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The map label for this gene is prk [H]

Identifier: 222526270

GI number: 222526270

Start: 3744716

End: 3745576

Strand: Direct

Name: prk [H]

Synonym: Chy400_3036

Alternate gene names: 222526270

Gene position: 3744716-3745576 (Clockwise)

Preceding gene: 222526269

Following gene: 222526272

Centisome position: 71.07

GC content: 59.93

Gene sequence:

>861_bases
ATGCGAGAACATCCGCTTATGCTTGGGCTGGTTGGCGCCAGCGGCTCCGGGAAGACAACCCTGACCCAGGGGATTGTGCG
TCTGCTCGGTGCCCATGGCGTCACACCGGTCAATCTTGATGACTACCTGCGCTACAGTCGGGCTGAGCGTGCCGTGCGCG
GTATGACCGACGCCGATCCGGCGGCGATAGATTTGGATCGCATGGCGGCTGATCTGGTTGCGCTGCGGGCCGGTCGAACT
ATCGAGAAGCCGGTCTACGACCATACGATTGGTGCGCCACGGGGAAGTGAACGCGTTGCACCGACCGGCCTGGTTATTGC
CTATGGTGCGCTCACGCTTACCCCACCGGTGCAGGTTGAATTATTCGATTTGACTGTCTATTTTGATCCGCATCCTGCAC
TATACCGTCGCTGGCGGGAAGAGCGAGATGTTCTTCAGCGTGGGTATACGTTGGCTGAGGTGCAGGCCGCATGGCCGGCA
CGTGAACGTGACATTCAGCAGTACATCGTCGTGCAGCGTCCATTGGCCGATGTCGTTGTGCGTTTTGTGCCGGGGGAAAC
CGGCATTGACCTGCACCTGCTGTTGCGCCGCCGGGCATTGACGTTCGAGATGGCAGATGTTGGGCAGGAAACCGGATCAT
CGGCGGTGCAGATACAGCAGCTTGCGGCTGATGAGGATGGACTGCCGGCTGTGCTGGTCACCGCCACATCCGATCCCGCC
CTGGATCGCCTGAGTGAGGCATTGCGTGCGCGTTTACCGCGCAGTGGTCAGGTAACGGGTGACTCGCTCAACGCTACCCA
TCCAACGCTGCGATTTGCCCAAACGCTGATTGCGACGTTGCTCCTGCATAAATCGCTGTGA

Upstream 100 bases:

>100_bases
TAAGGTCTTGCAACAGGCGATGCGCCATCCGTTAACCGACCGCGGCATCGAGCAATTTCTGGCCGATTGGAAATCGCGCA
TGAGTTCCTGAGTTTACGCT

Downstream 100 bases:

>100_bases
CGTCAGGAACACGTTGTGGCCGGTATGAATGGGTAGGCGAAGGCATTGTCTTCGCCTACCGTATGCGGTGGTGTAACCGG
TAGTTTGTCGAAAAACCGGC

Product: phosphoribulokinase/uridine kinase

Products: NA

Alternate protein names: PRK; PRKase; Phosphopentokinase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MREHPLMLGLVGASGSGKTTLTQGIVRLLGAHGVTPVNLDDYLRYSRAERAVRGMTDADPAAIDLDRMAADLVALRAGRT
IEKPVYDHTIGAPRGSERVAPTGLVIAYGALTLTPPVQVELFDLTVYFDPHPALYRRWREERDVLQRGYTLAEVQAAWPA
RERDIQQYIVVQRPLADVVVRFVPGETGIDLHLLLRRRALTFEMADVGQETGSSAVQIQQLAADEDGLPAVLVTATSDPA
LDRLSEALRARLPRSGQVTGDSLNATHPTLRFAQTLIATLLLHKSL

Sequences:

>Translated_286_residues
MREHPLMLGLVGASGSGKTTLTQGIVRLLGAHGVTPVNLDDYLRYSRAERAVRGMTDADPAAIDLDRMAADLVALRAGRT
IEKPVYDHTIGAPRGSERVAPTGLVIAYGALTLTPPVQVELFDLTVYFDPHPALYRRWREERDVLQRGYTLAEVQAAWPA
RERDIQQYIVVQRPLADVVVRFVPGETGIDLHLLLRRRALTFEMADVGQETGSSAVQIQQLAADEDGLPAVLVTATSDPA
LDRLSEALRARLPRSGQVTGDSLNATHPTLRFAQTLIATLLLHKSL
>Mature_286_residues
MREHPLMLGLVGASGSGKTTLTQGIVRLLGAHGVTPVNLDDYLRYSRAERAVRGMTDADPAAIDLDRMAADLVALRAGRT
IEKPVYDHTIGAPRGSERVAPTGLVIAYGALTLTPPVQVELFDLTVYFDPHPALYRRWREERDVLQRGYTLAEVQAAWPA
RERDIQQYIVVQRPLADVVVRFVPGETGIDLHLLLRRRALTFEMADVGQETGSSAVQIQQLAADEDGLPAVLVTATSDPA
LDRLSEALRARLPRSGQVTGDSLNATHPTLRFAQTLIATLLLHKSL

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoribulokinase family [H]

Homologues:

Organism=Homo sapiens, GI57863312, Length=210, Percent_Identity=27.6190476190476, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI301129207, Length=210, Percent_Identity=27.6190476190476, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17539892, Length=264, Percent_Identity=26.1363636363636, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539894, Length=264, Percent_Identity=26.1363636363636, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573516, Length=200, Percent_Identity=28.5, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573514, Length=200, Percent_Identity=28.5, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573512, Length=200, Percent_Identity=28.5, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550449, Length=200, Percent_Identity=28.5, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006082
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.19 [H]

Molecular weight: Translated: 31280; Mature: 31280

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREHPLMLGLVGASGSGKTTLTQGIVRLLGAHGVTPVNLDDYLRYSRAERAVRGMTDADP
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
AAIDLDRMAADLVALRAGRTIEKPVYDHTIGAPRGSERVAPTGLVIAYGALTLTPPVQVE
CHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEEECCEEECCCCEEE
LFDLTVYFDPHPALYRRWREERDVLQRGYTLAEVQAAWPARERDIQQYIVVQRPLADVVV
EEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEHHHHCCCHHHHHHHHHHHHCCHHHHHH
RFVPGETGIDLHLLLRRRALTFEMADVGQETGSSAVQIQQLAADEDGLPAVLVTATSDPA
HHCCCCCCCHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHCCCCCCCEEEEEECCCHH
LDRLSEALRARLPRSGQVTGDSLNATHPTLRFAQTLIATLLLHKSL
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MREHPLMLGLVGASGSGKTTLTQGIVRLLGAHGVTPVNLDDYLRYSRAERAVRGMTDADP
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
AAIDLDRMAADLVALRAGRTIEKPVYDHTIGAPRGSERVAPTGLVIAYGALTLTPPVQVE
CHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEEECCEEECCCCEEE
LFDLTVYFDPHPALYRRWREERDVLQRGYTLAEVQAAWPARERDIQQYIVVQRPLADVVV
EEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEHHHHCCCHHHHHHHHHHHHCCHHHHHH
RFVPGETGIDLHLLLRRRALTFEMADVGQETGSSAVQIQQLAADEDGLPAVLVTATSDPA
HHCCCCCCCHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHCCCCCCCEEEEEECCCHH
LDRLSEALRARLPRSGQVTGDSLNATHPTLRFAQTLIATLLLHKSL
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1660882; 8905231 [H]