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The map label for this gene is groL1

Identifier: 222526201

GI number: 222526201

Start: 3657460

End: 3659094

Strand: Reverse

Name: groL1

Synonym: Chy400_2960

Alternate gene names: 222526201

Gene position: 3659094-3657460 (Counterclockwise)

Preceding gene: 222526202

Following gene: 222526200

Centisome position: 69.45

GC content: 60.37

Gene sequence:

>1635_bases
ATGCCAAAGCAGCTTTATTTCAACGAAGAGGCACGCCGTGCCCTGAAGCGTGGTGTAGACCTGGTTGCTGATGCGGTAAA
GACCACGCTCGGCCCGCGCGGTCGCAATGTGGCAATTGACAAGAAGTTTGGTTCGCCGACGGTAACCCACGACGGTGTGA
CGGTCGCGAAGGAGATCGAGCTGAAGGATCCCTTCGAGAACATGGGTGCGCAACTGCTCAAGGAGGCTGCGACCAAGACC
AACGATGTGGCCGGTGACGGTACCACCACGGCGACGGTGCTGGCTCAGGCCATCGTCACCGAGGGTCTGAAGGTAGTAGC
CGCCGGCGCCAACGCCATGCTGCTCAAGCGTGGTCTTGATCGCGGTGCCGAGGCCCTGGTAGCCGCTATCAAGGCGAGTG
CCGTACCGGTTCGCGACCGCGCCGACATTGCCCACGTTGCCACCAACTCGGCGGCTGACAGCGAAATTGGTGAGCTGATC
GCCGAAGTGATGGAGAAGGTTGGCAAGGACGGTGTGATCACCGTTGAAGAGTCGAAGGGCGTTACCTTCGAGAAGGAATA
CACCGAAGGTATGCAGTTCGACCGGGGCTACATTTCGGGTTACATGGTCACCAACGTCGAACGCCAGGAAGCCGAGCTTG
ATGAACCGTACATCCTGATTACTGACAAGAAGATTAGCAGCATTCAGGAAATCCTGCCGGTGCTCGAGAAGGTGTTGCAG
GTGACGAAGAACTTCGTCATCATCGCTGAAGACGTTGATGGCGAAGCGCTGGCGACGCTGGTGGTCAACAAGCTGCGTGG
CACGATCAATGCCCTGGCCGTCAAGGCGCCTGGCTTCGGTGATCGCCGCAAGGCCATGCTGCAGGACATTGCTATTCTCA
CCGGTGGCACCGTCATCAGCGAGGAGATTGGCCGCAAGCTCGATAGCGCCACTATCGAGGACCTGGGCCGCGCGCGCAAG
GTGATTGCAACCAAGGATGACACGACGATTATCGAGGGCCGTGGCGATGAGGCGGCGATCCGCGCCCGCATCGAGCAGAT
CCGCGCCCAGATTGCAACCACCACCAGTGACTTTGATCGCGAGAAGCTGCAAGAGCGGCTGGCCAAGCTGGCCGGTGGTG
TGGCCGTGATCAAGGTCGGTGCTGCGACCGAGCCTGAGCTGAAGGAGAAGAAGCACCGCGTTGAGGACGCCCTGAGTGCA
ACCCGTGCTGCCGTTGAAGAGGGTATCGTGCCCGGTGGTGGTGTCGCGCTGATCAACGCTATTCCGGCGCTCGACAACGT
GCAGGTTGCTCACGAAGACGAGAAGGTTGGTCTCCAGATTCTGCGCCGTGCGCTCGAGGAGCCGCTGCGCATCCTGGCCC
GCAACGCCGGTGAGGACGGTTCGGTGATTATCGCCAATGTCCGCCGCCTGCAAGAGGAGAAGGGTGACAAGACCATCGGT
TACAACGTGCTGACCGGTCAGTATGGCAGCATGATCGAGCAGGGCATCATCGACCCGGTGAAGGTCACCCGCAGCGCTGT
ACAGAACGCGGTTTCGATTGCCGGTATGATCCTGACCACCGAGGCGCTGATTACCGACATTCCTGAGGACAAGCCGGCGG
CAACTCCGGGCGCCGGTGGCGGGATGGACTTCTAA

Upstream 100 bases:

>100_bases
TCGAGTACCTGATCCTGTCGGAGAAGGACATTCTGGGTATCGTTCAGGAGTAACAACGTCGCGCAAGTAGCGCTATTCTC
AAGGGAGGATTATAGATCCT

Downstream 100 bases:

>100_bases
GGTTCCAGCGCTACGATAGTACGACAGGGGTGTACGAACGTGCACCCCTGTTTGTTTTTGGTTTGCGCATAGATGTGTAT
CACTTGGGCTGTCAGATCCG

Product: chaperonin GroEL

Products: NA

Alternate protein names: GroEL protein 1; Protein Cpn60 1

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MPKQLYFNEEARRALKRGVDLVADAVKTTLGPRGRNVAIDKKFGSPTVTHDGVTVAKEIELKDPFENMGAQLLKEAATKT
NDVAGDGTTTATVLAQAIVTEGLKVVAAGANAMLLKRGLDRGAEALVAAIKASAVPVRDRADIAHVATNSAADSEIGELI
AEVMEKVGKDGVITVEESKGVTFEKEYTEGMQFDRGYISGYMVTNVERQEAELDEPYILITDKKISSIQEILPVLEKVLQ
VTKNFVIIAEDVDGEALATLVVNKLRGTINALAVKAPGFGDRRKAMLQDIAILTGGTVISEEIGRKLDSATIEDLGRARK
VIATKDDTTIIEGRGDEAAIRARIEQIRAQIATTTSDFDREKLQERLAKLAGGVAVIKVGAATEPELKEKKHRVEDALSA
TRAAVEEGIVPGGGVALINAIPALDNVQVAHEDEKVGLQILRRALEEPLRILARNAGEDGSVIIANVRRLQEEKGDKTIG
YNVLTGQYGSMIEQGIIDPVKVTRSAVQNAVSIAGMILTTEALITDIPEDKPAATPGAGGGMDF

Sequences:

>Translated_544_residues
MPKQLYFNEEARRALKRGVDLVADAVKTTLGPRGRNVAIDKKFGSPTVTHDGVTVAKEIELKDPFENMGAQLLKEAATKT
NDVAGDGTTTATVLAQAIVTEGLKVVAAGANAMLLKRGLDRGAEALVAAIKASAVPVRDRADIAHVATNSAADSEIGELI
AEVMEKVGKDGVITVEESKGVTFEKEYTEGMQFDRGYISGYMVTNVERQEAELDEPYILITDKKISSIQEILPVLEKVLQ
VTKNFVIIAEDVDGEALATLVVNKLRGTINALAVKAPGFGDRRKAMLQDIAILTGGTVISEEIGRKLDSATIEDLGRARK
VIATKDDTTIIEGRGDEAAIRARIEQIRAQIATTTSDFDREKLQERLAKLAGGVAVIKVGAATEPELKEKKHRVEDALSA
TRAAVEEGIVPGGGVALINAIPALDNVQVAHEDEKVGLQILRRALEEPLRILARNAGEDGSVIIANVRRLQEEKGDKTIG
YNVLTGQYGSMIEQGIIDPVKVTRSAVQNAVSIAGMILTTEALITDIPEDKPAATPGAGGGMDF
>Mature_543_residues
PKQLYFNEEARRALKRGVDLVADAVKTTLGPRGRNVAIDKKFGSPTVTHDGVTVAKEIELKDPFENMGAQLLKEAATKTN
DVAGDGTTTATVLAQAIVTEGLKVVAAGANAMLLKRGLDRGAEALVAAIKASAVPVRDRADIAHVATNSAADSEIGELIA
EVMEKVGKDGVITVEESKGVTFEKEYTEGMQFDRGYISGYMVTNVERQEAELDEPYILITDKKISSIQEILPVLEKVLQV
TKNFVIIAEDVDGEALATLVVNKLRGTINALAVKAPGFGDRRKAMLQDIAILTGGTVISEEIGRKLDSATIEDLGRARKV
IATKDDTTIIEGRGDEAAIRARIEQIRAQIATTTSDFDREKLQERLAKLAGGVAVIKVGAATEPELKEKKHRVEDALSAT
RAAVEEGIVPGGGVALINAIPALDNVQVAHEDEKVGLQILRRALEEPLRILARNAGEDGSVIIANVRRLQEEKGDKTIGY
NVLTGQYGSMIEQGIIDPVKVTRSAVQNAVSIAGMILTTEALITDIPEDKPAATPGAGGGMDF

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family

Homologues:

Organism=Homo sapiens, GI41399285, Length=531, Percent_Identity=49.3408662900188, Blast_Score=504, Evalue=1e-142,
Organism=Homo sapiens, GI31542947, Length=531, Percent_Identity=49.3408662900188, Blast_Score=504, Evalue=1e-142,
Organism=Homo sapiens, GI38455427, Length=554, Percent_Identity=23.4657039711191, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790586, Length=532, Percent_Identity=61.0902255639098, Blast_Score=629, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17555558, Length=531, Percent_Identity=48.0225988700565, Blast_Score=488, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI193210679, Length=214, Percent_Identity=49.0654205607477, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17532603, Length=535, Percent_Identity=22.9906542056075, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323288, Length=527, Percent_Identity=52.9411764705882, Blast_Score=518, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6322350, Length=529, Percent_Identity=22.4952741020794, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322524, Length=125, Percent_Identity=30.4, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24641193, Length=530, Percent_Identity=50, Blast_Score=506, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24641191, Length=530, Percent_Identity=50, Blast_Score=506, Evalue=1e-143,
Organism=Drosophila melanogaster, GI45550936, Length=528, Percent_Identity=46.969696969697, Blast_Score=478, Evalue=1e-135,
Organism=Drosophila melanogaster, GI45550132, Length=528, Percent_Identity=46.969696969697, Blast_Score=478, Evalue=1e-135,
Organism=Drosophila melanogaster, GI45550935, Length=528, Percent_Identity=46.969696969697, Blast_Score=478, Evalue=1e-135,
Organism=Drosophila melanogaster, GI17864606, Length=545, Percent_Identity=40.9174311926606, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24584129, Length=532, Percent_Identity=37.0300751879699, Blast_Score=308, Evalue=8e-84,
Organism=Drosophila melanogaster, GI19921262, Length=532, Percent_Identity=37.0300751879699, Blast_Score=308, Evalue=8e-84,
Organism=Drosophila melanogaster, GI24583944, Length=519, Percent_Identity=23.8921001926782, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): CH601_CHLAA (A9WJN7)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636330.1
- GeneID:   5827207
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_2736
- HOGENOM:   HBG625289
- OMA:   ENTTLAM
- ProtClustDB:   CLSK2516915
- GO:   GO:0005737
- HAMAP:   MF_00600
- InterPro:   IPR018370
- InterPro:   IPR001844
- InterPro:   IPR002423
- PANTHER:   PTHR11353
- PRINTS:   PR00298
- TIGRFAMs:   TIGR02348

Pfam domain/function: PF00118 Cpn60_TCP1; SSF48592 GroEL-ATPase

EC number: NA

Molecular weight: Translated: 58021; Mature: 57890

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKQLYFNEEARRALKRGVDLVADAVKTTLGPRGRNVAIDKKFGSPTVTHDGVTVAKEIE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCEEEEEEC
LKDPFENMGAQLLKEAATKTNDVAGDGTTTATVLAQAIVTEGLKVVAAGANAMLLKRGLD
CCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCC
RGAEALVAAIKASAVPVRDRADIAHVATNSAADSEIGELIAEVMEKVGKDGVITVEESKG
HHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCC
VTFEKEYTEGMQFDRGYISGYMVTNVERQEAELDEPYILITDKKISSIQEILPVLEKVLQ
CEEEHHHHCCCCCCCHHHCCEEEECCCHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHH
VTKNFVIIAEDVDGEALATLVVNKLRGTINALAVKAPGFGDRRKAMLQDIAILTGGTVIS
HHCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCHHHH
EEIGRKLDSATIEDLGRARKVIATKDDTTIIEGRGDEAAIRARIEQIRAQIATTTSDFDR
HHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHH
EKLQERLAKLAGGVAVIKVGAATEPELKEKKHRVEDALSATRAAVEEGIVPGGGVALINA
HHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
IPALDNVQVAHEDEKVGLQILRRALEEPLRILARNAGEDGSVIIANVRRLQEEKGDKTIG
HCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCEEC
YNVLTGQYGSMIEQGIIDPVKVTRSAVQNAVSIAGMILTTEALITDIPEDKPAATPGAGG
CEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GMDF
CCCC
>Mature Secondary Structure 
PKQLYFNEEARRALKRGVDLVADAVKTTLGPRGRNVAIDKKFGSPTVTHDGVTVAKEIE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCEEEEEEC
LKDPFENMGAQLLKEAATKTNDVAGDGTTTATVLAQAIVTEGLKVVAAGANAMLLKRGLD
CCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCC
RGAEALVAAIKASAVPVRDRADIAHVATNSAADSEIGELIAEVMEKVGKDGVITVEESKG
HHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCC
VTFEKEYTEGMQFDRGYISGYMVTNVERQEAELDEPYILITDKKISSIQEILPVLEKVLQ
CEEEHHHHCCCCCCCHHHCCEEEECCCHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHH
VTKNFVIIAEDVDGEALATLVVNKLRGTINALAVKAPGFGDRRKAMLQDIAILTGGTVIS
HHCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCHHHH
EEIGRKLDSATIEDLGRARKVIATKDDTTIIEGRGDEAAIRARIEQIRAQIATTTSDFDR
HHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHH
EKLQERLAKLAGGVAVIKVGAATEPELKEKKHRVEDALSATRAAVEEGIVPGGGVALINA
HHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
IPALDNVQVAHEDEKVGLQILRRALEEPLRILARNAGEDGSVIIANVRRLQEEKGDKTIG
HCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCEEC
YNVLTGQYGSMIEQGIIDPVKVTRSAVQNAVSIAGMILTTEALITDIPEDKPAATPGAGG
CEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GMDF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA