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The map label for this gene is 222525196

Identifier: 222525196

GI number: 222525196

Start: 2456326

End: 2457678

Strand: Reverse

Name: 222525196

Synonym: Chy400_1936

Alternate gene names: NA

Gene position: 2457678-2456326 (Counterclockwise)

Preceding gene: 222525197

Following gene: 222525195

Centisome position: 46.64

GC content: 59.72

Gene sequence:

>1353_bases
ATGAGTCTGGAAAACCTCTACAACGACCGTCGGGAAGCGGCACTGGCCGATTTCAATCGGGCAATCGCCATTGACGAAAA
CTATGCCTGGGCCTACTTTCAGCGCGGGCAAGTACTGCGCGAACTGGGACGTCTCGAAGAGTCGCTGGACGACTTAACGC
GAGCCTGTGACCTCGAACCCGACGATCCGGCGTATCACGCCGAACGCGGCGAGACGCTCCGCATGTTACGGCGGCATGAA
GCGGCCATCGAGGCCTTCTCACGCGCCATTGCCCTCCGTCCAGAATACCCCTGGGCATTAGGCAGTCGTGGTCAGGTCTG
GCGAGCCTTGCGGCGCCATCACGAAGCCCTGGTCGACTTCGATGCTGCCCTGGCGCTCAATCCCAATCTGGCGTGGATCC
ACGCCGAACGGGGCGAGTCACTGCGGGCGCTCAATCAGCATCAGGAAGCAATAGAAGCCTTTAGTCGGGCGTTAGCCATC
GATCCGGCCTACCCCTGGGCATTGGGACATCGGGGGATCACCTATCGCGAGATGCGCGATTTCCCGGCAGCTATCGCCGA
TTTCGACGCCGCCATTGCCTTGCAGGGCAACATGGCCTGGCTCTACGCCGAGCGTGGTGAAACCCGTCGGCTGGCCGATG
ACTTTGAGGGTGCCCTTGCCGACCTGAGCCGGGCGCTGGAACTTGATTCCGCTTACGCCTGGGCATTTGGTAGTCGCGGA
GCCGCGTTTCGCGCCGTCGGCGATCTCAACGCAGCGTTGGCCGATTTCAATCGAGCGCTGGAATTAGATCCAGGCTACAC
CTGGGTCTACTTTCAGCGTGGTCTCCTCCACCGTAACACCAATCGTACCGACGAGGCAATTGCTGACTTCAGCCGTGCTA
TCGAACTGGAACCGAACTATATAGCTGCCCTGGCCGAACGCGGTGAACTGTTCCGTTTGCAGCGTCGTTACGAAGAAGCC
CTGCGGGACTTCAACCGCACCATCGAACTCCAACCCGATCACGCCTGGGCATTGGGTAGTCGCGGCCAGGTCTATCGCGT
GCTGGCTCGTTACGACGAAGCCCTGGCCGACTTCAACCGTGCGCTGGCCCTGAAGCCAGATATGGTATGGGTGATTGCTG
AACGGGGGGAAACCCACCGCCTGCTCCGCAACTACAACGAGGCGCTGGAAGATTTTAATCGTGCGCTTGAACTATCACCC
AACGATTCGTGGGTACTCAGCCGGCGAGGTGCAACCTATCAGTCACTGAAAATCTACGAAGAGGCGTACATCGATCTGAC
CAGGGCGATTGAAATTGATCCAAACAACGCCTGGGCCTGGGCCCAGCGCGGCTCACTCTTCCGCCAGATGTAG

Upstream 100 bases:

>100_bases
CGCCGCGGTTGATGGCGGCACAGGGTGTAACAATTCTTCACGTTGTTTCGTACTATGTCATAGCCTTTGTATTGGCATAT
CTACGCTGAAAGGGGGGGCC

Downstream 100 bases:

>100_bases
AATGGCGCAGCGCAGGACTGCACAGGAGAGGGCGGGCAACATCCCGCCCTCGGTAGTCGAATGACCCACTCGCATCCCCA
AAACCGGGAGAACCGTGGAT

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSLENLYNDRREAALADFNRAIAIDENYAWAYFQRGQVLRELGRLEESLDDLTRACDLEPDDPAYHAERGETLRMLRRHE
AAIEAFSRAIALRPEYPWALGSRGQVWRALRRHHEALVDFDAALALNPNLAWIHAERGESLRALNQHQEAIEAFSRALAI
DPAYPWALGHRGITYREMRDFPAAIADFDAAIALQGNMAWLYAERGETRRLADDFEGALADLSRALELDSAYAWAFGSRG
AAFRAVGDLNAALADFNRALELDPGYTWVYFQRGLLHRNTNRTDEAIADFSRAIELEPNYIAALAERGELFRLQRRYEEA
LRDFNRTIELQPDHAWALGSRGQVYRVLARYDEALADFNRALALKPDMVWVIAERGETHRLLRNYNEALEDFNRALELSP
NDSWVLSRRGATYQSLKIYEEAYIDLTRAIEIDPNNAWAWAQRGSLFRQM

Sequences:

>Translated_450_residues
MSLENLYNDRREAALADFNRAIAIDENYAWAYFQRGQVLRELGRLEESLDDLTRACDLEPDDPAYHAERGETLRMLRRHE
AAIEAFSRAIALRPEYPWALGSRGQVWRALRRHHEALVDFDAALALNPNLAWIHAERGESLRALNQHQEAIEAFSRALAI
DPAYPWALGHRGITYREMRDFPAAIADFDAAIALQGNMAWLYAERGETRRLADDFEGALADLSRALELDSAYAWAFGSRG
AAFRAVGDLNAALADFNRALELDPGYTWVYFQRGLLHRNTNRTDEAIADFSRAIELEPNYIAALAERGELFRLQRRYEEA
LRDFNRTIELQPDHAWALGSRGQVYRVLARYDEALADFNRALALKPDMVWVIAERGETHRLLRNYNEALEDFNRALELSP
NDSWVLSRRGATYQSLKIYEEAYIDLTRAIEIDPNNAWAWAQRGSLFRQM
>Mature_449_residues
SLENLYNDRREAALADFNRAIAIDENYAWAYFQRGQVLRELGRLEESLDDLTRACDLEPDDPAYHAERGETLRMLRRHEA
AIEAFSRAIALRPEYPWALGSRGQVWRALRRHHEALVDFDAALALNPNLAWIHAERGESLRALNQHQEAIEAFSRALAID
PAYPWALGHRGITYREMRDFPAAIADFDAAIALQGNMAWLYAERGETRRLADDFEGALADLSRALELDSAYAWAFGSRGA
AFRAVGDLNAALADFNRALELDPGYTWVYFQRGLLHRNTNRTDEAIADFSRAIELEPNYIAALAERGELFRLQRRYEEAL
RDFNRTIELQPDHAWALGSRGQVYRVLARYDEALADFNRALALKPDMVWVIAERGETHRLLRNYNEALEDFNRALELSPN
DSWVLSRRGATYQSLKIYEEAYIDLTRAIEIDPNNAWAWAQRGSLFRQM

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI310110582, Length=424, Percent_Identity=25.4716981132075, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI310123097, Length=424, Percent_Identity=25.4716981132075, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI310131789, Length=424, Percent_Identity=25.4716981132075, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI32307150, Length=421, Percent_Identity=24.4655581947743, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI32307148, Length=421, Percent_Identity=24.4655581947743, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI170784867, Length=236, Percent_Identity=28.3898305084746, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI296531396, Length=199, Percent_Identity=26.6331658291457, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI225735593, Length=290, Percent_Identity=23.7931034482759, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI225735591, Length=290, Percent_Identity=23.7931034482759, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI7662078, Length=331, Percent_Identity=25.0755287009063, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI167466177, Length=202, Percent_Identity=24.2574257425743, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5453980, Length=353, Percent_Identity=22.9461756373938, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI167466175, Length=202, Percent_Identity=24.2574257425743, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=388, Percent_Identity=22.9381443298969, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI115532690, Length=388, Percent_Identity=22.9381443298969, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319387, Length=308, Percent_Identity=23.0519480519481, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17647755, Length=445, Percent_Identity=24.4943820224719, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24585827, Length=445, Percent_Identity=24.4943820224719, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24585829, Length=445, Percent_Identity=24.4943820224719, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19920486, Length=370, Percent_Identity=26.7567567567568, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI161076610, Length=370, Percent_Identity=26.7567567567568, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24659892, Length=286, Percent_Identity=23.7762237762238, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647123, Length=234, Percent_Identity=27.3504273504274, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355911, Length=119, Percent_Identity=31.9327731092437, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 51710; Mature: 51579

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLENLYNDRREAALADFNRAIAIDENYAWAYFQRGQVLRELGRLEESLDDLTRACDLEP
CCCHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DDPAYHAERGETLRMLRRHEAAIEAFSRAIALRPEYPWALGSRGQVWRALRRHHEALVDF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DAALALNPNLAWIHAERGESLRALNQHQEAIEAFSRALAIDPAYPWALGHRGITYREMRD
CHHEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCHHHHHH
FPAAIADFDAAIALQGNMAWLYAERGETRRLADDFEGALADLSRALELDSAYAWAFGSRG
HHHHHHCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCC
AAFRAVGDLNAALADFNRALELDPGYTWVYFQRGLLHRNTNRTDEAIADFSRAIELEPNY
CEEEEHHHHHHHHHHHHHCEECCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHEECCCHH
IAALAERGELFRLQRRYEEALRDFNRTIELQPDHAWALGSRGQVYRVLARYDEALADFNR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHH
ALALKPDMVWVIAERGETHRLLRNYNEALEDFNRALELSPNDSWVLSRRGATYQSLKIYE
HEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCHHHHHHHH
EAYIDLTRAIEIDPNNAWAWAQRGSLFRQM
HHHHEEEEEEEECCCCCEEHHHHCHHHHCC
>Mature Secondary Structure 
SLENLYNDRREAALADFNRAIAIDENYAWAYFQRGQVLRELGRLEESLDDLTRACDLEP
CCHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DDPAYHAERGETLRMLRRHEAAIEAFSRAIALRPEYPWALGSRGQVWRALRRHHEALVDF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DAALALNPNLAWIHAERGESLRALNQHQEAIEAFSRALAIDPAYPWALGHRGITYREMRD
CHHEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCHHHHHH
FPAAIADFDAAIALQGNMAWLYAERGETRRLADDFEGALADLSRALELDSAYAWAFGSRG
HHHHHHCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCC
AAFRAVGDLNAALADFNRALELDPGYTWVYFQRGLLHRNTNRTDEAIADFSRAIELEPNY
CEEEEHHHHHHHHHHHHHCEECCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHEECCCHH
IAALAERGELFRLQRRYEEALRDFNRTIELQPDHAWALGSRGQVYRVLARYDEALADFNR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHH
ALALKPDMVWVIAERGETHRLLRNYNEALEDFNRALELSPNDSWVLSRRGATYQSLKIYE
HEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCHHHHHHHH
EAYIDLTRAIEIDPNNAWAWAQRGSLFRQM
HHHHEEEEEEEECCCCCEEHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]