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The map label for this gene is coaA [H]

Identifier: 222525455

GI number: 222525455

Start: 2792933

End: 2793889

Strand: Reverse

Name: coaA [H]

Synonym: Chy400_2203

Alternate gene names: 222525455

Gene position: 2793889-2792933 (Counterclockwise)

Preceding gene: 222525456

Following gene: 222525454

Centisome position: 53.03

GC content: 51.2

Gene sequence:

>957_bases
ATGATCCTGAAGTCAGAATTTGAACGCCGCCTTTCACCATACATGAGTTTTTCGCGCTCAGAATGGGCAGCACTTCGTAA
CGGTACTCCCTTACCACTCAGTGCAGACGAGTTAGACACGCTGGTCAGTCTGAATGACACCGTCTCAATGGAAGACGTTG
CCGACATCTACCTGCCACTGGTGCGCCTGCTACAAATCTACTACGACAATGCCTGTCGATTGTACCAGGCCACCAGTGCA
TTTCTCGGCTCAGGGACAGCACGAGTACCGTATGTGATCGGCATTGCCGGTAGTGTCGCGGTAGGGAAGAGCAGCACAGC
GCGCATCCTGCAAGCGCTCCTGGCGCGTGGGCCTGGACGCCTCAAAGTCGATCTGATTACAACCGACGGCTTTCTTTACC
CAAACCGAATCCTCCAGGAACGGGGGATTATGCACCGTAAAGGGTTTCCTGAAAGCTATGATCGGCGACGCCTCTTGCAG
TTTATGGCCGATATTAAATCGGGGTATGGCCCGGTGAGTGCGCCAGTCTATTCACACCTTATCTACGATATCGTGCCCGA
TCAAACGCAGGTTGTTGATCATCCAGATGTTCTGATTGTTGAAGGGTTGAATGTGTTACAGCGTGGTTCCAATACTCGAC
GCGAACCACAACTCTATGTATCAGACTTCTTTGACTTCGCGATTTATGTCGATGCCGATGAACGCGATCTTGAACAGTGG
TACATTGAACGATTTTTACGGCTGCGTGAAACGGCCTTTCGCGATCCGTCGTCATACTTTCGCCGCTACGCTGAGCTGAA
CGAAGAGGAAGCTATCGCTACCGCACGACGTATCTGGCGCGAAATTAATTATGTCAATTTAAAACAAAACATAGAACCGA
CGCGCTGGAGCGCCGATCTGATTCTGGTCAAAGGACCTCGCCACGAACTAGAGCGAGTCTATCTTCGCAAACTGTAG

Upstream 100 bases:

>100_bases
TTCTGAGCGCACTACCACGCGGTGCCACCGGAAAACTACAACGGATCACGATGGCGAAAACACTGGGATTGTAAGCAACG
GGAGAAAGACAGGAACCGGC

Downstream 100 bases:

>100_bases
GAACACGTACAAGGAGTAGCGGATCATATGCGCATCTGTATTGTTGGCGCCGGAGCGATTGGTGGCTGGTTGGGGGCAAA
GCTGATCCAGGCCGGAGCCG

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MILKSEFERRLSPYMSFSRSEWAALRNGTPLPLSADELDTLVSLNDTVSMEDVADIYLPLVRLLQIYYDNACRLYQATSA
FLGSGTARVPYVIGIAGSVAVGKSSTARILQALLARGPGRLKVDLITTDGFLYPNRILQERGIMHRKGFPESYDRRRLLQ
FMADIKSGYGPVSAPVYSHLIYDIVPDQTQVVDHPDVLIVEGLNVLQRGSNTRREPQLYVSDFFDFAIYVDADERDLEQW
YIERFLRLRETAFRDPSSYFRRYAELNEEEAIATARRIWREINYVNLKQNIEPTRWSADLILVKGPRHELERVYLRKL

Sequences:

>Translated_318_residues
MILKSEFERRLSPYMSFSRSEWAALRNGTPLPLSADELDTLVSLNDTVSMEDVADIYLPLVRLLQIYYDNACRLYQATSA
FLGSGTARVPYVIGIAGSVAVGKSSTARILQALLARGPGRLKVDLITTDGFLYPNRILQERGIMHRKGFPESYDRRRLLQ
FMADIKSGYGPVSAPVYSHLIYDIVPDQTQVVDHPDVLIVEGLNVLQRGSNTRREPQLYVSDFFDFAIYVDADERDLEQW
YIERFLRLRETAFRDPSSYFRRYAELNEEEAIATARRIWREINYVNLKQNIEPTRWSADLILVKGPRHELERVYLRKL
>Mature_318_residues
MILKSEFERRLSPYMSFSRSEWAALRNGTPLPLSADELDTLVSLNDTVSMEDVADIYLPLVRLLQIYYDNACRLYQATSA
FLGSGTARVPYVIGIAGSVAVGKSSTARILQALLARGPGRLKVDLITTDGFLYPNRILQERGIMHRKGFPESYDRRRLLQ
FMADIKSGYGPVSAPVYSHLIYDIVPDQTQVVDHPDVLIVEGLNVLQRGSNTRREPQLYVSDFFDFAIYVDADERDLEQW
YIERFLRLRETAFRDPSSYFRRYAELNEEEAIATARRIWREINYVNLKQNIEPTRWSADLILVKGPRHELERVYLRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=308, Percent_Identity=57.1428571428571, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 36708; Mature: 36708

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKSEFERRLSPYMSFSRSEWAALRNGTPLPLSADELDTLVSLNDTVSMEDVADIYLPL
CCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
VRLLQIYYDNACRLYQATSAFLGSGTARVPYVIGIAGSVAVGKSSTARILQALLARGPGR
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHCCCCC
LKVDLITTDGFLYPNRILQERGIMHRKGFPESYDRRRLLQFMADIKSGYGPVSAPVYSHL
EEEEEEECCCCCCHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
IYDIVPDQTQVVDHPDVLIVEGLNVLQRGSNTRREPQLYVSDFFDFAIYVDADERDLEQW
HHHHCCCCCEECCCCCEEEECCHHHHHCCCCCCCCCHHHHHHHEEEEEEECCCHHHHHHH
YIERFLRLRETAFRDPSSYFRRYAELNEEEAIATARRIWREINYVNLKQNIEPTRWSADL
HHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCE
ILVKGPRHELERVYLRKL
EEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MILKSEFERRLSPYMSFSRSEWAALRNGTPLPLSADELDTLVSLNDTVSMEDVADIYLPL
CCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
VRLLQIYYDNACRLYQATSAFLGSGTARVPYVIGIAGSVAVGKSSTARILQALLARGPGR
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHCCCCC
LKVDLITTDGFLYPNRILQERGIMHRKGFPESYDRRRLLQFMADIKSGYGPVSAPVYSHL
EEEEEEECCCCCCHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
IYDIVPDQTQVVDHPDVLIVEGLNVLQRGSNTRREPQLYVSDFFDFAIYVDADERDLEQW
HHHHCCCCCEECCCCCEEEECCHHHHHCCCCCCCCCHHHHHHHEEEEEEECCCHHHHHHH
YIERFLRLRETAFRDPSSYFRRYAELNEEEAIATARRIWREINYVNLKQNIEPTRWSADL
HHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCE
ILVKGPRHELERVYLRKL
EEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA