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The map label for this gene is cya [H]

Identifier: 222525677

GI number: 222525677

Start: 3063014

End: 3064327

Strand: Reverse

Name: cya [H]

Synonym: Chy400_2428

Alternate gene names: 222525677

Gene position: 3064327-3063014 (Counterclockwise)

Preceding gene: 222525678

Following gene: 222525676

Centisome position: 58.16

GC content: 46.35

Gene sequence:

>1314_bases
ATGCACTACTCACTCAGACAACCGACGAGTGTAAATGATACAGCCTCTATAACTGAAGACCAGGGGCGAGGTTCGCCGGG
TCTACGATTCGTTTCTGAATGCGCCACGAATTCACTCTTTTTCCCCTTAGCTGCGGTTGGATGCGAAGCAGTTACGGTAT
CACCCGGTGTCTATTTTTCTTCCGCCCTACCCTATATTCTGATCACAGCCGGCCTGTTACAGACCTGCTACTTGAGCATC
TACGCCAACAACTCGTCATGGCATCGCCTAACAGGGAACCTGATTGGCCCAATCCTCTACAGTATCGGTGGTTATATTTA
CGAAGGCCCTCATTTCTGGTTTCATCTCTTACATTTTGCGTATTGGGGTTTTGCCCTCACGATTGCTATACTCCAATTTC
TACGCGCCCAAATTGCTCTGACAGCCATCAATCCTATCGTGATCATTAGTGAAAATATCATTCGCACCAGCATCATCCTC
TTCTTGTTTTACACTTTTCAAGAAGATCAACCGTTCAATCAGCACCTATCCATTCAGCAATTTTTCAACAACCCTGATCA
TCAAATAATCACATTTCTCATCCTGTTGCTCGGCACCATTGCCGGGCTGACCCATGCGTACAGTGAATGGCACTTACGTC
TGCTCACTAAAACAATCAGACAATTCAACAGGTTCGCTGAATGGTTGCTCGGTCGTAAACTACTACATCTCTCGCTAACA
AATCCAGATCAATTAACCCTACAACGTCGTGAACGCAGTATATTGTTCATGGATATTCGCGGTTTTACGACATGGAGTGA
ACACAGAACGCCCGAAGAAGTTGTGCAATTACTCAATTCGTATTATCAGATTATTGAACAGGTATTTTCTGGCTATCAAG
TTATCAAGTACAAACTATCAGCCGATGAGGCAATGGCCATTTTCCCCGACCCGACGACAGCCATTCAGGCTGCCATTATG
ATTCGGTCACATATTCAACCGTTGCTCGACCACGAGCAGTTGGGTGTTGGAATCGGTATCCATCACGGCCCCGTCGTTGA
AGGACTGTTAGGTAGCCGTGGGGTCAGGTTTTATGATGTGATCGGAGATACGGTTAATACTGCGAAACGCCTGGAAAGCG
TCGCTCGCAAAGGTGAAATCCTGGTCTCTAGCCGTGCATATCAAGCCATTAACGAAGGATGTTATCGAATTACGCCAGAT
ATTATTACCGTCAAAGGAAAGAAAAACCCCTTACAGGTCTATGTATTCTCCGAAACCACCCATCTCACCAATGCCGAACC
ATCAGCCTGCCAGGCAGAGCCTGAACATGAATGA

Upstream 100 bases:

>100_bases
CGCTTCAGCATGTCTTCAGAATCTTTTTTTAAGATGTTGATACAACCCTTATGGGTGTAGATATGAATCAAACCACTGTA
CTAACGAACAGGAATACCAT

Downstream 100 bases:

>100_bases
TATTCGCTAGAACCTGTTATGGACTTTTGAGTTCTGATCGTATAACATTGAGGTATGACACGAACAACCATCCGAGTGAT
AGTTCTGGCGCGATGTGGAC

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MHYSLRQPTSVNDTASITEDQGRGSPGLRFVSECATNSLFFPLAAVGCEAVTVSPGVYFSSALPYILITAGLLQTCYLSI
YANNSSWHRLTGNLIGPILYSIGGYIYEGPHFWFHLLHFAYWGFALTIAILQFLRAQIALTAINPIVIISENIIRTSIIL
FLFYTFQEDQPFNQHLSIQQFFNNPDHQIITFLILLLGTIAGLTHAYSEWHLRLLTKTIRQFNRFAEWLLGRKLLHLSLT
NPDQLTLQRRERSILFMDIRGFTTWSEHRTPEEVVQLLNSYYQIIEQVFSGYQVIKYKLSADEAMAIFPDPTTAIQAAIM
IRSHIQPLLDHEQLGVGIGIHHGPVVEGLLGSRGVRFYDVIGDTVNTAKRLESVARKGEILVSSRAYQAINEGCYRITPD
IITVKGKKNPLQVYVFSETTHLTNAEPSACQAEPEHE

Sequences:

>Translated_437_residues
MHYSLRQPTSVNDTASITEDQGRGSPGLRFVSECATNSLFFPLAAVGCEAVTVSPGVYFSSALPYILITAGLLQTCYLSI
YANNSSWHRLTGNLIGPILYSIGGYIYEGPHFWFHLLHFAYWGFALTIAILQFLRAQIALTAINPIVIISENIIRTSIIL
FLFYTFQEDQPFNQHLSIQQFFNNPDHQIITFLILLLGTIAGLTHAYSEWHLRLLTKTIRQFNRFAEWLLGRKLLHLSLT
NPDQLTLQRRERSILFMDIRGFTTWSEHRTPEEVVQLLNSYYQIIEQVFSGYQVIKYKLSADEAMAIFPDPTTAIQAAIM
IRSHIQPLLDHEQLGVGIGIHHGPVVEGLLGSRGVRFYDVIGDTVNTAKRLESVARKGEILVSSRAYQAINEGCYRITPD
IITVKGKKNPLQVYVFSETTHLTNAEPSACQAEPEHE
>Mature_437_residues
MHYSLRQPTSVNDTASITEDQGRGSPGLRFVSECATNSLFFPLAAVGCEAVTVSPGVYFSSALPYILITAGLLQTCYLSI
YANNSSWHRLTGNLIGPILYSIGGYIYEGPHFWFHLLHFAYWGFALTIAILQFLRAQIALTAINPIVIISENIIRTSIIL
FLFYTFQEDQPFNQHLSIQQFFNNPDHQIITFLILLLGTIAGLTHAYSEWHLRLLTKTIRQFNRFAEWLLGRKLLHLSLT
NPDQLTLQRRERSILFMDIRGFTTWSEHRTPEEVVQLLNSYYQIIEQVFSGYQVIKYKLSADEAMAIFPDPTTAIQAAIM
IRSHIQPLLDHEQLGVGIGIHHGPVVEGLLGSRGVRFYDVIGDTVNTAKRLESVARKGEILVSSRAYQAINEGCYRITPD
IITVKGKKNPLQVYVFSETTHLTNAEPSACQAEPEHE

Specific function: May function as a membrane-localized receptor protein [H]

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Homo sapiens, GI4580422, Length=180, Percent_Identity=34.4444444444444, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI167830411, Length=247, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71989822, Length=147, Percent_Identity=37.4149659863946, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71989805, Length=147, Percent_Identity=37.4149659863946, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534659, Length=171, Percent_Identity=35.0877192982456, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561804, Length=170, Percent_Identity=30, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17508769, Length=132, Percent_Identity=38.6363636363636, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193206632, Length=180, Percent_Identity=29.4444444444444, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17534665, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115535133, Length=151, Percent_Identity=33.7748344370861, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71995305, Length=146, Percent_Identity=34.2465753424658, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17568383, Length=157, Percent_Identity=32.484076433121, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI161078020, Length=204, Percent_Identity=31.3725490196078, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281366459, Length=172, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281366457, Length=172, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281366455, Length=172, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI56292422, Length=172, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI56292424, Length=172, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666940, Length=172, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574512, Length=171, Percent_Identity=33.9181286549708, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI161076872, Length=171, Percent_Identity=33.9181286549708, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI85725044, Length=237, Percent_Identity=29.535864978903, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221330468, Length=173, Percent_Identity=30.635838150289, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221330470, Length=173, Percent_Identity=30.635838150289, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116008008, Length=211, Percent_Identity=27.9620853080569, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI62484477, Length=211, Percent_Identity=27.9620853080569, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI62484298, Length=211, Percent_Identity=27.9620853080569, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24647268, Length=183, Percent_Identity=31.6939890710383, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24663843, Length=180, Percent_Identity=31.6666666666667, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24663839, Length=180, Percent_Identity=31.6666666666667, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24583976, Length=222, Percent_Identity=25.2252252252252, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583978, Length=186, Percent_Identity=29.5698924731183, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 49348; Mature: 49348

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYSLRQPTSVNDTASITEDQGRGSPGLRFVSECATNSLFFPLAAVGCEAVTVSPGVYFS
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEECCCCHHH
SALPYILITAGLLQTCYLSIYANNSSWHRLTGNLIGPILYSIGGYIYEGPHFWFHLLHFA
HCCHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHH
YWGFALTIAILQFLRAQIALTAINPIVIISENIIRTSIILFLFYTFQEDQPFNQHLSIQQ
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
FFNNPDHQIITFLILLLGTIAGLTHAYSEWHLRLLTKTIRQFNRFAEWLLGRKLLHLSLT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
NPDQLTLQRRERSILFMDIRGFTTWSEHRTPEEVVQLLNSYYQIIEQVFSGYQVIKYKLS
CCHHHHHHHHCCCEEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
ADEAMAIFPDPTTAIQAAIMIRSHIQPLLDHEQLGVGIGIHHGPVVEGLLGSRGVRFYDV
CCCEEEECCCCHHHHHHHHHHHHHHHHHHCHHHCCEEECCCCCHHHHHHHCCCCCEEEEH
IGDTVNTAKRLESVARKGEILVSSRAYQAINEGCYRITPDIITVKGKKNPLQVYVFSETT
HCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCEEECCCEEEEECCCCCEEEEEEECCC
HLTNAEPSACQAEPEHE
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHYSLRQPTSVNDTASITEDQGRGSPGLRFVSECATNSLFFPLAAVGCEAVTVSPGVYFS
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEECCCCHHH
SALPYILITAGLLQTCYLSIYANNSSWHRLTGNLIGPILYSIGGYIYEGPHFWFHLLHFA
HCCHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHH
YWGFALTIAILQFLRAQIALTAINPIVIISENIIRTSIILFLFYTFQEDQPFNQHLSIQQ
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
FFNNPDHQIITFLILLLGTIAGLTHAYSEWHLRLLTKTIRQFNRFAEWLLGRKLLHLSLT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
NPDQLTLQRRERSILFMDIRGFTTWSEHRTPEEVVQLLNSYYQIIEQVFSGYQVIKYKLS
CCHHHHHHHHCCCEEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
ADEAMAIFPDPTTAIQAAIMIRSHIQPLLDHEQLGVGIGIHHGPVVEGLLGSRGVRFYDV
CCCEEEECCCCHHHHHHHHHHHHHHHHHHCHHHCCEEECCCCCHHHHHHHCCCCCEEEEH
IGDTVNTAKRLESVARKGEILVSSRAYQAINEGCYRITPDIITVKGKKNPLQVYVFSETT
HCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCEEECCCEEEEECCCCCEEEEEEECCC
HLTNAEPSACQAEPEHE
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7601856 [H]