Click here to switch to the map view.

The map label for this gene is yicI [C]

Identifier: 222526933

GI number: 222526933

Start: 4629279

End: 4631189

Strand: Reverse

Name: yicI [C]

Synonym: Chy400_3711

Alternate gene names: 222526933

Gene position: 4631189-4629279 (Counterclockwise)

Preceding gene: 222526936

Following gene: 222526932

Centisome position: 87.9

GC content: 60.28

Gene sequence:

>1911_bases
ATGCAACATGTCATTCACAGCCCAGCCGGTACCGCCACGTTCGATGGTCACGGTCAGATCGTTTTTACTCACGAAGGCCG
CACGGTCTTGTGCTGTCGAGGGGCGACGGCGTATGCCTACGGTACGGATATACCGACTACCGGCGTTGTAAGTGCTGATG
TTACCGACCATCAGGCTCGTCTTCACTACGCGACCACGCGCCCAGAGGTGATACTGCGCCTGACAATTGAGACGACTCCC
ATCGGCTTTCGCTTGAGCTGGTCTGGCCCGCCCCATCTGCCGGCACTGCGGGTTGAATGGCAGCTTGAACCAGGACGCCC
CTGGTACGGTATGGGTGAGCGCGTGTTTCAGCATTGGCCGCTCGACCGTGGTGTGGTGATCTCCGATCCGTTCGAGCCAA
TTGACCATGGTCGTGACGGTACGCTGAATATCGCGACTCCCTTTTGGGTAAATGCTGCCGGGGCTGCGATTTGGCTGGAA
GAGGGTGATGGAGAGCTGGCAGTGACGATGAACCGCGACGGTGATGGGTTGTTACGTATCACTGCGCGCGAGGCACCACC
GCCGCCTACGCTCGGCTTCGATGAACGCTATGCCGCGCCTGGCCCGGCCCTGGTTGCCCAGGTGATCCTGGCAGCCAATG
CGCCGGCTGCGTTTTACACGGCACTGCCACTGTTGGGCCGACCGTCCGCTGCGCCACCGCTGGAGTTGTTTAGCCGCCCG
ATCTGGACGACCTGGGCACATTATAAGATGCCGGTCACGCAACGGGATGTGTCCGATTTTGCAGCTCAGATCGTTGCCCG
TGGTTATCCCTACTCGGTGCTGGAGATTGATGATCGCTGGCAACGGGGCTATGGGGCGTATGTGTTCGATCCGCGGAAGT
TCCCCGATCCGCGGGCGATGGTGGATGAGCTGCACGCAGCCGGTTTTAAGGTGACGCTCTGGACACCAACGTTTTTCGAT
CCGGCTGACCCAGCCTTTGCGGTCGCGGCACGGCGCGGCTATTTGATCCGTCATCCCGCCGATAATGCACCTTATCTGGT
GCGGTGGTGGCAGGGCTACGGCGGTGTGCTCGATATGACCAATCCTGAAGCGGTGGCGTGGTGGCTCAGTGAACTACGTG
CTCTTCAGGCAGAGACCGGGGTCGATGGGTTTAAGTTTGATGCCGGTGAAGCCAATTTTATCCCGCCCGATGCCATCTGT
TACGCGCGCGAGCCGCGCCGTCGCTATGCCGACCGCTACACCGAATTTGTGGCCGATCACTTTGCCTATACCGAGGTGCG
CGTCGGTTGGCGCGGTCAGCGGCGTGGCATTCTCTACCGCGAGTGGGATAAGTGGAGTCGCTGGGGGATTGATAATGGTC
TGCACAGTGTGCTAACACAGGCGCTGACGCTCAGTCTGTGTGGTTATCCGTTTGTGCTGCCGGATATGATCGGCGGGAAT
GCGTATCAGGATGAGGTGCCGGATGGCGAGCTGATGGTGCGCTGGACGCAACTCTGTGCGTTGTTGCCAACGATGCAATT
CAGCGTTCATCCGTGGCAGTACGGCGCCGAGGTTGACGCTATTTGCCGCCAGTATGCGCAGCTCCACGTTGATCTGACGC
CGTATCTGGCAACGCTGATCGAAGAGAATCTGCGCGACGGCACACCACTTGTGCGCCCCCTCTTCTGGTACGCGCCAACG
GATACGCAGGCATTGCATTGCGATGATCAGTTCCTGCTCGGTGCTCGCTATCTGGTGGCACCGGTTGTCCGCCCTGGTCA
GCGCCGGCGCGATGTCTACCTGCCGGCAGGCGTCTGGCGTGACTACTGGAGTGGTGCGATTCATCAAGGGCCAGTCGCTC
TCACCGATGTACCGGCGCCGCTTGAGCAGATGCCGCTCTTCGAGCGACAGGATGAACGGTCGGGCCAATGA

Upstream 100 bases:

>100_bases
TCTGTGGTGCAACCACCCCAGCGCTCTTCGGAGTTTGCCCCATACTTGCCGCTATCTGGTATCATCAGTGCGTGTACTGA
AGTGATATGGAGATACGGTC

Downstream 100 bases:

>100_bases
ACCGGTCAATCCCATAAAACAACAGAGCTGTGAGGTGTATATGCAGCACTCCGTTCGCGTTCATCGTAACGGCATCGAGC
TTGATGGAAAACCCTTTTAT

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MQHVIHSPAGTATFDGHGQIVFTHEGRTVLCCRGATAYAYGTDIPTTGVVSADVTDHQARLHYATTRPEVILRLTIETTP
IGFRLSWSGPPHLPALRVEWQLEPGRPWYGMGERVFQHWPLDRGVVISDPFEPIDHGRDGTLNIATPFWVNAAGAAIWLE
EGDGELAVTMNRDGDGLLRITAREAPPPPTLGFDERYAAPGPALVAQVILAANAPAAFYTALPLLGRPSAAPPLELFSRP
IWTTWAHYKMPVTQRDVSDFAAQIVARGYPYSVLEIDDRWQRGYGAYVFDPRKFPDPRAMVDELHAAGFKVTLWTPTFFD
PADPAFAVAARRGYLIRHPADNAPYLVRWWQGYGGVLDMTNPEAVAWWLSELRALQAETGVDGFKFDAGEANFIPPDAIC
YAREPRRRYADRYTEFVADHFAYTEVRVGWRGQRRGILYREWDKWSRWGIDNGLHSVLTQALTLSLCGYPFVLPDMIGGN
AYQDEVPDGELMVRWTQLCALLPTMQFSVHPWQYGAEVDAICRQYAQLHVDLTPYLATLIEENLRDGTPLVRPLFWYAPT
DTQALHCDDQFLLGARYLVAPVVRPGQRRRDVYLPAGVWRDYWSGAIHQGPVALTDVPAPLEQMPLFERQDERSGQ

Sequences:

>Translated_636_residues
MQHVIHSPAGTATFDGHGQIVFTHEGRTVLCCRGATAYAYGTDIPTTGVVSADVTDHQARLHYATTRPEVILRLTIETTP
IGFRLSWSGPPHLPALRVEWQLEPGRPWYGMGERVFQHWPLDRGVVISDPFEPIDHGRDGTLNIATPFWVNAAGAAIWLE
EGDGELAVTMNRDGDGLLRITAREAPPPPTLGFDERYAAPGPALVAQVILAANAPAAFYTALPLLGRPSAAPPLELFSRP
IWTTWAHYKMPVTQRDVSDFAAQIVARGYPYSVLEIDDRWQRGYGAYVFDPRKFPDPRAMVDELHAAGFKVTLWTPTFFD
PADPAFAVAARRGYLIRHPADNAPYLVRWWQGYGGVLDMTNPEAVAWWLSELRALQAETGVDGFKFDAGEANFIPPDAIC
YAREPRRRYADRYTEFVADHFAYTEVRVGWRGQRRGILYREWDKWSRWGIDNGLHSVLTQALTLSLCGYPFVLPDMIGGN
AYQDEVPDGELMVRWTQLCALLPTMQFSVHPWQYGAEVDAICRQYAQLHVDLTPYLATLIEENLRDGTPLVRPLFWYAPT
DTQALHCDDQFLLGARYLVAPVVRPGQRRRDVYLPAGVWRDYWSGAIHQGPVALTDVPAPLEQMPLFERQDERSGQ
>Mature_636_residues
MQHVIHSPAGTATFDGHGQIVFTHEGRTVLCCRGATAYAYGTDIPTTGVVSADVTDHQARLHYATTRPEVILRLTIETTP
IGFRLSWSGPPHLPALRVEWQLEPGRPWYGMGERVFQHWPLDRGVVISDPFEPIDHGRDGTLNIATPFWVNAAGAAIWLE
EGDGELAVTMNRDGDGLLRITAREAPPPPTLGFDERYAAPGPALVAQVILAANAPAAFYTALPLLGRPSAAPPLELFSRP
IWTTWAHYKMPVTQRDVSDFAAQIVARGYPYSVLEIDDRWQRGYGAYVFDPRKFPDPRAMVDELHAAGFKVTLWTPTFFD
PADPAFAVAARRGYLIRHPADNAPYLVRWWQGYGGVLDMTNPEAVAWWLSELRALQAETGVDGFKFDAGEANFIPPDAIC
YAREPRRRYADRYTEFVADHFAYTEVRVGWRGQRRGILYREWDKWSRWGIDNGLHSVLTQALTLSLCGYPFVLPDMIGGN
AYQDEVPDGELMVRWTQLCALLPTMQFSVHPWQYGAEVDAICRQYAQLHVDLTPYLATLIEENLRDGTPLVRPLFWYAPT
DTQALHCDDQFLLGARYLVAPVVRPGQRRRDVYLPAGVWRDYWSGAIHQGPVALTDVPAPLEQMPLFERQDERSGQ

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI153791946, Length=582, Percent_Identity=38.1443298969072, Blast_Score=338, Evalue=7e-93,
Organism=Homo sapiens, GI88900491, Length=608, Percent_Identity=25.4934210526316, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI38202257, Length=608, Percent_Identity=25.4934210526316, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI66346737, Length=460, Percent_Identity=24.5652173913043, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI119393895, Length=411, Percent_Identity=25.5474452554745, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI119393893, Length=411, Percent_Identity=25.5474452554745, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI119393891, Length=411, Percent_Identity=25.5474452554745, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI310115361, Length=186, Percent_Identity=31.1827956989247, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI221316699, Length=210, Percent_Identity=29.5238095238095, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI2367256, Length=406, Percent_Identity=27.3399014778325, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI2367323, Length=365, Percent_Identity=26.5753424657534, Blast_Score=122, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17560798, Length=419, Percent_Identity=25.5369928400955, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560800, Length=419, Percent_Identity=25.5369928400955, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71991189, Length=409, Percent_Identity=25.4278728606357, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985706, Length=272, Percent_Identity=24.6323529411765, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319706, Length=178, Percent_Identity=28.6516853932584, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24650054, Length=537, Percent_Identity=34.8230912476723, Blast_Score=309, Evalue=3e-84,
Organism=Drosophila melanogaster, GI28571440, Length=650, Percent_Identity=25.5384615384615, Blast_Score=172, Evalue=8e-43,
Organism=Drosophila melanogaster, GI28571438, Length=650, Percent_Identity=25.5384615384615, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24643749, Length=496, Percent_Identity=22.5806451612903, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24643753, Length=496, Percent_Identity=22.5806451612903, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24643751, Length=496, Percent_Identity=22.5806451612903, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24643746, Length=496, Percent_Identity=22.5806451612903, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357605, Length=496, Percent_Identity=22.5806451612903, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 71521; Mature: 71521

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHVIHSPAGTATFDGHGQIVFTHEGRTVLCCRGATAYAYGTDIPTTGVVSADVTDHQAR
CCCEECCCCCCCEECCCCEEEEEECCCEEEEECCCEEEEECCCCCCCCEEECCCCCCCEE
LHYATTRPEVILRLTIETTPIGFRLSWSGPPHLPALRVEWQLEPGRPWYGMGERVFQHWP
EEEECCCCEEEEEEEEEECCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHCC
LDRGVVISDPFEPIDHGRDGTLNIATPFWVNAAGAAIWLEEGDGELAVTMNRDGDGLLRI
CCCCEEECCCCCHHHCCCCCEEEECCCCEEECCCEEEEEEECCCEEEEEEECCCCCEEEE
TAREAPPPPTLGFDERYAAPGPALVAQVILAANAPAAFYTALPLLGRPSAAPPLELFSRP
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHCCC
IWTTWAHYKMPVTQRDVSDFAAQIVARGYPYSVLEIDDRWQRGYGAYVFDPRKFPDPRAM
CEECEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCEEEECCCCCCCHHHH
VDELHAAGFKVTLWTPTFFDPADPAFAVAARRGYLIRHPADNAPYLVRWWQGYGGVLDMT
HHHHHHCCEEEEEECCCCCCCCCCHHHHHHHCCEEEECCCCCCCEEEEEECCCCCEEECC
NPEAVAWWLSELRALQAETGVDGFKFDAGEANFIPPDAICYAREPRRRYADRYTEFVADH
CCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHH
FAYTEVRVGWRGQRRGILYREWDKWSRWGIDNGLHSVLTQALTLSLCGYPFVLPDMIGGN
HEEEEEEECCCCCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHCCCCEECHHHCCCC
AYQDEVPDGELMVRWTQLCALLPTMQFSVHPWQYGAEVDAICRQYAQLHVDLTPYLATLI
CCCCCCCCCHHHHHHHHHHHHHHHHHEEECCHHCCCCHHHHHHHHHHEEECHHHHHHHHH
EENLRDGTPLVRPLFWYAPTDTQALHCDDQFLLGARYLVAPVVRPGQRRRDVYLPAGVWR
HHHHCCCCCCCCEEEEECCCCCCEEECCCHHHHCCHHHHHHCCCCCCCCCEEEECCHHHH
DYWSGAIHQGPVALTDVPAPLEQMPLFERQDERSGQ
HHHCCCCCCCCEEEECCCCCHHHCCCCCCCHHCCCC
>Mature Secondary Structure
MQHVIHSPAGTATFDGHGQIVFTHEGRTVLCCRGATAYAYGTDIPTTGVVSADVTDHQAR
CCCEECCCCCCCEECCCCEEEEEECCCEEEEECCCEEEEECCCCCCCCEEECCCCCCCEE
LHYATTRPEVILRLTIETTPIGFRLSWSGPPHLPALRVEWQLEPGRPWYGMGERVFQHWP
EEEECCCCEEEEEEEEEECCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHCC
LDRGVVISDPFEPIDHGRDGTLNIATPFWVNAAGAAIWLEEGDGELAVTMNRDGDGLLRI
CCCCEEECCCCCHHHCCCCCEEEECCCCEEECCCEEEEEEECCCEEEEEEECCCCCEEEE
TAREAPPPPTLGFDERYAAPGPALVAQVILAANAPAAFYTALPLLGRPSAAPPLELFSRP
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHCCC
IWTTWAHYKMPVTQRDVSDFAAQIVARGYPYSVLEIDDRWQRGYGAYVFDPRKFPDPRAM
CEECEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCEEEECCCCCCCHHHH
VDELHAAGFKVTLWTPTFFDPADPAFAVAARRGYLIRHPADNAPYLVRWWQGYGGVLDMT
HHHHHHCCEEEEEECCCCCCCCCCHHHHHHHCCEEEECCCCCCCEEEEEECCCCCEEECC
NPEAVAWWLSELRALQAETGVDGFKFDAGEANFIPPDAICYAREPRRRYADRYTEFVADH
CCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHH
FAYTEVRVGWRGQRRGILYREWDKWSRWGIDNGLHSVLTQALTLSLCGYPFVLPDMIGGN
HEEEEEEECCCCCCCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHCCCCEECHHHCCCC
AYQDEVPDGELMVRWTQLCALLPTMQFSVHPWQYGAEVDAICRQYAQLHVDLTPYLATLI
CCCCCCCCCHHHHHHHHHHHHHHHHHEEECCHHCCCCHHHHHHHHHHEEECHHHHHHHHH
EENLRDGTPLVRPLFWYAPTDTQALHCDDQFLLGARYLVAPVVRPGQRRRDVYLPAGVWR
HHHHCCCCCCCCEEEEECCCCCCEEECCCHHHHCCHHHHHHCCCCCCCCCEEEECCHHHH
DYWSGAIHQGPVALTDVPAPLEQMPLFERQDERSGQ
HHHCCCCCCCCEEEECCCCCHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]