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The map label for this gene is uhpC [H]

Identifier: 225630358

GI number: 225630358

Start: 624586

End: 625731

Strand: Direct

Name: uhpC [H]

Synonym: WRi_005810

Alternate gene names: 225630358

Gene position: 624586-625731 (Clockwise)

Preceding gene: 225630357

Following gene: 225630366

Centisome position: 43.2

GC content: 30.98

Gene sequence:

>1146_bases
ATGCTGCTTTATTTATCAAGACAAAGTATACCAATTGCTCTACCACTGTTAATAGATACTGACCATGTAAAATTAAGCTA
TTTTTTTGCCTGCTTTTCTTTTTTTTATGGAGTATCAAAATTTGTTAATGGAATAATCATGGACTCCAAAAATAATCCAT
TATTTATGTTTGGGCTATGCAATATTGCAACTGGATTATTAACCATTGGTATAACTTTATCATATAATAATCTAACTTTA
TTACTGTTAACATTAATATTATTAGCTTGGACACAAGGGTTAGGTTGGCCAGCTATTACCAAGTTTATGGTTACAAACTC
TAGCATCTCTTCAATTGCATCATCATGGGGAGTTATGAGCGCATCTCAGCAACTTGGTTCTTGTATTACTTTAATTGTAT
TACCAAGTATAATTAAAATATATAATGCAAAAAGTGCATTTTTGTACTCTGGTTTCTTATGCTTACTTTTTGGAATTTAT
ATAATATTAAAGGCATATTACAAAGAAAGTGCCAACTTTACTACCTATTATAAGGTGCAGAAATCTCAAATAGGTATCAA
GGTAACAAGTTCCATATGGTTTCTATGTTGTGCTACTTTTTGTGCTTATATTATAAAAATGGGAATCTTCTTTTGGTTTC
CTATAATTTTAAAGAATAAATTACAAATTTCTCTTGTACAATCCTCACTAATAACAGGCGTATATGATTTAGGTGGAATC
CTTGGAACTTTAATAACAGGAAGAATTAGTGATATGTACTTCTTTCAAAATAGAAGCTTGCTGGCATCACTTTATATGTT
GGGTATAGCACTCACTTTTATTGCAATGAACTTTGGTCAAAACATAATTCTTATGAACCTTTGTGCAATCTTATCAGGAT
TCTTTATATTTGGAGTGCAAGTACTGACAGGTGTTATAGCTGTAGAAATTGCTCCACAAAATAATGTATGTGCAATTGTA
AGCTTAACAGGATTATTTGGGTATATTGCAAGTTCAATATTTTCATGCGTGCTCTTAGGAGTACTTGTTAAGCACTGTGG
TAACAGTATTATGTTTTCATTTTTTTCCATTTGCTCTGTTGTTGCACTCGTTTGCTTTTCCATACTATCAAGCAAAGATC
TAAAAAAACTAAGTAAAGCGGTGTAA

Upstream 100 bases:

>100_bases
ATTATACCAATATAGTATTATGCTAGCATCTGCATAGAGCTATTTGGGAATAGGTGTGAACTTTGTCTTCTTTCAATATT
TACTATTCTTCTGTGGATAT

Downstream 100 bases:

>100_bases
AAAAAATTTCTCAACAGTTAAACTTTGTAGATAGATTTTTTACCCAAGGAATAAACATGGTAACCATATCTTAGTAATAG
CTCGCTATCTAATAAATTAC

Product: Major facilitator family transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MLLYLSRQSIPIALPLLIDTDHVKLSYFFACFSFFYGVSKFVNGIIMDSKNNPLFMFGLCNIATGLLTIGITLSYNNLTL
LLLTLILLAWTQGLGWPAITKFMVTNSSISSIASSWGVMSASQQLGSCITLIVLPSIIKIYNAKSAFLYSGFLCLLFGIY
IILKAYYKESANFTTYYKVQKSQIGIKVTSSIWFLCCATFCAYIIKMGIFFWFPIILKNKLQISLVQSSLITGVYDLGGI
LGTLITGRISDMYFFQNRSLLASLYMLGIALTFIAMNFGQNIILMNLCAILSGFFIFGVQVLTGVIAVEIAPQNNVCAIV
SLTGLFGYIASSIFSCVLLGVLVKHCGNSIMFSFFSICSVVALVCFSILSSKDLKKLSKAV

Sequences:

>Translated_381_residues
MLLYLSRQSIPIALPLLIDTDHVKLSYFFACFSFFYGVSKFVNGIIMDSKNNPLFMFGLCNIATGLLTIGITLSYNNLTL
LLLTLILLAWTQGLGWPAITKFMVTNSSISSIASSWGVMSASQQLGSCITLIVLPSIIKIYNAKSAFLYSGFLCLLFGIY
IILKAYYKESANFTTYYKVQKSQIGIKVTSSIWFLCCATFCAYIIKMGIFFWFPIILKNKLQISLVQSSLITGVYDLGGI
LGTLITGRISDMYFFQNRSLLASLYMLGIALTFIAMNFGQNIILMNLCAILSGFFIFGVQVLTGVIAVEIAPQNNVCAIV
SLTGLFGYIASSIFSCVLLGVLVKHCGNSIMFSFFSICSVVALVCFSILSSKDLKKLSKAV
>Mature_381_residues
MLLYLSRQSIPIALPLLIDTDHVKLSYFFACFSFFYGVSKFVNGIIMDSKNNPLFMFGLCNIATGLLTIGITLSYNNLTL
LLLTLILLAWTQGLGWPAITKFMVTNSSISSIASSWGVMSASQQLGSCITLIVLPSIIKIYNAKSAFLYSGFLCLLFGIY
IILKAYYKESANFTTYYKVQKSQIGIKVTSSIWFLCCATFCAYIIKMGIFFWFPIILKNKLQISLVQSSLITGVYDLGGI
LGTLITGRISDMYFFQNRSLLASLYMLGIALTFIAMNFGQNIILMNLCAILSGFFIFGVQVLTGVIAVEIAPQNNVCAIV
SLTGLFGYIASSIFSCVLLGVLVKHCGNSIMFSFFSICSVVALVCFSILSSKDLKKLSKAV

Specific function: Transport protein for sugar phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=426, Percent_Identity=23.2394366197183, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4503847, Length=426, Percent_Identity=23.2394366197183, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI256219483, Length=426, Percent_Identity=23.2394366197183, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788573, Length=407, Percent_Identity=26.5356265356265, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082310, Length=388, Percent_Identity=25, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI2367259, Length=274, Percent_Identity=26.2773722627737, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41868; Mature: 41868

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLYLSRQSIPIALPLLIDTDHVKLSYFFACFSFFYGVSKFVNGIIMDSKNNPLFMFGLC
CEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEEEHH
NIATGLLTIGITLSYNNLTLLLLTLILLAWTQGLGWPAITKFMVTNSSISSIASSWGVMS
HHHHHHHHHEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCHHH
ASQQLGSCITLIVLPSIIKIYNAKSAFLYSGFLCLLFGIYIILKAYYKESANFTTYYKVQ
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
KSQIGIKVTSSIWFLCCATFCAYIIKMGIFFWFPIILKNKLQISLVQSSLITGVYDLGGI
HHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LGTLITGRISDMYFFQNRSLLASLYMLGIALTFIAMNFGQNIILMNLCAILSGFFIFGVQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VLTGVIAVEIAPQNNVCAIVSLTGLFGYIASSIFSCVLLGVLVKHCGNSIMFSFFSICSV
HHHHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VALVCFSILSSKDLKKLSKAV
HHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MLLYLSRQSIPIALPLLIDTDHVKLSYFFACFSFFYGVSKFVNGIIMDSKNNPLFMFGLC
CEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEEEHH
NIATGLLTIGITLSYNNLTLLLLTLILLAWTQGLGWPAITKFMVTNSSISSIASSWGVMS
HHHHHHHHHEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCHHH
ASQQLGSCITLIVLPSIIKIYNAKSAFLYSGFLCLLFGIYIILKAYYKESANFTTYYKVQ
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
KSQIGIKVTSSIWFLCCATFCAYIIKMGIFFWFPIILKNKLQISLVQSSLITGVYDLGGI
HHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LGTLITGRISDMYFFQNRSLLASLYMLGIALTFIAMNFGQNIILMNLCAILSGFFIFGVQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VLTGVIAVEIAPQNNVCAIVSLTGLFGYIASSIFSCVLLGVLVKHCGNSIMFSFFSICSV
HHHHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VALVCFSILSSKDLKKLSKAV
HHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]