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The map label for this gene is aroB [H]

Identifier: 222525518

GI number: 222525518

Start: 2868787

End: 2869905

Strand: Reverse

Name: aroB [H]

Synonym: Chy400_2267

Alternate gene names: 222525518

Gene position: 2869905-2868787 (Counterclockwise)

Preceding gene: 222525519

Following gene: 222525517

Centisome position: 54.47

GC content: 61.57

Gene sequence:

>1119_bases
ATGATCACAACCACGCTCACAGTTACGACCAGCACAACTTCCTACCCGGTCATCGTCGGGGCAGGTATCCTGTCCAACCT
CGCCGACTACCTGGCTGAATGCGCCCTGCGCGGGACAGCCTGGATTGTTGCCGATGAACACCTGACCGCCATTGCCGATC
AGACCGCAGCCCACCTGACAGCAGCCGGGTATCGCGTTCACACGACCACTGTGCCATCAGGTGAACAGAGCAAATCGTTC
GGCGAACTGAACCGACTGTACGACTGGATGATCGAACACGGAATCGAACGCCGTGATGTCGTCCTGGCCCTCGGTGGTGG
CGTGGTCGGTGACCTGGCAGGGTTTGCGGCAGCGACCATCTTGCGCGGTGTGGCCCTCGTCCAGATACCGAGCACGCTCC
TGGCGATGGTTGATGCTGCGGTAGGTGGTAAAACCGGCATCAACCACCCGCTGGGCAAAAACCTGATCGGAGCCTTTCAT
CAACCACGGCTGGTGTTGGCCGACACCAACCTGCTGGCGACACTACCGGCTCGCGAGCTACGCGCCGGCTGGGCCGAAGT
GATCAAACACGGTGTCATTCGCGATGCCGAATTGTTTGACGCCCTGGAAACACTCGCCGCAACCCAACGCTGGCACGCCG
ACAATCCGGCTACCTGGGATGCGACCGATCCGGCCCTCACCGGTGAACTGACCAACATCATCGCCCGCGCTGTTGCGGTC
AAAGTCGACGTTGTATCACGTGATGAATTTGAACGCGGCGAACGCATCACCCTCAATTACGGACATACCATTGGTCACGC
CATCGAGCAACTGCTTGGGTATCGCCTCCTGCACGGCGAATGCGTCGCCATCGGCATGGATGCCGCTGCGCGCATTGCCG
TCGCCCTGGGCATCTGCCCGCCGGCCCTGGTCGAACGACAGCGTAACCTCCTCGCCGCCTACGGCCTATCAACCGCGCTG
CCGGCAGACCTTGACCGCAGTGCGATCCTGACCCTCATCGGTCGTGACAAAAAGGTACAGGCCGGAAATGTGCGCTGGGT
CTTGCCAACCGCTATCGGTCAGGTCGTCGTGCGCGCCGACGTGCCGCTTGCGGTGGTTGAAGCGGTGCTGGCGGGGTAA

Upstream 100 bases:

>100_bases
ACCGTGGCCCGGTCCACTGACATATCTTGGTATCGCCCTTTTACTGATTGCGGCGCTGATGACGATCATCAATCGGCGTC
GCAAACCCTGACAGCGAACA

Downstream 100 bases:

>100_bases
TACGGTGAGCAATACCGCTACTGAACGCCTTTCAGTGTGCTACAATGTAAAGCGTTTACTCGCCGCAGCAAGCCAAAAAT
TCCTGTACCGGGCAGATTGT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MITTTLTVTTSTTSYPVIVGAGILSNLADYLAECALRGTAWIVADEHLTAIADQTAAHLTAAGYRVHTTTVPSGEQSKSF
GELNRLYDWMIEHGIERRDVVLALGGGVVGDLAGFAAATILRGVALVQIPSTLLAMVDAAVGGKTGINHPLGKNLIGAFH
QPRLVLADTNLLATLPARELRAGWAEVIKHGVIRDAELFDALETLAATQRWHADNPATWDATDPALTGELTNIIARAVAV
KVDVVSRDEFERGERITLNYGHTIGHAIEQLLGYRLLHGECVAIGMDAAARIAVALGICPPALVERQRNLLAAYGLSTAL
PADLDRSAILTLIGRDKKVQAGNVRWVLPTAIGQVVVRADVPLAVVEAVLAG

Sequences:

>Translated_372_residues
MITTTLTVTTSTTSYPVIVGAGILSNLADYLAECALRGTAWIVADEHLTAIADQTAAHLTAAGYRVHTTTVPSGEQSKSF
GELNRLYDWMIEHGIERRDVVLALGGGVVGDLAGFAAATILRGVALVQIPSTLLAMVDAAVGGKTGINHPLGKNLIGAFH
QPRLVLADTNLLATLPARELRAGWAEVIKHGVIRDAELFDALETLAATQRWHADNPATWDATDPALTGELTNIIARAVAV
KVDVVSRDEFERGERITLNYGHTIGHAIEQLLGYRLLHGECVAIGMDAAARIAVALGICPPALVERQRNLLAAYGLSTAL
PADLDRSAILTLIGRDKKVQAGNVRWVLPTAIGQVVVRADVPLAVVEAVLAG
>Mature_372_residues
MITTTLTVTTSTTSYPVIVGAGILSNLADYLAECALRGTAWIVADEHLTAIADQTAAHLTAAGYRVHTTTVPSGEQSKSF
GELNRLYDWMIEHGIERRDVVLALGGGVVGDLAGFAAATILRGVALVQIPSTLLAMVDAAVGGKTGINHPLGKNLIGAFH
QPRLVLADTNLLATLPARELRAGWAEVIKHGVIRDAELFDALETLAATQRWHADNPATWDATDPALTGELTNIIARAVAV
KVDVVSRDEFERGERITLNYGHTIGHAIEQLLGYRLLHGECVAIGMDAAARIAVALGICPPALVERQRNLLAAYGLSTAL
PADLDRSAILTLIGRDKKVQAGNVRWVLPTAIGQVVVRADVPLAVVEAVLAG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=361, Percent_Identity=42.9362880886427, Blast_Score=237, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6320332, Length=318, Percent_Identity=40.251572327044, Blast_Score=205, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39359; Mature: 39359

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTTLTVTTSTTSYPVIVGAGILSNLADYLAECALRGTAWIVADEHLTAIADQTAAHLT
CEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHH
AAGYRVHTTTVPSGEQSKSFGELNRLYDWMIEHGIERRDVVLALGGGVVGDLAGFAAATI
HCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHH
LRGVALVQIPSTLLAMVDAAVGGKTGINHPLGKNLIGAFHQPRLVLADTNLLATLPAREL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEECCCEEEECCHHHH
RAGWAEVIKHGVIRDAELFDALETLAATQRWHADNPATWDATDPALTGELTNIIARAVAV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KVDVVSRDEFERGERITLNYGHTIGHAIEQLLGYRLLHGECVAIGMDAAARIAVALGICP
EEEEECCCHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCC
PALVERQRNLLAAYGLSTALPADLDRSAILTLIGRDKKVQAGNVRWVLPTAIGQVVVRAD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEECCCCEEECCCEEEEEHHHHCCEEEECC
VPLAVVEAVLAG
CCHHHHHHHHCC
>Mature Secondary Structure
MITTTLTVTTSTTSYPVIVGAGILSNLADYLAECALRGTAWIVADEHLTAIADQTAAHLT
CEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHH
AAGYRVHTTTVPSGEQSKSFGELNRLYDWMIEHGIERRDVVLALGGGVVGDLAGFAAATI
HCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHH
LRGVALVQIPSTLLAMVDAAVGGKTGINHPLGKNLIGAFHQPRLVLADTNLLATLPAREL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEECCCEEEECCHHHH
RAGWAEVIKHGVIRDAELFDALETLAATQRWHADNPATWDATDPALTGELTNIIARAVAV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KVDVVSRDEFERGERITLNYGHTIGHAIEQLLGYRLLHGECVAIGMDAAARIAVALGICP
EEEEECCCHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCC
PALVERQRNLLAAYGLSTALPADLDRSAILTLIGRDKKVQAGNVRWVLPTAIGQVVVRAD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEECCCCEEECCCEEEEEHHHHCCEEEECC
VPLAVVEAVLAG
CCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA