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The map label for this gene is cutL [H]

Identifier: 222525521

GI number: 222525521

Start: 2871280

End: 2873610

Strand: Reverse

Name: cutL [H]

Synonym: Chy400_2270

Alternate gene names: 222525521

Gene position: 2873610-2871280 (Counterclockwise)

Preceding gene: 222525546

Following gene: 222525520

Centisome position: 54.54

GC content: 60.4

Gene sequence:

>2331_bases
ATGGCCTATGCAGCCCTGATCGGTGCTGAAGTCAAGCGCCGTGAAGACCCGCGTCTCGTGCAGGGGCAGGGCACATATGT
GAGCGATTTGCGCTTGCCGGGTATGCTTTATGTAGCAATTGCCCGTAGTCCGTATGCCCACGCCCGCATTGTCAGCATTG
ATAAGGCAACGGCTCTTACCTTGCCGGGAGTCGTTGCGGTCTATACCGGTACCGATCTCCTCGATCTCTGTCAGCCACTG
CCGTTAGCCAGTTCTGGCGAAGGTGGCAGTGGCCCCCAGCGCTATACCGGTCGCACTCGCTATGTGCTGGCCGTTGAGCG
AGTTCGTCACGTTGGCGAAGCAGTTGCCGCTGTGGTTGCGCATTCTCCGGAAGCAGCACTTGATGCGGCACTGGCTCTGG
CGATTGAATGGGAACCTCTCCCGGCAGTGGTTGATCCGCTAGCCGCCATCGATCCGGCAGCACCGGTGATCTTTGAAGAC
CTGCCCGATAACATTGACCATCGCCGCCGCCGCCAGAAGGGTGATGTCGAGGCTGCATTCGCCTCTGCCCATCGGGTTGT
TCGCCAACGAATGGTCAATCAGCGTCTGCTCGGTTTTCCGATGGAAGGCCGTGCTGTCGTGGCCGCCCCCGATCCAACGA
ACGACGGGGTAACCCTCTGGACGAGTACGCAGACCCCACATCAGGTACGTGGCGATGTCGCCAGGGTTATCGGGCTTGAT
GAGAATCGGGTGCGTGTTATCGCCCCCGATGTCGGTGGTGGCTTTGGGGTCAAGATCGGCATCTATCCCGAAGAGGCATT
GCTGGCCGCGTTAGCCCGCCAGCTTCACGCACCCCTACGCTGGGTTGAACATCGACTTGAGCACGTTCAGGCCACTACCC
ACGGTCGCGGTCAGGTGTGCGACATTGAAGCTGCCGTCACGGCTGAGGGGGAAATCACCGCATTGCGGATGCGCATCGTC
GCCGATCTCGGTGCCTACCCGCTTGCTCCCGGTTTGCCCGACCTGACCACCGCCATGGCTGTCGGGGTCTACAAGATTCC
CGCCGTTGATCTGGAAGCGGTATGCGTGTATACCAACACCACACCGGTTGCCGCCTACCGCGGCGCAGGCCGCCCGGAAG
CCGCTTACTACATCGAGCGTCTGATGGATCTGGTCGCTGCCGAGCTGAATCTGGACCCGGCAGAGGTGCGCCGGCGCAAT
TTTATCCCCCCGGATGCATTTCCGTACAAAACCCCGACCGGCCTGACCTACGACAGCGGTGAGTATGATCGGGCGCTGAC
CAAGGCGCTCAGCCTGGCCAATTACGAGCAATTACGCGCCGAGCAGGCCGCCCGCCGGGCTGCCGGTGATCGGATGTTGC
TCGGTATCGGAATCGCCTGTTATGTCGAAATGTGTGGCTTCGGCCCTTATGAGAGTGCCCAGATCAAGGTAGAGCCGAGT
GGTACCGTTACCGTCACCACCGGTATTTCACCGCACGGTCAGGGGACAGCCACGACCTTTGCCCAGATTGTCGCCGATCA
GATCGGCGCCGATTTCAACCGCATTGTCGTCAAACACAGCGACACTGCCCTGACGCCGATGGGTATCGGCACGATGGGAT
CACGCTCGCTCGCCGTGGGTGGCGCTGCGCTGGTACGTGCTGCAACCAAAGTGCGCGAGAAGGCTCGCCAGATTGCGGCT
GCAATGCTCGAAGCGAATGTGGCCGACATCGAGTTCCACGAAGGCCGGTATGTTGTCCGGGGTGTCCCCGACCGTGGGCT
GACGCTGACCGAGATTGCCCGCCGCGCCTACAGTAATAAACTGCCACCGGAGATTGATCCGGGTCTGGAAGCGGTTGACT
ATTTCCGCCCCGCTGACCTGATCTACCCCTTCGGCGCGCACGTCGCTGTCGTTGAAGTTGATAGCGAGACCGGCCATGTC
CGTATCCGGGACTACTATTCGGTTGATGATTGTGGGCCGCGGATCAGCCCGCTCATTGTCACCGGCCAGGTACACGGCGG
TCTGGCCCAGGGTATCGCCCAAGCCCTCCTTGAAGAGGTGGTGTACGATGCCAATGGTCAGTTGCTGAGCGGGACGCTAA
TGGATTACGCTGTACCACGGGCCGATCTCTTCCCGCCCTTCACCGTTGACAAGACGGAAACACCGACCCCCCTTAATCCT
CTCGGTGTGAAAGGGATCGGCGAAGCAGCTACCATCGGCTCGACACCGGCCATCACCAATGCGGTGATTGATGCGCTTCA
ACCGTTTGGTGTACGGCACATAGATATTCCGTTGCGGCCCGAAAAGGTCTGGCGGGCAATCAACAATGGACACCTCGAAA
AAGGAGAGTGA

Upstream 100 bases:

>100_bases
AGCCTCTTCAATTCGCCGGATAAGGCCGCAAATTCTGGTATCATGCCTGTAGTATCTAAGAAGGTTTCGTTGTTAACAAA
AAAGAAAGGCAGGTCGAACG

Downstream 100 bases:

>100_bases
TCGATGGCTGAGATGCTCCGCGAATCGCCGTATCCAATGGTCAGCATCGCCGAAGCCACAGCGACGATCATGGCGCAGGC
TCGTCCGCTGGCGAGTGAGG

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MAYAALIGAEVKRREDPRLVQGQGTYVSDLRLPGMLYVAIARSPYAHARIVSIDKATALTLPGVVAVYTGTDLLDLCQPL
PLASSGEGGSGPQRYTGRTRYVLAVERVRHVGEAVAAVVAHSPEAALDAALALAIEWEPLPAVVDPLAAIDPAAPVIFED
LPDNIDHRRRRQKGDVEAAFASAHRVVRQRMVNQRLLGFPMEGRAVVAAPDPTNDGVTLWTSTQTPHQVRGDVARVIGLD
ENRVRVIAPDVGGGFGVKIGIYPEEALLAALARQLHAPLRWVEHRLEHVQATTHGRGQVCDIEAAVTAEGEITALRMRIV
ADLGAYPLAPGLPDLTTAMAVGVYKIPAVDLEAVCVYTNTTPVAAYRGAGRPEAAYYIERLMDLVAAELNLDPAEVRRRN
FIPPDAFPYKTPTGLTYDSGEYDRALTKALSLANYEQLRAEQAARRAAGDRMLLGIGIACYVEMCGFGPYESAQIKVEPS
GTVTVTTGISPHGQGTATTFAQIVADQIGADFNRIVVKHSDTALTPMGIGTMGSRSLAVGGAALVRAATKVREKARQIAA
AMLEANVADIEFHEGRYVVRGVPDRGLTLTEIARRAYSNKLPPEIDPGLEAVDYFRPADLIYPFGAHVAVVEVDSETGHV
RIRDYYSVDDCGPRISPLIVTGQVHGGLAQGIAQALLEEVVYDANGQLLSGTLMDYAVPRADLFPPFTVDKTETPTPLNP
LGVKGIGEAATIGSTPAITNAVIDALQPFGVRHIDIPLRPEKVWRAINNGHLEKGE

Sequences:

>Translated_776_residues
MAYAALIGAEVKRREDPRLVQGQGTYVSDLRLPGMLYVAIARSPYAHARIVSIDKATALTLPGVVAVYTGTDLLDLCQPL
PLASSGEGGSGPQRYTGRTRYVLAVERVRHVGEAVAAVVAHSPEAALDAALALAIEWEPLPAVVDPLAAIDPAAPVIFED
LPDNIDHRRRRQKGDVEAAFASAHRVVRQRMVNQRLLGFPMEGRAVVAAPDPTNDGVTLWTSTQTPHQVRGDVARVIGLD
ENRVRVIAPDVGGGFGVKIGIYPEEALLAALARQLHAPLRWVEHRLEHVQATTHGRGQVCDIEAAVTAEGEITALRMRIV
ADLGAYPLAPGLPDLTTAMAVGVYKIPAVDLEAVCVYTNTTPVAAYRGAGRPEAAYYIERLMDLVAAELNLDPAEVRRRN
FIPPDAFPYKTPTGLTYDSGEYDRALTKALSLANYEQLRAEQAARRAAGDRMLLGIGIACYVEMCGFGPYESAQIKVEPS
GTVTVTTGISPHGQGTATTFAQIVADQIGADFNRIVVKHSDTALTPMGIGTMGSRSLAVGGAALVRAATKVREKARQIAA
AMLEANVADIEFHEGRYVVRGVPDRGLTLTEIARRAYSNKLPPEIDPGLEAVDYFRPADLIYPFGAHVAVVEVDSETGHV
RIRDYYSVDDCGPRISPLIVTGQVHGGLAQGIAQALLEEVVYDANGQLLSGTLMDYAVPRADLFPPFTVDKTETPTPLNP
LGVKGIGEAATIGSTPAITNAVIDALQPFGVRHIDIPLRPEKVWRAINNGHLEKGE
>Mature_775_residues
AYAALIGAEVKRREDPRLVQGQGTYVSDLRLPGMLYVAIARSPYAHARIVSIDKATALTLPGVVAVYTGTDLLDLCQPLP
LASSGEGGSGPQRYTGRTRYVLAVERVRHVGEAVAAVVAHSPEAALDAALALAIEWEPLPAVVDPLAAIDPAAPVIFEDL
PDNIDHRRRRQKGDVEAAFASAHRVVRQRMVNQRLLGFPMEGRAVVAAPDPTNDGVTLWTSTQTPHQVRGDVARVIGLDE
NRVRVIAPDVGGGFGVKIGIYPEEALLAALARQLHAPLRWVEHRLEHVQATTHGRGQVCDIEAAVTAEGEITALRMRIVA
DLGAYPLAPGLPDLTTAMAVGVYKIPAVDLEAVCVYTNTTPVAAYRGAGRPEAAYYIERLMDLVAAELNLDPAEVRRRNF
IPPDAFPYKTPTGLTYDSGEYDRALTKALSLANYEQLRAEQAARRAAGDRMLLGIGIACYVEMCGFGPYESAQIKVEPSG
TVTVTTGISPHGQGTATTFAQIVADQIGADFNRIVVKHSDTALTPMGIGTMGSRSLAVGGAALVRAATKVREKARQIAAA
MLEANVADIEFHEGRYVVRGVPDRGLTLTEIARRAYSNKLPPEIDPGLEAVDYFRPADLIYPFGAHVAVVEVDSETGHVR
IRDYYSVDDCGPRISPLIVTGQVHGGLAQGIAQALLEEVVYDANGQLLSGTLMDYAVPRADLFPPFTVDKTETPTPLNPL
GVKGIGEAATIGSTPAITNAVIDALQPFGVRHIDIPLRPEKVWRAINNGHLEKGE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=791, Percent_Identity=25.4108723135272, Blast_Score=156, Evalue=9e-38,
Organism=Homo sapiens, GI91823271, Length=789, Percent_Identity=23.574144486692, Blast_Score=132, Evalue=1e-30,
Organism=Escherichia coli, GI1789230, Length=760, Percent_Identity=30, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1789246, Length=810, Percent_Identity=26.9135802469136, Blast_Score=232, Evalue=8e-62,
Organism=Escherichia coli, GI1786478, Length=770, Percent_Identity=25.4545454545455, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17540638, Length=742, Percent_Identity=23.1805929919137, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17539860, Length=759, Percent_Identity=20.4216073781291, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI17737937, Length=758, Percent_Identity=27.8364116094987, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24647199, Length=728, Percent_Identity=24.4505494505494, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24647201, Length=791, Percent_Identity=23.6409608091024, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24647193, Length=715, Percent_Identity=23.0769230769231, Blast_Score=115, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 83185; Mature: 83054

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYAALIGAEVKRREDPRLVQGQGTYVSDLRLPGMLYVAIARSPYAHARIVSIDKATALT
CCCHHHHHHHHHCCCCCCEEECCCCEEECCCCCCEEEEEEECCCCCCEEEEEECCCCEEE
LPGVVAVYTGTDLLDLCQPLPLASSGEGGSGPQRYTGRTRYVLAVERVRHVGEAVAAVVA
CCCEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
HSPEAALDAALALAIEWEPLPAVVDPLAAIDPAAPVIFEDLPDNIDHRRRRQKGDVEAAF
CCCHHHHHEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCCCHHHHH
ASAHRVVRQRMVNQRLLGFPMEGRAVVAAPDPTNDGVTLWTSTQTPHQVRGDVARVIGLD
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHCCHHHHCCCC
ENRVRVIAPDVGGGFGVKIGIYPEEALLAALARQLHAPLRWVEHRLEHVQATTHGRGQVC
CCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
DIEAAVTAEGEITALRMRIVADLGAYPLAPGLPDLTTAMAVGVYKIPAVDLEAVCVYTNT
EEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCEEECCCCCEEEEEEEECC
TPVAAYRGAGRPEAAYYIERLMDLVAAELNLDPAEVRRRNFIPPDAFPYKTPTGLTYDSG
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCC
EYDRALTKALSLANYEQLRAEQAARRAAGDRMLLGIGIACYVEMCGFGPYESAQIKVEPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCCEEEECCC
GTVTVTTGISPHGQGTATTFAQIVADQIGADFNRIVVKHSDTALTPMGIGTMGSRSLAVG
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCEECCCCCCCCCCCCEECC
GAALVRAATKVREKARQIAAAMLEANVADIEFHEGRYVVRGVPDRGLTLTEIARRAYSNK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCCCHHHHHHHHHCCC
LPPEIDPGLEAVDYFRPADLIYPFGAHVAVVEVDSETGHVRIRDYYSVDDCGPRISPLIV
CCCCCCCCCHHHHHCCCCHHEEECCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEE
TGQVHGGLAQGIAQALLEEVVYDANGQLLSGTLMDYAVPRADLFPPFTVDKTETPTPLNP
EECCCCHHHHHHHHHHHHHHHHCCCCCEEECHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
LGVKGIGEAATIGSTPAITNAVIDALQPFGVRHIDIPLRPEKVWRAINNGHLEKGE
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AYAALIGAEVKRREDPRLVQGQGTYVSDLRLPGMLYVAIARSPYAHARIVSIDKATALT
CCHHHHHHHHHCCCCCCEEECCCCEEECCCCCCEEEEEEECCCCCCEEEEEECCCCEEE
LPGVVAVYTGTDLLDLCQPLPLASSGEGGSGPQRYTGRTRYVLAVERVRHVGEAVAAVVA
CCCEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
HSPEAALDAALALAIEWEPLPAVVDPLAAIDPAAPVIFEDLPDNIDHRRRRQKGDVEAAF
CCCHHHHHEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCCCHHHHH
ASAHRVVRQRMVNQRLLGFPMEGRAVVAAPDPTNDGVTLWTSTQTPHQVRGDVARVIGLD
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHCCHHHHCCCC
ENRVRVIAPDVGGGFGVKIGIYPEEALLAALARQLHAPLRWVEHRLEHVQATTHGRGQVC
CCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
DIEAAVTAEGEITALRMRIVADLGAYPLAPGLPDLTTAMAVGVYKIPAVDLEAVCVYTNT
EEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCEEECCCCCEEEEEEEECC
TPVAAYRGAGRPEAAYYIERLMDLVAAELNLDPAEVRRRNFIPPDAFPYKTPTGLTYDSG
CCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCC
EYDRALTKALSLANYEQLRAEQAARRAAGDRMLLGIGIACYVEMCGFGPYESAQIKVEPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCCEEEECCC
GTVTVTTGISPHGQGTATTFAQIVADQIGADFNRIVVKHSDTALTPMGIGTMGSRSLAVG
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCEECCCCCCCCCCCCEECC
GAALVRAATKVREKARQIAAAMLEANVADIEFHEGRYVVRGVPDRGLTLTEIARRAYSNK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCCCHHHHHHHHHCCC
LPPEIDPGLEAVDYFRPADLIYPFGAHVAVVEVDSETGHVRIRDYYSVDDCGPRISPLIV
CCCCCCCCCHHHHHCCCCHHEEECCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEE
TGQVHGGLAQGIAQALLEEVVYDANGQLLSGTLMDYAVPRADLFPPFTVDKTETPTPLNP
EECCCCHHHHHHHHHHHHHHHHCCCCCEEECHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
LGVKGIGEAATIGSTPAITNAVIDALQPFGVRHIDIPLRPEKVWRAINNGHLEKGE
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]