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The map label for this gene is trxB [H]

Identifier: 222525479

GI number: 222525479

Start: 2820181

End: 2821134

Strand: Direct

Name: trxB [H]

Synonym: Chy400_2227

Alternate gene names: 222525479

Gene position: 2820181-2821134 (Clockwise)

Preceding gene: 222525478

Following gene: 222525480

Centisome position: 53.52

GC content: 55.77

Gene sequence:

>954_bases
ATGCATCACAAAGTCGTTATTATTGGCTCTGGCCCGGCTGGCCTGACGGCGGCGCTCTATGCTGCGCGGGCGAATCTTGA
ACCGCTGGTCATTCGTGGCCTGCAACCGGGTGGTTTGATTGCCACGACCAGTGAAGTTGAGAATTACCCTGGTTTTGTTG
ATGGGATTGGTGGTTTCGAGCTGGCCGAGGCGATGGAGAAACAGGCGGCCCGTTTCGGTGCCCAATTCCTCGACTCGCTG
GTGACGAAAGTAGAGGTTGCCCAGCGCCCCTTTACCATTCATACCGATAGCGGGCAGACGGTTACTGCCGATGCGATTAT
CGTCAGCACCGGCGCCTCGCCACGGAAGCTCGGTGTACCGGGTGAAGAAGAGCTGGCCAATCGCGGCGTCAGCTATTGTG
CCACCTGCGATGGCTTTTTCTTCCGGGGCAAGAAGGTCGTCGTTGTTGGTGGCGGAAACAGTGCGCTTGATGAGGGTTTG
TTCCTGACCCGGTATGTCGATGAATTAGTGATTGTTCATCGCCGCGACACGCTGCGCGCCGATCCAATTTTACAGGAACG
GGCATTTAGTAATCCAAAAGTGCGTTTTATCTGGAATTCAGTGGTAGTTTCGATTAATGGCAAAGATAAAGTTGAGTCGG
TGACATTGCGCAATCTACAAACCGGTGAGGTGAGTGAATTACCGACCGATGGGGTATTTCCGTATATCGGCCACGTGCCT
AATACGGACTTGTTCCGCGGCATCCTTGAGCTTGACGAGGGTGGGTATATCGTGACCGATGGTCGTACCCGTACCAACAT
TCCCGGCATCTTTGCTGCGGGTGATGTGACCGATCACATCTATCGACAGGCCGTTACGGCTGCCGGCGATGGCTGCCGGG
CTGCGATGGAGGCGACCTGGTATCTGGCCGAGCAAGAGCATGCCCGCTCGAAAGCAACGGTGTCGGTCGCCTGA

Upstream 100 bases:

>100_bases
CACGCTTCGCCCGTGTTATACTCCTTCTTGCTGGCGGCGATGAAAGCGTCGCACAGTGAGATTATTGTGTGAATAATGCT
GTTGCAAGGAGACGGTTGAT

Downstream 100 bases:

>100_bases
CATGGTTGCGAATTTTATCTCTTCACAGAGGGTAAGGGTGTCGCTATAATAAGGCTACGACAACACCAAAGGAGGTGCCT
ATGACAGCGACACCCAATAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MHHKVVIIGSGPAGLTAALYAARANLEPLVIRGLQPGGLIATTSEVENYPGFVDGIGGFELAEAMEKQAARFGAQFLDSL
VTKVEVAQRPFTIHTDSGQTVTADAIIVSTGASPRKLGVPGEEELANRGVSYCATCDGFFFRGKKVVVVGGGNSALDEGL
FLTRYVDELVIVHRRDTLRADPILQERAFSNPKVRFIWNSVVVSINGKDKVESVTLRNLQTGEVSELPTDGVFPYIGHVP
NTDLFRGILELDEGGYIVTDGRTRTNIPGIFAAGDVTDHIYRQAVTAAGDGCRAAMEATWYLAEQEHARSKATVSVA

Sequences:

>Translated_317_residues
MHHKVVIIGSGPAGLTAALYAARANLEPLVIRGLQPGGLIATTSEVENYPGFVDGIGGFELAEAMEKQAARFGAQFLDSL
VTKVEVAQRPFTIHTDSGQTVTADAIIVSTGASPRKLGVPGEEELANRGVSYCATCDGFFFRGKKVVVVGGGNSALDEGL
FLTRYVDELVIVHRRDTLRADPILQERAFSNPKVRFIWNSVVVSINGKDKVESVTLRNLQTGEVSELPTDGVFPYIGHVP
NTDLFRGILELDEGGYIVTDGRTRTNIPGIFAAGDVTDHIYRQAVTAAGDGCRAAMEATWYLAEQEHARSKATVSVA
>Mature_317_residues
MHHKVVIIGSGPAGLTAALYAARANLEPLVIRGLQPGGLIATTSEVENYPGFVDGIGGFELAEAMEKQAARFGAQFLDSL
VTKVEVAQRPFTIHTDSGQTVTADAIIVSTGASPRKLGVPGEEELANRGVSYCATCDGFFFRGKKVVVVGGGNSALDEGL
FLTRYVDELVIVHRRDTLRADPILQERAFSNPKVRFIWNSVVVSINGKDKVESVTLRNLQTGEVSELPTDGVFPYIGHVP
NTDLFRGILELDEGGYIVTDGRTRTNIPGIFAAGDVTDHIYRQAVTAAGDGCRAAMEATWYLAEQEHARSKATVSVA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=47.2668810289389, Blast_Score=280, Evalue=9e-77,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=35.0819672131148, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6320560, Length=318, Percent_Identity=43.3962264150943, Blast_Score=277, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321898, Length=318, Percent_Identity=43.3962264150943, Blast_Score=271, Evalue=1e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33991; Mature: 33991

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHKVVIIGSGPAGLTAALYAARANLEPLVIRGLQPGGLIATTSEVENYPGFVDGIGGFE
CCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHCCCCHHCCCCCHH
LAEAMEKQAARFGAQFLDSLVTKVEVAQRPFTIHTDSGQTVTADAIIVSTGASPRKLGVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCC
GEEELANRGVSYCATCDGFFFRGKKVVVVGGGNSALDEGLFLTRYVDELVIVHRRDTLRA
CHHHHHHCCCCEEEECCCEEECCCEEEEEECCCCHHHCCCHHHHHHHHHHEEECCCCCCC
DPILQERAFSNPKVRFIWNSVVVSINGKDKVESVTLRNLQTGEVSELPTDGVFPYIGHVP
CCCHHHHCCCCCCEEEEEEEEEEEECCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCCCC
NTDLFRGILELDEGGYIVTDGRTRTNIPGIFAAGDVTDHIYRQAVTAAGDGCRAAMEATW
CHHHHHHHHEECCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHEE
YLAEQEHARSKATVSVA
EEHHHHHCCCCEEEEEC
>Mature Secondary Structure
MHHKVVIIGSGPAGLTAALYAARANLEPLVIRGLQPGGLIATTSEVENYPGFVDGIGGFE
CCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHCCCCHHCCCCCHH
LAEAMEKQAARFGAQFLDSLVTKVEVAQRPFTIHTDSGQTVTADAIIVSTGASPRKLGVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEECCCCCCCCCCC
GEEELANRGVSYCATCDGFFFRGKKVVVVGGGNSALDEGLFLTRYVDELVIVHRRDTLRA
CHHHHHHCCCCEEEECCCEEECCCEEEEEECCCCHHHCCCHHHHHHHHHHEEECCCCCCC
DPILQERAFSNPKVRFIWNSVVVSINGKDKVESVTLRNLQTGEVSELPTDGVFPYIGHVP
CCCHHHHCCCCCCEEEEEEEEEEEECCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCCCC
NTDLFRGILELDEGGYIVTDGRTRTNIPGIFAAGDVTDHIYRQAVTAAGDGCRAAMEATW
CHHHHHHHHEECCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHEE
YLAEQEHARSKATVSVA
EEHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA