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The map label for this gene is coaE [H]

Identifier: 222525313

GI number: 222525313

Start: 2606817

End: 2607473

Strand: Reverse

Name: coaE [H]

Synonym: Chy400_2055

Alternate gene names: 222525313

Gene position: 2607473-2606817 (Counterclockwise)

Preceding gene: 222525314

Following gene: 222525311

Centisome position: 49.49

GC content: 60.43

Gene sequence:

>657_bases
ATGAAGCATCCCGGCATCTTTCTGATCGGTCTGACCGGCGGTATCGCCTGTGGCAAGAGCACTGTTCTGGCGATGCTGGC
CGCCCTCGGCGCGCGCACTATTGATGCTGATCGGGTAACACACCGTCTGCAACAACCGGGGACACCGGTGTATCAGGCCA
TTGTCGCAGCGTTCGGCCCCCAGATTTTGACCGCACCCGGCGGTGCGATTGATCGCCGTAAGTTAGGGAACATCGTGTTT
AACGACCAGGCGGCACTGAAGAGGTTAGAGTCGATCGTCCATCCGGCAGTACGCACCGAAATACAACGGTTTCTGGCCGA
GGTCGCCAATGCGGGTGGGTATGCCACCCGCCTGCGACCTGTCGAACGTCCGATTGTGGTGATTGATGCAATCAAGCTCA
TCGAGTCGGGCTGGGCTGACGAGTGTGATCAGGTCTGGGTCGTCACCTGCCCGCCTGAACAACAGATTGAGCGCCTGATG
ACAACCCGGGGGATGTCGCTGGCTGAAGCGCAGGCCCGGATCGCCGCACAACCTCCGCAAGAGAGTCGCTTCAGCCGCGC
CCATGTCATTATTGACAACAGCGGTTCGCAAGCGCGTACACGTGCTCAGGTTGAAGCGGCCTGGCAACAGGCTCTGGTCG
CCAGTCACGGCGCGTAG

Upstream 100 bases:

>100_bases
GTGATGCCGAGCGGCGAGCCGAACTGATCAGTGAATTGCTGGAACTGATCGGTATTAGCGATGACGCTCTGGTGTTGCAG
GAATACGTGGAGCTGGTGGC

Downstream 100 bases:

>100_bases
GTCACCTGTCGGCGCTCTTCGATCACGGCCCCATCGGCCAGGGTGACTCGTAGCCGAACGGTATACGTACCGGTTGGCCA
GGCACCGGCATTCCACATCC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKHPGIFLIGLTGGIACGKSTVLAMLAALGARTIDADRVTHRLQQPGTPVYQAIVAAFGPQILTAPGGAIDRRKLGNIVF
NDQAALKRLESIVHPAVRTEIQRFLAEVANAGGYATRLRPVERPIVVIDAIKLIESGWADECDQVWVVTCPPEQQIERLM
TTRGMSLAEAQARIAAQPPQESRFSRAHVIIDNSGSQARTRAQVEAAWQQALVASHGA

Sequences:

>Translated_218_residues
MKHPGIFLIGLTGGIACGKSTVLAMLAALGARTIDADRVTHRLQQPGTPVYQAIVAAFGPQILTAPGGAIDRRKLGNIVF
NDQAALKRLESIVHPAVRTEIQRFLAEVANAGGYATRLRPVERPIVVIDAIKLIESGWADECDQVWVVTCPPEQQIERLM
TTRGMSLAEAQARIAAQPPQESRFSRAHVIIDNSGSQARTRAQVEAAWQQALVASHGA
>Mature_218_residues
MKHPGIFLIGLTGGIACGKSTVLAMLAALGARTIDADRVTHRLQQPGTPVYQAIVAAFGPQILTAPGGAIDRRKLGNIVF
NDQAALKRLESIVHPAVRTEIQRFLAEVANAGGYATRLRPVERPIVVIDAIKLIESGWADECDQVWVVTCPPEQQIERLM
TTRGMSLAEAQARIAAQPPQESRFSRAHVIIDNSGSQARTRAQVEAAWQQALVASHGA

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI110227607, Length=207, Percent_Identity=34.7826086956522, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI110227605, Length=207, Percent_Identity=34.7826086956522, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI110227603, Length=207, Percent_Identity=34.7826086956522, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI110227601, Length=207, Percent_Identity=34.7826086956522, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI205277394, Length=220, Percent_Identity=34.0909090909091, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI191252797, Length=200, Percent_Identity=34, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI191252795, Length=200, Percent_Identity=34, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1786292, Length=190, Percent_Identity=30, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554944, Length=213, Percent_Identity=34.2723004694836, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25143409, Length=207, Percent_Identity=27.0531400966184, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320402, Length=209, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24658602, Length=206, Percent_Identity=36.4077669902913, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24644728, Length=192, Percent_Identity=31.25, Blast_Score=110, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23469; Mature: 23469

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHPGIFLIGLTGGIACGKSTVLAMLAALGARTIDADRVTHRLQQPGTPVYQAIVAAFGP
CCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCC
QILTAPGGAIDRRKLGNIVFNDQAALKRLESIVHPAVRTEIQRFLAEVANAGGYATRLRP
CEEECCCCCCCHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
VERPIVVIDAIKLIESGWADECDQVWVVTCPPEQQIERLMTTRGMSLAEAQARIAAQPPQ
CCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCH
ESRFSRAHVIIDNSGSQARTRAQVEAAWQQALVASHGA
HHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKHPGIFLIGLTGGIACGKSTVLAMLAALGARTIDADRVTHRLQQPGTPVYQAIVAAFGP
CCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCC
QILTAPGGAIDRRKLGNIVFNDQAALKRLESIVHPAVRTEIQRFLAEVANAGGYATRLRP
CEEECCCCCCCHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
VERPIVVIDAIKLIESGWADECDQVWVVTCPPEQQIERLMTTRGMSLAEAQARIAAQPPQ
CCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCH
ESRFSRAHVIIDNSGSQARTRAQVEAAWQQALVASHGA
HHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA