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The map label for this gene is ybeX [C]

Identifier: 222525615

GI number: 222525615

Start: 2986786

End: 2988129

Strand: Reverse

Name: ybeX [C]

Synonym: Chy400_2366

Alternate gene names: 222525615

Gene position: 2988129-2986786 (Counterclockwise)

Preceding gene: 222525616

Following gene: 222525614

Centisome position: 56.71

GC content: 55.43

Gene sequence:

>1344_bases
TTGGAAGACCCTGGCCCTAGTTCGCTCGTTATCGGTATTGGCCTGTGTCTAATTGCGCTGGGTATTACCTCAGCCGCCGA
CACAGCCCTGATAACGGTGAGTCGTCCCCGGCTGAGCAGCCTGCTCGCTTCGGCTGGTCTCGGTACACGCCGCTTTGCGG
CCCATTTTCTCGATGAACCATACCGCATCAAATCTGCCATTATCTTTCTCAACGCAACCCTGACGATTACCGTCACGGCC
CTGACTATCCAGCTCGTTGCGCCGTATGGGCTGTCAATGATTATCGGCAGTCTGGCGGGATTGCTGTTTGCCATTTTACT
CCTGAGCGAAGTTGTCGCCAAAGCCCTTGCTCTGCGGAGTCCCGACACGACGATCCTGATCCTCGCCCGGCCACTGGTCG
CCATTGCAATGGTGTTATGGCCGGTGATGGCAGTGATCAATATCATTACGCGCCCCATTTTTACCCTCTTAAGCGGCCAA
CCGGCTCCTCCCACGCCACTGGTAACCGAAGAGGAGTTGCGGCTGATGATGAGTGCCGGCGAAAAGGCCGGTTGGATCGA
GCATGAAGAGCGCGAGATGATTGAGGGGGTCATGGATTTCGGTGATACCCTGGTGCGCGAGATTATGATTCCGCGGGTCG
ATGTGGTAGCACTGGAAGTCAATAGCCCGCTGAAACGTGCGCTTGATGTGGCGATTACGCGCGGCCATTCGCGGATTCCT
GTGTATGAAGAGACCATTGATAACGTTGTCGGTATTCTCTACGTCAAAGACCTGATCCCCGTCTTGCGCGATGGTAAGCA
CGATACACCGTTGCGCGATCTGCTCCGACCGGCATACTTTGTGCCGGTAACGATGAAGGTCGCTGCCCTGTTAGAAGATT
TGCAGCGGCGGCGAGTGCATATGGCCATTGTGGTTGATGAATACGGTGGTACTGCCGGTATTGTAACGCTCGAAGATTTG
ATTGAACAGATTGTTGGTGAAATTCGTGATGAGTACGATACCGAAGAGCCGGCCATCGTTGAGGTTGGGCCGAACGAGCT
GATCGTTGATGCCCGGGTGCCGATTGATGATGTCGCCGGGTTATTAGAGGTCGAATTTCCCGAAACGACTGCGGATCGCA
TCGGTGGTCTGGTCTACGAGCAATTGGGGCGTATCCCGCGTGAAGGCGATCAGGTGGTCTGCAACGATGTGACCATCACC
GTGCTCTCGATCAAGGGGATTCGTGCCGAACGATTACGGATTGTCCGGCAGGCACCGGCTGAAATAACAGCGGCAGCGCC
GGTGGATGCCGAAAAACCGCTGTTGCCGCTTCCTAAAGAATTGCATGGATCCAGTGGCCCTTGA

Upstream 100 bases:

>100_bases
CCTGATGACGCGGTCGTTGTGCGCCCGAAGGGAGTATCAATTCGGGCGCCATTGTTGAGTGAAGCGCGCCACTCTGTTCC
GCGAAAGGAGGATGATTCTC

Downstream 100 bases:

>100_bases
GCAATTGATCGCCGCGGCATTGCATGCCCGGCAGCGTGCATATGCACCCTATTCACACTTCGCGGTTGGTGCCGCCGTCC
TAACCGATGATGGCCGTATC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MEDPGPSSLVIGIGLCLIALGITSAADTALITVSRPRLSSLLASAGLGTRRFAAHFLDEPYRIKSAIIFLNATLTITVTA
LTIQLVAPYGLSMIIGSLAGLLFAILLLSEVVAKALALRSPDTTILILARPLVAIAMVLWPVMAVINIITRPIFTLLSGQ
PAPPTPLVTEEELRLMMSAGEKAGWIEHEEREMIEGVMDFGDTLVREIMIPRVDVVALEVNSPLKRALDVAITRGHSRIP
VYEETIDNVVGILYVKDLIPVLRDGKHDTPLRDLLRPAYFVPVTMKVAALLEDLQRRRVHMAIVVDEYGGTAGIVTLEDL
IEQIVGEIRDEYDTEEPAIVEVGPNELIVDARVPIDDVAGLLEVEFPETTADRIGGLVYEQLGRIPREGDQVVCNDVTIT
VLSIKGIRAERLRIVRQAPAEITAAAPVDAEKPLLPLPKELHGSSGP

Sequences:

>Translated_447_residues
MEDPGPSSLVIGIGLCLIALGITSAADTALITVSRPRLSSLLASAGLGTRRFAAHFLDEPYRIKSAIIFLNATLTITVTA
LTIQLVAPYGLSMIIGSLAGLLFAILLLSEVVAKALALRSPDTTILILARPLVAIAMVLWPVMAVINIITRPIFTLLSGQ
PAPPTPLVTEEELRLMMSAGEKAGWIEHEEREMIEGVMDFGDTLVREIMIPRVDVVALEVNSPLKRALDVAITRGHSRIP
VYEETIDNVVGILYVKDLIPVLRDGKHDTPLRDLLRPAYFVPVTMKVAALLEDLQRRRVHMAIVVDEYGGTAGIVTLEDL
IEQIVGEIRDEYDTEEPAIVEVGPNELIVDARVPIDDVAGLLEVEFPETTADRIGGLVYEQLGRIPREGDQVVCNDVTIT
VLSIKGIRAERLRIVRQAPAEITAAAPVDAEKPLLPLPKELHGSSGP
>Mature_447_residues
MEDPGPSSLVIGIGLCLIALGITSAADTALITVSRPRLSSLLASAGLGTRRFAAHFLDEPYRIKSAIIFLNATLTITVTA
LTIQLVAPYGLSMIIGSLAGLLFAILLLSEVVAKALALRSPDTTILILARPLVAIAMVLWPVMAVINIITRPIFTLLSGQ
PAPPTPLVTEEELRLMMSAGEKAGWIEHEEREMIEGVMDFGDTLVREIMIPRVDVVALEVNSPLKRALDVAITRGHSRIP
VYEETIDNVVGILYVKDLIPVLRDGKHDTPLRDLLRPAYFVPVTMKVAALLEDLQRRRVHMAIVVDEYGGTAGIVTLEDL
IEQIVGEIRDEYDTEEPAIVEVGPNELIVDARVPIDDVAGLLEVEFPETTADRIGGLVYEQLGRIPREGDQVVCNDVTIT
VLSIKGIRAERLRIVRQAPAEITAAAPVDAEKPLLPLPKELHGSSGP

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=278, Percent_Identity=29.4964028776978, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI94681046, Length=304, Percent_Identity=28.6184210526316, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40068049, Length=159, Percent_Identity=35.8490566037736, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40068055, Length=346, Percent_Identity=26.5895953757225, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI40068053, Length=346, Percent_Identity=26.5895953757225, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786879, Length=286, Percent_Identity=36.013986013986, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI145693175, Length=412, Percent_Identity=25.4854368932039, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790664, Length=355, Percent_Identity=27.887323943662, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082033, Length=271, Percent_Identity=27.6752767527675, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788119, Length=240, Percent_Identity=31.6666666666667, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71980512, Length=306, Percent_Identity=29.0849673202614, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48460; Mature: 48460

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDPGPSSLVIGIGLCLIALGITSAADTALITVSRPRLSSLLASAGLGTRRFAAHFLDEP
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHCCCC
YRIKSAIIFLNATLTITVTALTIQLVAPYGLSMIIGSLAGLLFAILLLSEVVAKALALRS
CEEEEEEEEEEEEEEEEEEEHEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDTTILILARPLVAIAMVLWPVMAVINIITRPIFTLLSGQPAPPTPLVTEEELRLMMSAG
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCC
EKAGWIEHEEREMIEGVMDFGDTLVREIMIPRVDVVALEVNSPLKRALDVAITRGHSRIP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCCCC
VYEETIDNVVGILYVKDLIPVLRDGKHDTPLRDLLRPAYFVPVTMKVAALLEDLQRRRVH
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHHHCCEE
MAIVVDEYGGTAGIVTLEDLIEQIVGEIRDEYDTEEPAIVEVGPNELIVDARVPIDDVAG
EEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCHHHHCC
LLEVEFPETTADRIGGLVYEQLGRIPREGDQVVCNDVTITVLSIKGIRAERLRIVRQAPA
CEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEEEECCCHHHHHHHHHHCCC
EITAAAPVDAEKPLLPLPKELHGSSGP
CEEECCCCCCCCCCCCCCHHHCCCCCC
>Mature Secondary Structure
MEDPGPSSLVIGIGLCLIALGITSAADTALITVSRPRLSSLLASAGLGTRRFAAHFLDEP
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHCCCC
YRIKSAIIFLNATLTITVTALTIQLVAPYGLSMIIGSLAGLLFAILLLSEVVAKALALRS
CEEEEEEEEEEEEEEEEEEEHEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDTTILILARPLVAIAMVLWPVMAVINIITRPIFTLLSGQPAPPTPLVTEEELRLMMSAG
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCC
EKAGWIEHEEREMIEGVMDFGDTLVREIMIPRVDVVALEVNSPLKRALDVAITRGHSRIP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCCCC
VYEETIDNVVGILYVKDLIPVLRDGKHDTPLRDLLRPAYFVPVTMKVAALLEDLQRRRVH
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHHHCCEE
MAIVVDEYGGTAGIVTLEDLIEQIVGEIRDEYDTEEPAIVEVGPNELIVDARVPIDDVAG
EEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCHHHHCC
LLEVEFPETTADRIGGLVYEQLGRIPREGDQVVCNDVTITVLSIKGIRAERLRIVRQAPA
CEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEEEECCCHHHHHHHHHHCCC
EITAAAPVDAEKPLLPLPKELHGSSGP
CEEECCCCCCCCCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]