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The map label for this gene is dcd

Identifier: 225630207

GI number: 225630207

Start: 442972

End: 443529

Strand: Reverse

Name: dcd

Synonym: WRi_004100

Alternate gene names: 225630207

Gene position: 443529-442972 (Counterclockwise)

Preceding gene: 225630209

Following gene: 225630206

Centisome position: 30.68

GC content: 36.56

Gene sequence:

>558_bases
ATGGCAGTTATGCCAGATAAATGGATAAGAGAAAAAGCTGAAAATTTTGGAATGATAGAACCTTTTGTGAATCACAAAAG
CAGCAAAGGTGTTATATCTTTCGGACTATCATCTTATGGTTACGATGCAAGAGTGGATAATAAATTTAAAATTTTTACTA
ATGTTAATTCAGCTATCGTGGACCCTAAAAATTTTTCTGAGAATAGTTTCATAGATAAGGAAACAGACGTATGCATAATT
CCACCAAATAGCTTTGTGCTTGCAAGCACAGTGGAATATTTTCGTATACCAAGGAATGTACTGGTCATTTGTGTTGGTAA
ATCAACTTACGCAAGATGTGGAATTATAGTAAACGTTACTCCCTTAGAACCTGGATGGGAAGGTCATGTCACACTCGAAT
TCTCAAACACTACTCCGCTTCCTGCAAAAATTTACGCCAATGAAGGCGCATGCCAATTCGTATTTTTAAGCGGCGAAAGT
GAGTGTGAGAAATCATATGATGATATGAAAGGAAAATATATGAATCAGCATGGTATCACTTTGCCGCTGGTGAAGTGA

Upstream 100 bases:

>100_bases
GATCAAACTGAAAAGCTTTAATTGCATGACAAAAGCTACAGTTTACATTTAAATTTTATTTCATATTATTGTAAGTATTA
CACAACTTTAAGGAACAGTT

Downstream 100 bases:

>100_bases
TTGCCATGAGAGTGGTAATTTTTCACTTCCGCACTTTTTCATTGTTGCTTACAATAATTATAGCTACACCATGTGCTTTT
CTTAATTAAAAACTTCAATT

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MAVMPDKWIREKAENFGMIEPFVNHKSSKGVISFGLSSYGYDARVDNKFKIFTNVNSAIVDPKNFSENSFIDKETDVCII
PPNSFVLASTVEYFRIPRNVLVICVGKSTYARCGIIVNVTPLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFVFLSGES
ECEKSYDDMKGKYMNQHGITLPLVK

Sequences:

>Translated_185_residues
MAVMPDKWIREKAENFGMIEPFVNHKSSKGVISFGLSSYGYDARVDNKFKIFTNVNSAIVDPKNFSENSFIDKETDVCII
PPNSFVLASTVEYFRIPRNVLVICVGKSTYARCGIIVNVTPLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFVFLSGES
ECEKSYDDMKGKYMNQHGITLPLVK
>Mature_184_residues
AVMPDKWIREKAENFGMIEPFVNHKSSKGVISFGLSSYGYDARVDNKFKIFTNVNSAIVDPKNFSENSFIDKETDVCIIP
PNSFVLASTVEYFRIPRNVLVICVGKSTYARCGIIVNVTPLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFVFLSGESE
CEKSYDDMKGKYMNQHGITLPLVK

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=154, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_WOLPM (Q73I07)

Other databases:

- EMBL:   AE017196
- RefSeq:   NP_966171.1
- ProteinModelPortal:   Q73I07
- SMR:   Q73I07
- EnsemblBacteria:   EBWOLT00000004678
- GeneID:   2737899
- GenomeReviews:   AE017196_GR
- KEGG:   wol:WD0379
- TIGR:   WD_0379
- GeneTree:   EBGT00050000031024
- HOGENOM:   HBG553199
- OMA:   MEYFRIP
- PhylomeDB:   Q73I07
- ProtClustDB:   PRK00416
- BioCyc:   WPIP955:WD_0379-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 20693; Mature: 20562

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVMPDKWIREKAENFGMIEPFVNHKSSKGVISFGLSSYGYDARVDNKFKIFTNVNSAIV
CCCCCHHHHHHHHHCCCCCCHHHCCCCCCCEEEECCCCCCCCCEECCEEEEEEECCCEEE
DPKNFSENSFIDKETDVCIIPPNSFVLASTVEYFRIPRNVLVICVGKSTYARCGIIVNVT
CCCCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHCCCCEEEEEEECCCCCCEEEEEEEEE
PLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFVFLSGESECEKSYDDMKGKYMNQHGIT
ECCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCCEECCCCCE
LPLVK
EEEEC
>Mature Secondary Structure 
AVMPDKWIREKAENFGMIEPFVNHKSSKGVISFGLSSYGYDARVDNKFKIFTNVNSAIV
CCCCHHHHHHHHHCCCCCCHHHCCCCCCCEEEECCCCCCCCCEECCEEEEEEECCCEEE
DPKNFSENSFIDKETDVCIIPPNSFVLASTVEYFRIPRNVLVICVGKSTYARCGIIVNVT
CCCCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHCCCCEEEEEEECCCCCCEEEEEEEEE
PLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFVFLSGESECEKSYDDMKGKYMNQHGIT
ECCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCCEECCCCCE
LPLVK
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA