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The map label for this gene is bsaA [H]

Identifier: 222527189

GI number: 222527189

Start: 4922992

End: 4923492

Strand: Direct

Name: bsaA [H]

Synonym: Chy400_3971

Alternate gene names: 222527189

Gene position: 4922992-4923492 (Clockwise)

Preceding gene: 222527187

Following gene: 222527190

Centisome position: 93.43

GC content: 49.3

Gene sequence:

>501_bases
ATGACTATCTATCAGTTCTCCGCACAACGAATTGACGGTTCAACCCAATCACTGGCCGACTTTCGCGGTCAGGTGTTGCT
GATTGTTAATGTAGCCAGCATGTGTGGTTTGGCTCCTCAATATGCGGGTCTCGAACAGCTTTATCGTCGTTATCGCGACC
AGGGCTTCACAGTATTGGGCTTTCCGAGCAACCAGTTTATGCAGGAACCACGCAATAATGAAGCAATTGCCGAATTTTGT
GAGCGTACATATCAGGTGACCTTCCCCCTCTTTGCCAAAATTGATGTCAACGGGCCGAACGAACACCCGTTATTTACCTA
TTTGAAGACTCAATTGCCCGGTCTATTTGGCAGCACAGCGATCAAATGGAACTTCACGAAATTCCTGGTTGATCGCAATG
GCAAGCCATACCGCCGGTACGCACCGACCGATCTGCCATCGCAGATCGAAGACGACATCGTGTTGCTCCTGCGTCAACAG
CCCAAATCTTTGAGTGCATAG

Upstream 100 bases:

>100_bases
GCGTCATTCTCACCCGTAATCCACGCATTTTGGTAGTACAATAATAATGATAATACAAGCACTATCAGAAATATTTAAAT
AAACTTAAAGGAATACACCC

Downstream 100 bases:

>100_bases
TCATCAGTGTCTATACCTGATTGAGCGTGATACCATCGGGTGCACGAGCTACAGGAAGTTGCTCTTCATGACGGGCAAAT
CCTCAACGAATCGCCATAAT

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MTIYQFSAQRIDGSTQSLADFRGQVLLIVNVASMCGLAPQYAGLEQLYRRYRDQGFTVLGFPSNQFMQEPRNNEAIAEFC
ERTYQVTFPLFAKIDVNGPNEHPLFTYLKTQLPGLFGSTAIKWNFTKFLVDRNGKPYRRYAPTDLPSQIEDDIVLLLRQQ
PKSLSA

Sequences:

>Translated_166_residues
MTIYQFSAQRIDGSTQSLADFRGQVLLIVNVASMCGLAPQYAGLEQLYRRYRDQGFTVLGFPSNQFMQEPRNNEAIAEFC
ERTYQVTFPLFAKIDVNGPNEHPLFTYLKTQLPGLFGSTAIKWNFTKFLVDRNGKPYRRYAPTDLPSQIEDDIVLLLRQQ
PKSLSA
>Mature_165_residues
TIYQFSAQRIDGSTQSLADFRGQVLLIVNVASMCGLAPQYAGLEQLYRRYRDQGFTVLGFPSNQFMQEPRNNEAIAEFCE
RTYQVTFPLFAKIDVNGPNEHPLFTYLKTQLPGLFGSTAIKWNFTKFLVDRNGKPYRRYAPTDLPSQIEDDIVLLLRQQP
KSLSA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=45.5128205128205, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=45.5128205128205, Blast_Score=129, Evalue=9e-31,
Organism=Homo sapiens, GI15618997, Length=158, Percent_Identity=43.6708860759494, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI90903238, Length=142, Percent_Identity=43.6619718309859, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=36.25, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI41406084, Length=188, Percent_Identity=37.2340425531915, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI32967607, Length=182, Percent_Identity=37.3626373626374, Blast_Score=97, Evalue=5e-21,
Organism=Homo sapiens, GI4557629, Length=179, Percent_Identity=35.7541899441341, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI33186887, Length=179, Percent_Identity=36.8715083798883, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI6006001, Length=180, Percent_Identity=35.5555555555556, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1788003, Length=174, Percent_Identity=43.6781609195402, Blast_Score=138, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17506887, Length=154, Percent_Identity=46.1038961038961, Blast_Score=133, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=43.0379746835443, Blast_Score=125, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17535473, Length=161, Percent_Identity=41.6149068322981, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI193210707, Length=166, Percent_Identity=42.7710843373494, Blast_Score=115, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI193209493, Length=165, Percent_Identity=35.1515151515151, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17550320, Length=164, Percent_Identity=35.3658536585366, Blast_Score=106, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=40, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322228, Length=140, Percent_Identity=55, Blast_Score=170, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6319721, Length=159, Percent_Identity=48.4276729559748, Blast_Score=166, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322826, Length=161, Percent_Identity=40.9937888198758, Blast_Score=129, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=43.3962264150943, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=43.3962264150943, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=44.0251572327044, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI85726443, Length=160, Percent_Identity=41.25, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 18982; Mature: 18851

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYQFSAQRIDGSTQSLADFRGQVLLIVNVASMCGLAPQYAGLEQLYRRYRDQGFTVLG
CEEEECCHHHCCCCHHHHHHHCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHCCCEEEE
FPSNQFMQEPRNNEAIAEFCERTYQVTFPLFAKIDVNGPNEHPLFTYLKTQLPGLFGSTA
CCCHHHHHCCCCCHHHHHHHHHHEEEEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCE
IKWNFTKFLVDRNGKPYRRYAPTDLPSQIEDDIVLLLRQQPKSLSA
EEEEHEEEEEECCCCCCCCCCCCCCCCHHHHHHEEEECCCCCCCCC
>Mature Secondary Structure 
TIYQFSAQRIDGSTQSLADFRGQVLLIVNVASMCGLAPQYAGLEQLYRRYRDQGFTVLG
EEEECCHHHCCCCHHHHHHHCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHCCCEEEE
FPSNQFMQEPRNNEAIAEFCERTYQVTFPLFAKIDVNGPNEHPLFTYLKTQLPGLFGSTA
CCCHHHHHCCCCCHHHHHHHHHHEEEEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCE
IKWNFTKFLVDRNGKPYRRYAPTDLPSQIEDDIVLLLRQQPKSLSA
EEEEHEEEEEECCCCCCCCCCCCCCCCHHHHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10086841; 11058132 [H]