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The map label for this gene is argD [H]

Identifier: 225630183

GI number: 225630183

Start: 406127

End: 407305

Strand: Reverse

Name: argD [H]

Synonym: WRi_003790

Alternate gene names: 225630183

Gene position: 407305-406127 (Counterclockwise)

Preceding gene: 225630185

Following gene: 225630182

Centisome position: 28.17

GC content: 36.9

Gene sequence:

>1179_bases
ATGGATCATGTTGTTAATGCGTATAATAGACTTGACACTCCTATAGTCAGGGGAGAAGGGGCATATCTTTTTGATAAAGA
TGGTAAAAAATATTTAGATTTTGCTGCAGGTATTTCTACAACTTCTTTAGGGCATTGTCATCCATACATTACAGATAAGC
TGAAAGAGCAATCGAGCTCATTATGGCACTGCTCTAACATTTTCACTATTCCCGAGCAAGAAAGGCTTGCCGAGCGTTTA
ACAACCCTGACTTTTGCAGATAAAGTTTTTTTCTGCTCAAGTGGGCTTGAAGCAACAGAAGCTGCAATTAAGTTTATTCG
TCGTTACTTTTATTCAAAAGGGCAAGCAAAACGTAATCGTATTATTACAATTGAAGGAGGCTTTCATGGCCGCAGTATTG
CTGCAATTTCTGCTGGAGGCAATGAAAAATCACGCGAAGGTTTTGCTCCGCTCCTTTCTGGTTTTGATAAAGTGCCAAGA
AATGACATTAAAGCATTAGAAGAAAAAATCAACAATGAAATAGCTGCTGTATTTTTAGAGCCCATACAAAGCGAAGGTGG
AGTATATCCACTAGACGTAGAATATCTTCAAAAAGTAAGGGAAATAACAAAAGCTCAAGGAATAATTTTGTGCTTTGATG
AAGTGCAGTGCGGATATGGACGCATCGGTTCTTTATTTCATTATCAAAATGTCGGCATTGAACCTGATATGCTAACCTGT
GCGAAGGCTATGGGTAACGGTTTTCCTGTAGCTGCATGTTTAGTGAAAGATTATATAGCAGAAGCAATTACTCCAGGAAC
TCATGGATCAACCTATGGTGGCAATCCACTTGCCATGACTGTTGGTAATGCAGTGCTCGATATAATGCTAAAAGAAGGCT
TTTTTGATCATGTTAAAAGAATTAGTAAATATTTAAAAGAAAAGCTGTTGCTTTTAGCTAAAGAATTTCCTGAGATGATT
TTAGAAGTTCGTGGAGAAGGGTTACTAATGGGAATAGAACTAGCAACTCTTGTAGCTGATAAAATTATTAGTCGATCTCT
TGATAAAGGTTTAATAATAACTAGGGTTTTAAACAACAAAGTAGTAAGGGTAACCCCACCACTTATCATTGAGGATGAGC
ATGTGAACGCAGCGTGTAATATGCTTTATGATTTGTTTTTTAAGATTAAAGGTATATAA

Upstream 100 bases:

>100_bases
CCAAATTTTTAGTTGAAGTAGCATAAGAGGTTAAAGGAAAAGCTTTGTGTTAATGGATTCATTTCAGGTATAGTATAGAT
AATACCACAATACTTATAAA

Downstream 100 bases:

>100_bases
AATTCGGCAATATAAATTCAGGCTTGCAAATGCCTCTCATAACATGTAAAATTAATTTTATTTTTTATCACAATAACATC
GTACTTTAATGGATTGGTTA

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MDHVVNAYNRLDTPIVRGEGAYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQSSSLWHCSNIFTIPEQERLAERL
TTLTFADKVFFCSSGLEATEAAIKFIRRYFYSKGQAKRNRIITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPR
NDIKALEEKINNEIAAVFLEPIQSEGGVYPLDVEYLQKVREITKAQGIILCFDEVQCGYGRIGSLFHYQNVGIEPDMLTC
AKAMGNGFPVAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDIMLKEGFFDHVKRISKYLKEKLLLLAKEFPEMI
LEVRGEGLLMGIELATLVADKIISRSLDKGLIITRVLNNKVVRVTPPLIIEDEHVNAACNMLYDLFFKIKGI

Sequences:

>Translated_392_residues
MDHVVNAYNRLDTPIVRGEGAYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQSSSLWHCSNIFTIPEQERLAERL
TTLTFADKVFFCSSGLEATEAAIKFIRRYFYSKGQAKRNRIITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPR
NDIKALEEKINNEIAAVFLEPIQSEGGVYPLDVEYLQKVREITKAQGIILCFDEVQCGYGRIGSLFHYQNVGIEPDMLTC
AKAMGNGFPVAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDIMLKEGFFDHVKRISKYLKEKLLLLAKEFPEMI
LEVRGEGLLMGIELATLVADKIISRSLDKGLIITRVLNNKVVRVTPPLIIEDEHVNAACNMLYDLFFKIKGI
>Mature_392_residues
MDHVVNAYNRLDTPIVRGEGAYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQSSSLWHCSNIFTIPEQERLAERL
TTLTFADKVFFCSSGLEATEAAIKFIRRYFYSKGQAKRNRIITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPR
NDIKALEEKINNEIAAVFLEPIQSEGGVYPLDVEYLQKVREITKAQGIILCFDEVQCGYGRIGSLFHYQNVGIEPDMLTC
AKAMGNGFPVAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDIMLKEGFFDHVKRISKYLKEKLLLLAKEFPEMI
LEVRGEGLLMGIELATLVADKIISRSLDKGLIITRVLNNKVVRVTPPLIIEDEHVNAACNMLYDLFFKIKGI

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=382, Percent_Identity=35.0785340314136, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI13994255, Length=431, Percent_Identity=30.6264501160093, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI284507298, Length=297, Percent_Identity=34.6801346801347, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI37574042, Length=399, Percent_Identity=31.5789473684211, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI226442705, Length=399, Percent_Identity=30.8270676691729, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI226442709, Length=371, Percent_Identity=31.266846361186, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI24119277, Length=385, Percent_Identity=27.012987012987, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI188536080, Length=428, Percent_Identity=23.3644859813084, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679950, Length=428, Percent_Identity=23.3644859813084, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679946, Length=428, Percent_Identity=23.3644859813084, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788044, Length=362, Percent_Identity=41.4364640883978, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1789759, Length=379, Percent_Identity=38.7862796833773, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI145693181, Length=365, Percent_Identity=32.6027397260274, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1789016, Length=405, Percent_Identity=31.1111111111111, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=31.6455696202532, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1786991, Length=412, Percent_Identity=29.126213592233, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1786349, Length=317, Percent_Identity=28.391167192429, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25144271, Length=379, Percent_Identity=36.4116094986807, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI32564660, Length=422, Percent_Identity=31.7535545023697, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=264, Percent_Identity=36.3636363636364, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=414, Percent_Identity=28.2608695652174, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=38.9937106918239, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17541228, Length=423, Percent_Identity=24.113475177305, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=384, Percent_Identity=38.5416666666667, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6323470, Length=391, Percent_Identity=32.9923273657289, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6324386, Length=460, Percent_Identity=23.4782608695652, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321456, Length=410, Percent_Identity=25.1219512195122, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357415, Length=379, Percent_Identity=32.7176781002639, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI28574759, Length=409, Percent_Identity=31.2958435207824, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI161085790, Length=425, Percent_Identity=31.0588235294118, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21356575, Length=404, Percent_Identity=31.1881188118812, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI281366494, Length=424, Percent_Identity=25.7075471698113, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667139, Length=424, Percent_Identity=25.7075471698113, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667143, Length=424, Percent_Identity=25.7075471698113, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43456; Mature: 43456

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHVVNAYNRLDTPIVRGEGAYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQSSS
CCCHHHHHHHCCCCEEECCCCEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
LWHCSNIFTIPEQERLAERLTTLTFADKVFFCSSGLEATEAAIKFIRRYFYSKGQAKRNR
CEEECCEECCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCE
IITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPRNDIKALEEKINNEIAAVFLE
EEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHH
PIQSEGGVYPLDVEYLQKVREITKAQGIILCFDEVQCGYGRIGSLFHYQNVGIEPDMLTC
HHHCCCCEEEECHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEECCCCCCCHHHHH
AKAMGNGFPVAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDIMLKEGFFDHVKR
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
ISKYLKEKLLLLAKEFPEMILEVRGEGLLMGIELATLVADKIISRSLDKGLIITRVLNNK
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
VVRVTPPLIIEDEHVNAACNMLYDLFFKIKGI
EEEECCCEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDHVVNAYNRLDTPIVRGEGAYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQSSS
CCCHHHHHHHCCCCEEECCCCEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
LWHCSNIFTIPEQERLAERLTTLTFADKVFFCSSGLEATEAAIKFIRRYFYSKGQAKRNR
CEEECCEECCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCCCCE
IITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPRNDIKALEEKINNEIAAVFLE
EEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHH
PIQSEGGVYPLDVEYLQKVREITKAQGIILCFDEVQCGYGRIGSLFHYQNVGIEPDMLTC
HHHCCCCEEEECHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEECCCCCCCHHHHH
AKAMGNGFPVAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDIMLKEGFFDHVKR
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
ISKYLKEKLLLLAKEFPEMILEVRGEGLLMGIELATLVADKIISRSLDKGLIITRVLNNK
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
VVRVTPPLIIEDEHVNAACNMLYDLFFKIKGI
EEEECCCEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]