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The map label for this gene is solA [H]

Identifier: 222527220

GI number: 222527220

Start: 4947549

End: 4948712

Strand: Direct

Name: solA [H]

Synonym: Chy400_4004

Alternate gene names: 222527220

Gene position: 4947549-4948712 (Clockwise)

Preceding gene: 222527218

Following gene: 222527223

Centisome position: 93.9

GC content: 64.52

Gene sequence:

>1164_bases
ATGCACGGTATGAAACCGACCTACGACATCATCATTATCGGCCTCGGCGGAATGGGAAGCGCGGCAGCGTATCACGCCGC
CCGGCGCGGGCAGCGCGTCCTCGGTATCGAGCGCCACACCCTTGCCCACACCCTCGGCTCCAGCCACGGACGTTCCCGCA
TCATTCGCCAGGCATATTTTGAAGACCCGGCCTATGTGCCGTTACTTTTGCGCGCCTACGAGCTATGGCGGCAGATTGAA
CACGATAGCGGTACGCACCTTTTGACCATCACCGGCGGCCTGATGATCGGCCCTCCTGACAGCCACACCGTTGCCGGAGC
GCTCCGCAGTGCCCGGGAACACGGGCTGGAGTACGAACTCCTCGACGCCGCTGCGATCCGGCGCCGTTTCCCGGCGCTAC
ACCCGACCGAGGGCACCATTGCGCTCTACGAACACCAGGCCGGCTTCCTCTGCCCGGAAGCCAGCGTCACCGCGCACCTG
CAATGCGCAGCGGCGCTCGGCGCCGAGATTCACGCTGAAGAAGCGGTGCTGACCTGGGAAGCCGACACCGCTGGCGTGAC
CGTCACAACCTCGCGTGGCCGCTACGTCGCCGAACGCCTGATCATCACACCCGGCCCATGGGCACCGCGTCTCCTGGCCG
ACCTCGGCCTGCCGCTGGTGGTCGAACGCCAAACCCTGCACTGGTTCGCCCCCACGGGTGGCCTGGAGCCATTTCTGCCC
GACCGCTTCCCGATCTATATCTGGGAGACAGAAGACGGCACCCAGTTCTACGGTTTTCCCCACCAGGAAGGGCCACCCGG
CGGCGTCAAGGTGGCCCTCTTCCGCGCCGGTGAACCGTGCGATCCCGATACAGTTGATCGGGTCGTACATCCGGCAGAGA
TCGCAGCCATGCGTGCCGCCATCGCTGATCGCATTCCGGCACTGAACGGCAACCACCTGGCTGCGGTGGTCTGTATGTAC
ACCACCACCCCCGATCAGCACTTCATCGTCGGTTTGCACCCGCAACACCCCAACGTCGTCATCGCCTCGCCGTGTTCTGG
ACATGGCTTCAAATTCGCCAGCGTGATGGGCGAAATCCTGACCGACCTCGCCATCGATGGCACCACCCGCCACCCGATCC
GACTGTTCGATCCACTGCGGTTTCGGGCGCAACAGGCGGGATGA

Upstream 100 bases:

>100_bases
CAGCATACCACACCTGATCCGACATCTCAGGGCTGATCGGCGTGCGTCTGCGGTACGACAAACCGCTCACCCACCATCCC
TGCCCGCAGCGTGTGGTACA

Downstream 100 bases:

>100_bases
GGGTTGGGGTTTCCTTGCCCCCCTCCCTACCTCCCCCCGCTGGCTACGCATTACCCACATGTCGCGCTGCGTCATGCCGG
ACTGCAAGCACTCCCCGTAG

Product: N-methyltryptophan oxidase

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MHGMKPTYDIIIIGLGGMGSAAAYHAARRGQRVLGIERHTLAHTLGSSHGRSRIIRQAYFEDPAYVPLLLRAYELWRQIE
HDSGTHLLTITGGLMIGPPDSHTVAGALRSAREHGLEYELLDAAAIRRRFPALHPTEGTIALYEHQAGFLCPEASVTAHL
QCAAALGAEIHAEEAVLTWEADTAGVTVTTSRGRYVAERLIITPGPWAPRLLADLGLPLVVERQTLHWFAPTGGLEPFLP
DRFPIYIWETEDGTQFYGFPHQEGPPGGVKVALFRAGEPCDPDTVDRVVHPAEIAAMRAAIADRIPALNGNHLAAVVCMY
TTTPDQHFIVGLHPQHPNVVIASPCSGHGFKFASVMGEILTDLAIDGTTRHPIRLFDPLRFRAQQAG

Sequences:

>Translated_387_residues
MHGMKPTYDIIIIGLGGMGSAAAYHAARRGQRVLGIERHTLAHTLGSSHGRSRIIRQAYFEDPAYVPLLLRAYELWRQIE
HDSGTHLLTITGGLMIGPPDSHTVAGALRSAREHGLEYELLDAAAIRRRFPALHPTEGTIALYEHQAGFLCPEASVTAHL
QCAAALGAEIHAEEAVLTWEADTAGVTVTTSRGRYVAERLIITPGPWAPRLLADLGLPLVVERQTLHWFAPTGGLEPFLP
DRFPIYIWETEDGTQFYGFPHQEGPPGGVKVALFRAGEPCDPDTVDRVVHPAEIAAMRAAIADRIPALNGNHLAAVVCMY
TTTPDQHFIVGLHPQHPNVVIASPCSGHGFKFASVMGEILTDLAIDGTTRHPIRLFDPLRFRAQQAG
>Mature_387_residues
MHGMKPTYDIIIIGLGGMGSAAAYHAARRGQRVLGIERHTLAHTLGSSHGRSRIIRQAYFEDPAYVPLLLRAYELWRQIE
HDSGTHLLTITGGLMIGPPDSHTVAGALRSAREHGLEYELLDAAAIRRRFPALHPTEGTIALYEHQAGFLCPEASVTAHL
QCAAALGAEIHAEEAVLTWEADTAGVTVTTSRGRYVAERLIITPGPWAPRLLADLGLPLVVERQTLHWFAPTGGLEPFLP
DRFPIYIWETEDGTQFYGFPHQEGPPGGVKVALFRAGEPCDPDTVDRVVHPAEIAAMRAAIADRIPALNGNHLAAVVCMY
TTTPDQHFIVGLHPQHPNVVIASPCSGHGFKFASVMGEILTDLAIDGTTRHPIRLFDPLRFRAQQAG

Specific function: Catalyzes the oxidative demethylation of sarcosine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI60499001, Length=386, Percent_Identity=32.1243523316062, Blast_Score=195, Evalue=5e-50,
Organism=Escherichia coli, GI1787298, Length=380, Percent_Identity=34.2105263157895, Blast_Score=206, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI115535191, Length=384, Percent_Identity=29.1666666666667, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI25147318, Length=389, Percent_Identity=27.5064267352185, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42145; Mature: 42145

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00895 3_HYDROXYISOBUT_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGMKPTYDIIIIGLGGMGSAAAYHAARRGQRVLGIERHTLAHTLGSSHGRSRIIRQAYF
CCCCCCCEEEEEEEECCCCHHHHHHHHHCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHH
EDPAYVPLLLRAYELWRQIEHDSGTHLLTITGGLMIGPPDSHTVAGALRSAREHGLEYEL
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCHHHHHHHHHHHCCCCEEE
LDAAAIRRRFPALHPTEGTIALYEHQAGFLCPEASVTAHLQCAAALGAEIHAEEAVLTWE
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHEEEHHHHCCEEECCCEEEEEE
ADTAGVTVTTSRGRYVAERLIITPGPWAPRLLADLGLPLVVERQTLHWFAPTGGLEPFLP
CCCCCEEEEECCCCEEEEEEEECCCCCCHHHHHHCCCCEEEEECEEEEECCCCCCCCCCC
DRFPIYIWETEDGTQFYGFPHQEGPPGGVKVALFRAGEPCDPDTVDRVVHPAEIAAMRAA
CCCEEEEEECCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCHHHHHHHHHH
IADRIPALNGNHLAAVVCMYTTTPDQHFIVGLHPQHPNVVIASPCSGHGFKFASVMGEIL
HHHHCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCEEEECCCCCCCEEHHHHHHHHH
TDLAIDGTTRHPIRLFDPLRFRAQQAG
HHHCCCCCCCCCEEECCHHHHHHHCCC
>Mature Secondary Structure
MHGMKPTYDIIIIGLGGMGSAAAYHAARRGQRVLGIERHTLAHTLGSSHGRSRIIRQAYF
CCCCCCCEEEEEEEECCCCHHHHHHHHHCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHH
EDPAYVPLLLRAYELWRQIEHDSGTHLLTITGGLMIGPPDSHTVAGALRSAREHGLEYEL
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCHHHHHHHHHHHCCCCEEE
LDAAAIRRRFPALHPTEGTIALYEHQAGFLCPEASVTAHLQCAAALGAEIHAEEAVLTWE
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHEEEHHHHCCEEECCCEEEEEE
ADTAGVTVTTSRGRYVAERLIITPGPWAPRLLADLGLPLVVERQTLHWFAPTGGLEPFLP
CCCCCEEEEECCCCEEEEEEEECCCCCCHHHHHHCCCCEEEEECEEEEECCCCCCCCCCC
DRFPIYIWETEDGTQFYGFPHQEGPPGGVKVALFRAGEPCDPDTVDRVVHPAEIAAMRAA
CCCEEEEEECCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCHHHHHHHHHH
IADRIPALNGNHLAAVVCMYTTTPDQHFIVGLHPQHPNVVIASPCSGHGFKFASVMGEIL
HHHHCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCEEEECCCCCCCEEHHHHHHHHH
TDLAIDGTTRHPIRLFDPLRFRAQQAG
HHHCCCCCCCCCEEECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368326 [H]