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The map label for this gene is glmU [H]

Identifier: 225630350

GI number: 225630350

Start: 613789

End: 614550

Strand: Direct

Name: glmU [H]

Synonym: WRi_005730

Alternate gene names: 225630350

Gene position: 613789-614550 (Clockwise)

Preceding gene: 225630348

Following gene: 225630351

Centisome position: 42.45

GC content: 32.15

Gene sequence:

>762_bases
ATGGATAACACGTTGATAATATTAGCAGCAGGAAAAAGCAGTAGAATGAATTCACAGTACTCAAAAACACTACACCTAGT
AGGAAATTTTACTCTTTTAGAGCATATAATTCACAATGCAAAACCGCTGAGTTTAAAAAGTCTATCAATTGTCATTAGCA
AGCCTTTTCTAAAGGAGTTAGAAAGATTTAGTACCTTAAAAGATATAATTGATAAATATAATATAAAATTGATAATTCAA
GAAAATATTACAGGTACTGGCACTGCAGTTAAAATTGCCCTAGAAAGCCTGGAGCGGTTATCTGACCAAGACATAGTTTT
AATACAGTACGGAGACACCCCGTTTATATCTAGTGATACAGTTATGAGAATGACTGATTGTTTAAAGTGTAATAATAAAA
ATTTAGTTCTTCTTGGATTTAATAGTCAAGATAAGCAATATGGAAGATTAGTAATTGATGATAATGACAATGTTCAAAAA
GTCTTGAAAAGTGAAGATGAAATTCTTCTTGCAAACTCTGGAATAATGGTTTCATACGCTAAAGATCTTTATACCCTAAT
AAAAGAAGTAAAATTTAATGATTCGACCAACGAATGTTGTCTTAATGATATAATACCCATTGCAGCAAGCAATAACTTAC
GTGCAGGTTATGTAGTCGCTGACGAAAAGGAAGCAATGGGGGTAAATAACAAAGAGGATTTGGTCAAAGCAGAACGTTAT
TTTCAGGCAAATAGAAGAAGACAACCAACCCTTCTTTCATAA

Upstream 100 bases:

>100_bases
ATGTTAATTATTTTTTCTGGATCATTTAGGAAACTATAGTAGACTTTACAACTCATTAATTATCACTTAACTTACCTCCT
AGTAAGTTCTTGAGTTATGT

Downstream 100 bases:

>100_bases
CTATATTTTTTTATTCATTGATCCTTAATTTAAGTTGACATTTGTTTTATACTAGTTTTATAATGCTTTTTAAGTCTTAC
TTGTAAGATGATAGGTGTGA

Product: UDP-N-acetylglucosamine pyrophosphorylase-related protein

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MDNTLIILAAGKSSRMNSQYSKTLHLVGNFTLLEHIIHNAKPLSLKSLSIVISKPFLKELERFSTLKDIIDKYNIKLIIQ
ENITGTGTAVKIALESLERLSDQDIVLIQYGDTPFISSDTVMRMTDCLKCNNKNLVLLGFNSQDKQYGRLVIDDNDNVQK
VLKSEDEILLANSGIMVSYAKDLYTLIKEVKFNDSTNECCLNDIIPIAASNNLRAGYVVADEKEAMGVNNKEDLVKAERY
FQANRRRQPTLLS

Sequences:

>Translated_253_residues
MDNTLIILAAGKSSRMNSQYSKTLHLVGNFTLLEHIIHNAKPLSLKSLSIVISKPFLKELERFSTLKDIIDKYNIKLIIQ
ENITGTGTAVKIALESLERLSDQDIVLIQYGDTPFISSDTVMRMTDCLKCNNKNLVLLGFNSQDKQYGRLVIDDNDNVQK
VLKSEDEILLANSGIMVSYAKDLYTLIKEVKFNDSTNECCLNDIIPIAASNNLRAGYVVADEKEAMGVNNKEDLVKAERY
FQANRRRQPTLLS
>Mature_253_residues
MDNTLIILAAGKSSRMNSQYSKTLHLVGNFTLLEHIIHNAKPLSLKSLSIVISKPFLKELERFSTLKDIIDKYNIKLIIQ
ENITGTGTAVKIALESLERLSDQDIVLIQYGDTPFISSDTVMRMTDCLKCNNKNLVLLGFNSQDKQYGRLVIDDNDNVQK
VLKSEDEILLANSGIMVSYAKDLYTLIKEVKFNDSTNECCLNDIIPIAASNNLRAGYVVADEKEAMGVNNKEDLVKAERY
FQANRRRQPTLLS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=250, Percent_Identity=26, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR001228
- InterPro:   IPR011004 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 28465; Mature: 28465

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNTLIILAAGKSSRMNSQYSKTLHLVGNFTLLEHIIHNAKPLSLKSLSIVISKPFLKEL
CCCEEEEEECCCCCCCCHHHHHEEHHHCCHHHHHHHHHCCCCCCEEEEEEEECCHHHHHH
ERFSTLKDIIDKYNIKLIIQENITGTGTAVKIALESLERLSDQDIVLIQYGDTPFISSDT
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCH
VMRMTDCLKCNNKNLVLLGFNSQDKQYGRLVIDDNDNVQKVLKSEDEILLANSGIMVSYA
HHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCHHHHHHCCCCCEEEECCCEEEEHH
KDLYTLIKEVKFNDSTNECCLNDIIPIAASNNLRAGYVVADEKEAMGVNNKEDLVKAERY
HHHHHHHHHHCCCCCCCCHHHHCCEEEECCCCCCEEEEEECCHHHCCCCCHHHHHHHHHH
FQANRRRQPTLLS
HHHCCCCCCCCCC
>Mature Secondary Structure
MDNTLIILAAGKSSRMNSQYSKTLHLVGNFTLLEHIIHNAKPLSLKSLSIVISKPFLKEL
CCCEEEEEECCCCCCCCHHHHHEEHHHCCHHHHHHHHHCCCCCCEEEEEEEECCHHHHHH
ERFSTLKDIIDKYNIKLIIQENITGTGTAVKIALESLERLSDQDIVLIQYGDTPFISSDT
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCH
VMRMTDCLKCNNKNLVLLGFNSQDKQYGRLVIDDNDNVQKVLKSEDEILLANSGIMVSYA
HHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCHHHHHHCCCCCEEEECCCEEEEHH
KDLYTLIKEVKFNDSTNECCLNDIIPIAASNNLRAGYVVADEKEAMGVNNKEDLVKAERY
HHHHHHHHHHCCCCCCCCHHHHCCEEEECCCCCCEEEEEECCHHHCCCCCHHHHHHHHHH
FQANRRRQPTLLS
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA