Click here to switch to the map view.

The map label for this gene is rsbRB [H]

Identifier: 222526199

GI number: 222526199

Start: 3654748

End: 3655827

Strand: Direct

Name: rsbRB [H]

Synonym: Chy400_2958

Alternate gene names: 222526199

Gene position: 3654748-3655827 (Clockwise)

Preceding gene: 222526198

Following gene: 222526204

Centisome position: 69.36

GC content: 58.06

Gene sequence:

>1080_bases
ATGAGCGAATCAACCATTTCCATCCTTACCCTCGAACAGGTTCGCCAGCTCCGGCGCTTTTTTCTCTGGGTAGCCGGAAT
TGTCGGGATTGTCGCAATCGTTGCGACAGTGTCTGCGGCAATCTGGCGCACTCCCACCCTGATTGCGCTCATGATCCTGG
ATTGGGTATTGGTGGTTGGCCTCTTACAGGCATGGGCACAGACGCGCAGCGGTCAGGTGCGCGTCGCGTTAATGACTTCG
TTTATTGCCCTCGTTCTGTATGGGCTATTCGGGGCGGTTATCTTGCCGAATGTGGCCTCGCTGATGGCATTTGCCCCTGT
GCTGGCAATTGTCGCCATGCTGCCATTTCTGAGCGGAGTTGTGCTCAGGCGCTTGCTGATCGTGGCCTGGATTGCCGTTG
TTGTCACGATAGTACTGGGTTCGCAAGTCCGTCTCTTTCCGCCTATTCCCGAGGTTCTGGAACTACCGTTTCAGTTTGCC
GGTGTGTTGGGGATCAGCGCAATCCTGTTATTACAGCTCTGGCTCTTTCACGAGCGCCTGCTAGGAGTTATCACACAATT
GCGGCAGACCAACGCGGCGCTTGAGCAGGAGCGTACCGGCTTGCAGGAACGCGTTGCCCAACGGACGGCTGATTTGCAGC
AGGCGTTAGCCGAAGTTGAGCGACAAATGGCCGAACAATCGCGCCTACTGGCCGAAAATGAGCGTCAGCGCGAGCTGATC
CGTGGTTTGAGTATGCCGGTGCTGCCGGTTTCTCAGGAAACCCTGGTAATGCCCCTGGTTGGTGAGCTTGATGCCGAACG
GATCGCGGTGGCGCAGGCGACAGCGCTTCAAGCGATTGATCGGGCCGATGCCCGCCATCTGGTGCTTGACATTACCGGGA
TGCCGTTTGTTGACACAACGGTTGCTGCCGGTCTGATGCAACTGGTGCAGTCGGCCCGCTTGCTGGGGGCAACAGTGACC
CTGGTTGGTGTGCGTCCAGAAGTTGCGCAGACGATTGTAGCGCTGGGGATCGACCTGTCTGAGGTAACGACCGCCGCCGA
CCTTGCCTCTGCGCTACGGCGTCAGCGAGTGACAGCGTAG

Upstream 100 bases:

>100_bases
GAAAAGCCCGACTGACATGCGTTTGTTAAGATATGGTAGGATGGCGTACTGAGCATTGCTGCAAACAACGCAGATCGCAT
TCACGTGAGGAAGAGTTCAC

Downstream 100 bases:

>100_bases
GCACCGGTTGAAAGCAACGCCCAAACGCTCATACTGCCTGCCCTGTCTCAGCCCCTATCAGAATTTCTCGACAGGTATGG
ATCGGTTGCCCCCGCATGCG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRB [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSESTISILTLEQVRQLRRFFLWVAGIVGIVAIVATVSAAIWRTPTLIALMILDWVLVVGLLQAWAQTRSGQVRVALMTS
FIALVLYGLFGAVILPNVASLMAFAPVLAIVAMLPFLSGVVLRRLLIVAWIAVVVTIVLGSQVRLFPPIPEVLELPFQFA
GVLGISAILLLQLWLFHERLLGVITQLRQTNAALEQERTGLQERVAQRTADLQQALAEVERQMAEQSRLLAENERQRELI
RGLSMPVLPVSQETLVMPLVGELDAERIAVAQATALQAIDRADARHLVLDITGMPFVDTTVAAGLMQLVQSARLLGATVT
LVGVRPEVAQTIVALGIDLSEVTTAADLASALRRQRVTA

Sequences:

>Translated_359_residues
MSESTISILTLEQVRQLRRFFLWVAGIVGIVAIVATVSAAIWRTPTLIALMILDWVLVVGLLQAWAQTRSGQVRVALMTS
FIALVLYGLFGAVILPNVASLMAFAPVLAIVAMLPFLSGVVLRRLLIVAWIAVVVTIVLGSQVRLFPPIPEVLELPFQFA
GVLGISAILLLQLWLFHERLLGVITQLRQTNAALEQERTGLQERVAQRTADLQQALAEVERQMAEQSRLLAENERQRELI
RGLSMPVLPVSQETLVMPLVGELDAERIAVAQATALQAIDRADARHLVLDITGMPFVDTTVAAGLMQLVQSARLLGATVT
LVGVRPEVAQTIVALGIDLSEVTTAADLASALRRQRVTA
>Mature_358_residues
SESTISILTLEQVRQLRRFFLWVAGIVGIVAIVATVSAAIWRTPTLIALMILDWVLVVGLLQAWAQTRSGQVRVALMTSF
IALVLYGLFGAVILPNVASLMAFAPVLAIVAMLPFLSGVVLRRLLIVAWIAVVVTIVLGSQVRLFPPIPEVLELPFQFAG
VLGISAILLLQLWLFHERLLGVITQLRQTNAALEQERTGLQERVAQRTADLQQALAEVERQMAEQSRLLAENERQRELIR
GLSMPVLPVSQETLVMPLVGELDAERIAVAQATALQAIDRADARHLVLDITGMPFVDTTVAAGLMQLVQSARLLGATVTL
VGVRPEVAQTIVALGIDLSEVTTAADLASALRRQRVTA

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39015; Mature: 38884

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESTISILTLEQVRQLRRFFLWVAGIVGIVAIVATVSAAIWRTPTLIALMILDWVLVVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LLQAWAQTRSGQVRVALMTSFIALVLYGLFGAVILPNVASLMAFAPVLAIVAMLPFLSGV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLRRLLIVAWIAVVVTIVLGSQVRLFPPIPEVLELPFQFAGVLGISAILLLQLWLFHERL
HHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVITQLRQTNAALEQERTGLQERVAQRTADLQQALAEVERQMAEQSRLLAENERQRELI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RGLSMPVLPVSQETLVMPLVGELDAERIAVAQATALQAIDRADARHLVLDITGMPFVDTT
HHCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
VAAGLMQLVQSARLLGATVTLVGVRPEVAQTIVALGIDLSEVTTAADLASALRRQRVTA
HHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SESTISILTLEQVRQLRRFFLWVAGIVGIVAIVATVSAAIWRTPTLIALMILDWVLVVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LLQAWAQTRSGQVRVALMTSFIALVLYGLFGAVILPNVASLMAFAPVLAIVAMLPFLSGV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLRRLLIVAWIAVVVTIVLGSQVRLFPPIPEVLELPFQFAGVLGISAILLLQLWLFHERL
HHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVITQLRQTNAALEQERTGLQERVAQRTADLQQALAEVERQMAEQSRLLAENERQRELI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RGLSMPVLPVSQETLVMPLVGELDAERIAVAQATALQAIDRADARHLVLDITGMPFVDTT
HHCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
VAAGLMQLVQSARLLGATVTLVGVRPEVAQTIVALGIDLSEVTTAADLASALRRQRVTA
HHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11157946 [H]