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The map label for this gene is yciR [C]

Identifier: 222527033

GI number: 222527033

Start: 4745561

End: 4747648

Strand: Reverse

Name: yciR [C]

Synonym: Chy400_3812

Alternate gene names: 222527033

Gene position: 4747648-4745561 (Counterclockwise)

Preceding gene: 222527034

Following gene: 222527031

Centisome position: 90.11

GC content: 52.49

Gene sequence:

>2088_bases
GTGACTCTCCAAATCCTACTCATCGAAGACAATCCAGATCATATCGAGTTGGTGCAACGGGCATTTGAGCAAGGTAATCA
TCAACTTATTGTCGTGGCATCGCTGACAGAAGCACGACAACGCCTGGACGAACGGTATTTTGATCTGATCATTTGTGATT
TGCTCTTGCCCGATGGACGGGGTGATGAGCTGTTGGTTACCGATGCCGATGGCTTAACGTTACCGGTTGTGTTGATGACG
GGTTACGGTGATGAGCGGGCTGCAGTATCTGCCCTGAAAGCGGGTGCACTAGATTATGTTGCCAAAACGCCGGCCACGCT
GCTCGACCTGCCACGTATTGCCGAACGGGCATTACGTGAACGACGACTCATCATCGAGCGGCAGCAGGCTGAACAGGCCC
TACGGCGGAGTGAGCGCCTCTTTCGGGCGATGATTGAACGGAGCAGCGATGCGATTTCGATAGTGGATCGCGATGGCTTT
ATTCGCTATGCCAGTCCCTCAACGCAGACGTTGCTCGGTTATCCGACTGAAGGCTTTCTGACCCAGCCCGTCGAGGGTTT
CGCCTTCATTCATCCAGCCGACCGTGAGCGGGTTCAGCGGCTATTTTTGGATATTATCCAGCAATCTGGCGCCTCGGCAA
TGGTTGAGTTTCGCGCACGCCATGCCAATGGTGGTTGGCGTTGGATTGAAGCAACGGCCTCGAACTGGCTCGATGATCCG
GCAGTGCAGGGGGTGATTGTTAACTATCGTGACATTACCGAGCGCAAGCTGATGGAATTACGGCTTCAGCACGGGGTGTT
GCACGATGCGTTGACTGGCCTGCCTAATCGGGTTCTGTTGAGTGATCGTCTGGCCCAGGCGATCAAACGCAGCCAGCGTA
ACCCACAGTATCACTTTGCTGTGCTCTTTCTTGATCTTGACCACTTTAAGGTGATTAACGACAGCTTCGGGCATCCGGTT
GGTGATCGCTTTCTGGTAACCGCAGCTTCGCGATTACACAGTTGTCTGCGTTCGATAGATACCTGTGCCCGTCTAGGTGG
CGACGAATTTGTTATTTTGCTCGATGATATTCACTCACTTGACGCTGTGGTGCAGGTCGCCAGACGCATTATTCAGCAAT
TGAGTTTGCCGGTTGAAATTGATGGTCAGATGCTTCACTCATCGGTCAGTATTGGGATTGTGTTTGGTTCAGCGGAATAC
AATGATCCGGCGGAAGTATTGCGAGACGCCGATATTGCGATGTATCGGGCAAAAGCGAGTGGTAAATCGCGTTACGAGGT
CTTTCATCCGGCAATGCGTGAAGCAGCTCAGGCGCGTTTAGCACTCGAAAATGAATTACGGCGAGCGGTTGCCCAGCGTG
AGTTTATCGTCTATTATCAACCTATTATGAACATCAGTTCAGGAGGTTTGATCGGGTTTGAGGCGTTGGTGCGCTGGCAA
CATCCAACACGCGGTATCCTGACCCCAGCCGCTTTTCTTGATGTGGCTGAGGAGGTTGGGTTGGGAGATGCTATTGGCTG
GCAGGTGCTTGAACACGTTTGCCAGCAATTGGCCACGTGGCAACACACCTTTTCCCACGCTGCCCATCTGTCGGTGAGTG
TCAATCTCTCGGCGCGCCAGTTCATGCAACCCGATCTCTATGCGCGCATTGTTCAGTTGTTGACGCAATACAACATCCCG
CCGAACTGCCTGAAGCTGGAGCTAACTGAGAGCGCCTTGATGGAGTACAGCCAGGAGGCTGCCGCAGTGCTGGCGCGTTT
GCGGTCATACGGCATTCAGATTGCGATTGATGATTTTGGAGTGGGCTATTCTTCTCTGAGTTATCTGATCCAGTTGCCAA
TTGATCAAATTAAGATTGATCGCAATTTTATCATTCAGCTTGACCAGGCCCATCATTCGCAGGCGATTGTGAGTGCTATC
GTCAATCTGGCCCGGAGTCTTAATCTTGAAGTGGTAGCCGAAGGGCTAGAGACTGCCGAGCAGGTTGACCGTATGCGTAC
AGTCGGTTGTCATTATGGGCAGGGGTATTTGTTAGGGTATCCATTGCCGGCAGCGGAAGCGAGTCGGTTGTTGCAAGGAG
GCGGGTAA

Upstream 100 bases:

>100_bases
AATGCTGAACGATTTGGGTGACTACTGGCTGGAGTGGAATCAGCTCCCCTACAGCCCTCAGTATGTCGCCTGATAACATA
TTCTATACAGGTGGTTGTGC

Downstream 100 bases:

>100_bases
AGGCTTGAACTAACGACATAGCAGATCCGGTAAGGCTGAAGGAGTATTTCGGTAATGAAGAAGCTGGTACAGTAGAACCT
ATTTCAAAAAAACATCTACG

Product: response regulator receiver modulated PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MTLQILLIEDNPDHIELVQRAFEQGNHQLIVVASLTEARQRLDERYFDLIICDLLLPDGRGDELLVTDADGLTLPVVLMT
GYGDERAAVSALKAGALDYVAKTPATLLDLPRIAERALRERRLIIERQQAEQALRRSERLFRAMIERSSDAISIVDRDGF
IRYASPSTQTLLGYPTEGFLTQPVEGFAFIHPADRERVQRLFLDIIQQSGASAMVEFRARHANGGWRWIEATASNWLDDP
AVQGVIVNYRDITERKLMELRLQHGVLHDALTGLPNRVLLSDRLAQAIKRSQRNPQYHFAVLFLDLDHFKVINDSFGHPV
GDRFLVTAASRLHSCLRSIDTCARLGGDEFVILLDDIHSLDAVVQVARRIIQQLSLPVEIDGQMLHSSVSIGIVFGSAEY
NDPAEVLRDADIAMYRAKASGKSRYEVFHPAMREAAQARLALENELRRAVAQREFIVYYQPIMNISSGGLIGFEALVRWQ
HPTRGILTPAAFLDVAEEVGLGDAIGWQVLEHVCQQLATWQHTFSHAAHLSVSVNLSARQFMQPDLYARIVQLLTQYNIP
PNCLKLELTESALMEYSQEAAAVLARLRSYGIQIAIDDFGVGYSSLSYLIQLPIDQIKIDRNFIIQLDQAHHSQAIVSAI
VNLARSLNLEVVAEGLETAEQVDRMRTVGCHYGQGYLLGYPLPAAEASRLLQGGG

Sequences:

>Translated_695_residues
MTLQILLIEDNPDHIELVQRAFEQGNHQLIVVASLTEARQRLDERYFDLIICDLLLPDGRGDELLVTDADGLTLPVVLMT
GYGDERAAVSALKAGALDYVAKTPATLLDLPRIAERALRERRLIIERQQAEQALRRSERLFRAMIERSSDAISIVDRDGF
IRYASPSTQTLLGYPTEGFLTQPVEGFAFIHPADRERVQRLFLDIIQQSGASAMVEFRARHANGGWRWIEATASNWLDDP
AVQGVIVNYRDITERKLMELRLQHGVLHDALTGLPNRVLLSDRLAQAIKRSQRNPQYHFAVLFLDLDHFKVINDSFGHPV
GDRFLVTAASRLHSCLRSIDTCARLGGDEFVILLDDIHSLDAVVQVARRIIQQLSLPVEIDGQMLHSSVSIGIVFGSAEY
NDPAEVLRDADIAMYRAKASGKSRYEVFHPAMREAAQARLALENELRRAVAQREFIVYYQPIMNISSGGLIGFEALVRWQ
HPTRGILTPAAFLDVAEEVGLGDAIGWQVLEHVCQQLATWQHTFSHAAHLSVSVNLSARQFMQPDLYARIVQLLTQYNIP
PNCLKLELTESALMEYSQEAAAVLARLRSYGIQIAIDDFGVGYSSLSYLIQLPIDQIKIDRNFIIQLDQAHHSQAIVSAI
VNLARSLNLEVVAEGLETAEQVDRMRTVGCHYGQGYLLGYPLPAAEASRLLQGGG
>Mature_694_residues
TLQILLIEDNPDHIELVQRAFEQGNHQLIVVASLTEARQRLDERYFDLIICDLLLPDGRGDELLVTDADGLTLPVVLMTG
YGDERAAVSALKAGALDYVAKTPATLLDLPRIAERALRERRLIIERQQAEQALRRSERLFRAMIERSSDAISIVDRDGFI
RYASPSTQTLLGYPTEGFLTQPVEGFAFIHPADRERVQRLFLDIIQQSGASAMVEFRARHANGGWRWIEATASNWLDDPA
VQGVIVNYRDITERKLMELRLQHGVLHDALTGLPNRVLLSDRLAQAIKRSQRNPQYHFAVLFLDLDHFKVINDSFGHPVG
DRFLVTAASRLHSCLRSIDTCARLGGDEFVILLDDIHSLDAVVQVARRIIQQLSLPVEIDGQMLHSSVSIGIVFGSAEYN
DPAEVLRDADIAMYRAKASGKSRYEVFHPAMREAAQARLALENELRRAVAQREFIVYYQPIMNISSGGLIGFEALVRWQH
PTRGILTPAAFLDVAEEVGLGDAIGWQVLEHVCQQLATWQHTFSHAAHLSVSVNLSARQFMQPDLYARIVQLLTQYNIPP
NCLKLELTESALMEYSQEAAAVLARLRSYGIQIAIDDFGVGYSSLSYLIQLPIDQIKIDRNFIIQLDQAHHSQAIVSAIV
NLARSLNLEVVAEGLETAEQVDRMRTVGCHYGQGYLLGYPLPAAEASRLLQGGG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=445, Percent_Identity=37.3033707865169, Blast_Score=288, Evalue=1e-78,
Organism=Escherichia coli, GI87081921, Length=420, Percent_Identity=33.8095238095238, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI226510982, Length=419, Percent_Identity=32.4582338902148, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1790496, Length=247, Percent_Identity=38.8663967611336, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081743, Length=248, Percent_Identity=33.0645161290323, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786507, Length=258, Percent_Identity=35.6589147286822, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081845, Length=249, Percent_Identity=32.9317269076305, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1788502, Length=248, Percent_Identity=32.258064516129, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787055, Length=238, Percent_Identity=30.2521008403361, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081980, Length=264, Percent_Identity=32.9545454545455, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788849, Length=463, Percent_Identity=26.9978401727862, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1788381, Length=567, Percent_Identity=24.3386243386243, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87082096, Length=245, Percent_Identity=35.1020408163265, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87081977, Length=165, Percent_Identity=35.7575757575758, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87081881, Length=299, Percent_Identity=29.4314381270903, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1787262, Length=175, Percent_Identity=32, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786584, Length=183, Percent_Identity=31.1475409836066, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082007, Length=178, Percent_Identity=34.2696629213483, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788956, Length=173, Percent_Identity=35.2601156069364, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787802, Length=146, Percent_Identity=31.5068493150685, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI145693134, Length=181, Percent_Identity=32.5966850828729, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787816, Length=195, Percent_Identity=29.7435897435897, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787410, Length=225, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1788085, Length=178, Percent_Identity=29.2134831460674, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081974, Length=178, Percent_Identity=33.1460674157303, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 77688; Mature: 77557

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQILLIEDNPDHIELVQRAFEQGNHQLIVVASLTEARQRLDERYFDLIICDLLLPDGR
CEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
GDELLVTDADGLTLPVVLMTGYGDERAAVSALKAGALDYVAKTPATLLDLPRIAERALRE
CCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHH
RRLIIERQQAEQALRRSERLFRAMIERSSDAISIVDRDGFIRYASPSTQTLLGYPTEGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCCCCEEEECCCCCCC
TQPVEGFAFIHPADRERVQRLFLDIIQQSGASAMVEFRARHANGGWRWIEATASNWLDDP
CCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECHHCCCCCC
AVQGVIVNYRDITERKLMELRLQHGVLHDALTGLPNRVLLSDRLAQAIKRSQRNPQYHFA
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEE
VLFLDLDHFKVINDSFGHPVGDRFLVTAASRLHSCLRSIDTCARLGGDEFVILLDDIHSL
EEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHH
DAVVQVARRIIQQLSLPVEIDGQMLHSSVSIGIVFGSAEYNDPAEVLRDADIAMYRAKAS
HHHHHHHHHHHHHCCCCEEECCHHHHCCEEEEEEECCCCCCCHHHHHHCCHHHEEEECCC
GKSRYEVFHPAMREAAQARLALENELRRAVAQREFIVYYQPIMNISSGGLIGFEALVRWQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCCHHHHHHHCC
HPTRGILTPAAFLDVAEEVGLGDAIGWQVLEHVCQQLATWQHTFSHAAHLSVSVNLSARQ
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCHHH
FMQPDLYARIVQLLTQYNIPPNCLKLELTESALMEYSQEAAAVLARLRSYGIQIAIDDFG
HCCHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
VGYSSLSYLIQLPIDQIKIDRNFIIQLDQAHHSQAIVSAIVNLARSLNLEVVAEGLETAE
CCHHHHHHHHHCCHHHEEECCEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QVDRMRTVGCHYGQGYLLGYPLPAAEASRLLQGGG
HHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCC
>Mature Secondary Structure 
TLQILLIEDNPDHIELVQRAFEQGNHQLIVVASLTEARQRLDERYFDLIICDLLLPDGR
EEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
GDELLVTDADGLTLPVVLMTGYGDERAAVSALKAGALDYVAKTPATLLDLPRIAERALRE
CCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHH
RRLIIERQQAEQALRRSERLFRAMIERSSDAISIVDRDGFIRYASPSTQTLLGYPTEGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCCCCEEEECCCCCCC
TQPVEGFAFIHPADRERVQRLFLDIIQQSGASAMVEFRARHANGGWRWIEATASNWLDDP
CCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECHHCCCCCC
AVQGVIVNYRDITERKLMELRLQHGVLHDALTGLPNRVLLSDRLAQAIKRSQRNPQYHFA
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEE
VLFLDLDHFKVINDSFGHPVGDRFLVTAASRLHSCLRSIDTCARLGGDEFVILLDDIHSL
EEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHH
DAVVQVARRIIQQLSLPVEIDGQMLHSSVSIGIVFGSAEYNDPAEVLRDADIAMYRAKAS
HHHHHHHHHHHHHCCCCEEECCHHHHCCEEEEEEECCCCCCCHHHHHHCCHHHEEEECCC
GKSRYEVFHPAMREAAQARLALENELRRAVAQREFIVYYQPIMNISSGGLIGFEALVRWQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCCHHHHHHHCC
HPTRGILTPAAFLDVAEEVGLGDAIGWQVLEHVCQQLATWQHTFSHAAHLSVSVNLSARQ
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCHHH
FMQPDLYARIVQLLTQYNIPPNCLKLELTESALMEYSQEAAAVLARLRSYGIQIAIDDFG
HCCHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
VGYSSLSYLIQLPIDQIKIDRNFIIQLDQAHHSQAIVSAIVNLARSLNLEVVAEGLETAE
CCHHHHHHHHHCCHHHEEECCEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QVDRMRTVGCHYGQGYLLGYPLPAAEASRLLQGGG
HHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]