Click here to switch to the map view.

The map label for this gene is rcsC [H]

Identifier: 222526275

GI number: 222526275

Start: 3751171

End: 3751524

Strand: Direct

Name: rcsC [H]

Synonym: Chy400_3041

Alternate gene names: 222526275

Gene position: 3751171-3751524 (Clockwise)

Preceding gene: 222526273

Following gene: 222526276

Centisome position: 71.19

GC content: 48.87

Gene sequence:

>354_bases
ATGCGCATCCTCATTGTAGAAGACGAAGCCAATGTGCGCTCTTTCTTGCAAAACGCAATGAAAGCATTGCGACGTGGTGT
GAAGGTTGATACGGCGAATCATGGTGCCGATGGCTTGAAACTGGCGCGTCGTCAATGGTACGACCTGATCATCACTGATT
ACCATATGCCAAAGATGGACGGCATCGATCTAACCTTCACCTTGCGCCAGGAAGGGTATACTATGCCGATTGTGATGATC
TCTGCTGATCCCATTGTTGAGCCGTATGCGTTAAATGCAGGCGCTAACCTCTTTCTGGCAAAGCCGGTAAGCCTGGAAAA
TCTCCGCTACATGCTTAATGTCTTTGGTCTGTAG

Upstream 100 bases:

>100_bases
AGCTTATTACAAAAAGATGAACCGAATGATGAACGCGGAAATTTGGCGATCTATCACGTTTTGTATAGTGACGTAAGACA
CAAAGTGAACGAGAGATACT

Downstream 100 bases:

>100_bases
GGTTTCCGAACACCAGATGAGTTCGATGGCAGACGTGCGACGCTTTAAATGTATCGCACGTCTGCTATTTGTGTGATACC
ATCTCTAGCGGTATGGCACG

Product: response regulator receiver protein

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MRILIVEDEANVRSFLQNAMKALRRGVKVDTANHGADGLKLARRQWYDLIITDYHMPKMDGIDLTFTLRQEGYTMPIVMI
SADPIVEPYALNAGANLFLAKPVSLENLRYMLNVFGL

Sequences:

>Translated_117_residues
MRILIVEDEANVRSFLQNAMKALRRGVKVDTANHGADGLKLARRQWYDLIITDYHMPKMDGIDLTFTLRQEGYTMPIVMI
SADPIVEPYALNAGANLFLAKPVSLENLRYMLNVFGL
>Mature_117_residues
MRILIVEDEANVRSFLQNAMKALRRGVKVDTANHGADGLKLARRQWYDLIITDYHMPKMDGIDLTFTLRQEGYTMPIVMI
SADPIVEPYALNAGANLFLAKPVSLENLRYMLNVFGL

Specific function: Member of the two-component regulatory system rcsC/rcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with rcsF, rcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=118, Percent_Identity=33.0508474576271, Blast_Score=73, Evalue=4e-15,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=34.7826086956522, Blast_Score=63, Evalue=4e-12,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=31.6239316239316, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1786784, Length=110, Percent_Identity=35.4545454545455, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI87082012, Length=110, Percent_Identity=34.5454545454545, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 13271; Mature: 13271

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIVEDEANVRSFLQNAMKALRRGVKVDTANHGADGLKLARRQWYDLIITDYHMPKMD
CEEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHEEEEECCCCCCCC
GIDLTFTLRQEGYTMPIVMISADPIVEPYALNAGANLFLAKPVSLENLRYMLNVFGL
CCEEEEEECCCCCEEEEEEEECCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRILIVEDEANVRSFLQNAMKALRRGVKVDTANHGADGLKLARRQWYDLIITDYHMPKMD
CEEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHEEEEECCCCCCCC
GIDLTFTLRQEGYTMPIVMISADPIVEPYALNAGANLFLAKPVSLENLRYMLNVFGL
CCEEEEEECCCCCEEEEEEEECCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504; 8626298 [H]