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The map label for this gene is rsbS [H]

Identifier: 222526126

GI number: 222526126

Start: 3567590

End: 3567976

Strand: Reverse

Name: rsbS [H]

Synonym: Chy400_2883

Alternate gene names: 222526126

Gene position: 3567976-3567590 (Counterclockwise)

Preceding gene: 222526127

Following gene: 222526125

Centisome position: 67.72

GC content: 49.35

Gene sequence:

>387_bases
TTGGATAATCTTCGCATTCCAATCTTGAAAATAGGCGACATTTTAATCGCCTCAATTCAGGTGGCGCTACACGATGCGTC
AGCAGTTCAATTTAAAGATGATCTGTTGCAGAAAATTCACGACACCCGTGCCCGTGGTGTGATTATTGATTTAACTGCTC
TTGATGTTGTCGATAGCTTTATCGGTCGCCTGATTGCCGACATTGCCGCAATGGCCGGCCTAATGGGTGCCCGTGTAGTC
CTTACCGGCTTGCAACCGGCCGTTGCTATCACCCTGGTTGAATTAGGACTTGAATTACCGCGTGTACTCACGGCTCTTAA
CCTCGAAAAGGGGTTGGCTATGATGCAGCGGATGACTGGTGAGGAGAGCGACGATGGCGCAGAGTAA

Upstream 100 bases:

>100_bases
ACCACTATTGGCCGGTGCAGTCATTGCCGTAATGCTAGGAGTTGTGTGATAATATTAGTCTGGTGGGGCAACGCTCACTG
AAGTTGTAGAGGAGCGCAGC

Downstream 100 bases:

>100_bases
GACTGCTGTCATTCGAAGCGACCTTGATATTGTCATCGCGCGCACCATGGCTCGCGATATGGCCAAGGCGCTCGGCTTCG
GGCCGATTGATCAGGCTCGT

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MDNLRIPILKIGDILIASIQVALHDASAVQFKDDLLQKIHDTRARGVIIDLTALDVVDSFIGRLIADIAAMAGLMGARVV
LTGLQPAVAITLVELGLELPRVLTALNLEKGLAMMQRMTGEESDDGAE

Sequences:

>Translated_128_residues
MDNLRIPILKIGDILIASIQVALHDASAVQFKDDLLQKIHDTRARGVIIDLTALDVVDSFIGRLIADIAAMAGLMGARVV
LTGLQPAVAITLVELGLELPRVLTALNLEKGLAMMQRMTGEESDDGAE
>Mature_128_residues
MDNLRIPILKIGDILIASIQVALHDASAVQFKDDLLQKIHDTRARGVIIDLTALDVVDSFIGRLIADIAAMAGLMGARVV
LTGLQPAVAITLVELGLELPRVLTALNLEKGLAMMQRMTGEESDDGAE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 13684; Mature: 13684

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLRIPILKIGDILIASIQVALHDASAVQFKDDLLQKIHDTRARGVIIDLTALDVVDSF
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHH
IGRLIADIAAMAGLMGARVVLTGLQPAVAITLVELGLELPRVLTALNLEKGLAMMQRMTG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EESDDGAE
CCCCCCCC
>Mature Secondary Structure
MDNLRIPILKIGDILIASIQVALHDASAVQFKDDLLQKIHDTRARGVIIDLTALDVVDSF
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHH
IGRLIADIAAMAGLMGARVVLTGLQPAVAITLVELGLELPRVLTALNLEKGLAMMQRMTG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EESDDGAE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]