Click here to switch to the map view.

The map label for this gene is ybdL [H]

Identifier: 222525305

GI number: 222525305

Start: 2596023

End: 2597213

Strand: Reverse

Name: ybdL [H]

Synonym: Chy400_2047

Alternate gene names: 222525305

Gene position: 2597213-2596023 (Counterclockwise)

Preceding gene: 222525307

Following gene: 222525304

Centisome position: 49.29

GC content: 58.44

Gene sequence:

>1191_bases
ATGACACTATCACTCAGCGCCGAGCGGGTTCGTCAGTTTGGTACCACGATTTTTGCCGAAATCAGTGCGCTTGCCGTGCA
ATGTGGTGCCGTGAATCTGGGCCAGGGTTTTCCTGATTTCGCCGGGCCGGAATGGGTGAAGCAGGCTGCGATAGAGGCGA
TCACCGCCGATGCCAACCAGTATGCACCCTACATCGGTGTGCCGCGTCTGCGAGAGGCGATTGCGGCAACCTGGCAGGCC
CAGGGCTGGCGGACAGTCGATCCGGTGACTGAAGTGACCGTCACCAGTGGCGCAACTGAGGCATTGTTCGGCGCAGTGCA
GGCACTGGTAAATCCCGGCGATGAGGTTATCCTGTTCGAGCCGTTTTATGATGCGTATTTGCCCGATGTGACGATGGCCG
GCGGTATTCCCCGTTTTGTCCGCCTCCATCCCCCCGGCGATGGTCATGCAACGTGGTGGTTCGATCCGGCAGAGTTGCAG
GCCGCTTTCTCGCCGCGTACCCGTCTGCTGATGCTGAATACACCCCACAATCCAACCGGTAAGGTATTTCGCCGGGACGA
GCTGGAGCAGATCGCCGATCTGTGCCAGACTTACGACGTGATCGTGATTTCTGATGAGGTATACGACCAACTGGTCTTTG
CCGGCGCAACCCATATACCCATCGCGACGCTGCCAGGCATGTGGGAACGGACATTGACCATTAACAGTCTGGGCAAGACC
TTCAGCCTCACCGGTTGGAAAATCGGGTACGCAGTTGGTCCAGCCAGCCTCAACGCCGCCCTGCGCGCCGCGCACCAGTG
GATTACCTTTGCGACCGCGACTCCATTGCAATTTGCCGCCGCGGCTGCCCTGGAAGGAGCTTTGCATAACGGCTATTATG
AACAGTTTCGCGCTGAATATACAGCTCGTTATCGTCTGCTGGAAGAGATTCTGGTCAGTGTCGGCTTTCCAGTCCTGCCA
ACCGAAGGCAGCTATTTCCTGATGGCCGACATTACCCCCACCGGCTTTCACGACGATGTCACGTTCTGTCGCTACCTGAC
GCAGGAGGTTGGCGTTGCTGCTATTCCCCCTTCTGCTTTTTACGCCCGGCAGCACGATTTGCCGCTGCTGGCCCGTTTCT
GTTTTGCCAAGCGTCCTGAGACGCTGCGCGCCGCCCAACAACGGTTGTTGGCCTGGCGACAGCGCAGTTGA

Upstream 100 bases:

>100_bases
TTCGCAAAAGTTGCAGTACTCTGTGGTACCATTAGTAAAGATGCAGGGTTACACTGTAATACGGGCACGCTGTACCTGTA
ACTTCTTCCAGGGGTGCACG

Downstream 100 bases:

>100_bases
GAAAGAGAGAGATGTCATGGAAACCCGTCTCCAAGAACTTCGTGCTCGCCTCCAGGAGATTGACGATCTGAACAGTGCTG
CTGCTGTACTGGGTTGGGAT

Product: class I and II aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTLSLSAERVRQFGTTIFAEISALAVQCGAVNLGQGFPDFAGPEWVKQAAIEAITADANQYAPYIGVPRLREAIAATWQA
QGWRTVDPVTEVTVTSGATEALFGAVQALVNPGDEVILFEPFYDAYLPDVTMAGGIPRFVRLHPPGDGHATWWFDPAELQ
AAFSPRTRLLMLNTPHNPTGKVFRRDELEQIADLCQTYDVIVISDEVYDQLVFAGATHIPIATLPGMWERTLTINSLGKT
FSLTGWKIGYAVGPASLNAALRAAHQWITFATATPLQFAAAAALEGALHNGYYEQFRAEYTARYRLLEEILVSVGFPVLP
TEGSYFLMADITPTGFHDDVTFCRYLTQEVGVAAIPPSAFYARQHDLPLLARFCFAKRPETLRAAQQRLLAWRQRS

Sequences:

>Translated_396_residues
MTLSLSAERVRQFGTTIFAEISALAVQCGAVNLGQGFPDFAGPEWVKQAAIEAITADANQYAPYIGVPRLREAIAATWQA
QGWRTVDPVTEVTVTSGATEALFGAVQALVNPGDEVILFEPFYDAYLPDVTMAGGIPRFVRLHPPGDGHATWWFDPAELQ
AAFSPRTRLLMLNTPHNPTGKVFRRDELEQIADLCQTYDVIVISDEVYDQLVFAGATHIPIATLPGMWERTLTINSLGKT
FSLTGWKIGYAVGPASLNAALRAAHQWITFATATPLQFAAAAALEGALHNGYYEQFRAEYTARYRLLEEILVSVGFPVLP
TEGSYFLMADITPTGFHDDVTFCRYLTQEVGVAAIPPSAFYARQHDLPLLARFCFAKRPETLRAAQQRLLAWRQRS
>Mature_395_residues
TLSLSAERVRQFGTTIFAEISALAVQCGAVNLGQGFPDFAGPEWVKQAAIEAITADANQYAPYIGVPRLREAIAATWQAQ
GWRTVDPVTEVTVTSGATEALFGAVQALVNPGDEVILFEPFYDAYLPDVTMAGGIPRFVRLHPPGDGHATWWFDPAELQA
AFSPRTRLLMLNTPHNPTGKVFRRDELEQIADLCQTYDVIVISDEVYDQLVFAGATHIPIATLPGMWERTLTINSLGKTF
SLTGWKIGYAVGPASLNAALRAAHQWITFATATPLQFAAAAALEGALHNGYYEQFRAEYTARYRLLEEILVSVGFPVLPT
EGSYFLMADITPTGFHDDVTFCRYLTQEVGVAAIPPSAFYARQHDLPLLARFCFAKRPETLRAAQQRLLAWRQRS

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=410, Percent_Identity=40, Blast_Score=298, Evalue=8e-81,
Organism=Homo sapiens, GI56713256, Length=416, Percent_Identity=39.9038461538462, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI95147551, Length=421, Percent_Identity=41.8052256532066, Blast_Score=292, Evalue=4e-79,
Organism=Homo sapiens, GI169881279, Length=421, Percent_Identity=41.8052256532066, Blast_Score=292, Evalue=4e-79,
Organism=Homo sapiens, GI169881281, Length=421, Percent_Identity=36.8171021377672, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI4507369, Length=350, Percent_Identity=26.2857142857143, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1786816, Length=381, Percent_Identity=42.5196850393701, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=28.6821705426357, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788627, Length=340, Percent_Identity=27.9411764705882, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787909, Length=257, Percent_Identity=27.6264591439689, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787710, Length=248, Percent_Identity=27.8225806451613, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=414, Percent_Identity=38.4057971014493, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71994476, Length=414, Percent_Identity=38.4057971014493, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17567369, Length=409, Percent_Identity=33.2518337408313, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17567663, Length=346, Percent_Identity=25.1445086705202, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=386, Percent_Identity=36.2694300518135, Blast_Score=246, Evalue=5e-66,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=40.5339805825243, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=40.5339805825243, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=40.5339805825243, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=40.5339805825243, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI18859735, Length=343, Percent_Identity=23.6151603498542, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43632; Mature: 43501

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSLSAERVRQFGTTIFAEISALAVQCGAVNLGQGFPDFAGPEWVKQAAIEAITADANQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHCCHHH
YAPYIGVPRLREAIAATWQAQGWRTVDPVTEVTVTSGATEALFGAVQALVNPGDEVILFE
CCCCCCCHHHHHHHHHHHHCCCCEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEC
PFYDAYLPDVTMAGGIPRFVRLHPPGDGHATWWFDPAELQAAFSPRTRLLMLNTPHNPTG
CCHHHHCCCCHHCCCCCCEEEECCCCCCCEEEEECHHHHHHHCCCCEEEEEEECCCCCCC
KVFRRDELEQIADLCQTYDVIVISDEVYDQLVFAGATHIPIATLPGMWERTLTINSLGKT
CCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEECCCCE
FSLTGWKIGYAVGPASLNAALRAAHQWITFATATPLQFAAAAALEGALHNGYYEQFRAEY
EEECCEEEEEEECHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHH
TARYRLLEEILVSVGFPVLPTEGSYFLMADITPTGFHDDVTFCRYLTQEVGVAAIPPSAF
HHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEECCCHHH
YARQHDLPLLARFCFAKRPETLRAAQQRLLAWRQRS
HHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLSLSAERVRQFGTTIFAEISALAVQCGAVNLGQGFPDFAGPEWVKQAAIEAITADANQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHCCHHH
YAPYIGVPRLREAIAATWQAQGWRTVDPVTEVTVTSGATEALFGAVQALVNPGDEVILFE
CCCCCCCHHHHHHHHHHHHCCCCEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEC
PFYDAYLPDVTMAGGIPRFVRLHPPGDGHATWWFDPAELQAAFSPRTRLLMLNTPHNPTG
CCHHHHCCCCHHCCCCCCEEEECCCCCCCEEEEECHHHHHHHCCCCEEEEEEECCCCCCC
KVFRRDELEQIADLCQTYDVIVISDEVYDQLVFAGATHIPIATLPGMWERTLTINSLGKT
CCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEECCCCE
FSLTGWKIGYAVGPASLNAALRAAHQWITFATATPLQFAAAAALEGALHNGYYEQFRAEY
EEECCEEEEEEECHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHH
TARYRLLEEILVSVGFPVLPTEGSYFLMADITPTGFHDDVTFCRYLTQEVGVAAIPPSAF
HHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEECCCHHH
YARQHDLPLLARFCFAKRPETLRAAQQRLLAWRQRS
HHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]