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The map label for this gene is murA [H]

Identifier: 222525316

GI number: 222525316

Start: 2612115

End: 2613407

Strand: Direct

Name: murA [H]

Synonym: Chy400_2058

Alternate gene names: 222525316

Gene position: 2612115-2613407 (Clockwise)

Preceding gene: 222525315

Following gene: 222525320

Centisome position: 49.58

GC content: 57.23

Gene sequence:

>1293_bases
ATGGATCATTTTGTGATTGAAGGTGGTCATCGGCTATCAGGGTCAATTCGACCGGCCGGCAACAAGAATGCTGCGCTACC
ATTGCTTGCGGCCAGTCTGTTGACCAGTGAGCCTGTAACGTTGCGGAATATTCCTGATATTGGAGATGTCCGTACCAAGC
TGGCACTCCTGGCACATCTCGGTGTGTATGTTGATCGGCCAGAGGCAAATGTTGTCCATCTGCGCGCCGATCAACTGGTA
GCGGGTGAACCTGACACCACCCTGGCCAGGCGCATCCGTACCTCGCCGCTGCTCGCCGGCCCCCTACTGGCCCGGCGGGG
ATATGTCACGCTGCCACGTCCTGGCGGCGATGCCATTGGCAGACGCCGGCTCGACACGCATCTGTTAGCACTTCAGGCGT
TGGGGGTTCACGTAGAAGTTACTCCCACCAGCTATATTCTGACGACGAATGGCCTGCGTGGGGCCGACATTTTTCTGGAT
GAGATGAGTGTCACCGGTACCGAACAGGCAATTATTGCGGCCTGTGTTGCCGAAGGGCATACCACCATTGCGAATGCCGC
CTCTGAACCACACGTCCAGGACCTGTGCCACTTTTTGAATCGTATGGGCGCACGGATCAGCGGCATCGGCACCAATCTGC
TTGAGATTGAGGGAGTAACCAGCCTGCACGGTGCCGATTACACGATTGGCCCTGATTTCATGGAGGTGGGTTCGCTGATT
GGCCTGGCTGCCGTGACCCGTAGTGAATTGCGGATTGTTGGTGCCCGTCCACGCGAGCATCGCATGACCAAAATTATGTT
TGGCCGGTTAGGAGTTACCTGGCACGAGGAAGGTGAGGATATTGTTGTCCCAGCCGATCAAGAGCTGGTGGTGCGTCACG
ATCTGCACGGTGCAATCCCGAAGATCGACTCGGCGCCGTGGCCCGGCTTCAACCCGGATTTGATCAGTACGGCGATTGTT
GTGGCAACGCAGGCGCGTGGTACTGTGCTCATTCACGAAAAGATGTTTGAAAGTCGACTCTTCTTTGTTGACCGGTTAAT
TGGCATGGGAGCGCGCATTGTGCTCTGTGATCCGCATCGGGCAGTGGTGGTCGGGCCATCGCAACTGTACGGCGAACCTG
ATGGCTTGCCCAGCCCTGATATTCGGGCAGGTATGGCATTGGTGACAGCGGCCTTGTGTGCCAAAGGGCGTAGCGTCATC
TACAACATTGGGCAGATTGATCGTGGCTACGAGCGGATTGAAGAGCGGTTAGCAGCGCTGGGCGCACGGATCGAGCGGGT
GCGGGCTTCGTAG

Upstream 100 bases:

>100_bases
GGCGCCACTTGCCCGCCGGGCAGAATGGTTCTCTGCTCACGGGCAAGGCGATCTTGTTTGGATGCACGCAGTCGATTCTT
TGAAGTCGAGGAATACAAAC

Downstream 100 bases:

>100_bases
AGTTTCTACCCGCCTTCAGCGAGCAAAAGTCCTCTCTGACCGAATCTTGAGCGATACAGTGCATCACTGCCTGTCATCGG
ATATGCGGTGAACCATGACC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MDHFVIEGGHRLSGSIRPAGNKNAALPLLAASLLTSEPVTLRNIPDIGDVRTKLALLAHLGVYVDRPEANVVHLRADQLV
AGEPDTTLARRIRTSPLLAGPLLARRGYVTLPRPGGDAIGRRRLDTHLLALQALGVHVEVTPTSYILTTNGLRGADIFLD
EMSVTGTEQAIIAACVAEGHTTIANAASEPHVQDLCHFLNRMGARISGIGTNLLEIEGVTSLHGADYTIGPDFMEVGSLI
GLAAVTRSELRIVGARPREHRMTKIMFGRLGVTWHEEGEDIVVPADQELVVRHDLHGAIPKIDSAPWPGFNPDLISTAIV
VATQARGTVLIHEKMFESRLFFVDRLIGMGARIVLCDPHRAVVVGPSQLYGEPDGLPSPDIRAGMALVTAALCAKGRSVI
YNIGQIDRGYERIEERLAALGARIERVRAS

Sequences:

>Translated_430_residues
MDHFVIEGGHRLSGSIRPAGNKNAALPLLAASLLTSEPVTLRNIPDIGDVRTKLALLAHLGVYVDRPEANVVHLRADQLV
AGEPDTTLARRIRTSPLLAGPLLARRGYVTLPRPGGDAIGRRRLDTHLLALQALGVHVEVTPTSYILTTNGLRGADIFLD
EMSVTGTEQAIIAACVAEGHTTIANAASEPHVQDLCHFLNRMGARISGIGTNLLEIEGVTSLHGADYTIGPDFMEVGSLI
GLAAVTRSELRIVGARPREHRMTKIMFGRLGVTWHEEGEDIVVPADQELVVRHDLHGAIPKIDSAPWPGFNPDLISTAIV
VATQARGTVLIHEKMFESRLFFVDRLIGMGARIVLCDPHRAVVVGPSQLYGEPDGLPSPDIRAGMALVTAALCAKGRSVI
YNIGQIDRGYERIEERLAALGARIERVRAS
>Mature_430_residues
MDHFVIEGGHRLSGSIRPAGNKNAALPLLAASLLTSEPVTLRNIPDIGDVRTKLALLAHLGVYVDRPEANVVHLRADQLV
AGEPDTTLARRIRTSPLLAGPLLARRGYVTLPRPGGDAIGRRRLDTHLLALQALGVHVEVTPTSYILTTNGLRGADIFLD
EMSVTGTEQAIIAACVAEGHTTIANAASEPHVQDLCHFLNRMGARISGIGTNLLEIEGVTSLHGADYTIGPDFMEVGSLI
GLAAVTRSELRIVGARPREHRMTKIMFGRLGVTWHEEGEDIVVPADQELVVRHDLHGAIPKIDSAPWPGFNPDLISTAIV
VATQARGTVLIHEKMFESRLFFVDRLIGMGARIVLCDPHRAVVVGPSQLYGEPDGLPSPDIRAGMALVTAALCAKGRSVI
YNIGQIDRGYERIEERLAALGARIERVRAS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=432, Percent_Identity=37.2685185185185, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46306; Mature: 46306

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHFVIEGGHRLSGSIRPAGNKNAALPLLAASLLTSEPVTLRNIPDIGDVRTKLALLAHL
CCCEEEECCCEECCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHH
GVYVDRPEANVVHLRADQLVAGEPDTTLARRIRTSPLLAGPLLARRGYVTLPRPGGDAIG
CEEEECCCCCEEEEECCCEECCCCCHHHHHHHHCCCCHHHHHHHCCCEEEECCCCCHHHH
RRRLDTHLLALQALGVHVEVTPTSYILTTNGLRGADIFLDEMSVTGTEQAIIAACVAEGH
HHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHCCC
TTIANAASEPHVQDLCHFLNRMGARISGIGTNLLEIEGVTSLHGADYTIGPDFMEVGSLI
CHHHCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEECCCCEECCCCCCCCCCHHHHHHHH
GLAAVTRSELRIVGARPREHRMTKIMFGRLGVTWHEEGEDIVVPADQELVVRHDLHGAIP
HHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCEECCCCCEEEECCCCCEEEEECCCCCCC
KIDSAPWPGFNPDLISTAIVVATQARGTVLIHEKMFESRLFFVDRLIGMGARIVLCDPHR
CCCCCCCCCCCHHHHHHEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCC
AVVVGPSQLYGEPDGLPSPDIRAGMALVTAALCAKGRSVIYNIGQIDRGYERIEERLAAL
EEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
GARIERVRAS
HHHHHHHCCC
>Mature Secondary Structure
MDHFVIEGGHRLSGSIRPAGNKNAALPLLAASLLTSEPVTLRNIPDIGDVRTKLALLAHL
CCCEEEECCCEECCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHH
GVYVDRPEANVVHLRADQLVAGEPDTTLARRIRTSPLLAGPLLARRGYVTLPRPGGDAIG
CEEEECCCCCEEEEECCCEECCCCCHHHHHHHHCCCCHHHHHHHCCCEEEECCCCCHHHH
RRRLDTHLLALQALGVHVEVTPTSYILTTNGLRGADIFLDEMSVTGTEQAIIAACVAEGH
HHHHHHHHHHHHHHCEEEEECCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHCCC
TTIANAASEPHVQDLCHFLNRMGARISGIGTNLLEIEGVTSLHGADYTIGPDFMEVGSLI
CHHHCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEECCCCEECCCCCCCCCCHHHHHHHH
GLAAVTRSELRIVGARPREHRMTKIMFGRLGVTWHEEGEDIVVPADQELVVRHDLHGAIP
HHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCEECCCCCEEEECCCCCEEEEECCCCCCC
KIDSAPWPGFNPDLISTAIVVATQARGTVLIHEKMFESRLFFVDRLIGMGARIVLCDPHR
CCCCCCCCCCCHHHHHHEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCC
AVVVGPSQLYGEPDGLPSPDIRAGMALVTAALCAKGRSVIYNIGQIDRGYERIEERLAAL
EEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
GARIERVRAS
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA