| Definition | Chloroflexus sp. Y-400-fl chromosome, complete genome. |
|---|---|
| Accession | NC_012032 |
| Length | 5,268,950 |
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The map label for this gene is alr2 [H]
Identifier: 222525202
GI number: 222525202
Start: 2464245
End: 2466695
Strand: Reverse
Name: alr2 [H]
Synonym: Chy400_1942
Alternate gene names: 222525202
Gene position: 2466695-2464245 (Counterclockwise)
Preceding gene: 222525207
Following gene: 222525201
Centisome position: 46.82
GC content: 64.55
Gene sequence:
>2451_bases ATGGATATTCAACTCGCCGAACTTATTGAAGCTGGTGGCACGGTGATCGGGCCGATCCACGCCGATACCTTTACCGATTG GAGCTACGACTCGCGGCTGACTGTGGCCGGTGAGTGTTTTATCGCGCTGCGCACCACACGGGCCGACGGTCACGACTATA TTCCGGCGGCGCTGGCCGCCGGTGCCCGCGGTATTCTGTGTACGCGACCACCGCACGACGCCGGTACGGCCACGGTTGTC GTTTGCCCCGACCCCCAGGCTTTGTTGTTGCGCTGGGCCAGCAATCGCTTGCAGCGGTTGCAACCCACCGTCATTGCCGT GACGGGTGGTATCGGGAAAACGCTGGCCCGGCGGGCCATTGCCGCTGTGCTGGCGACCCACGCTCCCACGTTTCAAAGCC GGCGCAATTTCAATTCTCTGCTGGGGCTGCCGATTGCCCTGGCCCGCCTTGAGCGTGATCACCAGTATGCGGTGCTCGAA TTTGCCGGCGAACATCTGCCCCCGCTGGCAGCGGCTTTCCCACCCCGGCTTGCAGTCGTGACCGCCGGAACCGATGATGC CACAGCGAGATTTCTGGCTCGCCAGGGAGTGACCGTTATTGCCGCCGAAGGCGTATCGTCGGCTCATCTGACCTTCGGCA CAGGGAGTGGGTGTGCCATCCGTGCTACGGCTATCTCCTACCGTCGGGATGGCGTTGATTGTGTGGTGATCGGCCAGGGG CTTGAGCTGCCGATCACCATCCCCTTACCTGGCCCACCCGGTGTAGCCGCTGCCCTGGCCGCCGTTGCCGTTGGTCTGCA CTACGGGGTGAGACCGGCAGCGATCCGCCAGGCCCTGGCCGGTCTGGATGCGCCGGCGGGCCGGCTTCGTCCGCTGCCGG GGGCCAATGGCGAGCTGATTCTGGACGATAGTTTCAATGCGACACCGGAAGCGATGAGGGCAGCCTTGCAGACGCTGGCG GCCATCCCGACCGGACGCCGGATTGCTGTTCTGGGAACACCAACCGAATTGCCGGCAGTTGATGCCACGCCCCTGCTCAC CGAACTGGGTATGCAGGCAGCCCGCAGCGCTGAGTATCTGGTACTGAAGGGCATGGGAGCCGCCACAATGGCTCAGGCCG CCCGGCTGGCTAATCCAACGGTGACCATTCACGTCGTAGACACCAACGAGGCGATTCGGGCAGCGCTGCCACCTTCGCGC AACGATCAGGATGTCGTACTGGTGTCGGGGGGTGCCGGCGAACGCCTCGAACAGGTGGTAGCCCCGTTGCTGGCCCCCGG CTGGCCGCCAGAACAATATCTGGTACGCCAGGAACCGGCGTGGCGTAGTGTGCGGATCGGTGATCCGGGACGACCGACCT GGGTGCATCTCGACCTGACCGCGATTGCCGATAATGTGCGTGCGTTGCGCAACCATGCTGGTGTCCCGCTTATGGTCGTG CTCAAGGGTGATGGCTACGGCCACGGGGCTGCGCGGGTAGCCCGGGCCGCACTACAGGCCGGTGCCGAGATGCTGGCGGT GGCGACGCTCGGTGAAGGCCGGGCACTGCGTGCGCAAGGGATTGCGGCGCCCATCCTGGTCTTGGGCTACACACCACCCT GGCAGGCAGCCGAGGCGATTCGACTCGATCTGATGCTGACCCTCTTCGACGATGATACGGCCCAGGCCCTGCACGCCGCC GCCCTCGAATGCGGTCGTCCCGCCCGGGTGCATGTGAAAGTTGATACCGGTATGGCCCGGTTAGGTTTATCGCCCGCTGA AGTCGCCCCGTTTTTATCCCGGCTACGGGAATTACCCGGCATTGAACCGGTTGCCCTCTACACCCATTTTGCCCGCGCCG ACGAAGCCGATCCGACGCCAACCGAACAACAGTTGGCCCGCTTTCAGGCGGTGCTGGCCGATCTAACTGCCGCCGGCCTG CGTCCGCCGTGCGTTCACGCTGCCAACAGCGCAGCCACCTTGCGCTTTCCGGCGACACACTTCGATATGGTGCGCCCCGG CCTGGCCTGTTATGGGCTGGCGCCGGGTGCGGCTGCTCCACTCCTGCCCGGTATGCGCCCGGCATTGAGCTTCTACACCG AAGTAGCCCAGGTCAAGGATCATCCAGCCGGTACTCCCATCTCCTACGGCGGTACCTTCGTCACCGCGCGACCGTCGCGC ATCGCGACGATTCCGGTTGGCTATGCCGATGGTTTGCGGCGCTCACCACCGTGGCGGGAAGTGCTGATTCGGGGGCAGCG CGCCCCAATTGTCGGACGCATTTGTATGGATTACGCAATGGTGGATGTGACCGACATTCCCGGTGTCCGGCGCGGCGATG CGGTCACGATTATCGGGCGGCAGGGTGATGCCGTGATCGGGGTTGATGAGATCGCCGGCTGGCTGGGCACGATCAGCTAC GAAGTGCTGACCGGTATCCTACCCCGCGTACCCCGCGAGATTGGGCCGTAG
Upstream 100 bases:
>100_bases CAACATCCCACTCATCCACACCTGCGCGACTGCGCCGGTGGTATGCTTTGATACGAAGCATTGCCATCTGGCCTGTCTTG CAGCCAATCAGGATACACCG
Downstream 100 bases:
>100_bases CGATAATCAGATCGGTCAGATCCGTGTACAATGACAATCAACAGCAGCCACATGGCGTAGTAAGGAGCGATCTATGCTTA CCCCGTTTCAAAATGAACCC
Product: alanine racemase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 816; Mature: 816
Protein sequence:
>816_residues MDIQLAELIEAGGTVIGPIHADTFTDWSYDSRLTVAGECFIALRTTRADGHDYIPAALAAGARGILCTRPPHDAGTATVV VCPDPQALLLRWASNRLQRLQPTVIAVTGGIGKTLARRAIAAVLATHAPTFQSRRNFNSLLGLPIALARLERDHQYAVLE FAGEHLPPLAAAFPPRLAVVTAGTDDATARFLARQGVTVIAAEGVSSAHLTFGTGSGCAIRATAISYRRDGVDCVVIGQG LELPITIPLPGPPGVAAALAAVAVGLHYGVRPAAIRQALAGLDAPAGRLRPLPGANGELILDDSFNATPEAMRAALQTLA AIPTGRRIAVLGTPTELPAVDATPLLTELGMQAARSAEYLVLKGMGAATMAQAARLANPTVTIHVVDTNEAIRAALPPSR NDQDVVLVSGGAGERLEQVVAPLLAPGWPPEQYLVRQEPAWRSVRIGDPGRPTWVHLDLTAIADNVRALRNHAGVPLMVV LKGDGYGHGAARVARAALQAGAEMLAVATLGEGRALRAQGIAAPILVLGYTPPWQAAEAIRLDLMLTLFDDDTAQALHAA ALECGRPARVHVKVDTGMARLGLSPAEVAPFLSRLRELPGIEPVALYTHFARADEADPTPTEQQLARFQAVLADLTAAGL RPPCVHAANSAATLRFPATHFDMVRPGLACYGLAPGAAAPLLPGMRPALSFYTEVAQVKDHPAGTPISYGGTFVTARPSR IATIPVGYADGLRRSPPWREVLIRGQRAPIVGRICMDYAMVDVTDIPGVRRGDAVTIIGRQGDAVIGVDEIAGWLGTISY EVLTGILPRVPREIGP
Sequences:
>Translated_816_residues MDIQLAELIEAGGTVIGPIHADTFTDWSYDSRLTVAGECFIALRTTRADGHDYIPAALAAGARGILCTRPPHDAGTATVV VCPDPQALLLRWASNRLQRLQPTVIAVTGGIGKTLARRAIAAVLATHAPTFQSRRNFNSLLGLPIALARLERDHQYAVLE FAGEHLPPLAAAFPPRLAVVTAGTDDATARFLARQGVTVIAAEGVSSAHLTFGTGSGCAIRATAISYRRDGVDCVVIGQG LELPITIPLPGPPGVAAALAAVAVGLHYGVRPAAIRQALAGLDAPAGRLRPLPGANGELILDDSFNATPEAMRAALQTLA AIPTGRRIAVLGTPTELPAVDATPLLTELGMQAARSAEYLVLKGMGAATMAQAARLANPTVTIHVVDTNEAIRAALPPSR NDQDVVLVSGGAGERLEQVVAPLLAPGWPPEQYLVRQEPAWRSVRIGDPGRPTWVHLDLTAIADNVRALRNHAGVPLMVV LKGDGYGHGAARVARAALQAGAEMLAVATLGEGRALRAQGIAAPILVLGYTPPWQAAEAIRLDLMLTLFDDDTAQALHAA ALECGRPARVHVKVDTGMARLGLSPAEVAPFLSRLRELPGIEPVALYTHFARADEADPTPTEQQLARFQAVLADLTAAGL RPPCVHAANSAATLRFPATHFDMVRPGLACYGLAPGAAAPLLPGMRPALSFYTEVAQVKDHPAGTPISYGGTFVTARPSR IATIPVGYADGLRRSPPWREVLIRGQRAPIVGRICMDYAMVDVTDIPGVRRGDAVTIIGRQGDAVIGVDEIAGWLGTISY EVLTGILPRVPREIGP >Mature_816_residues MDIQLAELIEAGGTVIGPIHADTFTDWSYDSRLTVAGECFIALRTTRADGHDYIPAALAAGARGILCTRPPHDAGTATVV VCPDPQALLLRWASNRLQRLQPTVIAVTGGIGKTLARRAIAAVLATHAPTFQSRRNFNSLLGLPIALARLERDHQYAVLE FAGEHLPPLAAAFPPRLAVVTAGTDDATARFLARQGVTVIAAEGVSSAHLTFGTGSGCAIRATAISYRRDGVDCVVIGQG LELPITIPLPGPPGVAAALAAVAVGLHYGVRPAAIRQALAGLDAPAGRLRPLPGANGELILDDSFNATPEAMRAALQTLA AIPTGRRIAVLGTPTELPAVDATPLLTELGMQAARSAEYLVLKGMGAATMAQAARLANPTVTIHVVDTNEAIRAALPPSR NDQDVVLVSGGAGERLEQVVAPLLAPGWPPEQYLVRQEPAWRSVRIGDPGRPTWVHLDLTAIADNVRALRNHAGVPLMVV LKGDGYGHGAARVARAALQAGAEMLAVATLGEGRALRAQGIAAPILVLGYTPPWQAAEAIRLDLMLTLFDDDTAQALHAA ALECGRPARVHVKVDTGMARLGLSPAEVAPFLSRLRELPGIEPVALYTHFARADEADPTPTEQQLARFQAVLADLTAAGL RPPCVHAANSAATLRFPATHFDMVRPGLACYGLAPGAAAPLLPGMRPALSFYTEVAQVKDHPAGTPISYGGTFVTARPSR IATIPVGYADGLRRSPPWREVLIRGQRAPIVGRICMDYAMVDVTDIPGVRRGDAVTIIGRQGDAVIGVDEIAGWLGTISY EVLTGILPRVPREIGP
Specific function: Provides the D-alanine required for cell wall biosynthesis [H]
COG id: COG0787
COG function: function code M; Alanine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the alanine racemase family [H]
Homologues:
Organism=Escherichia coli, GI1790487, Length=364, Percent_Identity=34.6153846153846, Blast_Score=173, Evalue=4e-44, Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=32.520325203252, Blast_Score=157, Evalue=2e-39, Organism=Escherichia coli, GI1786274, Length=431, Percent_Identity=28.7703016241299, Blast_Score=107, Evalue=4e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000821 - InterPro: IPR009006 - InterPro: IPR011079 - InterPro: IPR001608 - InterPro: IPR020622 [H]
Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]
EC number: =5.1.1.1 [H]
Molecular weight: Translated: 85605; Mature: 85605
Theoretical pI: Translated: 7.45; Mature: 7.45
Prosite motif: PS00395 ALANINE_RACEMASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDIQLAELIEAGGTVIGPIHADTFTDWSYDSRLTVAGECFIALRTTRADGHDYIPAALAA CCCCHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECEEEEEEEEECCCCCCCCHHHHHC GARGILCTRPPHDAGTATVVVCPDPQALLLRWASNRLQRLQPTVIAVTGGIGKTLARRAI CCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHH AAVLATHAPTFQSRRNFNSLLGLPIALARLERDHQYAVLEFAGEHLPPLAAAFPPRLAVV HHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHCCCCCEEEE TAGTDDATARFLARQGVTVIAAEGVSSAHLTFGTGSGCAIRATAISYRRDGVDCVVIGQG ECCCCHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCEEEEEEEECCCCCCCEEEECCC LELPITIPLPGPPGVAAALAAVAVGLHYGVRPAAIRQALAGLDAPAGRLRPLPGANGELI CCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEE LDDSFNATPEAMRAALQTLAAIPTGRRIAVLGTPTELPAVDATPLLTELGMQAARSAEYL ECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEE VLKGMGAATMAQAARLANPTVTIHVVDTNEAIRAALPPSRNDQDVVLVSGGAGERLEQVV EEECCCHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCCCEEEEEECCCHHHHHHHH APLLAPGWPPEQYLVRQEPAWRSVRIGDPGRPTWVHLDLTAIADNVRALRNHAGVPLMVV HHHHCCCCCCHHHHCCCCCCCCEEEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEE LKGDGYGHGAARVARAALQAGAEMLAVATLGEGRALRAQGIAAPILVLGYTPPWQAAEAI EECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCEEEEECCCCHHHHHHE RLDLMLTLFDDDTAQALHAAALECGRPARVHVKVDTGMARLGLSPAEVAPFLSRLRELPG EEEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHCCCHHHHHHHHHHHHHCCC IEPVALYTHFARADEADPTPTEQQLARFQAVLADLTAAGLRPPCVHAANSAATLRFPATH CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCHH FDMVRPGLACYGLAPGAAAPLLPGMRPALSFYTEVAQVKDHPAGTPISYGGTFVTARPSR HHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCE IATIPVGYADGLRRSPPWREVLIRGQRAPIVGRICMDYAMVDVTDIPGVRRGDAVTIIGR EEEEECCHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCEEEEEEC QGDAVIGVDEIAGWLGTISYEVLTGILPRVPREIGP CCCEEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHCC >Mature Secondary Structure MDIQLAELIEAGGTVIGPIHADTFTDWSYDSRLTVAGECFIALRTTRADGHDYIPAALAA CCCCHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECEEEEEEEEECCCCCCCCHHHHHC GARGILCTRPPHDAGTATVVVCPDPQALLLRWASNRLQRLQPTVIAVTGGIGKTLARRAI CCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHH AAVLATHAPTFQSRRNFNSLLGLPIALARLERDHQYAVLEFAGEHLPPLAAAFPPRLAVV HHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHCCCCCEEEE TAGTDDATARFLARQGVTVIAAEGVSSAHLTFGTGSGCAIRATAISYRRDGVDCVVIGQG ECCCCHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCEEEEEEEECCCCCCCEEEECCC LELPITIPLPGPPGVAAALAAVAVGLHYGVRPAAIRQALAGLDAPAGRLRPLPGANGELI CCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEE LDDSFNATPEAMRAALQTLAAIPTGRRIAVLGTPTELPAVDATPLLTELGMQAARSAEYL ECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEE VLKGMGAATMAQAARLANPTVTIHVVDTNEAIRAALPPSRNDQDVVLVSGGAGERLEQVV EEECCCHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCCCEEEEEECCCHHHHHHHH APLLAPGWPPEQYLVRQEPAWRSVRIGDPGRPTWVHLDLTAIADNVRALRNHAGVPLMVV HHHHCCCCCCHHHHCCCCCCCCEEEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEE LKGDGYGHGAARVARAALQAGAEMLAVATLGEGRALRAQGIAAPILVLGYTPPWQAAEAI EECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCEEEEECCCCHHHHHHE RLDLMLTLFDDDTAQALHAAALECGRPARVHVKVDTGMARLGLSPAEVAPFLSRLRELPG EEEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHCCCHHHHHHHHHHHHHCCC IEPVALYTHFARADEADPTPTEQQLARFQAVLADLTAAGLRPPCVHAANSAATLRFPATH CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCHH FDMVRPGLACYGLAPGAAAPLLPGMRPALSFYTEVAQVKDHPAGTPISYGGTFVTARPSR HHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCE IATIPVGYADGLRRSPPWREVLIRGQRAPIVGRICMDYAMVDVTDIPGVRRGDAVTIIGR EEEEECCHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCEEEEEEC QGDAVIGVDEIAGWLGTISYEVLTGILPRVPREIGP CCCEEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11997336 [H]