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The map label for this gene is appC [H]

Identifier: 222526245

GI number: 222526245

Start: 3716809

End: 3717690

Strand: Reverse

Name: appC [H]

Synonym: Chy400_3009

Alternate gene names: 222526245

Gene position: 3717690-3716809 (Counterclockwise)

Preceding gene: 222526246

Following gene: 222526244

Centisome position: 70.56

GC content: 49.21

Gene sequence:

>882_bases
ATGAAAGACTCACAATCACCCTGGTTCTTGTTCGTACAACGCTTTCGCAAGCATACTATGGCACTTGTCGGTATGGTCAT
TCTGGTAAGTATTACCATACTGGTTGCATTTGCGCCCTTCTTCACGACTCATGATCCGATGCAACAGAATCTGCTCAATC
GCTTTCAGCCACCATCAGCAACGCACTGGCTCGGCACTGATGATCTGGGACGTGATTTATGGGCACGCATCCTGTATGGT
GGACGTATTTCGTTGAGCGTTGGTCTGCTGGCAATGGCTGTGTCGATTACACTTGGTTCTCTCATCGGATTACTTGCGGG
ATATTTTGGCGGATGGGTTGATAGCGTGCTGATGAGGACAACAGAGATTTTTCTTTCTATTCCGCGATTATTTGTACTCA
TCGCATTGGGCATGTTTCTCCGTTCTCTCGACCTGTCAATGTTTCAGGCCGGTTCGTTCATACCTATCGCGCTAGTCATC
GGTTTGCTTTCCTGGATGGGAACTGCACGCATGGTACGCGCTTCTACCCTCACGGTGCGCGAACGCGAATACGTCCAGGC
ATGTCGGGCACTGGGAGGTTCACATCGCCGGATTCTACTTCGTCACATTTTGCCAAACATTGCCAGTCCGATCATCGTTT
CAGCAACGCTTGGACTCTCTGGTGCCATTATCAGTGAGAGTGGTCTTTCTTATCTTGGCTTTGGCGTACAGCTTCCCACA
CCTACCTGGGGGAATATGCTCTCTAATACCCAAAGTCAGATTACAACAGCACCCTGGGCGGCCATTTTTCCCGGTTTCAT
GATCTTCCTGGTAGTTATTTCAATTAATTATATTGGTGATGGTTTGCGTGATGCACTCGATCCGCGCCACCATTCACGCT
AG

Upstream 100 bases:

>100_bases
TGGTTATGGCTATTCTTACAATCTATTCTGCTCTGATAATCCTTTCCAACTTATTGGTTGATCTGATCTATGCCATGCTT
GATCCACGCATTCGACTGTC

Downstream 100 bases:

>100_bases
GAAATAACGTATGATGCAGGTCTTTCGTTCTTTGCTGACCAGGAATCTTCTCGCGTTACTTCTCGCTTTCTTTTTTATCA
TATCGGTGCAGGCACAATCA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKDSQSPWFLFVQRFRKHTMALVGMVILVSITILVAFAPFFTTHDPMQQNLLNRFQPPSATHWLGTDDLGRDLWARILYG
GRISLSVGLLAMAVSITLGSLIGLLAGYFGGWVDSVLMRTTEIFLSIPRLFVLIALGMFLRSLDLSMFQAGSFIPIALVI
GLLSWMGTARMVRASTLTVREREYVQACRALGGSHRRILLRHILPNIASPIIVSATLGLSGAIISESGLSYLGFGVQLPT
PTWGNMLSNTQSQITTAPWAAIFPGFMIFLVVISINYIGDGLRDALDPRHHSR

Sequences:

>Translated_293_residues
MKDSQSPWFLFVQRFRKHTMALVGMVILVSITILVAFAPFFTTHDPMQQNLLNRFQPPSATHWLGTDDLGRDLWARILYG
GRISLSVGLLAMAVSITLGSLIGLLAGYFGGWVDSVLMRTTEIFLSIPRLFVLIALGMFLRSLDLSMFQAGSFIPIALVI
GLLSWMGTARMVRASTLTVREREYVQACRALGGSHRRILLRHILPNIASPIIVSATLGLSGAIISESGLSYLGFGVQLPT
PTWGNMLSNTQSQITTAPWAAIFPGFMIFLVVISINYIGDGLRDALDPRHHSR
>Mature_293_residues
MKDSQSPWFLFVQRFRKHTMALVGMVILVSITILVAFAPFFTTHDPMQQNLLNRFQPPSATHWLGTDDLGRDLWARILYG
GRISLSVGLLAMAVSITLGSLIGLLAGYFGGWVDSVLMRTTEIFLSIPRLFVLIALGMFLRSLDLSMFQAGSFIPIALVI
GLLSWMGTARMVRASTLTVREREYVQACRALGGSHRRILLRHILPNIASPIIVSATLGLSGAIISESGLSYLGFGVQLPT
PTWGNMLSNTQSQITTAPWAAIFPGFMIFLVVISINYIGDGLRDALDPRHHSR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=286, Percent_Identity=36.7132867132867, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1787760, Length=283, Percent_Identity=36.3957597173145, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1787498, Length=291, Percent_Identity=37.4570446735395, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1789964, Length=290, Percent_Identity=37.9310344827586, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789889, Length=250, Percent_Identity=35.2, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1788505, Length=288, Percent_Identity=33.6805555555556, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787549, Length=284, Percent_Identity=32.7464788732394, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32261; Mature: 32261

Theoretical pI: Translated: 10.92; Mature: 10.92

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
>Mature Secondary Structure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CCHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]