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The map label for this gene is pgi [H]

Identifier: 222525598

GI number: 222525598

Start: 2970615

End: 2972021

Strand: Reverse

Name: pgi [H]

Synonym: Chy400_2348

Alternate gene names: 222525598

Gene position: 2972021-2970615 (Counterclockwise)

Preceding gene: 222525600

Following gene: 222525597

Centisome position: 56.41

GC content: 59.42

Gene sequence:

>1407_bases
ATGCGCTATGAGGATGCCGCGTGGCGGGAGAAGCAACGCATTCGGCTCGATGTGAATAATGTGTTTGGAACGCATGGTTT
GACCCCGGCTGAACTTGAAGCAGAAGCTCCACGCGCCGCCGCAGCGATTGCTGCCGTCCAGGAACGACGGGCCGATCTCG
GCTGGCCGTTGTTGCCGGATCAGGACGTGACGCCGTTTGAGCAGTTTGCCGCTGCCCATCGTGATCGGATTGATACCTTT
GTCGTGCTGGGCATTGGTGGTTCGGCGTTGGGGAACATCGCAGTGCAGACGGCAATCAATGGGCCGTTTTATAACCTGCT
ACCACGCGAGCAACGTGGCTGGCCGCGGCTGCTGGTACTCGATAATTCGGACCCGGAATTGAATGCAGGTGCGCTACGGA
TGCTCGATCTCCGGCGGACGATGTTCAACGTCATTAGCAAGAGCGGCACTACCGCCGAGACGATGGCTTCATTTCTTTAC
TTTCGCCAGGCGCTGGTCGAGGCAGTCGGCGAAGACCGGCTCGGTGACCATATCGTGTTGACGACCGATCCCAACAGTGG
TTTTCTGCGCCAGATTGGGCAGCGTGAGGGCTGGACGATGTTCGATCTCCCGCCAAAGGTCGGTGGCCGCTTCTCGGTAT
TGACCTCGGTCGGGTTGTTGTCGGCGGCGATGACGGGGGTGAATATTCGTGAGCTACTGGCCGGTGCCGCTTACGGTCGC
GAACTGGCCGCCAACCCCGATCCGTTGCGGAACCCGGCAGCCCTTGGCGCACTCATCAACTACCTCTGCTTCCGCAAAGG
CAAGCCGATTGTGGTGATGATGCCGTATGCGAACCGGCTCCGTGATGTCGCCGACTGGTTTGCCCAATTGTGGGCCGAGA
GTCTGGGCAAGGCGGTAGATCGCCAGGGCAAGCCGGCGCGGGTCGGGCAGACACCGGTCAAGGCTTTGGGCGCAACCGAT
CAGCATTCGCAGGTTCAACTCTATATGGAAGGGCCGTATGACAAGCTGATCAATTTCATCGCCGTTGAACAGTACGCCGA
GACGGCCCCCATTCCAACGGCATACGCCGATCTGGAAGGCGTGAGCTATCTGGGTGGGCATACGATGGCCGAGCTGATCC
AGGCCGAACAACAGGCCACTGCGATTGCGTTGAGTGAAGCCGGTCAACCAAACATCACGCATATCTTCCCGGAGATCAAT
GCCTTTACGCTCGGTCAGTTCTTTATGCTGATGGAGATGCAGACGGCGATTGCCGGTGAGCTGTACGACATCAACGCATT
CGATCAACCGGGGGTTGAGGCCGGGAAGATCAACACGTATGCGCTGTTGGGCCGGCGTGGGTTTGAGGAGCGGCGAGCAG
CGATTGCTGCCCGTGCGCAGGCGCTTGATTCGCGGTGGGTCGTGTAA

Upstream 100 bases:

>100_bases
AGCACTGATAAGCTCATTGTGATCACATGCAAGTGACGGCACTGCTTCACTTCTGCGTTTGCGGAAGTTGCGTACACACC
AATTAGTGAAGGAGTTGAGT

Downstream 100 bases:

>100_bases
ACATTGCGGGTACAGGTACGAACCGGTGAGGCGTCGTTGCCGATGCCTCACCGGCAGCAGGGTGGCAACGATGGCAAAGT
TCTTTCCAGCGCCACTATGG

Product: Glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MRYEDAAWREKQRIRLDVNNVFGTHGLTPAELEAEAPRAAAAIAAVQERRADLGWPLLPDQDVTPFEQFAAAHRDRIDTF
VVLGIGGSALGNIAVQTAINGPFYNLLPREQRGWPRLLVLDNSDPELNAGALRMLDLRRTMFNVISKSGTTAETMASFLY
FRQALVEAVGEDRLGDHIVLTTDPNSGFLRQIGQREGWTMFDLPPKVGGRFSVLTSVGLLSAAMTGVNIRELLAGAAYGR
ELAANPDPLRNPAALGALINYLCFRKGKPIVVMMPYANRLRDVADWFAQLWAESLGKAVDRQGKPARVGQTPVKALGATD
QHSQVQLYMEGPYDKLINFIAVEQYAETAPIPTAYADLEGVSYLGGHTMAELIQAEQQATAIALSEAGQPNITHIFPEIN
AFTLGQFFMLMEMQTAIAGELYDINAFDQPGVEAGKINTYALLGRRGFEERRAAIAARAQALDSRWVV

Sequences:

>Translated_468_residues
MRYEDAAWREKQRIRLDVNNVFGTHGLTPAELEAEAPRAAAAIAAVQERRADLGWPLLPDQDVTPFEQFAAAHRDRIDTF
VVLGIGGSALGNIAVQTAINGPFYNLLPREQRGWPRLLVLDNSDPELNAGALRMLDLRRTMFNVISKSGTTAETMASFLY
FRQALVEAVGEDRLGDHIVLTTDPNSGFLRQIGQREGWTMFDLPPKVGGRFSVLTSVGLLSAAMTGVNIRELLAGAAYGR
ELAANPDPLRNPAALGALINYLCFRKGKPIVVMMPYANRLRDVADWFAQLWAESLGKAVDRQGKPARVGQTPVKALGATD
QHSQVQLYMEGPYDKLINFIAVEQYAETAPIPTAYADLEGVSYLGGHTMAELIQAEQQATAIALSEAGQPNITHIFPEIN
AFTLGQFFMLMEMQTAIAGELYDINAFDQPGVEAGKINTYALLGRRGFEERRAAIAARAQALDSRWVV
>Mature_468_residues
MRYEDAAWREKQRIRLDVNNVFGTHGLTPAELEAEAPRAAAAIAAVQERRADLGWPLLPDQDVTPFEQFAAAHRDRIDTF
VVLGIGGSALGNIAVQTAINGPFYNLLPREQRGWPRLLVLDNSDPELNAGALRMLDLRRTMFNVISKSGTTAETMASFLY
FRQALVEAVGEDRLGDHIVLTTDPNSGFLRQIGQREGWTMFDLPPKVGGRFSVLTSVGLLSAAMTGVNIRELLAGAAYGR
ELAANPDPLRNPAALGALINYLCFRKGKPIVVMMPYANRLRDVADWFAQLWAESLGKAVDRQGKPARVGQTPVKALGATD
QHSQVQLYMEGPYDKLINFIAVEQYAETAPIPTAYADLEGVSYLGGHTMAELIQAEQQATAIALSEAGQPNITHIFPEIN
AFTLGQFFMLMEMQTAIAGELYDINAFDQPGVEAGKINTYALLGRRGFEERRAAIAARAQALDSRWVV

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=397, Percent_Identity=27.2040302267003, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1790457, Length=379, Percent_Identity=26.6490765171504, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71996703, Length=392, Percent_Identity=26.2755102040816, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71996708, Length=392, Percent_Identity=26.2755102040816, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319673, Length=382, Percent_Identity=26.9633507853403, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24651916, Length=422, Percent_Identity=27.4881516587678, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651914, Length=422, Percent_Identity=27.4881516587678, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17737445, Length=422, Percent_Identity=27.4881516587678, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 51315; Mature: 51315

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYEDAAWREKQRIRLDVNNVFGTHGLTPAELEAEAPRAAAAIAAVQERRADLGWPLLPD
CCCCCHHHHCCCEEEEEECHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
QDVTPFEQFAAAHRDRIDTFVVLGIGGSALGNIAVQTAINGPFYNLLPREQRGWPRLLVL
CCCCHHHHHHHHHHCCCCEEEEEECCCHHHCCEEEEEECCCCHHHCCCCCCCCCCEEEEE
DNSDPELNAGALRMLDLRRTMFNVISKSGTTAETMASFLYFRQALVEAVGEDRLGDHIVL
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
TTDPNSGFLRQIGQREGWTMFDLPPKVGGRFSVLTSVGLLSAAMTGVNIRELLAGAAYGR
EECCCCHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
ELAANPDPLRNPAALGALINYLCFRKGKPIVVMMPYANRLRDVADWFAQLWAESLGKAVD
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RQGKPARVGQTPVKALGATDQHSQVQLYMEGPYDKLINFIAVEQYAETAPIPTAYADLEG
CCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHCCCC
VSYLGGHTMAELIQAEQQATAIALSEAGQPNITHIFPEINAFTLGQFFMLMEMQTAIAGE
CHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCC
LYDINAFDQPGVEAGKINTYALLGRRGFEERRAAIAARAQALDSRWVV
EEECCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRYEDAAWREKQRIRLDVNNVFGTHGLTPAELEAEAPRAAAAIAAVQERRADLGWPLLPD
CCCCCHHHHCCCEEEEEECHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
QDVTPFEQFAAAHRDRIDTFVVLGIGGSALGNIAVQTAINGPFYNLLPREQRGWPRLLVL
CCCCHHHHHHHHHHCCCCEEEEEECCCHHHCCEEEEEECCCCHHHCCCCCCCCCCEEEEE
DNSDPELNAGALRMLDLRRTMFNVISKSGTTAETMASFLYFRQALVEAVGEDRLGDHIVL
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
TTDPNSGFLRQIGQREGWTMFDLPPKVGGRFSVLTSVGLLSAAMTGVNIRELLAGAAYGR
EECCCCHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
ELAANPDPLRNPAALGALINYLCFRKGKPIVVMMPYANRLRDVADWFAQLWAESLGKAVD
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RQGKPARVGQTPVKALGATDQHSQVQLYMEGPYDKLINFIAVEQYAETAPIPTAYADLEG
CCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHCCCC
VSYLGGHTMAELIQAEQQATAIALSEAGQPNITHIFPEINAFTLGQFFMLMEMQTAIAGE
CHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCC
LYDINAFDQPGVEAGKINTYALLGRRGFEERRAAIAARAQALDSRWVV
EEECCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA