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The map label for this gene is sugE [H]

Identifier: 225629997

GI number: 225629997

Start: 153120

End: 153464

Strand: Reverse

Name: sugE [H]

Synonym: WRi_001510

Alternate gene names: 225629997

Gene position: 153464-153120 (Counterclockwise)

Preceding gene: 225629998

Following gene: 225629996

Centisome position: 10.61

GC content: 34.49

Gene sequence:

>345_bases
ATGAATTGGATATATTTACTCTTATCGTCACTAATTGAAGTGTTCTGGGTCATAACACTTAAGCATAGTTGTGGATTTAC
TCATCTCGTACCATCAATAATTAGCATATTCTCCATGGCTCTTAGTACGTATTTACTTTCGCTCGCTACACGTTCTATAC
CTATCGGAGTATGCTATGCAATTTGGACTGGAGTGGGCGCTATAGGAGCTTCGATACTTGGAGTTTACCTATTTGATGAA
CCAGTTAATTTATTCGAAGTAATATGCTTTATTTTAGTTACATTCGGGATTATAGGATTAAAATTGTTTGATACTGCAAA
ACAAACTGTTGATAAAATGGAATAA

Upstream 100 bases:

>100_bases
TTTCACAGAGAATATTAATTTATCTCAAGTTTTATGTATCGTTTTAATTGTAATAGGAACCATAGGGCTAAAGCTCTCTA
TTTAAACCTAAAGTTTATGC

Downstream 100 bases:

>100_bases
AAGATCCCACTGGGATGAAAGAAGCAGATACTCCATATTGTCATGCAAATTGGAATCCAGACTTTTTTCTATATAGCATG
GTGAAGACGGGAAACCGTAA

Product: sugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MNWIYLLLSSLIEVFWVITLKHSCGFTHLVPSIISIFSMALSTYLLSLATRSIPIGVCYAIWTGVGAIGASILGVYLFDE
PVNLFEVICFILVTFGIIGLKLFDTAKQTVDKME

Sequences:

>Translated_114_residues
MNWIYLLLSSLIEVFWVITLKHSCGFTHLVPSIISIFSMALSTYLLSLATRSIPIGVCYAIWTGVGAIGASILGVYLFDE
PVNLFEVICFILVTFGIIGLKLFDTAKQTVDKME
>Mature_114_residues
MNWIYLLLSSLIEVFWVITLKHSCGFTHLVPSIISIFSMALSTYLLSLATRSIPIGVCYAIWTGVGAIGASILGVYLFDE
PVNLFEVICFILVTFGIIGLKLFDTAKQTVDKME

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=45.0980392156863, Blast_Score=102, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12624; Mature: 12624

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWIYLLLSSLIEVFWVITLKHSCGFTHLVPSIISIFSMALSTYLLSLATRSIPIGVCYA
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IWTGVGAIGASILGVYLFDEPVNLFEVICFILVTFGIIGLKLFDTAKQTVDKME
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNWIYLLLSSLIEVFWVITLKHSCGFTHLVPSIISIFSMALSTYLLSLATRSIPIGVCYA
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IWTGVGAIGASILGVYLFDEPVNLFEVICFILVTFGIIGLKLFDTAKQTVDKME
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]