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The map label for this gene is engD [H]

Identifier: 225630121

GI number: 225630121

Start: 321582

End: 322676

Strand: Direct

Name: engD [H]

Synonym: WRi_003030

Alternate gene names: 225630121

Gene position: 321582-322676 (Clockwise)

Preceding gene: 225630118

Following gene: 225630122

Centisome position: 22.24

GC content: 37.99

Gene sequence:

>1095_bases
ATGAGTTTTAACTGCGGTATAGTTGGGTTACCAAACATAGGAAAATCAACCTTATTTAATGCGCTTACAGAGTCAAGTGC
AGCCGAAGCTGCAAATTATCCTTTTTGCACAATCGAGCCAAATATAGGCAAGATTTCGATAAAAGATCAGCGTTTGAAAC
AAATCGCAGCAATTGCCGGTTCAGAGAAGATAATTTATAATCAATTAGAAGTTGTAGATATTGCAGGCCTGGTAAAGGGT
GCGAGCAAAGGTGAAGGGCTCGGCAATAAATTTTTAAGCCATATCAGAGAAGTTGATGCCATCGTTCATCTGCTCAGGTG
CTTTACGGATGACGATATCAGCCATGTACACAGTAAAATAGATCCAATATCAGATGCTGAAGTGGTAGAAATGGAATTAA
TCCTAGCTGATATTGATAGCATAGAAAAAAGGCTTCCTCAATTGGAAAAGAAAGCAAAGCAAGGTGATAAAGAGCTAAAG
AGACAACTTGAATTAATGCAAGAGGTACTGGCTACTTTAAAATTAGGTAAACCTGCAAGAAGTTTGGAGAATATCGATGA
AGATGAGATGAAGTCGCTTCAATTGCTGACAACAAAGCCCGTTATGTACGTTTGCAATGTTGAAGATACAAATGTTATAA
CTGGCAATGAATTATCTAAAAAGGTAGAGAGAATGGCGGAGGAAAATAAAAGTAAATTTTATTGTATTTCAGCAAAACTC
GAAGCAGATATTGCAAATCTTGATAGTGAAGAGGAAAAACAGAGTTTTTTATCGGAATTTGGCTTACAAGAATCAGGCCT
TGATGGAGTAGCGCGTATTATGTATGAAGTGCTGAGTATGATAACTTTCTTTACTGTGGGCCCCAAAGAAGCACGGGCAT
GGCCAGTAAAAATAGGGTCAACAGCCGATAAAGCAGCAGGTGTAATCCACACTGATTTTGAGAAAGGCTTTATAAAAGCA
GAGACAATAAGCTTTGCAGACTACATAAAGTATGGAAGTGAATCAGCTTGCAAAGACGCAGGAAAAATTCGCTTTGAAGG
CAGAGATTATATCATGCAAGATGGTGATATAATGCACTTTAGGTTTAATGTGTAG

Upstream 100 bases:

>100_bases
AGCTATATGTTACTATACCAACAAAATTATTAATAAGCAACTAATTAAGTATAGCAGAAATTTTTAAATTATGCAATAGT
TGTAGCTTTAAATAGCAAAT

Downstream 100 bases:

>100_bases
TAATTTATCCTTTCTATTGGTTTTTTATCTAAGGCATTTTTTACTGTAGATTAATCATTTGATTATAGTATCATTTTAAT
TAAGCTTATGCTTGGGATAT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNIGKISIKDQRLKQIAAIAGSEKIIYNQLEVVDIAGLVKG
ASKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVHSKIDPISDAEVVEMELILADIDSIEKRLPQLEKKAKQGDKELK
RQLELMQEVLATLKLGKPARSLENIDEDEMKSLQLLTTKPVMYVCNVEDTNVITGNELSKKVERMAEENKSKFYCISAKL
EADIANLDSEEEKQSFLSEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPVKIGSTADKAAGVIHTDFEKGFIKA
ETISFADYIKYGSESACKDAGKIRFEGRDYIMQDGDIMHFRFNV

Sequences:

>Translated_364_residues
MSFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNIGKISIKDQRLKQIAAIAGSEKIIYNQLEVVDIAGLVKG
ASKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVHSKIDPISDAEVVEMELILADIDSIEKRLPQLEKKAKQGDKELK
RQLELMQEVLATLKLGKPARSLENIDEDEMKSLQLLTTKPVMYVCNVEDTNVITGNELSKKVERMAEENKSKFYCISAKL
EADIANLDSEEEKQSFLSEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPVKIGSTADKAAGVIHTDFEKGFIKA
ETISFADYIKYGSESACKDAGKIRFEGRDYIMQDGDIMHFRFNV
>Mature_363_residues
SFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNIGKISIKDQRLKQIAAIAGSEKIIYNQLEVVDIAGLVKGA
SKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVHSKIDPISDAEVVEMELILADIDSIEKRLPQLEKKAKQGDKELKR
QLELMQEVLATLKLGKPARSLENIDEDEMKSLQLLTTKPVMYVCNVEDTNVITGNELSKKVERMAEENKSKFYCISAKLE
ADIANLDSEEEKQSFLSEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPVKIGSTADKAAGVIHTDFEKGFIKAE
TISFADYIKYGSESACKDAGKIRFEGRDYIMQDGDIMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=371, Percent_Identity=43.1266846361186, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI58761502, Length=226, Percent_Identity=38.0530973451327, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=50.5464480874317, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1789574, Length=130, Percent_Identity=30, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=41.0326086956522, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17552324, Length=104, Percent_Identity=31.7307692307692, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=37.1657754010695, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6321773, Length=384, Percent_Identity=35.9375, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6321649, Length=157, Percent_Identity=35.031847133758, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=41.4634146341463, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=41.4634146341463, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=41.4634146341463, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=38.8379204892966, Blast_Score=218, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24585318, Length=228, Percent_Identity=28.5087719298246, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40390; Mature: 40258

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNIGKISIKDQRLKQIAAIAG
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHHHHHHHCC
SEKIIYNQLEVVDIAGLVKGASKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVHSKI
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
DPISDAEVVEMELILADIDSIEKRLPQLEKKAKQGDKELKRQLELMQEVLATLKLGKPAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHH
SLENIDEDEMKSLQLLTTKPVMYVCNVEDTNVITGNELSKKVERMAEENKSKFYCISAKL
HHHCCCHHHHHHHHHEECCCEEEEEECCCCCEECCHHHHHHHHHHHHCCCCEEEEEEEEE
EADIANLDSEEEKQSFLSEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPVKIGS
HHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
TADKAAGVIHTDFEKGFIKAETISFADYIKYGSESACKDAGKIRFEGRDYIMQDGDIMHF
CCHHHCCCEEECHHCCCEEHHHHHHHHHHHCCCCHHHCCCCCEEECCCCEEEECCCEEEE
RFNV
EECC
>Mature Secondary Structure 
SFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNIGKISIKDQRLKQIAAIAG
CCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHHHHHHHCC
SEKIIYNQLEVVDIAGLVKGASKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVHSKI
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
DPISDAEVVEMELILADIDSIEKRLPQLEKKAKQGDKELKRQLELMQEVLATLKLGKPAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHH
SLENIDEDEMKSLQLLTTKPVMYVCNVEDTNVITGNELSKKVERMAEENKSKFYCISAKL
HHHCCCHHHHHHHHHEECCCEEEEEECCCCCEECCHHHHHHHHHHHHCCCCEEEEEEEEE
EADIANLDSEEEKQSFLSEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPVKIGS
HHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
TADKAAGVIHTDFEKGFIKAETISFADYIKYGSESACKDAGKIRFEGRDYIMQDGDIMHF
CCHHHCCCEEECHHCCCEEHHHHHHHHHHHCCCCHHHCCCCCEEECCCCEEEECCCEEEE
RFNV
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA