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The map label for this gene is yycG [H]

Identifier: 222526515

GI number: 222526515

Start: 4090320

End: 4092500

Strand: Reverse

Name: yycG [H]

Synonym: Chy400_3282

Alternate gene names: 222526515

Gene position: 4092500-4090320 (Counterclockwise)

Preceding gene: 222526518

Following gene: 222526508

Centisome position: 77.67

GC content: 56.17

Gene sequence:

>2181_bases
ATGACACACGAACCAGAAGACATCACAACCGGCTACTTGAGTGTACTGAGTGCGGCTTCCCGTTTATTGCAGGAGGAATT
GCCGCTGGTACAACGTATCCATCGGCTCTTCGGGCTTTTGCGTCTCGCAATCCGCTACCGGGATGCACGCCTGACCTGCT
GGTTACAATCCGCACGACCCGGTGCGCATCGCCAGCAGATTTTTTCGCCGGAGTCGTGGGCTTATCCGTGGGACGATACC
CTGACTCGTTCGGTAGCACTTGGCGGGAAGACGGTTATCAAGACGATTGCGCTCGGTAGTGCCGGTCAGCCAGATAAAAA
CTTGCCCGTGATCCCTGCCGGTTATCTGGGAGCACCGATCTTTTGGGGCGGCAGATTGTGGGGGGTTCTCGAACTACGCA
ACGACGATCTACGACGATTTACCGGCAGAATCAGCGAGCTTATCGAGGCACTGAAGCCGCTGCTGGCGGCTGCTATTGCC
CAAGAGGGTGCCCGGCTCCCCCAGTTACCGACACCACGCTTTGCCGGTGAAACACCGATTGGCCTGACGCTCACCCCTTC
ACTACGCCAAAAGATGATCGCTCTTAATGAACAGCTCGACCGTACTATTGACCTGCACGAGCTGACCGGAGTCATCTTGC
GTCGGGCATTAGAGGGGAGCGGTGCTGAAGCAGGAGCAGTTGCACTGGTCGATTATGACAAACGTGAACTGGTGCTGCAC
CTGTACGAAGGGTACGAAGCCGAGCGTTCCAGACGCGCACTGCCCGCTCTACCGCGGCAGCGTTGGAGTTGGGAGATAGG
CCTGGCCGGTCAGGCAGTTCAGATGCGACGACCTTTGCTGGTTCGTGATGCAGGACGCGAGCCGGGATTGCCGAACGCGA
TGCCATTTCTGGCCGAGCTGGCAGCCCCGATTATCGTCGATGATCGGGTATTGGCAGTGCTCATCCTGCATAGTCGTCGG
TCGACAACCTTTACCGAAGAGGTGCTGGCGTTCATTACCACCCTCTGCGAGCGCGCTGCCCACCCGCTGGCCCGTGCGAT
GTCTTATCAGGCCGCTTACGAAACATCGTACCATCTCGGTCAGGTCTTCAGCAGTCTACCGATAGGGCTGGCGCTCCTCG
ATTTGAATGGACGAGTTATTCGGGCCAATCCGGCCTGGAATCAGGTCTGGCGCTTAGATGCGCAGCCACAACGGCCGTCG
TTCTACGTCGGGATTGATCTGGTTGAGCATTTGCTGGCGCGGCTCAACGATCCATTCCGGCTCAGCGAATTTTGTGATCT
CGGTCAGCGCACCCCTGATCAGACGTTTGAAACGAGCCTCCAGCTCCGCAACCCATACCAGGAATTACACGTGCTCTCAG
TACCAACCCGCGATAGTCAGCAACAGCTTACCGGACGATTGTGGGTGGTCAGTGATCGTACACGCGAGCGCGAGTCTGAC
CGGCTCAAAGATGAGTTTATCGGCATTGTGTCGCACGAACTGCGCACACCACTGACCTCAATTCTCGGTTATACCGAGAT
TCTGCTGAACCGGCAAGACCTCGACTACGAGAGCCAGCGCGAGTTTTTGCAGACGGTCTCTAATGAGGCAGAGCGATTGT
TTAAGATGGTCAAAGATTTGCTGGATGTGTCACGGCTGGAGGCCGGTGTCGTAAAGCTGAACCGCTGGGCAGTTGGTCTG
TGGCAGGTGATTGAAGAGCTGACCCTCCAGTTGCATACTCAATTGATCCATCACAAACTCTTGATCGATGCCCGAACGCC
GTTACCACCGGTCTTTGCCGACCGTGACAAGGTCAAACAGATTATCTTCAATCTGCTGAGCAACGCCATCAAGTATAGCC
CGGAAGGAAGTGAAATTCAGCTCACCGTGCGCAGAGCCAACGCAGACGACTTGCCGGCGACGCATCCGCCCGGTCAGTGG
ATGTTAATTGTGGTGCGCGATGAAGGAATCGGTATCAAACCTGAAGATCAGGCCCGGTTGTTTGAGCGGTTTCAGCGCGT
TGATAACAGCAATACCCGCCAGAAGAGTGGGGTTGGTTTGGGATTGTATATCTCTCGTTTGCTGGTCGAACTCCACGGTG
GTCGAATCTGGGTGAAGAGTGTTGAGGGGAGTGGCAGCAGCTTCTCGTTCACGCTGCCAATCTGGACAGCACCAGCCAAT
GAACAGGGTCAGGAACCATGA

Upstream 100 bases:

>100_bases
CCTTGTGTTCCACCGTAATACCGATGGATGTAGCATATCATAGCACAGAGTTATTACGAGATAATTGACAGCTACTCACG
GTTAGCTACAATACACGACA

Downstream 100 bases:

>100_bases
GGGAGGGGCACCACGTGGGCTGCCCCTCCCGGGTTGGCTCAAGCGTGAATGGCAGAACGTCGATATTTAGAACCTGTTTC
AAAAACATTTACGAGAAGTT

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MTHEPEDITTGYLSVLSAASRLLQEELPLVQRIHRLFGLLRLAIRYRDARLTCWLQSARPGAHRQQIFSPESWAYPWDDT
LTRSVALGGKTVIKTIALGSAGQPDKNLPVIPAGYLGAPIFWGGRLWGVLELRNDDLRRFTGRISELIEALKPLLAAAIA
QEGARLPQLPTPRFAGETPIGLTLTPSLRQKMIALNEQLDRTIDLHELTGVILRRALEGSGAEAGAVALVDYDKRELVLH
LYEGYEAERSRRALPALPRQRWSWEIGLAGQAVQMRRPLLVRDAGREPGLPNAMPFLAELAAPIIVDDRVLAVLILHSRR
STTFTEEVLAFITTLCERAAHPLARAMSYQAAYETSYHLGQVFSSLPIGLALLDLNGRVIRANPAWNQVWRLDAQPQRPS
FYVGIDLVEHLLARLNDPFRLSEFCDLGQRTPDQTFETSLQLRNPYQELHVLSVPTRDSQQQLTGRLWVVSDRTRERESD
RLKDEFIGIVSHELRTPLTSILGYTEILLNRQDLDYESQREFLQTVSNEAERLFKMVKDLLDVSRLEAGVVKLNRWAVGL
WQVIEELTLQLHTQLIHHKLLIDARTPLPPVFADRDKVKQIIFNLLSNAIKYSPEGSEIQLTVRRANADDLPATHPPGQW
MLIVVRDEGIGIKPEDQARLFERFQRVDNSNTRQKSGVGLGLYISRLLVELHGGRIWVKSVEGSGSSFSFTLPIWTAPAN
EQGQEP

Sequences:

>Translated_726_residues
MTHEPEDITTGYLSVLSAASRLLQEELPLVQRIHRLFGLLRLAIRYRDARLTCWLQSARPGAHRQQIFSPESWAYPWDDT
LTRSVALGGKTVIKTIALGSAGQPDKNLPVIPAGYLGAPIFWGGRLWGVLELRNDDLRRFTGRISELIEALKPLLAAAIA
QEGARLPQLPTPRFAGETPIGLTLTPSLRQKMIALNEQLDRTIDLHELTGVILRRALEGSGAEAGAVALVDYDKRELVLH
LYEGYEAERSRRALPALPRQRWSWEIGLAGQAVQMRRPLLVRDAGREPGLPNAMPFLAELAAPIIVDDRVLAVLILHSRR
STTFTEEVLAFITTLCERAAHPLARAMSYQAAYETSYHLGQVFSSLPIGLALLDLNGRVIRANPAWNQVWRLDAQPQRPS
FYVGIDLVEHLLARLNDPFRLSEFCDLGQRTPDQTFETSLQLRNPYQELHVLSVPTRDSQQQLTGRLWVVSDRTRERESD
RLKDEFIGIVSHELRTPLTSILGYTEILLNRQDLDYESQREFLQTVSNEAERLFKMVKDLLDVSRLEAGVVKLNRWAVGL
WQVIEELTLQLHTQLIHHKLLIDARTPLPPVFADRDKVKQIIFNLLSNAIKYSPEGSEIQLTVRRANADDLPATHPPGQW
MLIVVRDEGIGIKPEDQARLFERFQRVDNSNTRQKSGVGLGLYISRLLVELHGGRIWVKSVEGSGSSFSFTLPIWTAPAN
EQGQEP
>Mature_725_residues
THEPEDITTGYLSVLSAASRLLQEELPLVQRIHRLFGLLRLAIRYRDARLTCWLQSARPGAHRQQIFSPESWAYPWDDTL
TRSVALGGKTVIKTIALGSAGQPDKNLPVIPAGYLGAPIFWGGRLWGVLELRNDDLRRFTGRISELIEALKPLLAAAIAQ
EGARLPQLPTPRFAGETPIGLTLTPSLRQKMIALNEQLDRTIDLHELTGVILRRALEGSGAEAGAVALVDYDKRELVLHL
YEGYEAERSRRALPALPRQRWSWEIGLAGQAVQMRRPLLVRDAGREPGLPNAMPFLAELAAPIIVDDRVLAVLILHSRRS
TTFTEEVLAFITTLCERAAHPLARAMSYQAAYETSYHLGQVFSSLPIGLALLDLNGRVIRANPAWNQVWRLDAQPQRPSF
YVGIDLVEHLLARLNDPFRLSEFCDLGQRTPDQTFETSLQLRNPYQELHVLSVPTRDSQQQLTGRLWVVSDRTRERESDR
LKDEFIGIVSHELRTPLTSILGYTEILLNRQDLDYESQREFLQTVSNEAERLFKMVKDLLDVSRLEAGVVKLNRWAVGLW
QVIEELTLQLHTQLIHHKLLIDARTPLPPVFADRDKVKQIIFNLLSNAIKYSPEGSEIQLTVRRANADDLPATHPPGQWM
LIVVRDEGIGIKPEDQARLFERFQRVDNSNTRQKSGVGLGLYISRLLVELHGGRIWVKSVEGSGSSFSFTLPIWTAPANE
QGQEP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=251, Percent_Identity=35.0597609561753, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI1786600, Length=250, Percent_Identity=34, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=33.6099585062241, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=33.7448559670782, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=27.6422764227642, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788549, Length=393, Percent_Identity=27.2264631043257, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081816, Length=252, Percent_Identity=30.5555555555556, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1786912, Length=259, Percent_Identity=29.7297297297297, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=27.7310924369748, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=31.2236286919831, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=30.2521008403361, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=30.1369863013699, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788279, Length=230, Percent_Identity=28.695652173913, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787894, Length=244, Percent_Identity=26.2295081967213, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790300, Length=368, Percent_Identity=27.7173913043478, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1789403, Length=285, Percent_Identity=28.0701754385965, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790861, Length=240, Percent_Identity=27.0833333333333, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=252, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81883; Mature: 81752

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHEPEDITTGYLSVLSAASRLLQEELPLVQRIHRLFGLLRLAIRYRDARLTCWLQSARP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
GAHRQQIFSPESWAYPWDDTLTRSVALGGKTVIKTIALGSAGQPDKNLPVIPAGYLGAPI
CCHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEECCHHCCCCE
FWGGRLWGVLELRNDDLRRFTGRISELIEALKPLLAAAIAQEGARLPQLPTPRFAGETPI
EECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GLTLTPSLRQKMIALNEQLDRTIDLHELTGVILRRALEGSGAEAGAVALVDYDKRELVLH
CEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHH
LYEGYEAERSRRALPALPRQRWSWEIGLAGQAVQMRRPLLVRDAGREPGLPNAMPFLAEL
HHHCCHHHHHCCCCCCCCCCCCCEEECCCCCHHHHCCCEEEECCCCCCCCCCHHHHHHHH
AAPIIVDDRVLAVLILHSRRSTTFTEEVLAFITTLCERAAHPLARAMSYQAAYETSYHLG
HCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVFSSLPIGLALLDLNGRVIRANPAWNQVWRLDAQPQRPSFYVGIDLVEHLLARLNDPFR
HHHHCCCCCEEEEECCCEEEECCCCCCHHEECCCCCCCCCEEEEHHHHHHHHHHCCCCCC
LSEFCDLGQRTPDQTFETSLQLRNPYQELHVLSVPTRDSQQQLTGRLWVVSDRTRERESD
HHHHHHCCCCCCCHHHHHHHHHCCCHHHCEEEECCCCCCHHHHCCEEEEEECCHHHHHHH
RLKDEFIGIVSHELRTPLTSILGYTEILLNRQDLDYESQREFLQTVSNEAERLFKMVKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LDVSRLEAGVVKLNRWAVGLWQVIEELTLQLHTQLIHHKLLIDARTPLPPVFADRDKVKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHH
IIFNLLSNAIKYSPEGSEIQLTVRRANADDLPATHPPGQWMLIVVRDEGIGIKPEDQARL
HHHHHHHHHHEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHH
FERFQRVDNSNTRQKSGVGLGLYISRLLVELHGGRIWVKSVEGSGSSFSFTLPIWTAPAN
HHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEECCCC
EQGQEP
CCCCCC
>Mature Secondary Structure 
THEPEDITTGYLSVLSAASRLLQEELPLVQRIHRLFGLLRLAIRYRDARLTCWLQSARP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
GAHRQQIFSPESWAYPWDDTLTRSVALGGKTVIKTIALGSAGQPDKNLPVIPAGYLGAPI
CCHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEECCHHCCCCE
FWGGRLWGVLELRNDDLRRFTGRISELIEALKPLLAAAIAQEGARLPQLPTPRFAGETPI
EECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GLTLTPSLRQKMIALNEQLDRTIDLHELTGVILRRALEGSGAEAGAVALVDYDKRELVLH
CEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHH
LYEGYEAERSRRALPALPRQRWSWEIGLAGQAVQMRRPLLVRDAGREPGLPNAMPFLAEL
HHHCCHHHHHCCCCCCCCCCCCCEEECCCCCHHHHCCCEEEECCCCCCCCCCHHHHHHHH
AAPIIVDDRVLAVLILHSRRSTTFTEEVLAFITTLCERAAHPLARAMSYQAAYETSYHLG
HCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVFSSLPIGLALLDLNGRVIRANPAWNQVWRLDAQPQRPSFYVGIDLVEHLLARLNDPFR
HHHHCCCCCEEEEECCCEEEECCCCCCHHEECCCCCCCCCEEEEHHHHHHHHHHCCCCCC
LSEFCDLGQRTPDQTFETSLQLRNPYQELHVLSVPTRDSQQQLTGRLWVVSDRTRERESD
HHHHHHCCCCCCCHHHHHHHHHCCCHHHCEEEECCCCCCHHHHCCEEEEEECCHHHHHHH
RLKDEFIGIVSHELRTPLTSILGYTEILLNRQDLDYESQREFLQTVSNEAERLFKMVKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LDVSRLEAGVVKLNRWAVGLWQVIEELTLQLHTQLIHHKLLIDARTPLPPVFADRDKVKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHH
IIFNLLSNAIKYSPEGSEIQLTVRRANADDLPATHPPGQWMLIVVRDEGIGIKPEDQARL
HHHHHHHHHHEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHH
FERFQRVDNSNTRQKSGVGLGLYISRLLVELHGGRIWVKSVEGSGSSFSFTLPIWTAPAN
HHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEECCCC
EQGQEP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]