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The map label for this gene is hldE [H]

Identifier: 222525596

GI number: 222525596

Start: 2969631

End: 2970161

Strand: Reverse

Name: hldE [H]

Synonym: Chy400_2346

Alternate gene names: 222525596

Gene position: 2970161-2969631 (Counterclockwise)

Preceding gene: 222525597

Following gene: 222525595

Centisome position: 56.37

GC content: 62.71

Gene sequence:

>531_bases
ATGAACATCTACCCGCTACCTGAACTGATTGCATTGCGTGCCACCTGGCGGGCCAGTGGTTTGAAAGTAGTGTTCACGAA
CGGTGTCTTTGATCTGCTCCACGTCGGGCACGTCCGGTATCTGACAGCAGCGCGTGCGCTTGGTGATCGACTGATCGTTG
CGATTAACAGCGACGAGTCCACCCGTCAATTGAAGGGATCGCTGCGCCCTATCGTCCCGGAGGCGGAGCGGGCAACGATT
GTAGCCGCGCTGCGCTGCGTTGATGCAGTGACCATCTTCAATGAGCGCACGGCGGAGGCAGTGGTAGCCGCGTTAGCGCC
CGATCTGTACGTGAAGGGGGGCGATTACGGGCAGGGAACCACATTTGACGCCGCCCGCCTACCCGAAGCGCGGGTCGTGC
AGGCGCTGGGAGGTGAGGTGCAGATTCTGCCGTTTAGCGAGGGGCACGCGACAACGCGGCTGATCGAGCGGATCGTTGCG
CGCTACGGGGGGGAGGGGGGGAACGCGGATGGGCGCGGGTTTGGCGGATGA

Upstream 100 bases:

>100_bases
TGACGGGCGAGCAGATTGGTCTGCTGGGAGGTGCGGTGCTGGTTGTGATGGTCTTGTGCTGGCTGGGTTTACCGCTTACG
TCGCCGTTTCGGGAACGACG

Downstream 100 bases:

>100_bases
ACGCGGATGTATCCCTTCTATCACCACAGTGGTGCGGATTGTTGGGCGCTGTGGAACACGGATGGACGCGGATTAGGCGG
ATGAACGCGGATGTATCTCT

Product: cytidyltransferase-related domain-containing protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MNIYPLPELIALRATWRASGLKVVFTNGVFDLLHVGHVRYLTAARALGDRLIVAINSDESTRQLKGSLRPIVPEAERATI
VAALRCVDAVTIFNERTAEAVVAALAPDLYVKGGDYGQGTTFDAARLPEARVVQALGGEVQILPFSEGHATTRLIERIVA
RYGGEGGNADGRGFGG

Sequences:

>Translated_176_residues
MNIYPLPELIALRATWRASGLKVVFTNGVFDLLHVGHVRYLTAARALGDRLIVAINSDESTRQLKGSLRPIVPEAERATI
VAALRCVDAVTIFNERTAEAVVAALAPDLYVKGGDYGQGTTFDAARLPEARVVQALGGEVQILPFSEGHATTRLIERIVA
RYGGEGGNADGRGFGG
>Mature_176_residues
MNIYPLPELIALRATWRASGLKVVFTNGVFDLLHVGHVRYLTAARALGDRLIVAINSDESTRQLKGSLRPIVPEAERATI
VAALRCVDAVTIFNERTAEAVVAALAPDLYVKGGDYGQGTTFDAARLPEARVVQALGGEVQILPFSEGHATTRLIERIVA
RYGGEGGNADGRGFGG

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=151, Percent_Identity=49.0066225165563, Blast_Score=136, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI193209647, Length=71, Percent_Identity=42.2535211267606, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533408, Length=71, Percent_Identity=42.2535211267606, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 18785; Mature: 18785

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIYPLPELIALRATWRASGLKVVFTNGVFDLLHVGHVRYLTAARALGDRLIVAINSDES
CCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCH
TRQLKGSLRPIVPEAERATIVAALRCVDAVTIFNERTAEAVVAALAPDLYVKGGDYGQGT
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCCC
TFDAARLPEARVVQALGGEVQILPFSEGHATTRLIERIVARYGGEGGNADGRGFGG
CCCHHHCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIYPLPELIALRATWRASGLKVVFTNGVFDLLHVGHVRYLTAARALGDRLIVAINSDES
CCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCH
TRQLKGSLRPIVPEAERATIVAALRCVDAVTIFNERTAEAVVAALAPDLYVKGGDYGQGT
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCCC
TFDAARLPEARVVQALGGEVQILPFSEGHATTRLIERIVARYGGEGGNADGRGFGG
CCCHHHCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA