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The map label for this gene is yciC [H]

Identifier: 222526208

GI number: 222526208

Start: 3666469

End: 3667383

Strand: Reverse

Name: yciC [H]

Synonym: Chy400_2969

Alternate gene names: 222526208

Gene position: 3667383-3666469 (Counterclockwise)

Preceding gene: 222526209

Following gene: 222526203

Centisome position: 69.6

GC content: 58.25

Gene sequence:

>915_bases
ATGCTGATGGACAATAACATACCAACAATTCCGGTCACTATCATCAGCGGTTTTCTCGGCAGTGGCAAAACGACACTGTT
GCGCCGCCTGCTGAGTCGTGGCGATCAGCGAATTGGAGTGATCGTCAACGAATTCGGCACGTTGGGCATTGACGGCGAAC
TGTTAGCACAGAGTGGCGCTGCGCCACTGATCGAATTGAACGGTGGCTGTGTCTGTTGCGTCGCCGGTAGTGACCTGCTC
CTCGCGCTTGAAACCCTGTTCGCCAGTGGGCCACTGTCAGCCATCGCAATTGAAACGAGTGGTCTTGCCGAGCCGGGCGC
ATTGATCCGACAGCTTCGCGCTGCCGATATTCCACTCGATACACTGGTTACCCTCGTCTCAGCCGTTGATTACGAGCAGG
CGATGACGGCCTCGCCACTCACACTGCGCCAGATACACCTCGCCGATTTGATCCTGATCACCCACAGCGACCTGGTTTCT
GCGCAAACCATTGCACAGATCAGTGAGCAACTGCGCACAATCAACCGGCGGGCACCGCTTGTCCCAATCGTCCAGGGTGA
TGTGCCACCGACGCTGATCTTCAGCCCACGCTACGATGGCACACTACCTGCCGAAAGTCCACACCTGCACGACGAATTTG
CCGTCACGAGCTGGCAAACCGATCTACCATTACAACGCACTGCGCTCGAACAGACCCTGCGCAGACTGGCAGCCGATGGT
ATCTATCGGGCCAAGGGCATCGTATACTGCACCGACTCACCCTGGGCAGACGAAGTCCATCTGGTCGCCGAACGCTTGAC
TCTGAGCGCATTACGCCTCTCTACCCAACCCCGACCGCTCTGTCGCCTCACCCCTGATCGGGCGCGCCGCAGCGCTGGAA
CCGGCAGCCAATGCGTTAGACTCCTGCATCGATAG

Upstream 100 bases:

>100_bases
CTGCAAGATCAAGAGCTACCCACGGCGGTCGTCTATTGGGAGGGCGCGGTGGATGTAGAGGGTAGTATGCGCGGTCGTGG
TTATGTCGAGTTAACCGGTT

Downstream 100 bases:

>100_bases
CGACGAGCGGATTACCCGATGGCAACAGCGGTTAGCCGGGCAGATGTAGCAGATTGATCGTCGCAATTGTCCGACCAGCC
TCGGATTCGATCATCACCAG

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLMDNNIPTIPVTIISGFLGSGKTTLLRRLLSRGDQRIGVIVNEFGTLGIDGELLAQSGAAPLIELNGGCVCCVAGSDLL
LALETLFASGPLSAIAIETSGLAEPGALIRQLRAADIPLDTLVTLVSAVDYEQAMTASPLTLRQIHLADLILITHSDLVS
AQTIAQISEQLRTINRRAPLVPIVQGDVPPTLIFSPRYDGTLPAESPHLHDEFAVTSWQTDLPLQRTALEQTLRRLAADG
IYRAKGIVYCTDSPWADEVHLVAERLTLSALRLSTQPRPLCRLTPDRARRSAGTGSQCVRLLHR

Sequences:

>Translated_304_residues
MLMDNNIPTIPVTIISGFLGSGKTTLLRRLLSRGDQRIGVIVNEFGTLGIDGELLAQSGAAPLIELNGGCVCCVAGSDLL
LALETLFASGPLSAIAIETSGLAEPGALIRQLRAADIPLDTLVTLVSAVDYEQAMTASPLTLRQIHLADLILITHSDLVS
AQTIAQISEQLRTINRRAPLVPIVQGDVPPTLIFSPRYDGTLPAESPHLHDEFAVTSWQTDLPLQRTALEQTLRRLAADG
IYRAKGIVYCTDSPWADEVHLVAERLTLSALRLSTQPRPLCRLTPDRARRSAGTGSQCVRLLHR
>Mature_304_residues
MLMDNNIPTIPVTIISGFLGSGKTTLLRRLLSRGDQRIGVIVNEFGTLGIDGELLAQSGAAPLIELNGGCVCCVAGSDLL
LALETLFASGPLSAIAIETSGLAEPGALIRQLRAADIPLDTLVTLVSAVDYEQAMTASPLTLRQIHLADLILITHSDLVS
AQTIAQISEQLRTINRRAPLVPIVQGDVPPTLIFSPRYDGTLPAESPHLHDEFAVTSWQTDLPLQRTALEQTLRRLAADG
IYRAKGIVYCTDSPWADEVHLVAERLTLSALRLSTQPRPLCRLTPDRARRSAGTGSQCVRLLHR

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI223941779, Length=272, Percent_Identity=30.5147058823529, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI33469141, Length=183, Percent_Identity=38.2513661202186, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI126722884, Length=183, Percent_Identity=38.2513661202186, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI146231952, Length=183, Percent_Identity=38.2513661202186, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI148727351, Length=183, Percent_Identity=37.7049180327869, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI223941776, Length=173, Percent_Identity=35.8381502890173, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI119120938, Length=130, Percent_Identity=40, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI87082430, Length=291, Percent_Identity=28.1786941580756, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788499, Length=250, Percent_Identity=32, Blast_Score=95, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6324356, Length=212, Percent_Identity=30.188679245283, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 32757; Mature: 32757

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMDNNIPTIPVTIISGFLGSGKTTLLRRLLSRGDQRIGVIVNEFGTLGIDGELLAQSGA
CCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCC
APLIELNGGCVCCVAGSDLLLALETLFASGPLSAIAIETSGLAEPGALIRQLRAADIPLD
CCEEEECCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHH
TLVTLVSAVDYEQAMTASPLTLRQIHLADLILITHSDLVSAQTIAQISEQLRTINRRAPL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCE
VPIVQGDVPPTLIFSPRYDGTLPAESPHLHDEFAVTSWQTDLPLQRTALEQTLRRLAADG
EEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCC
IYRAKGIVYCTDSPWADEVHLVAERLTLSALRLSTQPRPLCRLTPDRARRSAGTGSQCVR
HHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHCCCCHHHHHH
LLHR
HHCC
>Mature Secondary Structure
MLMDNNIPTIPVTIISGFLGSGKTTLLRRLLSRGDQRIGVIVNEFGTLGIDGELLAQSGA
CCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCC
APLIELNGGCVCCVAGSDLLLALETLFASGPLSAIAIETSGLAEPGALIRQLRAADIPLD
CCEEEECCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHH
TLVTLVSAVDYEQAMTASPLTLRQIHLADLILITHSDLVSAQTIAQISEQLRTINRRAPL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCE
VPIVQGDVPPTLIFSPRYDGTLPAESPHLHDEFAVTSWQTDLPLQRTALEQTLRRLAADG
EEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCC
IYRAKGIVYCTDSPWADEVHLVAERLTLSALRLSTQPRPLCRLTPDRARRSAGTGSQCVR
HHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHCCCCHHHHHH
LLHR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]