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The map label for this gene is nuoD1

Identifier: 222525394

GI number: 222525394

Start: 2717996

End: 2719105

Strand: Reverse

Name: nuoD1

Synonym: Chy400_2139

Alternate gene names: 222525394

Gene position: 2719105-2717996 (Counterclockwise)

Preceding gene: 222525395

Following gene: 222525393

Centisome position: 51.61

GC content: 54.68

Gene sequence:

>1110_bases
ATGCTCCAAACGCAAGAGCTGCAAGTCAATATTGGGCCACAACATCCATCAACTCACGGTGTCTTCCGCATGCTGGTGAC
GGTTGATGGTGAGACGGTGGTTGATCTTAAGCCGGTGTTCGGGTATCTGCACCGCAATCACGAGCAGATTGCCGAAGCGA
ATTCGTATCTGCAAAATATGCCCTATACCGACCGGCTCGACTATTTTAATTCGATGGCCAACAATCACGCCTATGCGATG
GCGGTCGAGCGATTGGCCGGGATTGAGGTGCCTGAACGGGCAGAGTACATCCGGGTGCTGATGGTCGAGCTAACCCGTAT
CCTCAATCACGCGAGTGCGGTTGGTTTCATGATCAACGATATGGGGGCCTGGCAGACGCCGCTGGCATTCGGGATGCGCG
AGCGAGAGAAGATTCTCGATCTGTTCGAGATGGCAAGCGGTGCCCGTTTGATGTGCAACTATTTTCGCTTCGGCGGTGTG
GTGCGCGATCTGCCCCCTGAATTCATTCCCAATTTGCGCGAGTTGTTGATCGCACTGCCGGCCTATATTGATGAGCTAGA
GCGGTTATTACGCGATAATGAGATTCTGTTACAACGGGCAATCGGCATCGGTATCCTGCCCCGTGAAGTCGCGCTCTCGT
ATGGCGTGACCGGCCCGGTGTTGCGCGGTTCGGGCATTCCCTACGATGTACGCAAAGCCGAACCGTACAGTGTTTACGAC
CGCTTCGATTTCGATATTCCCGTCGGTAAAGTAGGTGATGTTTATGACCGTTTTCTGGTACGCATTGAAGAGATGCGCCA
GAGTAAACGGATCATTGAACAGGTGCTTGAGCAGTTGCCAGATGCGAAGGGCGGGCACATCAACCCCAAGGCCCGCCAGA
ATGTCCGGCCACCGGTCGGTGATGCGTATGCCCGCATTGAGTCGCCAAAAGGCGAATTGGGCTTCTACCTGGTCAGCGAC
GGGAGTGGAAAACCGTACCGTTACAAAGTGCGAGCACCGTCGTTTATCAACCTGACGCCCCTGGCCGATATGTGTCGTGG
GTACAAGGTGGCCGATATTGTGGTCATTCTCGGCAGCATCGACATCGTGATGGGAGAGGTGGATCGATGA

Upstream 100 bases:

>100_bases
CAAATATCTGGGTAGCGACGAATAGTCAGGCTTGATTGTCAATACTATTGTTCATATCTTCGCTTGCAAGAAGCGATACC
CATAGAGAACTGGTGTCGAT

Downstream 100 bases:

>100_bases
CAGCACCACCATTCGAGATAGAGATTCCACGTGGGCGTGTGATTGAGGTGCAGCGCGATGACACCCGTGTCCGACGGGGC
AGTGGTTTGCTGCGGGGGAT

Product: NADH dehydrogenase I subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D 1; NDH-1 subunit D 1

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MLQTQELQVNIGPQHPSTHGVFRMLVTVDGETVVDLKPVFGYLHRNHEQIAEANSYLQNMPYTDRLDYFNSMANNHAYAM
AVERLAGIEVPERAEYIRVLMVELTRILNHASAVGFMINDMGAWQTPLAFGMREREKILDLFEMASGARLMCNYFRFGGV
VRDLPPEFIPNLRELLIALPAYIDELERLLRDNEILLQRAIGIGILPREVALSYGVTGPVLRGSGIPYDVRKAEPYSVYD
RFDFDIPVGKVGDVYDRFLVRIEEMRQSKRIIEQVLEQLPDAKGGHINPKARQNVRPPVGDAYARIESPKGELGFYLVSD
GSGKPYRYKVRAPSFINLTPLADMCRGYKVADIVVILGSIDIVMGEVDR

Sequences:

>Translated_369_residues
MLQTQELQVNIGPQHPSTHGVFRMLVTVDGETVVDLKPVFGYLHRNHEQIAEANSYLQNMPYTDRLDYFNSMANNHAYAM
AVERLAGIEVPERAEYIRVLMVELTRILNHASAVGFMINDMGAWQTPLAFGMREREKILDLFEMASGARLMCNYFRFGGV
VRDLPPEFIPNLRELLIALPAYIDELERLLRDNEILLQRAIGIGILPREVALSYGVTGPVLRGSGIPYDVRKAEPYSVYD
RFDFDIPVGKVGDVYDRFLVRIEEMRQSKRIIEQVLEQLPDAKGGHINPKARQNVRPPVGDAYARIESPKGELGFYLVSD
GSGKPYRYKVRAPSFINLTPLADMCRGYKVADIVVILGSIDIVMGEVDR
>Mature_369_residues
MLQTQELQVNIGPQHPSTHGVFRMLVTVDGETVVDLKPVFGYLHRNHEQIAEANSYLQNMPYTDRLDYFNSMANNHAYAM
AVERLAGIEVPERAEYIRVLMVELTRILNHASAVGFMINDMGAWQTPLAFGMREREKILDLFEMASGARLMCNYFRFGGV
VRDLPPEFIPNLRELLIALPAYIDELERLLRDNEILLQRAIGIGILPREVALSYGVTGPVLRGSGIPYDVRKAEPYSVYD
RFDFDIPVGKVGDVYDRFLVRIEEMRQSKRIIEQVLEQLPDAKGGHINPKARQNVRPPVGDAYARIESPKGELGFYLVSD
GSGKPYRYKVRAPSFINLTPLADMCRGYKVADIVVILGSIDIVMGEVDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=390, Percent_Identity=45.6410256410256, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI260898743, Length=384, Percent_Identity=44.7916666666667, Blast_Score=313, Evalue=1e-85,
Organism=Escherichia coli, GI145693162, Length=384, Percent_Identity=42.4479166666667, Blast_Score=293, Evalue=8e-81,
Organism=Escherichia coli, GI1789076, Length=364, Percent_Identity=30.4945054945055, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1788832, Length=368, Percent_Identity=29.8913043478261, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17568379, Length=390, Percent_Identity=44.1025641025641, Blast_Score=335, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17555284, Length=387, Percent_Identity=43.1524547803618, Blast_Score=332, Evalue=1e-91,
Organism=Drosophila melanogaster, GI24638644, Length=390, Percent_Identity=44.8717948717949, Blast_Score=342, Evalue=3e-94,
Organism=Drosophila melanogaster, GI221459469, Length=383, Percent_Identity=44.6475195822454, Blast_Score=335, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD1_CHLAA (A9WED7)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001635588.1
- ProteinModelPortal:   A9WED7
- SMR:   A9WED7
- GeneID:   5826435
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1984
- HOGENOM:   HBG459705
- OMA:   FGPFLAD
- ProtClustDB:   CLSK935598
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 41748; Mature: 41748

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTQELQVNIGPQHPSTHGVFRMLVTVDGETVVDLKPVFGYLHRNHEQIAEANSYLQNM
CCCCCEEEEEECCCCCCCHHHEEEEEEECCCEEEEHHHHHHHHHCCHHHHHHHHHHHHCC
PYTDRLDYFNSMANNHAYAMAVERLAGIEVPERAEYIRVLMVELTRILNHASAVGFMIND
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MGAWQTPLAFGMREREKILDLFEMASGARLMCNYFRFGGVVRDLPPEFIPNLRELLIALP
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHH
AYIDELERLLRDNEILLQRAIGIGILPREVALSYGVTGPVLRGSGIPYDVRKAEPYSVYD
HHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHH
RFDFDIPVGKVGDVYDRFLVRIEEMRQSKRIIEQVLEQLPDAKGGHINPKARQNVRPPVG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCC
DAYARIESPKGELGFYLVSDGSGKPYRYKVRAPSFINLTPLADMCRGYKVADIVVILGSI
HHHHHCCCCCCCEEEEEEECCCCCCEEEEECCCCEEECCCHHHHHCCCCHHHHHHHCCCH
DIVMGEVDR
HEEECCCCC
>Mature Secondary Structure
MLQTQELQVNIGPQHPSTHGVFRMLVTVDGETVVDLKPVFGYLHRNHEQIAEANSYLQNM
CCCCCEEEEEECCCCCCCHHHEEEEEEECCCEEEEHHHHHHHHHCCHHHHHHHHHHHHCC
PYTDRLDYFNSMANNHAYAMAVERLAGIEVPERAEYIRVLMVELTRILNHASAVGFMIND
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MGAWQTPLAFGMREREKILDLFEMASGARLMCNYFRFGGVVRDLPPEFIPNLRELLIALP
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHH
AYIDELERLLRDNEILLQRAIGIGILPREVALSYGVTGPVLRGSGIPYDVRKAEPYSVYD
HHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHH
RFDFDIPVGKVGDVYDRFLVRIEEMRQSKRIIEQVLEQLPDAKGGHINPKARQNVRPPVG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCC
DAYARIESPKGELGFYLVSDGSGKPYRYKVRAPSFINLTPLADMCRGYKVADIVVILGSI
HHHHHCCCCCCCEEEEEEECCCCCCEEEEECCCCEEECCCHHHHHCCCCHHHHHHHCCCH
DIVMGEVDR
HEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA