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The map label for this gene is gcvT [H]

Identifier: 222526066

GI number: 222526066

Start: 3484516

End: 3485505

Strand: Reverse

Name: gcvT [H]

Synonym: Chy400_2823

Alternate gene names: 222526066

Gene position: 3485505-3484516 (Counterclockwise)

Preceding gene: 222526067

Following gene: 222526065

Centisome position: 66.15

GC content: 57.68

Gene sequence:

>990_bases
ATGAATCAGGAAACACTGACAGCTTACGAGGCGGTGTATGGGTATGCTGCCGTGATCAACGAGTCTGATCGCGGACGGCT
CTGGATGCGTGGTCGCGACCGCGCAGCACTGCTACACCGGCTCTCGACGAACCATATCGAGCGATTACAGCCCGGTCAAG
GCACCCTGACCGCGCTCACCACGCCAATTGGGCGTATGATCGATCTGCTACGGGTATATGCCCTCCCTGACGCATTGTTG
CTTGAGACCGGCGATGGTCATGGACCGGCGATTTTGCGCCATTTGCGCAAGAATATCTTCTTCAACGATCAGGTGACGGT
CGCCGACGCGAGTGCCGAACTGGGTCAGATTGGCGTCTACGGGCCACAGGCTAGCCAGGTGATTCAGACGATTGGTTTGT
CGGTTGATCTGCCGCTACACAGTATCGCAACCGGTGACTGGAATGGACATCAGGTGCTGGTAGCACGGTGTGAACCGTTG
GGTGGCGATGGGTATACTCTCTATCCACCGGCAACGCAAACAACGACGCTGCTTACTGCGCTAACTGATGAAGGGGCCGT
TCCACTCGACAGTCATACGGCAGAAGTAGTACGCATCGAGCATGGCTATCCGCGCTTCAAACACGAGATCACACTGGATT
ATATTCCGCTCGAAGCCGATTTGTGGCGTGCGGTGAGTTTCCAGAAAGGGTGCTACGTTGGGCAAGAGATTATTGCCCGC
ATGGAGAGCCGGGGGCGGATCGCCAAGCTCTTGTGCGGCTTACGTCTGTCGGCTGCGCCCGAAGCGGTACCGGCAGCGGT
AACGGTGGATGGCAAAGAGGCTGGTACCCTGACCAGTGCTGCCTACTCACCACGCTACGGCTGGATCGGACTGGCCTATG
TGCGCCGTGCCTATGCCGAGAGTGGCACCATCGTGACCCTCGCTCAACAACCGGCAACCGTGTGTCGGCTACCATTCATT
AGTGGTACAACCCAGGACGATGCAGCATGA

Upstream 100 bases:

>100_bases
ACGGCATGCAATTACAGCTCAGAGAACGTCGAACAGTTTTGGGTGCAGCGTGATACAATATTTATGAACGATAAGCTTCT
GAGTAGATGATTGCTACGCT

Downstream 100 bases:

>100_bases
CTCGTACCGCACGTCGCCGACAACTGATAGGCGATCTGCAACGCCAGCGTGACGCATTGCGTCTGCAACAAGAGCGCGAC
CAGCAGATTCTGGCTGCGCT

Product: folate-binding protein YgfZ

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNQETLTAYEAVYGYAAVINESDRGRLWMRGRDRAALLHRLSTNHIERLQPGQGTLTALTTPIGRMIDLLRVYALPDALL
LETGDGHGPAILRHLRKNIFFNDQVTVADASAELGQIGVYGPQASQVIQTIGLSVDLPLHSIATGDWNGHQVLVARCEPL
GGDGYTLYPPATQTTTLLTALTDEGAVPLDSHTAEVVRIEHGYPRFKHEITLDYIPLEADLWRAVSFQKGCYVGQEIIAR
MESRGRIAKLLCGLRLSAAPEAVPAAVTVDGKEAGTLTSAAYSPRYGWIGLAYVRRAYAESGTIVTLAQQPATVCRLPFI
SGTTQDDAA

Sequences:

>Translated_329_residues
MNQETLTAYEAVYGYAAVINESDRGRLWMRGRDRAALLHRLSTNHIERLQPGQGTLTALTTPIGRMIDLLRVYALPDALL
LETGDGHGPAILRHLRKNIFFNDQVTVADASAELGQIGVYGPQASQVIQTIGLSVDLPLHSIATGDWNGHQVLVARCEPL
GGDGYTLYPPATQTTTLLTALTDEGAVPLDSHTAEVVRIEHGYPRFKHEITLDYIPLEADLWRAVSFQKGCYVGQEIIAR
MESRGRIAKLLCGLRLSAAPEAVPAAVTVDGKEAGTLTSAAYSPRYGWIGLAYVRRAYAESGTIVTLAQQPATVCRLPFI
SGTTQDDAA
>Mature_329_residues
MNQETLTAYEAVYGYAAVINESDRGRLWMRGRDRAALLHRLSTNHIERLQPGQGTLTALTTPIGRMIDLLRVYALPDALL
LETGDGHGPAILRHLRKNIFFNDQVTVADASAELGQIGVYGPQASQVIQTIGLSVDLPLHSIATGDWNGHQVLVARCEPL
GGDGYTLYPPATQTTTLLTALTDEGAVPLDSHTAEVVRIEHGYPRFKHEITLDYIPLEADLWRAVSFQKGCYVGQEIIAR
MESRGRIAKLLCGLRLSAAPEAVPAAVTVDGKEAGTLTSAAYSPRYGWIGLAYVRRAYAESGTIVTLAQQPATVCRLPFI
SGTTQDDAA

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0354

COG function: function code R; Predicted aminomethyltransferase related to GcvT

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=335, Percent_Identity=26.2686567164179, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI257796256, Length=318, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI44662838, Length=318, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI257796258, Length=309, Percent_Identity=26.2135922330097, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 35663; Mature: 35663

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQETLTAYEAVYGYAAVINESDRGRLWMRGRDRAALLHRLSTNHIERLQPGQGTLTALT
CCCHHHHHHHHHHHEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEHH
TPIGRMIDLLRVYALPDALLLETGDGHGPAILRHLRKNIFFNDQVTVADASAELGQIGVY
CCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCEECCCEEEEECCCCCCCEECC
GPQASQVIQTIGLSVDLPLHSIATGDWNGHQVLVARCEPLGGDGYTLYPPATQTTTLLTA
CCCHHHHHHHHCCEEECCHHHEECCCCCCCEEEEEECCCCCCCCEEECCCCCCHHEEEEE
LTDEGAVPLDSHTAEVVRIEHGYPRFKHEITLDYIPLEADLWRAVSFQKGCYVGQEIIAR
ECCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHCCCHHHHHHHHH
MESRGRIAKLLCGLRLSAAPEAVPAAVTVDGKEAGTLTSAAYSPRYGWIGLAYVRRAYAE
HHHCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHC
SGTIVTLAQQPATVCRLPFISGTTQDDAA
CCCEEEEECCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MNQETLTAYEAVYGYAAVINESDRGRLWMRGRDRAALLHRLSTNHIERLQPGQGTLTALT
CCCHHHHHHHHHHHEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEHH
TPIGRMIDLLRVYALPDALLLETGDGHGPAILRHLRKNIFFNDQVTVADASAELGQIGVY
CCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCEECCCEEEEECCCCCCCEECC
GPQASQVIQTIGLSVDLPLHSIATGDWNGHQVLVARCEPLGGDGYTLYPPATQTTTLLTA
CCCHHHHHHHHCCEEECCHHHEECCCCCCCEEEEEECCCCCCCCEEECCCCCCHHEEEEE
LTDEGAVPLDSHTAEVVRIEHGYPRFKHEITLDYIPLEADLWRAVSFQKGCYVGQEIIAR
ECCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHCCCHHHHHHHHH
MESRGRIAKLLCGLRLSAAPEAVPAAVTVDGKEAGTLTSAAYSPRYGWIGLAYVRRAYAE
HHHCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHC
SGTIVTLAQQPATVCRLPFISGTTQDDAA
CCCEEEEECCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA