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The map label for this gene is aroC

Identifier: 222525964

GI number: 222525964

Start: 3355808

End: 3356902

Strand: Reverse

Name: aroC

Synonym: Chy400_2720

Alternate gene names: 222525964

Gene position: 3356902-3355808 (Counterclockwise)

Preceding gene: 222525965

Following gene: 222525963

Centisome position: 63.71

GC content: 59.45

Gene sequence:

>1095_bases
ATGCCAGGCAATACATTTGGTCATGTCTTTCGCGTAACTACCTGGGGCGAGTCACACGGCCCGGCGGTTGGTTGCACTGT
CGATGGCTGCCCGGCCGGTCTACCCCTCGACGTTGCCGATATTCAACGTGAACTGGATCGCCGTCGCGTCGGCCAGAGTC
GGGTCAGCTCACAGCGCCGGGAAGCCGATGAGGTGCAGATACTTTCTGGCGTCTTCGAGGGGCGTACTACCGGTACCCCG
ATCACGATGCTGGTATACAATACAGACGCTAAATCACACCATTACGAGAACATCAAAGATCGCTACCGTCCCGGCCACGC
CGATTACACCTGGGATGCCAAGTACGGGTTTCGCGACTGGCGTGGCGGCGGACGCTCATCGGCACGCGAGACCATCGGGC
GAGTCGCGGCAGGAGCTGTCGCCCGCCGTCTGCTGGCAACGTTTGGTATCACACTTGTTGGCTACACGCTGCAACTGGCC
GATCTGCGGGCTGAAGTCTTCGACGAAGCAGAGATCGAGCGCAATATTATGCGCTGTCCCGATGCCCGTGTCGCAGCGCT
GATGGTCGAGCGGGTTGATCAAGCCCGACGAGAACTCGACTCATTGGGGGGCATCGTTGAAGTGCGCGCACGTGGTGTAC
CGCCCGGTCTCGGAGAACCGGTATTTGACAAATTGCAGGCCGATATTGGCAAGGCGATGTTCTCTATCCCGGCCATTAAA
GGGGTCGAAATTGGTGAAGGGTTCGGGGTCGCAATGCTACGCGGCTCGCAGAACAACGATCCGTTCATTCGCCGGGATGA
TGGTACCATCGGAACTGTATCCAATCATCACGGCGGTATTCTAGGTGGCATCTCAACCGGCGAAGAGATCGTTGTGCGAC
TGGCCGCCAAACCACCGGCCAGCATCGCCCAACCGCAGCAGACGGTTGATCGCGACGGAAATCCGGTCACGATTGAAGTG
CATGGACGGCATGATCCAACCGTCCTGCCCCGGCTGGTGCCGGTAGCCGAAGCGATGCTGGCGTTAGTCCTGGCCGATCA
CCTGCTCCGTCAACGACTTGCCCGCGTGACGTGGGAGGATAGGAGTGATGACTGA

Upstream 100 bases:

>100_bases
TCAAAGCAGTGTACGATCGAGTCTGGACGGAATGGAAAGCCGGCTCGTGGGGAAAAGAGATTATGCGTCGTGCTTGAATA
TCATCAATCATGGAGATGTT

Downstream 100 bases:

>100_bases
TCAGGAGGAAACCCCGAAGGTAAGACGCTGGTTACCACTGCTGGCATTGCTGGCCGGCCTGTGCTGGGCACTGGTTATCA
GCGTGATCCTCAGGGTCGAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MPGNTFGHVFRVTTWGESHGPAVGCTVDGCPAGLPLDVADIQRELDRRRVGQSRVSSQRREADEVQILSGVFEGRTTGTP
ITMLVYNTDAKSHHYENIKDRYRPGHADYTWDAKYGFRDWRGGGRSSARETIGRVAAGAVARRLLATFGITLVGYTLQLA
DLRAEVFDEAEIERNIMRCPDARVAALMVERVDQARRELDSLGGIVEVRARGVPPGLGEPVFDKLQADIGKAMFSIPAIK
GVEIGEGFGVAMLRGSQNNDPFIRRDDGTIGTVSNHHGGILGGISTGEEIVVRLAAKPPASIAQPQQTVDRDGNPVTIEV
HGRHDPTVLPRLVPVAEAMLALVLADHLLRQRLARVTWEDRSDD

Sequences:

>Translated_364_residues
MPGNTFGHVFRVTTWGESHGPAVGCTVDGCPAGLPLDVADIQRELDRRRVGQSRVSSQRREADEVQILSGVFEGRTTGTP
ITMLVYNTDAKSHHYENIKDRYRPGHADYTWDAKYGFRDWRGGGRSSARETIGRVAAGAVARRLLATFGITLVGYTLQLA
DLRAEVFDEAEIERNIMRCPDARVAALMVERVDQARRELDSLGGIVEVRARGVPPGLGEPVFDKLQADIGKAMFSIPAIK
GVEIGEGFGVAMLRGSQNNDPFIRRDDGTIGTVSNHHGGILGGISTGEEIVVRLAAKPPASIAQPQQTVDRDGNPVTIEV
HGRHDPTVLPRLVPVAEAMLALVLADHLLRQRLARVTWEDRSDD
>Mature_363_residues
PGNTFGHVFRVTTWGESHGPAVGCTVDGCPAGLPLDVADIQRELDRRRVGQSRVSSQRREADEVQILSGVFEGRTTGTPI
TMLVYNTDAKSHHYENIKDRYRPGHADYTWDAKYGFRDWRGGGRSSARETIGRVAAGAVARRLLATFGITLVGYTLQLAD
LRAEVFDEAEIERNIMRCPDARVAALMVERVDQARRELDSLGGIVEVRARGVPPGLGEPVFDKLQADIGKAMFSIPAIKG
VEIGEGFGVAMLRGSQNNDPFIRRDDGTIGTVSNHHGGILGGISTGEEIVVRLAAKPPASIAQPQQTVDRDGNPVTIEVH
GRHDPTVLPRLVPVAEAMLALVLADHLLRQRLARVTWEDRSDD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=353, Percent_Identity=56.657223796034, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6321290, Length=365, Percent_Identity=46.8493150684932, Blast_Score=326, Evalue=4e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_CHLAA (A9WI34)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636114.1
- ProteinModelPortal:   A9WI34
- SMR:   A9WI34
- GeneID:   5826987
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_2519
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39706; Mature: 39575

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGNTFGHVFRVTTWGESHGPAVGCTVDGCPAGLPLDVADIQRELDRRRVGQSRVSSQRR
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EADEVQILSGVFEGRTTGTPITMLVYNTDAKSHHYENIKDRYRPGHADYTWDAKYGFRDW
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHC
RGGGRSSARETIGRVAAGAVARRLLATFGITLVGYTLQLADLRAEVFDEAEIERNIMRCP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DARVAALMVERVDQARRELDSLGGIVEVRARGVPPGLGEPVFDKLQADIGKAMFSIPAIK
CHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
GVEIGEGFGVAMLRGSQNNDPFIRRDDGTIGTVSNHHGGILGGISTGEEIVVRLAAKPPA
CEEECCCCCEEEEECCCCCCCEEEECCCCEECCCCCCCCEEECCCCCHHHEEEECCCCCH
SIAQPQQTVDRDGNPVTIEVHGRHDPTVLPRLVPVAEAMLALVLADHLLRQRLARVTWED
HHCCCHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RSDD
CCCC
>Mature Secondary Structure 
PGNTFGHVFRVTTWGESHGPAVGCTVDGCPAGLPLDVADIQRELDRRRVGQSRVSSQRR
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EADEVQILSGVFEGRTTGTPITMLVYNTDAKSHHYENIKDRYRPGHADYTWDAKYGFRDW
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHC
RGGGRSSARETIGRVAAGAVARRLLATFGITLVGYTLQLADLRAEVFDEAEIERNIMRCP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DARVAALMVERVDQARRELDSLGGIVEVRARGVPPGLGEPVFDKLQADIGKAMFSIPAIK
CHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
GVEIGEGFGVAMLRGSQNNDPFIRRDDGTIGTVSNHHGGILGGISTGEEIVVRLAAKPPA
CEEECCCCCEEEEECCCCCCCEEEECCCCEECCCCCCCCEEECCCCCHHHEEEECCCCCH
SIAQPQQTVDRDGNPVTIEVHGRHDPTVLPRLVPVAEAMLALVLADHLLRQRLARVTWED
HHCCCHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RSDD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA