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The map label for this gene is pilH [H]

Identifier: 222525179

GI number: 222525179

Start: 2424853

End: 2425227

Strand: Direct

Name: pilH [H]

Synonym: Chy400_1917

Alternate gene names: 222525179

Gene position: 2424853-2425227 (Clockwise)

Preceding gene: 222525178

Following gene: 222525180

Centisome position: 46.02

GC content: 50.93

Gene sequence:

>375_bases
ATGGCAAAGATTCTGATCGTCGAAGATGATAGCAATAACCGGGACTTGATCGCACGTATCGTTGAACTCATGGGACATCA
GCCAATTCTGGCAATTGATGGGGCGCAGGGTGTTGCCCTGGCACGTAGTGAACAACCTGACTTGATCATCATGGATATGG
GTCTACCAGTGCTCAATGGCTGGCAGGCAACTCACCGTATTAAGTCGCAACCGGCAACCAGGCACATCCCTGTCCTGGCC
CTCACGGCATACGCGATGAATGAAGATCGGATACGGTCGTTGGTTGCAGGTTGTGATGATTTCGAGACCAAGCCGATTGA
TTTCAATCGCTTCCGTGAAAAGGTAGATGCATTACTTGCACGGCGGGTAGACTAG

Upstream 100 bases:

>100_bases
ACGCATATTCGCAACATGTTGACGCACGCTCGCTCAACTTCTGCTGATAGTACTATTTCGGGATAATCCCCTTACTATCA
CGGTGCTACCGGGTACACCT

Downstream 100 bases:

>100_bases
CGGCTGGTATGCTTGCCTGTGGTTGCCGTATATGGGTTCACCACAGAGGCACGGCGGGCACAGAGGTATATCGTGGTCGC
CCCGTTTCCTGTACGATGGG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MAKILIVEDDSNNRDLIARIVELMGHQPILAIDGAQGVALARSEQPDLIIMDMGLPVLNGWQATHRIKSQPATRHIPVLA
LTAYAMNEDRIRSLVAGCDDFETKPIDFNRFREKVDALLARRVD

Sequences:

>Translated_124_residues
MAKILIVEDDSNNRDLIARIVELMGHQPILAIDGAQGVALARSEQPDLIIMDMGLPVLNGWQATHRIKSQPATRHIPVLA
LTAYAMNEDRIRSLVAGCDDFETKPIDFNRFREKVDALLARRVD
>Mature_123_residues
AKILIVEDDSNNRDLIARIVELMGHQPILAIDGAQGVALARSEQPDLIIMDMGLPVLNGWQATHRIKSQPATRHIPVLAL
TAYAMNEDRIRSLVAGCDDFETKPIDFNRFREKVDALLARRVD

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=36.9747899159664, Blast_Score=81, Evalue=2e-17,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=36.1344537815126, Blast_Score=73, Evalue=7e-15,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=32.4786324786325, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=120, Percent_Identity=30.8333333333333, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=108, Percent_Identity=34.2592592592593, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=118, Percent_Identity=34.7457627118644, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1787375, Length=119, Percent_Identity=31.0924369747899, Blast_Score=60, Evalue=5e-11,
Organism=Escherichia coli, GI1786911, Length=121, Percent_Identity=31.404958677686, Blast_Score=60, Evalue=5e-11,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=30.2752293577982, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13872; Mature: 13741

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILIVEDDSNNRDLIARIVELMGHQPILAIDGAQGVALARSEQPDLIIMDMGLPVLNG
CCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCEEEEECCCCCCCC
WQATHRIKSQPATRHIPVLALTAYAMNEDRIRSLVAGCDDFETKPIDFNRFREKVDALLA
CHHHHHHHCCCCCCCCCCEEEEEHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RRVD
HCCC
>Mature Secondary Structure 
AKILIVEDDSNNRDLIARIVELMGHQPILAIDGAQGVALARSEQPDLIIMDMGLPVLNG
CEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCEEEEECCCCCCCC
WQATHRIKSQPATRHIPVLALTAYAMNEDRIRSLVAGCDDFETKPIDFNRFREKVDALLA
CHHHHHHHCCCCCCCCCCEEEEEHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RRVD
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]