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The map label for this gene is degU [H]

Identifier: 222526094

GI number: 222526094

Start: 3521676

End: 3522362

Strand: Reverse

Name: degU [H]

Synonym: Chy400_2851

Alternate gene names: 222526094

Gene position: 3522362-3521676 (Counterclockwise)

Preceding gene: 222526095

Following gene: 222526093

Centisome position: 66.85

GC content: 52.4

Gene sequence:

>687_bases
GTGAGTGTGACAACGCTGATAATTGTGCATACTGTCTCTCTCTTTCGAGATGGTTTGCGCCTTGCCCTGTCGTCAACGCC
TGGATTTTCAGTGGTTGGTGAAGCCAGCAATGGTCAACAGGCTATCCAGTTAGTGGATCAGGTTGATCCCGATCTGGTGC
TGATGGATACCGATTTGCCAGGTGTAAACGGGTTAGAGGTAGCGCGGGTTATCAAGCGAAGTCATCCTCACATTGCCATC
GTACTGTTTGGGCCGGTACAGAGTGGCGCGTTTGTGGTGAAGGCCATTCGTGCCGGCGTAGCGGCATGTGTGCCACCGAA
TATTGAATTTGCCGATCTGCTCGGCACGCTGCGTCAGGTGCGACGTGGCGAGTATCCGATCAACGATCTGGTATTGGCTT
CACCCGAAGTGGCTGCTACAGTTCTGGAGGCATTTCGGCAGATGGTCGGTGATGATGATATACAGACCATCTTTTCACCA
CTATCAGCGCGAGAGCTAGAAGTGCTGGAACTGGTAGCAGCCGGACATACCAATCGTGAGATCGCGGCCCGGCTTGATAT
CAGTAACCAGACTGTCAAGAATCACATTTCGTCGATTTTGCGCAAGCTGGCTGTGAATGATCGAACCCAGGCTGTGGTTT
ATGCAATGCGCCGGGGTTGGATCAAGGTTATGTTACCGAATGGGTAG

Upstream 100 bases:

>100_bases
TCGGTCAAGACGGGTACATTCATATTGTGATGCCAATGAGTATGCGATAGATGGTATCGGTGGCAGAGCCGACATCAACA
AATCGGTGGAGGAGTTACCC

Downstream 100 bases:

>100_bases
TGTACGACTCATTTGGTTGTTGATCAGCGCTGCATCCGGTCGCTGATCGGGTGGAGCATGAGGAGACGTTTGTGGGGCGT
TTCCGTGTTGTGCATCCTTG

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSVTTLIIVHTVSLFRDGLRLALSSTPGFSVVGEASNGQQAIQLVDQVDPDLVLMDTDLPGVNGLEVARVIKRSHPHIAI
VLFGPVQSGAFVVKAIRAGVAACVPPNIEFADLLGTLRQVRRGEYPINDLVLASPEVAATVLEAFRQMVGDDDIQTIFSP
LSARELEVLELVAAGHTNREIAARLDISNQTVKNHISSILRKLAVNDRTQAVVYAMRRGWIKVMLPNG

Sequences:

>Translated_228_residues
MSVTTLIIVHTVSLFRDGLRLALSSTPGFSVVGEASNGQQAIQLVDQVDPDLVLMDTDLPGVNGLEVARVIKRSHPHIAI
VLFGPVQSGAFVVKAIRAGVAACVPPNIEFADLLGTLRQVRRGEYPINDLVLASPEVAATVLEAFRQMVGDDDIQTIFSP
LSARELEVLELVAAGHTNREIAARLDISNQTVKNHISSILRKLAVNDRTQAVVYAMRRGWIKVMLPNG
>Mature_227_residues
SVTTLIIVHTVSLFRDGLRLALSSTPGFSVVGEASNGQQAIQLVDQVDPDLVLMDTDLPGVNGLEVARVIKRSHPHIAIV
LFGPVQSGAFVVKAIRAGVAACVPPNIEFADLLGTLRQVRRGEYPINDLVLASPEVAATVLEAFRQMVGDDDIQTIFSPL
SARELEVLELVAAGHTNREIAARLDISNQTVKNHISSILRKLAVNDRTQAVVYAMRRGWIKVMLPNG

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=215, Percent_Identity=33.0232558139535, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1787473, Length=210, Percent_Identity=34.7619047619048, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788222, Length=216, Percent_Identity=27.3148148148148, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1789937, Length=202, Percent_Identity=27.7227722772277, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786747, Length=217, Percent_Identity=23.963133640553, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788712, Length=189, Percent_Identity=23.2804232804233, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24646; Mature: 24515

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTTLIIVHTVSLFRDGLRLALSSTPGFSVVGEASNGQQAIQLVDQVDPDLVLMDTDLP
CCHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEECCCC
GVNGLEVARVIKRSHPHIAIVLFGPVQSGAFVVKAIRAGVAACVPPNIEFADLLGTLRQV
CCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCHHCCCCCCCHHHHHHHHHHHH
RRGEYPINDLVLASPEVAATVLEAFRQMVGDDDIQTIFSPLSARELEVLELVAAGHTNRE
HCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCE
IAARLDISNQTVKNHISSILRKLAVNDRTQAVVYAMRRGWIKVMLPNG
EEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure 
SVTTLIIVHTVSLFRDGLRLALSSTPGFSVVGEASNGQQAIQLVDQVDPDLVLMDTDLP
CHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEECCCC
GVNGLEVARVIKRSHPHIAIVLFGPVQSGAFVVKAIRAGVAACVPPNIEFADLLGTLRQV
CCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCHHCCCCCCCHHHHHHHHHHHH
RRGEYPINDLVLASPEVAATVLEAFRQMVGDDDIQTIFSPLSARELEVLELVAAGHTNRE
HCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCE
IAARLDISNQTVKNHISSILRKLAVNDRTQAVVYAMRRGWIKVMLPNG
EEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]