSFIDKNIPLIVTDTVTAEMIKYASNAFLATKVAFINEMAGLCELLGADIDLLANSMG
MDHRIGKEFLKAGPGFGGSCFPKDLSALIRLAEDHNVKLQILNSVKESNYNHITNIAKKVEYVLNGVQNKKIAIWGLTFK
SGTDDVRNSPAIDIAQLLVNNKAKITAYDPMGMDNARQVLKDIEYADNAIGAARDAEALLLLTEWKEFKNQDFASLKSIM
AAPNVFDFRNLLDSELLLRYGYHVYSLGKKSIYKV

Sequences:

>Translated_435_residues
MYITIIGIGYVGLVSCAMLSEQGHNVDCIDINTKKIELLKLGKIPIYEPGLADYLENNIKLQRIRFFDSYSQINPNTEVV
FVTVDTPSDSLGNANLQNVYNAVSEVSERVNQDCLIVIKSTVPPGTAENIYNYLSNKGYNFDLGVNPEFLKQGSAVSDFL
YPDRIIIGVKTKLARAKLEVIYRSFIDKNIPLIVTDTVTAEMIKYASNAFLATKVAFINEMAGLCELLGADIDLLANSMG
MDHRIGKEFLKAGPGFGGSCFPKDLSALIRLAEDHNVKLQILNSVKESNYNHITNIAKKVEYVLNGVQNKKIAIWGLTFK
SGTDDVRNSPAIDIAQLLVNNKAKITAYDPMGMDNARQVLKDIEYADNAIGAARDAEALLLLTEWKEFKNQDFASLKSIM
AAPNVFDFRNLLDSELLLRYGYHVYSLGKKSIYKV
>Mature_435_residues
MYITIIGIGYVGLVSCAMLSEQGHNVDCIDINTKKIELLKLGKIPIYEPGLADYLENNIKLQRIRFFDSYSQINPNTEVV
FVTVDTPSDSLGNANLQNVYNAVSEVSERVNQDCLIVIKSTVPPGTAENIYNYLSNKGYNFDLGVNPEFLKQGSAVSDFL
YPDRIIIGVKTKLARAKLEVIYRSFIDKNIPLIVTDTVTAEMIKYASNAFLATKVAFINEMAGLCELLGADIDLLANSMG
MDHRIGKEFLKAGPGFGGSCFPKDLSALIRLAEDHNVKLQILNSVKESNYNHITNIAKKVEYVLNGVQNKKIAIWGLTFK
SGTDDVRNSPAIDIAQLLVNNKAKITAYDPMGMDNARQVLKDIEYADNAIGAARDAEALLLLTEWKEFKNQDFASLKSIM
AAPNVFDFRNLLDSELLLRYGYHVYSLGKKSIYKV

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=461, Percent_Identity=31.8872017353579, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI296040438, Length=363, Percent_Identity=33.0578512396694, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI296040443, Length=308, Percent_Identity=34.0909090909091, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1788340, Length=356, Percent_Identity=28.6516853932584, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI48994968, Length=363, Percent_Identity=26.4462809917355, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17560350, Length=458, Percent_Identity=32.7510917030568, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI17136908, Length=465, Percent_Identity=33.7634408602151, Blast_Score=251, Evalue=8e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48327; Mature: 48327

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYITIIGIGYVGLVSCAMLSEQGHNVDCIDINTKKIELLKLGKIPIYEPGLADYLENNIK
CEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCCHHHHHHCCCE
LQRIRFFDSYSQINPNTEVVFVTVDTPSDSLGNANLQNVYNAVSEVSERVNQDCLIVIKS
EEEEEEEHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEC
TVPPGTAENIYNYLSNKGYNFDLGVNPEFLKQGSAVSDFLYPDRIIIGVKTKLARAKLEV
CCCCCCHHHHHHHHHCCCCEEECCCCHHHHHCCCCHHHHCCCCEEEEEEHHHHHHHHHHH
IYRSFIDKNIPLIVTDTVTAEMIKYASNAFLATKVAFINEMAGLCELLGADIDLLANSMG
HHHHHHCCCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
MDHRIGKEFLKAGPGFGGSCFPKDLSALIRLAEDHNVKLQILNSVKESNYNHITNIAKKV
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHHHHH
EYVLNGVQNKKIAIWGLTFKSGTDDVRNSPAIDIAQLLVNNKAKITAYDPMGMDNARQVL
HHHHCCCCCCEEEEEEEEECCCCCHHCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
KDIEYADNAIGAARDAEALLLLTEWKEFKNQDFASLKSIMAAPNVFDFRNLLDSELLLRY
HHHHHHHHHCCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GYHVYSLGKKSIYKV
CCHHEECCCHHHCCC
>Mature Secondary Structure
MYITIIGIGYVGLVSCAMLSEQGHNVDCIDINTKKIELLKLGKIPIYEPGLADYLENNIK
CEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCCHHHHHHCCCE
LQRIRFFDSYSQINPNTEVVFVTVDTPSDSLGNANLQNVYNAVSEVSERVNQDCLIVIKS
EEEEEEEHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEC
TVPPGTAENIYNYLSNKGYNFDLGVNPEFLKQGSAVSDFLYPDRIIIGVKTKLARAKLEV
CCCCCCHHHHHHHHHCCCCEEECCCCHHHHHCCCCHHHHCCCCEEEEEEHHHHHHHHHHH
IYRSFIDKNIPLIVTDTVTAEMIKYASNAFLATKVAFINEMAGLCELLGADIDLLANSMG
HHHHHHCCCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
MDHRIGKEFLKAGPGFGGSCFPKDLSALIRLAEDHNVKLQILNSVKESNYNHITNIAKKV
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHHHHH
EYVLNGVQNKKIAIWGLTFKSGTDDVRNSPAIDIAQLLVNNKAKITAYDPMGMDNARQVL
HHHHCCCCCCEEEEEEEEECCCCCHHCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
KDIEYADNAIGAARDAEALLLLTEWKEFKNQDFASLKSIMAAPNVFDFRNLLDSELLLRY
HHHHHHHHHCCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GYHVYSLGKKSIYKV
CCHHEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274032; 9823893 [H]