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The map label for this gene is hypE [H]

Identifier: 222526224

GI number: 222526224

Start: 3691222

End: 3692277

Strand: Reverse

Name: hypE [H]

Synonym: Chy400_2986

Alternate gene names: 222526224

Gene position: 3692277-3691222 (Counterclockwise)

Preceding gene: 222526225

Following gene: 222526220

Centisome position: 70.08

GC content: 61.17

Gene sequence:

>1056_bases
ATGCACGAACCACTCGACTTCAGCGGCTGGACATGCCCGGCACCACTGCGCGACTACCCGACAGTTGTGATGGGCCACGG
TGCCGGCGGTAAGCTCTCCGCCGAACTGATCAATCATCTCTTCCTGCCGGCCTTTGGTCAACCTGCTCGCCCACTGGCCG
ACGCGGCCATCACCGAGATTGGCAATAGCCGTCTGGCCATCTCCACCGACAGCTTCGTCGTGCGACCGCTTTTCTTTCCA
GGGGGCAACATCGGCGAACTGGCCGTCAACGGCACGATCAACGACATTGCCATGATGGGAGCGCAGCCCCTGGCGCTGAC
CGCTAGCTTCATTCTGGAAGAGGGCATGCCACTGTCGCAACTCGGCGTAATTGCCGAGAGCATGGGACGTGCCGCCCGTC
AGGCCGGCGTCACCCTGATTGCCGGCGACACCAAAGTTGTTGACCGTGGTCACGGTGATGGAGTCTACATCACGACAACC
GGTTTCGGCCTCATTCCGGCAGGCGTAACGATTGGCCCGGAACAGGCCCGTCCCGGTGATGCGATCATTGTCAGCGGAGC
CATTGGCGTGCACGGTGTCGCCATCCTGAGCGTGCGCGAAGGGATTGAATTCGGCGCCCCGGTCGTCTCCGACACGGCTG
CCCTGCACGATCTGGTACGCACAATGATTGCCAGTGGCGCACGCATTCACACACTCCGCGATCCGACACGGGGTGGCGTT
GCGGCAGCACTCAACGAAATTGCCCAAACCGCCGGGATCGGAGTTGAGATTGTCGAACGTGACATTCCCATTCCACCCGC
AGTCCAGGCCGCCTGCGAGTTACTCGGTATGGATCCATTACACATTGCCAACGAAGGCAAACTGATTACCTTCGTCGAAC
GCAGTGATGCCGAACACCTGCTGAGCGTCATGCGATCACATCCATTGGGGCGCGAGGCTGCCCTGATCGGCTATGCAACC
GCCGATCATCCCGGCGTCGTGGTTGCCCGCACCGGCATTGGTGGCACGCGCGTCGTTGACACCTTGATCGGCGAGCAACT
GCCACGCATTTGTTGA

Upstream 100 bases:

>100_bases
GCTTCATTCCGGTTAACCAGGTTGGCGTGACCGGCTAACGCTACCGGCATCACGATACGCTGATCGCCATAGTACACAGA
AACCATAGCGGACAATGCCT

Downstream 100 bases:

>100_bases
GCGCATTGGCTGCGATACAGAAGATCGCCGGATGGGGCAGGTGAAGGCAATGCCTTCGCCTGCTTCTTTATATCAATGAC
ACCAAATCAAATGGTATAGA

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MHEPLDFSGWTCPAPLRDYPTVVMGHGAGGKLSAELINHLFLPAFGQPARPLADAAITEIGNSRLAISTDSFVVRPLFFP
GGNIGELAVNGTINDIAMMGAQPLALTASFILEEGMPLSQLGVIAESMGRAARQAGVTLIAGDTKVVDRGHGDGVYITTT
GFGLIPAGVTIGPEQARPGDAIIVSGAIGVHGVAILSVREGIEFGAPVVSDTAALHDLVRTMIASGARIHTLRDPTRGGV
AAALNEIAQTAGIGVEIVERDIPIPPAVQAACELLGMDPLHIANEGKLITFVERSDAEHLLSVMRSHPLGREAALIGYAT
ADHPGVVVARTGIGGTRVVDTLIGEQLPRIC

Sequences:

>Translated_351_residues
MHEPLDFSGWTCPAPLRDYPTVVMGHGAGGKLSAELINHLFLPAFGQPARPLADAAITEIGNSRLAISTDSFVVRPLFFP
GGNIGELAVNGTINDIAMMGAQPLALTASFILEEGMPLSQLGVIAESMGRAARQAGVTLIAGDTKVVDRGHGDGVYITTT
GFGLIPAGVTIGPEQARPGDAIIVSGAIGVHGVAILSVREGIEFGAPVVSDTAALHDLVRTMIASGARIHTLRDPTRGGV
AAALNEIAQTAGIGVEIVERDIPIPPAVQAACELLGMDPLHIANEGKLITFVERSDAEHLLSVMRSHPLGREAALIGYAT
ADHPGVVVARTGIGGTRVVDTLIGEQLPRIC
>Mature_351_residues
MHEPLDFSGWTCPAPLRDYPTVVMGHGAGGKLSAELINHLFLPAFGQPARPLADAAITEIGNSRLAISTDSFVVRPLFFP
GGNIGELAVNGTINDIAMMGAQPLALTASFILEEGMPLSQLGVIAESMGRAARQAGVTLIAGDTKVVDRGHGDGVYITTT
GFGLIPAGVTIGPEQARPGDAIIVSGAIGVHGVAILSVREGIEFGAPVVSDTAALHDLVRTMIASGARIHTLRDPTRGGV
AAALNEIAQTAGIGVEIVERDIPIPPAVQAACELLGMDPLHIANEGKLITFVERSDAEHLLSVMRSHPLGREAALIGYAT
ADHPGVVVARTGIGGTRVVDTLIGEQLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=343, Percent_Identity=44.8979591836735, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36312; Mature: 36312

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEPLDFSGWTCPAPLRDYPTVVMGHGAGGKLSAELINHLFLPAFGQPARPLADAAITEI
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
GNSRLAISTDSFVVRPLFFPGGNIGELAVNGTINDIAMMGAQPLALTASFILEEGMPLSQ
CCCEEEEECCCEEEEEEECCCCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHCCCCHHH
LGVIAESMGRAARQAGVTLIAGDTKVVDRGHGDGVYITTTGFGLIPAGVTIGPEQARPGD
HHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCEEEEEECCCEEECCCEEECCCCCCCCC
AIIVSGAIGVHGVAILSVREGIEFGAPVVSDTAALHDLVRTMIASGARIHTLRDPTRGGV
EEEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCH
AAALNEIAQTAGIGVEIVERDIPIPPAVQAACELLGMDPLHIANEGKLITFVERSDAEHL
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCEEEEEECCCHHHH
LSVMRSHPLGREAALIGYATADHPGVVVARTGIGGTRVVDTLIGEQLPRIC
HHHHHCCCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHEPLDFSGWTCPAPLRDYPTVVMGHGAGGKLSAELINHLFLPAFGQPARPLADAAITEI
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
GNSRLAISTDSFVVRPLFFPGGNIGELAVNGTINDIAMMGAQPLALTASFILEEGMPLSQ
CCCEEEEECCCEEEEEEECCCCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHCCCCHHH
LGVIAESMGRAARQAGVTLIAGDTKVVDRGHGDGVYITTTGFGLIPAGVTIGPEQARPGD
HHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCEEEEEECCCEEECCCEEECCCCCCCCC
AIIVSGAIGVHGVAILSVREGIEFGAPVVSDTAALHDLVRTMIASGARIHTLRDPTRGGV
EEEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCH
AAALNEIAQTAGIGVEIVERDIPIPPAVQAACELLGMDPLHIANEGKLITFVERSDAEHL
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCEEEEEECCCHHHH
LSVMRSHPLGREAALIGYATADHPGVVVARTGIGGTRVVDTLIGEQLPRIC
HHHHHCCCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8510650; 7906310; 12597275 [H]